SOX13 (SRY-box transcription factor 13)

Gene

• Entrez ID: 9580
• Gene name: SRY-box transcription factor 13
• Gene symbol: SOX13
• Synonyms (NCBI Gene): ICA12, Sox-13
• Chromosome: 1
• Chromosome location: 1q32.1
• Summary: This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The encoded protein may act as a transcriptional regulator after forming

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT016882	hsa-miR-335-5p	Microarray	18185580
MIRT052343	hsa-let-7b-5p	CLASH	23622248
MIRT734063	hsa-let-7c-3p	Immunohistochemistry (IHC), Microarray, qRT-PCR	33424970
MIRT734064	hsa-miR-135b-3p	Immunohistochemistry (IHC), Microarray, qRT-PCR	33424970
MIRT1380330	hsa-miR-1225-3p	CLIP-seq
MIRT1380331	hsa-miR-1233	CLIP-seq
MIRT1380332	hsa-miR-1253	CLIP-seq
MIRT1380333	hsa-miR-1291	CLIP-seq
MIRT1380334	hsa-miR-146b-3p	CLIP-seq
MIRT1380335	hsa-miR-185	CLIP-seq
MIRT1380336	hsa-miR-1912	CLIP-seq
MIRT1380337	hsa-miR-1915	CLIP-seq
MIRT1380338	hsa-miR-2110	CLIP-seq
MIRT1380339	hsa-miR-2392	CLIP-seq
MIRT1380340	hsa-miR-3123	CLIP-seq
MIRT1380341	hsa-miR-3126-3p	CLIP-seq
MIRT1380342	hsa-miR-3144-5p	CLIP-seq
MIRT1380343	hsa-miR-3150a-3p	CLIP-seq
MIRT1380344	hsa-miR-3162-5p	CLIP-seq
MIRT1380345	hsa-miR-3166	CLIP-seq
MIRT1380346	hsa-miR-3170	CLIP-seq
MIRT1380347	hsa-miR-3176	CLIP-seq
MIRT1380348	hsa-miR-3179	CLIP-seq
MIRT1380349	hsa-miR-3191	CLIP-seq
MIRT1380350	hsa-miR-328	CLIP-seq
MIRT1380351	hsa-miR-3605-5p	CLIP-seq
MIRT1380352	hsa-miR-361-3p	CLIP-seq
MIRT1380353	hsa-miR-3616-3p	CLIP-seq
MIRT1380354	hsa-miR-3688-3p	CLIP-seq
MIRT1380355	hsa-miR-376c	CLIP-seq
MIRT1380356	hsa-miR-3919	CLIP-seq
MIRT1380357	hsa-miR-3922-3p	CLIP-seq
MIRT1380358	hsa-miR-4260	CLIP-seq
MIRT1380359	hsa-miR-4261	CLIP-seq
MIRT1380360	hsa-miR-4306	CLIP-seq
MIRT1380361	hsa-miR-4311	CLIP-seq
MIRT1380362	hsa-miR-4433	CLIP-seq
MIRT1380363	hsa-miR-4436a	CLIP-seq
MIRT1380364	hsa-miR-4436b-3p	CLIP-seq
MIRT1380365	hsa-miR-4459	CLIP-seq
MIRT1380366	hsa-miR-4502	CLIP-seq
MIRT1380367	hsa-miR-4504	CLIP-seq
MIRT1380368	hsa-miR-4534	CLIP-seq
MIRT1380369	hsa-miR-4642	CLIP-seq
MIRT1380370	hsa-miR-4644	CLIP-seq
MIRT1380371	hsa-miR-4648	CLIP-seq
MIRT1380372	hsa-miR-4652-5p	CLIP-seq
MIRT1380373	hsa-miR-4654	CLIP-seq
MIRT1380374	hsa-miR-4685-5p	CLIP-seq
MIRT1380375	hsa-miR-4722-5p	CLIP-seq
MIRT1380376	hsa-miR-4728-5p	CLIP-seq
MIRT1380377	hsa-miR-4769-5p	CLIP-seq
MIRT1380378	hsa-miR-483-5p	CLIP-seq
MIRT1380379	hsa-miR-486-3p	CLIP-seq
MIRT1380380	hsa-miR-495	CLIP-seq
MIRT1380381	hsa-miR-520a-5p	CLIP-seq
MIRT1380382	hsa-miR-525-5p	CLIP-seq
MIRT1380383	hsa-miR-583	CLIP-seq
MIRT1380384	hsa-miR-758	CLIP-seq
MIRT1380385	hsa-miR-765	CLIP-seq
MIRT2113828	hsa-let-7a	CLIP-seq
MIRT2113829	hsa-let-7b	CLIP-seq
MIRT2113830	hsa-let-7c	CLIP-seq
MIRT2113831	hsa-let-7d	CLIP-seq
MIRT2113832	hsa-let-7e	CLIP-seq
MIRT2113833	hsa-let-7f	CLIP-seq
MIRT2113834	hsa-let-7g	CLIP-seq
MIRT2113835	hsa-let-7i	CLIP-seq
MIRT2113836	hsa-miR-1245b-3p	CLIP-seq
MIRT2113837	hsa-miR-1254	CLIP-seq
MIRT2113838	hsa-miR-1257	CLIP-seq
MIRT2113839	hsa-miR-1302	CLIP-seq
MIRT2113840	hsa-miR-143	CLIP-seq
MIRT1380336	hsa-miR-1912	CLIP-seq
MIRT1380337	hsa-miR-1915	CLIP-seq
MIRT1380338	hsa-miR-2110	CLIP-seq
MIRT2113841	hsa-miR-29a	CLIP-seq
MIRT2113842	hsa-miR-29b	CLIP-seq
MIRT2113843	hsa-miR-29c	CLIP-seq
MIRT2113844	hsa-miR-3116	CLIP-seq
MIRT2113845	hsa-miR-3120-3p	CLIP-seq
MIRT2113846	hsa-miR-3121-3p	CLIP-seq
MIRT2113847	hsa-miR-3122	CLIP-seq
MIRT1380340	hsa-miR-3123	CLIP-seq
MIRT1380342	hsa-miR-3144-5p	CLIP-seq
MIRT1380343	hsa-miR-3150a-3p	CLIP-seq
MIRT1380348	hsa-miR-3179	CLIP-seq
MIRT1380349	hsa-miR-3191	CLIP-seq
MIRT2113848	hsa-miR-3202	CLIP-seq
MIRT2113849	hsa-miR-329	CLIP-seq
MIRT1380353	hsa-miR-3616-3p	CLIP-seq
MIRT2113850	hsa-miR-362-3p	CLIP-seq
MIRT2113851	hsa-miR-3649	CLIP-seq
MIRT2113852	hsa-miR-3663-3p	CLIP-seq
MIRT2113853	hsa-miR-3908	CLIP-seq
MIRT2113854	hsa-miR-3913-5p	CLIP-seq
MIRT1380356	hsa-miR-3919	CLIP-seq
MIRT2113855	hsa-miR-3939	CLIP-seq
MIRT2113856	hsa-miR-3942-5p	CLIP-seq
MIRT2113857	hsa-miR-3944-5p	CLIP-seq
MIRT1380358	hsa-miR-4260	CLIP-seq
MIRT2113858	hsa-miR-4270	CLIP-seq
MIRT2113859	hsa-miR-4298	CLIP-seq
MIRT2113860	hsa-miR-4307	CLIP-seq
MIRT1380361	hsa-miR-4311	CLIP-seq
MIRT2113861	hsa-miR-4425	CLIP-seq
MIRT2113862	hsa-miR-4441	CLIP-seq
MIRT2113863	hsa-miR-4458	CLIP-seq
MIRT2113864	hsa-miR-4476	CLIP-seq
MIRT2113865	hsa-miR-4500	CLIP-seq
MIRT2113866	hsa-miR-4505	CLIP-seq
MIRT2113867	hsa-miR-450b-3p	CLIP-seq
MIRT2113868	hsa-miR-4512	CLIP-seq
MIRT1380369	hsa-miR-4642	CLIP-seq
MIRT1380372	hsa-miR-4652-5p	CLIP-seq
MIRT1380373	hsa-miR-4654	CLIP-seq
MIRT2113869	hsa-miR-4703-5p	CLIP-seq
MIRT2113870	hsa-miR-4709-5p	CLIP-seq
MIRT2113871	hsa-miR-4713-3p	CLIP-seq
MIRT1380375	hsa-miR-4722-5p	CLIP-seq
MIRT2113872	hsa-miR-4727-3p	CLIP-seq
MIRT2113873	hsa-miR-4756-3p	CLIP-seq
MIRT2113874	hsa-miR-4766-3p	CLIP-seq
MIRT1380377	hsa-miR-4769-5p	CLIP-seq
MIRT2113875	hsa-miR-4770	CLIP-seq
MIRT2113876	hsa-miR-4772-5p	CLIP-seq
MIRT2113877	hsa-miR-4786-3p	CLIP-seq
MIRT2113878	hsa-miR-4789-3p	CLIP-seq
MIRT2113879	hsa-miR-494	CLIP-seq
MIRT2113880	hsa-miR-512-5p	CLIP-seq
MIRT1380381	hsa-miR-520a-5p	CLIP-seq
MIRT1380382	hsa-miR-525-5p	CLIP-seq
MIRT2113881	hsa-miR-539	CLIP-seq
MIRT2113882	hsa-miR-545	CLIP-seq
MIRT2113883	hsa-miR-564	CLIP-seq
MIRT2113884	hsa-miR-581	CLIP-seq
MIRT2113885	hsa-miR-582-5p	CLIP-seq
MIRT1380383	hsa-miR-583	CLIP-seq
MIRT2113886	hsa-miR-638	CLIP-seq
MIRT2113887	hsa-miR-767-5p	CLIP-seq
MIRT2113888	hsa-miR-769-3p	CLIP-seq
MIRT2113889	hsa-miR-873	CLIP-seq
MIRT2113890	hsa-miR-939	CLIP-seq
MIRT2113891	hsa-miR-98	CLIP-seq
MIRT2113828	hsa-let-7a	CLIP-seq
MIRT2113829	hsa-let-7b	CLIP-seq
MIRT2113830	hsa-let-7c	CLIP-seq
MIRT2113831	hsa-let-7d	CLIP-seq
MIRT2113832	hsa-let-7e	CLIP-seq
MIRT2113833	hsa-let-7f	CLIP-seq
MIRT2113834	hsa-let-7g	CLIP-seq
MIRT2113835	hsa-let-7i	CLIP-seq
MIRT2336761	hsa-miR-1205	CLIP-seq
MIRT2336762	hsa-miR-1207-5p	CLIP-seq
MIRT1380330	hsa-miR-1225-3p	CLIP-seq
MIRT1380331	hsa-miR-1233	CLIP-seq
MIRT2113836	hsa-miR-1245b-3p	CLIP-seq
MIRT2113837	hsa-miR-1254	CLIP-seq
MIRT2113838	hsa-miR-1257	CLIP-seq
MIRT2336763	hsa-miR-125a-3p	CLIP-seq
MIRT2336764	hsa-miR-1275	CLIP-seq
MIRT2336765	hsa-miR-1286	CLIP-seq
MIRT2336766	hsa-miR-1293	CLIP-seq
MIRT2113839	hsa-miR-1302	CLIP-seq
MIRT2113840	hsa-miR-143	CLIP-seq
MIRT1380336	hsa-miR-1912	CLIP-seq
MIRT1380337	hsa-miR-1915	CLIP-seq
MIRT1380338	hsa-miR-2110	CLIP-seq
MIRT2336767	hsa-miR-2114	CLIP-seq
MIRT2336768	hsa-miR-2467-3p	CLIP-seq
MIRT2113841	hsa-miR-29a	CLIP-seq
MIRT2113842	hsa-miR-29b	CLIP-seq
MIRT2113843	hsa-miR-29c	CLIP-seq
MIRT2113844	hsa-miR-3116	CLIP-seq
MIRT2113845	hsa-miR-3120-3p	CLIP-seq
MIRT2113846	hsa-miR-3121-3p	CLIP-seq
MIRT2113847	hsa-miR-3122	CLIP-seq
MIRT1380340	hsa-miR-3123	CLIP-seq
MIRT1380342	hsa-miR-3144-5p	CLIP-seq
MIRT1380343	hsa-miR-3150a-3p	CLIP-seq
MIRT2336769	hsa-miR-3150b-3p	CLIP-seq
MIRT1380344	hsa-miR-3162-5p	CLIP-seq
MIRT2336770	hsa-miR-3165	CLIP-seq
MIRT2336771	hsa-miR-3184	CLIP-seq
MIRT2336772	hsa-miR-3187-3p	CLIP-seq
MIRT1380349	hsa-miR-3191	CLIP-seq
MIRT2113849	hsa-miR-329	CLIP-seq
MIRT2336773	hsa-miR-331-3p	CLIP-seq
MIRT2336774	hsa-miR-3611	CLIP-seq
MIRT2336775	hsa-miR-3612	CLIP-seq
MIRT1380352	hsa-miR-361-3p	CLIP-seq
MIRT1380353	hsa-miR-3616-3p	CLIP-seq
MIRT2113850	hsa-miR-362-3p	CLIP-seq
MIRT2336776	hsa-miR-3652	CLIP-seq
MIRT2336777	hsa-miR-3657	CLIP-seq
MIRT2113852	hsa-miR-3663-3p	CLIP-seq
MIRT2336778	hsa-miR-3665	CLIP-seq
MIRT2336779	hsa-miR-3677-3p	CLIP-seq
MIRT2336780	hsa-miR-3678-3p	CLIP-seq
MIRT2336781	hsa-miR-3691-3p	CLIP-seq
MIRT1380355	hsa-miR-376c	CLIP-seq
MIRT2336782	hsa-miR-383	CLIP-seq
MIRT2113853	hsa-miR-3908	CLIP-seq
MIRT2113854	hsa-miR-3913-5p	CLIP-seq
MIRT1380356	hsa-miR-3919	CLIP-seq
MIRT2336783	hsa-miR-3929	CLIP-seq
MIRT2113856	hsa-miR-3942-5p	CLIP-seq
MIRT2113857	hsa-miR-3944-5p	CLIP-seq
MIRT2336784	hsa-miR-3976	CLIP-seq
MIRT2336785	hsa-miR-423-5p	CLIP-seq
MIRT2336786	hsa-miR-4257	CLIP-seq
MIRT1380358	hsa-miR-4260	CLIP-seq
MIRT2336787	hsa-miR-4294	CLIP-seq
MIRT2113859	hsa-miR-4298	CLIP-seq
MIRT1380361	hsa-miR-4311	CLIP-seq
MIRT2336788	hsa-miR-432	CLIP-seq
MIRT2336789	hsa-miR-4419b	CLIP-seq
MIRT2336790	hsa-miR-4421	CLIP-seq
MIRT2113861	hsa-miR-4425	CLIP-seq
MIRT2336791	hsa-miR-4430	CLIP-seq
MIRT1380362	hsa-miR-4433	CLIP-seq
MIRT1380364	hsa-miR-4436b-3p	CLIP-seq
MIRT2336792	hsa-miR-4443	CLIP-seq
MIRT2336793	hsa-miR-4446-3p	CLIP-seq
MIRT2336794	hsa-miR-4447	CLIP-seq
MIRT2113863	hsa-miR-4458	CLIP-seq
MIRT2336795	hsa-miR-4469	CLIP-seq
MIRT2336796	hsa-miR-4472	CLIP-seq
MIRT2336797	hsa-miR-4475	CLIP-seq
MIRT2113864	hsa-miR-4476	CLIP-seq
MIRT2336798	hsa-miR-4478	CLIP-seq
MIRT2336799	hsa-miR-4481	CLIP-seq
MIRT2336800	hsa-miR-4483	CLIP-seq
MIRT2336801	hsa-miR-4484	CLIP-seq
MIRT2336802	hsa-miR-4492	CLIP-seq
MIRT2336803	hsa-miR-4494	CLIP-seq
MIRT2336804	hsa-miR-4498	CLIP-seq
MIRT2336805	hsa-miR-4499	CLIP-seq
MIRT2113865	hsa-miR-4500	CLIP-seq
MIRT1380366	hsa-miR-4502	CLIP-seq
MIRT1380367	hsa-miR-4504	CLIP-seq
MIRT2113866	hsa-miR-4505	CLIP-seq
MIRT2336806	hsa-miR-4509	CLIP-seq
MIRT2113867	hsa-miR-450b-3p	CLIP-seq
MIRT2113868	hsa-miR-4512	CLIP-seq
MIRT2336807	hsa-miR-4513	CLIP-seq
MIRT2336808	hsa-miR-4514	CLIP-seq
MIRT2336809	hsa-miR-4525	CLIP-seq
MIRT2336810	hsa-miR-4529-5p	CLIP-seq
MIRT2336811	hsa-miR-4641	CLIP-seq
MIRT1380369	hsa-miR-4642	CLIP-seq
MIRT1380372	hsa-miR-4652-5p	CLIP-seq
MIRT1380373	hsa-miR-4654	CLIP-seq
MIRT2336812	hsa-miR-4655-3p	CLIP-seq
MIRT2336813	hsa-miR-4665-5p	CLIP-seq
MIRT1380374	hsa-miR-4685-5p	CLIP-seq
MIRT2336814	hsa-miR-4688	CLIP-seq
MIRT2336815	hsa-miR-4692	CLIP-seq
MIRT2113869	hsa-miR-4703-5p	CLIP-seq
MIRT2336816	hsa-miR-4710	CLIP-seq
MIRT2113871	hsa-miR-4713-3p	CLIP-seq
MIRT2336817	hsa-miR-4714-3p	CLIP-seq
MIRT1380375	hsa-miR-4722-5p	CLIP-seq
MIRT2336818	hsa-miR-4723-5p	CLIP-seq
MIRT2336819	hsa-miR-4726-3p	CLIP-seq
MIRT2113872	hsa-miR-4727-3p	CLIP-seq
MIRT1380376	hsa-miR-4728-5p	CLIP-seq
MIRT2336820	hsa-miR-4736	CLIP-seq
MIRT2336821	hsa-miR-4738-3p	CLIP-seq
MIRT2336822	hsa-miR-4745-5p	CLIP-seq
MIRT2113873	hsa-miR-4756-3p	CLIP-seq
MIRT2336823	hsa-miR-4760-5p	CLIP-seq
MIRT2336824	hsa-miR-4763-3p	CLIP-seq
MIRT2113874	hsa-miR-4766-3p	CLIP-seq
MIRT2336825	hsa-miR-4768-3p	CLIP-seq
MIRT1380377	hsa-miR-4769-5p	CLIP-seq
MIRT2113875	hsa-miR-4770	CLIP-seq
MIRT2113876	hsa-miR-4772-5p	CLIP-seq
MIRT2336826	hsa-miR-4784	CLIP-seq
MIRT2336827	hsa-miR-485-3p	CLIP-seq
MIRT2336828	hsa-miR-485-5p	CLIP-seq
MIRT1380379	hsa-miR-486-3p	CLIP-seq
MIRT1380380	hsa-miR-495	CLIP-seq
MIRT2113880	hsa-miR-512-5p	CLIP-seq
MIRT2336829	hsa-miR-513c	CLIP-seq
MIRT2336830	hsa-miR-514b-5p	CLIP-seq
MIRT1380381	hsa-miR-520a-5p	CLIP-seq
MIRT1380382	hsa-miR-525-5p	CLIP-seq
MIRT2113881	hsa-miR-539	CLIP-seq
MIRT2113882	hsa-miR-545	CLIP-seq
MIRT2336831	hsa-miR-548an	CLIP-seq
MIRT2113883	hsa-miR-564	CLIP-seq
MIRT2336832	hsa-miR-570	CLIP-seq
MIRT2113884	hsa-miR-581	CLIP-seq
MIRT1380383	hsa-miR-583	CLIP-seq
MIRT2336833	hsa-miR-625	CLIP-seq
MIRT2113886	hsa-miR-638	CLIP-seq
MIRT2336834	hsa-miR-650	CLIP-seq
MIRT2336835	hsa-miR-665	CLIP-seq
MIRT1380384	hsa-miR-758	CLIP-seq
MIRT2336836	hsa-miR-759	CLIP-seq
MIRT2336837	hsa-miR-762	CLIP-seq
MIRT2113887	hsa-miR-767-5p	CLIP-seq
MIRT2113888	hsa-miR-769-3p	CLIP-seq
MIRT2113889	hsa-miR-873	CLIP-seq
MIRT2336838	hsa-miR-924	CLIP-seq
MIRT2336839	hsa-miR-940	CLIP-seq
MIRT2113891	hsa-miR-98	CLIP-seq
MIRT2113846	hsa-miR-3121-3p	CLIP-seq
MIRT2336780	hsa-miR-3678-3p	CLIP-seq
MIRT1380361	hsa-miR-4311	CLIP-seq
MIRT2113868	hsa-miR-4512	CLIP-seq
MIRT2113872	hsa-miR-4727-3p	CLIP-seq
MIRT2113881	hsa-miR-539	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IMP	20028982
GO:0000785	Component	Chromatin	ISA
GO:0000976	Function	Transcription cis-regulatory region binding	IDA	26525805
GO:0000976	Function	Transcription cis-regulatory region binding	IEA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IEA
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001217	Function	DNA-binding transcription repressor activity	IEA
GO:0001217	Function	DNA-binding transcription repressor activity	ISS
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IMP	20028982
GO:0003677	Function	DNA binding	IDA	10871192
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	TAS	10198172
GO:0005515	Function	Protein binding	IPI	17218525, 20028982, 21988832, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	10871192
GO:0005737	Component	Cytoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	ISS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0009653	Process	Anatomical structure morphogenesis	TAS	10198172
GO:0021529	Process	Spinal cord oligodendrocyte cell differentiation	IEA
GO:0021529	Process	Spinal cord oligodendrocyte cell differentiation	ISS
GO:0030154	Process	Cell differentiation	IEA
GO:0042492	Process	Gamma-delta T cell differentiation	IEA
GO:0042492	Process	Gamma-delta T cell differentiation	ISS
GO:0042802	Function	Identical protein binding	IPI	10871192
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0043565	Function	Sequence-specific DNA binding	ISS
GO:0045165	Process	Cell fate commitment	IBA
GO:0045586	Process	Regulation of gamma-delta T cell differentiation	IEA
GO:0045588	Process	Positive regulation of gamma-delta T cell differentiation	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IMP	20028982
GO:0090090	Process	Negative regulation of canonical Wnt signaling pathway	IMP	20028982
GO:0090336	Process	Positive regulation of brown fat cell differentiation	IEA
GO:0090336	Process	Positive regulation of brown fat cell differentiation	ISS

Other IDs

• MIM: 604748
• HGNC: 11192
• e!Ensembl: ENSG00000143842

Protein

• UniProt ID: Q9UN79
• Protein name: Transcription factor SOX-13 (Islet cell antigen 12) (SRY (Sex determining region Y)-box 13) (Type 1 diabetes autoantigen ICA12)
• Protein function: Transcription factor that binds to DNA at the consensus sequence 5'-AACAAT-3' (PubMed:10871192). Binds to the proximal promoter region of the myelin protein MPZ gene, and may thereby be involved in the differentiation of oligodendroglia in the d
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00505	HMG_box	424 → 492	HMG (high mobility group) box	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in exocrine cells and islets of Langerhans in the pancreas (at protein level) (PubMed:10871192). Expressed in the pancreas, placenta, kidney, brain, heart, lung, and liver (PubMed:10871192, PubMed:20028982). Expressed in adip
• Sequence:

  MSMRSPISAQLALDGVGTMVNCTIKSEEKKEPCHEAPQGSATAAEPQPGDPARASQDSAD
  PQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFNRNLKEVVPAIEKLLS
  SDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAML
  FEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLP
  VTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPK
  APELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPPSLPLGFLGEGDAVTKAIQDARQL
  LHSHSGALDGSPNTPFRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRN
  SSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARL
  SRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMS
  SSDVLYPRAAGMPLAQPLVEHYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSVADGEMYR
  YSEDEDSEGEEKSDGELVVLTD

• Sequence length: 622

Pathways

Reactome:

Deactivation of the beta-catenin transactivating complex