EI24 (EI24 autophagy associated transmembrane protein)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9538 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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EI24 autophagy associated transmembrane protein |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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EI24 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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EPG4, PIG8, TP53I8 |
Chromosome
Chromosome number
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11 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11q24.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | O14681 | ||||||||||
Protein name | Etoposide-induced protein 2.4 homolog (p53-induced gene 8 protein) | ||||||||||
Protein function | Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity). | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 340 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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