Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9623
Gene name Gene Name - the full gene name approved by the HGNC.	TCL1 family AKT coactivator B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TCL1B
Synonyms (NCBI Gene) Gene synonyms aliases	SYN-1, TML1
Chromosome Chromosome number	14
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	14q32.13

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021345	hsa-miR-9-5p	Microarray	17612493
MIRT025631	hsa-miR-7-5p	Microarray	17612493
MIRT1416621	hsa-miR-1470	CLIP-seq
MIRT1416622	hsa-miR-3184	CLIP-seq
MIRT1416623	hsa-miR-3944-5p	CLIP-seq
MIRT1416624	hsa-miR-423-5p	CLIP-seq
MIRT1416625	hsa-miR-4286	CLIP-seq
MIRT1416626	hsa-miR-4420	CLIP-seq
MIRT1416627	hsa-miR-4667-3p	CLIP-seq
MIRT1416628	hsa-miR-4699-5p	CLIP-seq
MIRT2124927	hsa-miR-1207-5p	CLIP-seq
MIRT2124928	hsa-miR-1972	CLIP-seq
MIRT2124929	hsa-miR-214	CLIP-seq
MIRT2124930	hsa-miR-3194-5p	CLIP-seq
MIRT2124931	hsa-miR-3619-5p	CLIP-seq
MIRT2124932	hsa-miR-3918	CLIP-seq
MIRT2124933	hsa-miR-3926	CLIP-seq
MIRT2124934	hsa-miR-4291	CLIP-seq
MIRT2124935	hsa-miR-4530	CLIP-seq
MIRT2124936	hsa-miR-4640-5p	CLIP-seq
MIRT2124937	hsa-miR-4726-5p	CLIP-seq
MIRT2124938	hsa-miR-4763-3p	CLIP-seq
MIRT2124939	hsa-miR-761	CLIP-seq
MIRT2124940	hsa-miR-922	CLIP-seq
MIRT2124927	hsa-miR-1207-5p	CLIP-seq
MIRT2347374	hsa-miR-1287	CLIP-seq
MIRT2347375	hsa-miR-1827	CLIP-seq
MIRT2124928	hsa-miR-1972	CLIP-seq
MIRT2124929	hsa-miR-214	CLIP-seq
MIRT2347376	hsa-miR-3135b	CLIP-seq
MIRT2347377	hsa-miR-342-5p	CLIP-seq
MIRT2347378	hsa-miR-3612	CLIP-seq
MIRT2124931	hsa-miR-3619-5p	CLIP-seq
MIRT2124932	hsa-miR-3918	CLIP-seq
MIRT2347379	hsa-miR-4443	CLIP-seq
MIRT2124935	hsa-miR-4530	CLIP-seq
MIRT2124936	hsa-miR-4640-5p	CLIP-seq
MIRT2347380	hsa-miR-4664-5p	CLIP-seq
MIRT2124937	hsa-miR-4726-5p	CLIP-seq
MIRT2347381	hsa-miR-4738-3p	CLIP-seq
MIRT2124938	hsa-miR-4763-3p	CLIP-seq
MIRT2347382	hsa-miR-4793-3p	CLIP-seq
MIRT2347383	hsa-miR-4793-5p	CLIP-seq
MIRT2347384	hsa-miR-637	CLIP-seq
MIRT2347385	hsa-miR-650	CLIP-seq
MIRT2124939	hsa-miR-761	CLIP-seq
MIRT2347386	hsa-miR-892b	CLIP-seq
MIRT2347387	hsa-miR-940	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183
GO:0019901	Function	Protein kinase binding	IPI	10983986
GO:0035556	Process	Intracellular signal transduction	IBA
GO:0035556	Process	Intracellular signal transduction	IDA	10983986
GO:0043539	Function	Protein serine/threonine kinase activator activity	IBA
GO:0043539	Function	Protein serine/threonine kinase activator activity	IDA	10983986
GO:0043539	Function	Protein serine/threonine kinase activator activity	IEA

MIM	HGNC	e!Ensembl
603769	11649	ENSG00000213231

Protein

UniProt ID

O95988

Protein name

T-cell leukemia/lymphoma protein 1B (Oncogene TCL-1B) (Oncogene TCL1B) (SYN-1) (Syncytiotrophoblast-specific protein) (TCL1/MTCP1-like protein 1)

Protein function

Enhances the phosphorylation and activation of AKT1 and AKT2.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01840	TCL1_MTCP1	1 → 124	TCL1/MTCP1 family	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in a variety of tissues including placenta and testis. {ECO:0000269|PubMed:10077617, ECO:0000269|PubMed:10344735}.

Sequence

MASEASVRLGVPPGRLWIQRPGIYEDEEGRTWVTVVVRFNPSRREWARASQGSRYEPSIT
VHLWQMAVHTRELLSSGQMPFSQLPAVWQLYPGRKYRAADSSFWEIADHGQIDSMEQLVL
TYQPERKD

Sequence length

128

Interactions

View interactions

	KEGG
	PI3K-Akt signaling pathway

TCL1B (TCL1 family AKT coactivator B)