Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9628
Gene name Gene Name - the full gene name approved by the HGNC.	Regulator of G protein signaling 6
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RGS6
Synonyms (NCBI Gene) Gene synonyms aliases	GAP, HA117, S914
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q24.2
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also

Show/Hide all(277)

miRTarBase ID	miRNA	Experiments	Reference
MIRT715447	hsa-miR-3681-3p	HITS-CLIP	19536157
MIRT715446	hsa-miR-216a-3p	HITS-CLIP	19536157
MIRT715445	hsa-miR-128-3p	HITS-CLIP	19536157
MIRT715444	hsa-miR-27b-3p	HITS-CLIP	19536157
MIRT715443	hsa-miR-27a-3p	HITS-CLIP	19536157
MIRT715442	hsa-miR-4639-3p	HITS-CLIP	19536157
MIRT715441	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT715440	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT715439	hsa-miR-4290	HITS-CLIP	19536157
MIRT715438	hsa-miR-513a-5p	HITS-CLIP	19536157
MIRT715437	hsa-miR-6794-3p	HITS-CLIP	19536157
MIRT715436	hsa-miR-4279	HITS-CLIP	19536157
MIRT715435	hsa-miR-3157-3p	HITS-CLIP	19536157
MIRT715434	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT715433	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT642676	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT642675	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT642674	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT642673	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT642672	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT642671	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT642670	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT642669	hsa-miR-204-3p	HITS-CLIP	23824327
MIRT642668	hsa-miR-4646-5p	HITS-CLIP	23824327
MIRT642667	hsa-miR-3192-5p	HITS-CLIP	23824327
MIRT642666	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT642665	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT642664	hsa-miR-3182	HITS-CLIP	23824327
MIRT642663	hsa-miR-1233-3p	HITS-CLIP	23824327
MIRT642662	hsa-miR-938	HITS-CLIP	23824327
MIRT642661	hsa-miR-4747-5p	HITS-CLIP	23824327
MIRT642660	hsa-miR-5196-5p	HITS-CLIP	23824327
MIRT642659	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT642658	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT642657	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT642656	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT495514	hsa-miR-4747-3p	PAR-CLIP	22291592
MIRT495513	hsa-miR-6760-5p	PAR-CLIP	22291592
MIRT495512	hsa-miR-1321	PAR-CLIP	22291592
MIRT495511	hsa-miR-4739	PAR-CLIP	22291592
MIRT495510	hsa-miR-4756-5p	PAR-CLIP	22291592
MIRT495509	hsa-miR-135a-3p	PAR-CLIP	22291592
MIRT495508	hsa-miR-765	PAR-CLIP	22291592
MIRT495507	hsa-miR-1289	PAR-CLIP	22291592
MIRT495506	hsa-miR-7106-5p	PAR-CLIP	22291592
MIRT495505	hsa-miR-3162-5p	PAR-CLIP	22291592
MIRT495504	hsa-miR-5571-3p	PAR-CLIP	22291592
MIRT443861	hsa-miR-6895-5p	PAR-CLIP	22100165
MIRT443860	hsa-miR-6838-3p	PAR-CLIP	22100165
MIRT443859	hsa-miR-3691-3p	PAR-CLIP	22100165
MIRT443858	hsa-miR-5090	PAR-CLIP	22100165
MIRT443856	hsa-miR-6775-5p	PAR-CLIP	22100165
MIRT443857	hsa-miR-4508	PAR-CLIP	22100165
MIRT443855	hsa-miR-4667-5p	PAR-CLIP	22100165
MIRT443854	hsa-miR-4700-5p	PAR-CLIP	22100165
MIRT443853	hsa-miR-8089	PAR-CLIP	22100165
MIRT443852	hsa-miR-4480	PAR-CLIP	22100165
MIRT443851	hsa-miR-4731-5p	PAR-CLIP	22100165
MIRT443850	hsa-miR-4505	PAR-CLIP	22100165
MIRT443849	hsa-miR-5787	PAR-CLIP	22100165
MIRT443848	hsa-miR-6731-5p	PAR-CLIP	22100165
MIRT443847	hsa-miR-8085	PAR-CLIP	22100165
MIRT443846	hsa-miR-4492	PAR-CLIP	22100165
MIRT443844	hsa-miR-4498	PAR-CLIP	22100165
MIRT443845	hsa-miR-5001-5p	PAR-CLIP	22100165
MIRT443843	hsa-miR-762	PAR-CLIP	22100165
MIRT443842	hsa-miR-3175	PAR-CLIP	22100165
MIRT443841	hsa-miR-1343-5p	PAR-CLIP	22100165
MIRT443840	hsa-miR-939-5p	PAR-CLIP	22100165
MIRT443839	hsa-miR-6825-5p	PAR-CLIP	22100165
MIRT443838	hsa-miR-185-3p	PAR-CLIP	22100165
MIRT443837	hsa-miR-6727-5p	PAR-CLIP	22100165
MIRT443836	hsa-miR-3150a-3p	PAR-CLIP	22100165
MIRT443835	hsa-miR-6763-5p	PAR-CLIP	22100165
MIRT715447	hsa-miR-3681-3p	HITS-CLIP	19536157
MIRT715446	hsa-miR-216a-3p	HITS-CLIP	19536157
MIRT715445	hsa-miR-128-3p	HITS-CLIP	19536157
MIRT715444	hsa-miR-27b-3p	HITS-CLIP	19536157
MIRT715443	hsa-miR-27a-3p	HITS-CLIP	19536157
MIRT715442	hsa-miR-4639-3p	HITS-CLIP	19536157
MIRT715441	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT715440	hsa-miR-130b-5p	HITS-CLIP	19536157
MIRT715439	hsa-miR-4290	HITS-CLIP	19536157
MIRT715438	hsa-miR-513a-5p	HITS-CLIP	19536157
MIRT715437	hsa-miR-6794-3p	HITS-CLIP	19536157
MIRT715436	hsa-miR-4279	HITS-CLIP	19536157
MIRT715435	hsa-miR-3157-3p	HITS-CLIP	19536157
MIRT715434	hsa-miR-874-3p	HITS-CLIP	19536157
MIRT715433	hsa-miR-629-3p	HITS-CLIP	19536157
MIRT642676	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT642675	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT642674	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT642673	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT642672	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT642671	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT642670	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT642669	hsa-miR-204-3p	HITS-CLIP	23824327
MIRT642668	hsa-miR-4646-5p	HITS-CLIP	23824327
MIRT642667	hsa-miR-3192-5p	HITS-CLIP	23824327
MIRT642666	hsa-miR-619-5p	HITS-CLIP	23824327
MIRT642665	hsa-miR-6506-5p	HITS-CLIP	23824327
MIRT642664	hsa-miR-3182	HITS-CLIP	23824327
MIRT642663	hsa-miR-1233-3p	HITS-CLIP	23824327
MIRT642662	hsa-miR-938	HITS-CLIP	23824327
MIRT642661	hsa-miR-4747-5p	HITS-CLIP	23824327
MIRT642660	hsa-miR-5196-5p	HITS-CLIP	23824327
MIRT642659	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT642658	hsa-miR-4755-5p	HITS-CLIP	23824327
MIRT642657	hsa-miR-5006-3p	HITS-CLIP	23824327
MIRT642656	hsa-miR-4446-5p	HITS-CLIP	23824327
MIRT495514	hsa-miR-4747-3p	PAR-CLIP	22291592
MIRT495513	hsa-miR-6760-5p	PAR-CLIP	22291592
MIRT495512	hsa-miR-1321	PAR-CLIP	22291592
MIRT495511	hsa-miR-4739	PAR-CLIP	22291592
MIRT495510	hsa-miR-4756-5p	PAR-CLIP	22291592
MIRT495509	hsa-miR-135a-3p	PAR-CLIP	22291592
MIRT495508	hsa-miR-765	PAR-CLIP	22291592
MIRT495507	hsa-miR-1289	PAR-CLIP	22291592
MIRT495506	hsa-miR-7106-5p	PAR-CLIP	22291592
MIRT495505	hsa-miR-3162-5p	PAR-CLIP	22291592
MIRT495504	hsa-miR-5571-3p	PAR-CLIP	22291592
MIRT443861	hsa-miR-6895-5p	PAR-CLIP	22100165
MIRT443860	hsa-miR-6838-3p	PAR-CLIP	22100165
MIRT443859	hsa-miR-3691-3p	PAR-CLIP	22100165
MIRT443858	hsa-miR-5090	PAR-CLIP	22100165
MIRT443856	hsa-miR-6775-5p	PAR-CLIP	22100165
MIRT443857	hsa-miR-4508	PAR-CLIP	22100165
MIRT443855	hsa-miR-4667-5p	PAR-CLIP	22100165
MIRT443854	hsa-miR-4700-5p	PAR-CLIP	22100165
MIRT443853	hsa-miR-8089	PAR-CLIP	22100165
MIRT443852	hsa-miR-4480	PAR-CLIP	22100165
MIRT443851	hsa-miR-4731-5p	PAR-CLIP	22100165
MIRT443850	hsa-miR-4505	PAR-CLIP	22100165
MIRT443849	hsa-miR-5787	PAR-CLIP	22100165
MIRT443848	hsa-miR-6731-5p	PAR-CLIP	22100165
MIRT443847	hsa-miR-8085	PAR-CLIP	22100165
MIRT443846	hsa-miR-4492	PAR-CLIP	22100165
MIRT443844	hsa-miR-4498	PAR-CLIP	22100165
MIRT443845	hsa-miR-5001-5p	PAR-CLIP	22100165
MIRT443843	hsa-miR-762	PAR-CLIP	22100165
MIRT443842	hsa-miR-3175	PAR-CLIP	22100165
MIRT443841	hsa-miR-1343-5p	PAR-CLIP	22100165
MIRT443840	hsa-miR-939-5p	PAR-CLIP	22100165
MIRT443839	hsa-miR-6825-5p	PAR-CLIP	22100165
MIRT443838	hsa-miR-185-3p	PAR-CLIP	22100165
MIRT443837	hsa-miR-6727-5p	PAR-CLIP	22100165
MIRT443836	hsa-miR-3150a-3p	PAR-CLIP	22100165
MIRT443835	hsa-miR-6763-5p	PAR-CLIP	22100165
MIRT1304485	hsa-miR-4701-5p	CLIP-seq
MIRT1304486	hsa-miR-588	CLIP-seq
MIRT1304487	hsa-miR-1972	CLIP-seq
MIRT1304488	hsa-miR-4687-3p	CLIP-seq
MIRT1304489	hsa-miR-647	CLIP-seq
MIRT1304490	hsa-let-7a	CLIP-seq
MIRT1304491	hsa-let-7b	CLIP-seq
MIRT1304492	hsa-let-7c	CLIP-seq
MIRT1304493	hsa-let-7d	CLIP-seq
MIRT1304494	hsa-let-7e	CLIP-seq
MIRT1304495	hsa-let-7f	CLIP-seq
MIRT1304496	hsa-let-7g	CLIP-seq
MIRT1304497	hsa-let-7i	CLIP-seq
MIRT1304498	hsa-miR-1224-3p	CLIP-seq
MIRT1304499	hsa-miR-1260	CLIP-seq
MIRT1304500	hsa-miR-1260b	CLIP-seq
MIRT1304501	hsa-miR-1280	CLIP-seq
MIRT1304502	hsa-miR-1294	CLIP-seq
MIRT1304503	hsa-miR-137	CLIP-seq
MIRT1304504	hsa-miR-1915	CLIP-seq
MIRT1304505	hsa-miR-196a	CLIP-seq
MIRT1304506	hsa-miR-196b	CLIP-seq
MIRT1304507	hsa-miR-202	CLIP-seq
MIRT1304508	hsa-miR-203	CLIP-seq
MIRT1304509	hsa-miR-3194-3p	CLIP-seq
MIRT1304510	hsa-miR-34a	CLIP-seq
MIRT1304511	hsa-miR-34c-5p	CLIP-seq
MIRT1304512	hsa-miR-3650	CLIP-seq
MIRT1304513	hsa-miR-3663-3p	CLIP-seq
MIRT1304514	hsa-miR-3665	CLIP-seq
MIRT1304515	hsa-miR-3934	CLIP-seq
MIRT1304516	hsa-miR-3944-5p	CLIP-seq
MIRT1304517	hsa-miR-4267	CLIP-seq
MIRT1304518	hsa-miR-4283	CLIP-seq
MIRT1304519	hsa-miR-4458	CLIP-seq
MIRT1304520	hsa-miR-4459	CLIP-seq
MIRT1304521	hsa-miR-4468	CLIP-seq
MIRT1304522	hsa-miR-4489	CLIP-seq
MIRT1304523	hsa-miR-449a	CLIP-seq
MIRT1304524	hsa-miR-449b	CLIP-seq
MIRT1304525	hsa-miR-4500	CLIP-seq
MIRT1304526	hsa-miR-4663	CLIP-seq
MIRT1304527	hsa-miR-4693-3p	CLIP-seq
MIRT1304528	hsa-miR-4695-5p	CLIP-seq
MIRT1304485	hsa-miR-4701-5p	CLIP-seq
MIRT1304529	hsa-miR-4710	CLIP-seq
MIRT1304530	hsa-miR-4726-3p	CLIP-seq
MIRT1304531	hsa-miR-4773	CLIP-seq
MIRT1304532	hsa-miR-4779	CLIP-seq
MIRT1304533	hsa-miR-4795-3p	CLIP-seq
MIRT1304534	hsa-miR-496	CLIP-seq
MIRT1304535	hsa-miR-532-3p	CLIP-seq
MIRT1304536	hsa-miR-586	CLIP-seq
MIRT1304486	hsa-miR-588	CLIP-seq
MIRT1304537	hsa-miR-605	CLIP-seq
MIRT1304538	hsa-miR-657	CLIP-seq
MIRT1304539	hsa-miR-665	CLIP-seq
MIRT1304540	hsa-miR-939	CLIP-seq
MIRT1304541	hsa-miR-98	CLIP-seq
MIRT2090209	hsa-miR-1184	CLIP-seq
MIRT2090210	hsa-miR-1205	CLIP-seq
MIRT2090211	hsa-miR-1254	CLIP-seq
MIRT2090212	hsa-miR-205	CLIP-seq
MIRT2090213	hsa-miR-3116	CLIP-seq
MIRT2090214	hsa-miR-3144-5p	CLIP-seq
MIRT2090215	hsa-miR-3158-5p	CLIP-seq
MIRT2090216	hsa-miR-3191	CLIP-seq
MIRT2090217	hsa-miR-320a	CLIP-seq
MIRT2090218	hsa-miR-320b	CLIP-seq
MIRT2090219	hsa-miR-320c	CLIP-seq
MIRT2090220	hsa-miR-320d	CLIP-seq
MIRT2090221	hsa-miR-3918	CLIP-seq
MIRT2090222	hsa-miR-4428	CLIP-seq
MIRT2090223	hsa-miR-4429	CLIP-seq
MIRT2090224	hsa-miR-4434	CLIP-seq
MIRT2090225	hsa-miR-4516	CLIP-seq
MIRT2090226	hsa-miR-4652-5p	CLIP-seq
MIRT2090227	hsa-miR-4768-3p	CLIP-seq
MIRT2090228	hsa-miR-515-3p	CLIP-seq
MIRT2090229	hsa-miR-519e	CLIP-seq
MIRT2090230	hsa-miR-550a	CLIP-seq
MIRT1304538	hsa-miR-657	CLIP-seq
MIRT2090231	hsa-miR-661	CLIP-seq
MIRT1304539	hsa-miR-665	CLIP-seq
MIRT2314969	hsa-miR-1233	CLIP-seq
MIRT2314970	hsa-miR-129-3p	CLIP-seq
MIRT2314971	hsa-miR-1304	CLIP-seq
MIRT1304504	hsa-miR-1915	CLIP-seq
MIRT2314972	hsa-miR-2467-5p	CLIP-seq
MIRT2314973	hsa-miR-3154	CLIP-seq
MIRT2314974	hsa-miR-3166	CLIP-seq
MIRT2314975	hsa-miR-3179	CLIP-seq
MIRT2314976	hsa-miR-3188	CLIP-seq
MIRT2314977	hsa-miR-3190	CLIP-seq
MIRT2090217	hsa-miR-320a	CLIP-seq
MIRT2090218	hsa-miR-320b	CLIP-seq
MIRT2090219	hsa-miR-320c	CLIP-seq
MIRT2090220	hsa-miR-320d	CLIP-seq
MIRT2314978	hsa-miR-376c	CLIP-seq
MIRT2314979	hsa-miR-3975	CLIP-seq
MIRT2314980	hsa-miR-4311	CLIP-seq
MIRT2090223	hsa-miR-4429	CLIP-seq
MIRT2314981	hsa-miR-4448	CLIP-seq
MIRT2314982	hsa-miR-4660	CLIP-seq
MIRT1304530	hsa-miR-4726-3p	CLIP-seq
MIRT2314983	hsa-miR-4755-3p	CLIP-seq
MIRT2090227	hsa-miR-4768-3p	CLIP-seq
MIRT2314984	hsa-miR-485-5p	CLIP-seq
MIRT2314985	hsa-miR-635	CLIP-seq
MIRT1304539	hsa-miR-665	CLIP-seq
MIRT2314986	hsa-miR-671-5p	CLIP-seq
MIRT1304540	hsa-miR-939	CLIP-seq
MIRT2458152	hsa-miR-1262	CLIP-seq
MIRT2458153	hsa-miR-1293	CLIP-seq
MIRT2458154	hsa-miR-4259	CLIP-seq
MIRT2458155	hsa-miR-4483	CLIP-seq
MIRT2458156	hsa-miR-4640-5p	CLIP-seq
MIRT2458157	hsa-miR-4701-3p	CLIP-seq
MIRT2458158	hsa-miR-4726-5p	CLIP-seq
MIRT2611333	hsa-miR-1292	CLIP-seq
MIRT2611334	hsa-miR-370	CLIP-seq
MIRT2611335	hsa-miR-4471	CLIP-seq
MIRT2611336	hsa-miR-4763-5p	CLIP-seq
MIRT2090230	hsa-miR-550a	CLIP-seq
MIRT2611333	hsa-miR-1292	CLIP-seq
MIRT2611334	hsa-miR-370	CLIP-seq
MIRT2611335	hsa-miR-4471	CLIP-seq
MIRT2611336	hsa-miR-4763-5p	CLIP-seq
MIRT2090230	hsa-miR-550a	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003924	Function	GTPase activity	TAS
GO:0005096	Function	GTPase activator activity	IDA	10521509
GO:0005515	Function	Protein binding	IPI	22939624
GO:0005634	Component	Nucleus	IEA
GO:0005829	Component	Cytosol	IDA	10521509
GO:0005886	Component	Plasma membrane	TAS
GO:0007186	Process	G protein-coupled receptor signaling pathway	TAS
GO:0008277	Process	Regulation of G protein-coupled receptor signaling pathway	TAS	10083744
GO:0009968	Process	Negative regulation of signal transduction	IEA
GO:0019898	Component	Extrinsic component of membrane	IDA	10521509
GO:0035556	Process	Intracellular signal transduction	IEA
GO:0043547	Process	Positive regulation of GTPase activity	IDA	10521509

MIM	HGNC	e!Ensembl
603894	10002	ENSG00000182732

Protein

UniProt ID

P49758

Protein name

Regulator of G-protein signaling 6 (RGS6) (S914)

Protein function

Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. The RGS6/GNB5 dimer enhances GNAO1 GTPa

PDB

2ES0

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00610	DEP	43 → 113	Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)	Domain
PF18148	RGS_DHEX	116 → 217	Regulator of G-protein signalling DHEX domain	Domain
PF00631	G-gamma	255 → 319	GGL domain	Domain
PF00615	RGS	336 → 450	Regulator of G protein signaling domain	Domain

Sequence

MAQGSGDQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGVPIRTVKSFLSKIPSVV
TGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVLTMKDDGTFYRFQAPYFWP
SNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQRAFARKWEFIFMQAEAQVKI
DRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIRKCRRLKNPQKVKKSVYGVTEES
QAQSPVHVLSQPIRKTTKEDIRKQITFLNAQIDRHCLKMSKVAESLIAYTEQYVEYDPLI
TPAEPSNPWISDDVALWDIEMSKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSS
ENLRFWLAVQDLKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRY
TFEDAQEHIYKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS

Sequence length

472

Interactions

View interactions

	Reactome
			G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Duchenne muscular dystrophy	Muscular Dystrophy, Duchenne	rs128625226, rs128625227, rs128625228, rs128625229, rs2147483647, rs104894787, rs128625230, rs128626234, rs201366610, rs267606770, rs128626235, rs128626231, rs146071084, rs128626232, rs104894788 View all (641 more)	30014611
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	26626624
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	28991256, 26821981, 29483656, 30285260, 28540026, 31374203, 31268507, 25056061, 26198764

Show/Hide Unknown Diseases (4)

Disease term	Disease name	Evidence	Source
Unknown
Neuroticism	Neuroticism		GWAS
Intracranial Aneurysm	Intracranial Aneurysm		GWAS
Prostate cancer	Prostate cancer	Together, these results show that PRRX2 is an oncogene and might play a role in the aggressiveness of PC within the DNPC population.	GWAS, CBGDA
Glioblastoma	Glioblastoma	CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587	GWAS, CBGDA

Show/Hide Text Mining Associations (20)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenoma	Associate	34092617
Breast Neoplasms	Associate	20642825
Breast Neoplasms	Inhibit	35902557
Carcinoma Non Small Cell Lung	Associate	35902557
Colorectal Neoplasms	Associate	34092617
Hirschsprung Disease	Associate	25120773, 26097584
Leukemia	Associate	19435509
Leukemia Myeloid Acute	Inhibit	28665981
Leukemia Promyelocytic Acute	Inhibit	28665981
Lung Neoplasms	Inhibit	35902557
Neoplasm Metastasis	Associate	35902557
Neoplasms	Associate	25120791
Neoplasms	Inhibit	35902557
Neoplasms Adipose Tissue	Associate	19461586, 21233807
Obesity	Associate	28090039
Obesity Abdominal	Associate	28090039
Pancreatic Neoplasms	Associate	25120791
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	24159609
Sarcopenia	Associate	36573383
Urinary Bladder Neoplasms	Associate	35902557

RGS6 (regulator of G protein signaling 6)