BAG5 (BAG cochaperone 5)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9529 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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BAG cochaperone 5 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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BAG5 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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BAG-5, CMD2F |
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Chromosome
Chromosome number
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14 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q32.33 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroi |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||||||||||||
| UniProt ID | Q9UL15 | |||||||||||||||||||||||||
| Protein name | BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5) | |||||||||||||||||||||||||
| Protein function | Co-chaperone for HSP/HSP70 proteins. It functions as a nucleotide-exchange factor promoting the release of ADP from HSP70, thereby activating HSP70-mediated protein refolding (PubMed:20223214). Has an essential role in maintaining proteostasis a | |||||||||||||||||||||||||
| PDB | 2D9D , 3A8Y | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in the heart. {ECO:0000269|PubMed:35044787}. | |||||||||||||||||||||||||
| Sequence |
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| Sequence length | 447 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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