AKAP12 (A-kinase anchoring protein 12)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9590 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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A-kinase anchoring protein 12 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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AKAP12 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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AKAP250, SSeCKS |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6q25.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||
| UniProt ID | Q02952 | |||||||||||||||||||||||||
| Protein name | A-kinase anchor protein 12 (AKAP-12) (A-kinase anchor protein 250 kDa) (AKAP 250) (Gravin) (Myasthenia gravis autoantigen) | |||||||||||||||||||||||||
| Protein function | Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC). | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in endothelial cells, cultured fibroblasts and osteosarcoma, but not in platelets, leukocytes, monocytic cell lines or peripherical blood cells. | |||||||||||||||||||||||||
| Sequence |
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| Sequence length | 1782 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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