Gene Gene information from NCBI Gene database.
Entrez ID 9559
Gene name VPS26 retromer complex component A
Gene symbol VPS26A
Synonyms (NCBI Gene)
HB58Hbeta58PEP8AVPS26
Chromosome 10
Chromosome location 10q22.1
Summary This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. Th
miRNA miRNA information provided by mirtarbase database.
444
miRTarBase ID miRNA Experiments Reference
MIRT004448 hsa-miR-373-3p Microarray 15685193
MIRT004448 hsa-miR-373-3p Microarray 15685193
MIRT025885 hsa-miR-7-5p Microarray 17612493
MIRT025885 hsa-miR-7-5p Microarray 19073608
MIRT031005 hsa-miR-21-5p Microarray 18591254
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 11102511, 15078903, 16732284, 17891154, 19619496, 21725319, 24152121, 24747528, 24980502, 26496610, 27385586, 28514442, 28892079, 32296183, 32814053, 33961781, 35271311, 37172566
GO:0005737 Component Cytoplasm IEA
GO:0005764 Component Lysosome IDA
GO:0005768 Component Endosome IBA
GO:0005768 Component Endosome IDA 20682791
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
605506 12711 ENSG00000122958
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75436
Protein name Vacuolar protein sorting-associated protein 26A (Vesicle protein sorting 26A) (hVPS26)
Protein function Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins
PDB 2FAU , 5F0J , 5F0L , 5F0M , 5F0P , 7BLO
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03643 Vps26 8 283 Vacuolar protein sorting-associated protein 26 Family
Sequence
Sequence length 327
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Endocytosis   WNT ligand biogenesis and trafficking