Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9415
Gene name Gene Name - the full gene name approved by the HGNC.	Fatty acid desaturase 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	FADS2
Synonyms (NCBI Gene) Gene synonyms aliases	D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11q12.2
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family mem

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miRTarBase ID	miRNA	Experiments	Reference
MIRT001634	hsa-let-7b-5p	pSILAC	18668040
MIRT017360	hsa-miR-335-5p	Microarray	18185580
MIRT029144	hsa-miR-26b-5p	Microarray	19088304
MIRT001634	hsa-let-7b-5p	Proteomics;Other	18668040
MIRT001634	hsa-let-7b-5p	CLASH	23622248
MIRT042871	hsa-miR-324-3p	CLASH	23622248
MIRT042511	hsa-miR-423-3p	CLASH	23622248
MIRT041155	hsa-miR-500a-3p	CLASH	23622248
MIRT040802	hsa-miR-18a-3p	CLASH	23622248
MIRT440695	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440695	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT975057	hsa-miR-1204	CLIP-seq
MIRT975058	hsa-miR-125a-5p	CLIP-seq
MIRT975059	hsa-miR-125b	CLIP-seq
MIRT975060	hsa-miR-1291	CLIP-seq
MIRT975061	hsa-miR-1470	CLIP-seq
MIRT975062	hsa-miR-3150b-3p	CLIP-seq
MIRT975063	hsa-miR-3173-5p	CLIP-seq
MIRT975064	hsa-miR-3611	CLIP-seq
MIRT975065	hsa-miR-3614-5p	CLIP-seq
MIRT975066	hsa-miR-4252	CLIP-seq
MIRT975067	hsa-miR-4319	CLIP-seq
MIRT975068	hsa-miR-4428	CLIP-seq
MIRT975069	hsa-miR-4469	CLIP-seq
MIRT975070	hsa-miR-4667-3p	CLIP-seq
MIRT975071	hsa-miR-4701-5p	CLIP-seq
MIRT975072	hsa-miR-4709-3p	CLIP-seq
MIRT975073	hsa-miR-4732-3p	CLIP-seq
MIRT975074	hsa-miR-4784	CLIP-seq
MIRT975075	hsa-miR-576-3p	CLIP-seq
MIRT975076	hsa-miR-588	CLIP-seq
MIRT975077	hsa-miR-670	CLIP-seq
MIRT1548467	hsa-miR-3945	CLIP-seq
MIRT1548468	hsa-miR-4706	CLIP-seq
MIRT1548469	hsa-miR-4734	CLIP-seq
MIRT1548470	hsa-miR-4749-5p	CLIP-seq
MIRT1548471	hsa-miR-4787-5p	CLIP-seq
MIRT1548472	hsa-miR-744	CLIP-seq
MIRT1556333	hsa-miR-4728-5p	CLIP-seq
MIRT1548471	hsa-miR-4787-5p	CLIP-seq
MIRT975061	hsa-miR-1470	CLIP-seq
MIRT1988902	hsa-miR-3064-5p	CLIP-seq
MIRT1988903	hsa-miR-3175	CLIP-seq
MIRT1988904	hsa-miR-4492	CLIP-seq
MIRT1988905	hsa-miR-4498	CLIP-seq
MIRT975070	hsa-miR-4667-3p	CLIP-seq
MIRT1988906	hsa-miR-762	CLIP-seq
MIRT2223294	hsa-let-7a	CLIP-seq
MIRT2223295	hsa-let-7b	CLIP-seq
MIRT2223296	hsa-let-7c	CLIP-seq
MIRT2223297	hsa-let-7d	CLIP-seq
MIRT2223298	hsa-let-7e	CLIP-seq
MIRT2223299	hsa-let-7f	CLIP-seq
MIRT2223300	hsa-let-7g	CLIP-seq
MIRT2223301	hsa-let-7i	CLIP-seq
MIRT2223302	hsa-miR-101	CLIP-seq
MIRT2223303	hsa-miR-1197	CLIP-seq
MIRT975057	hsa-miR-1204	CLIP-seq
MIRT2223304	hsa-miR-1205	CLIP-seq
MIRT2223305	hsa-miR-1224-3p	CLIP-seq
MIRT2223306	hsa-miR-1245	CLIP-seq
MIRT975058	hsa-miR-125a-5p	CLIP-seq
MIRT975059	hsa-miR-125b	CLIP-seq
MIRT2223307	hsa-miR-1270	CLIP-seq
MIRT2223308	hsa-miR-1273f	CLIP-seq
MIRT2223309	hsa-miR-1286	CLIP-seq
MIRT2223310	hsa-miR-1298	CLIP-seq
MIRT2223311	hsa-miR-1324	CLIP-seq
MIRT2223312	hsa-miR-133a	CLIP-seq
MIRT2223313	hsa-miR-133b	CLIP-seq
MIRT2223314	hsa-miR-144	CLIP-seq
MIRT975061	hsa-miR-1470	CLIP-seq
MIRT2223315	hsa-miR-151-3p	CLIP-seq
MIRT2223316	hsa-miR-1587	CLIP-seq
MIRT2223317	hsa-miR-1827	CLIP-seq
MIRT2223318	hsa-miR-1915	CLIP-seq
MIRT2223319	hsa-miR-202	CLIP-seq
MIRT2223320	hsa-miR-219-5p	CLIP-seq
MIRT1988902	hsa-miR-3064-5p	CLIP-seq
MIRT2223321	hsa-miR-3065-3p	CLIP-seq
MIRT2223322	hsa-miR-3115	CLIP-seq
MIRT2223323	hsa-miR-3126-5p	CLIP-seq
MIRT2223324	hsa-miR-3127-5p	CLIP-seq
MIRT2223325	hsa-miR-3150a-3p	CLIP-seq
MIRT2223326	hsa-miR-3154	CLIP-seq
MIRT2223327	hsa-miR-3155	CLIP-seq
MIRT2223328	hsa-miR-3155b	CLIP-seq
MIRT975063	hsa-miR-3173-5p	CLIP-seq
MIRT1988903	hsa-miR-3175	CLIP-seq
MIRT2223329	hsa-miR-3179	CLIP-seq
MIRT2223330	hsa-miR-3183	CLIP-seq
MIRT2223331	hsa-miR-3185	CLIP-seq
MIRT2223332	hsa-miR-3189-3p	CLIP-seq
MIRT2223333	hsa-miR-3192	CLIP-seq
MIRT2223334	hsa-miR-3194-5p	CLIP-seq
MIRT2223335	hsa-miR-323-3p	CLIP-seq
MIRT2223336	hsa-miR-330-3p	CLIP-seq
MIRT2223337	hsa-miR-3612	CLIP-seq
MIRT975065	hsa-miR-3614-5p	CLIP-seq
MIRT2223338	hsa-miR-3620	CLIP-seq
MIRT2223339	hsa-miR-3652	CLIP-seq
MIRT2223340	hsa-miR-3660	CLIP-seq
MIRT2223341	hsa-miR-3664-3p	CLIP-seq
MIRT2223342	hsa-miR-3672	CLIP-seq
MIRT2223343	hsa-miR-3689a-3p	CLIP-seq
MIRT2223344	hsa-miR-3689c	CLIP-seq
MIRT2223345	hsa-miR-3690	CLIP-seq
MIRT2223346	hsa-miR-3714	CLIP-seq
MIRT2223347	hsa-miR-3918	CLIP-seq
MIRT2223348	hsa-miR-3922-5p	CLIP-seq
MIRT2223349	hsa-miR-3943	CLIP-seq
MIRT1548467	hsa-miR-3945	CLIP-seq
MIRT2223350	hsa-miR-3974	CLIP-seq
MIRT2223351	hsa-miR-4266	CLIP-seq
MIRT2223352	hsa-miR-4268	CLIP-seq
MIRT2223353	hsa-miR-4281	CLIP-seq
MIRT2223354	hsa-miR-4290	CLIP-seq
MIRT2223355	hsa-miR-4313	CLIP-seq
MIRT975067	hsa-miR-4319	CLIP-seq
MIRT2223356	hsa-miR-432	CLIP-seq
MIRT2223357	hsa-miR-4329	CLIP-seq
MIRT2223358	hsa-miR-4419a	CLIP-seq
MIRT2223359	hsa-miR-4430	CLIP-seq
MIRT2223360	hsa-miR-4434	CLIP-seq
MIRT2223361	hsa-miR-4435	CLIP-seq
MIRT2223362	hsa-miR-4436a	CLIP-seq
MIRT2223363	hsa-miR-4436b-3p	CLIP-seq
MIRT2223364	hsa-miR-4438	CLIP-seq
MIRT2223365	hsa-miR-4446-3p	CLIP-seq
MIRT2223366	hsa-miR-4448	CLIP-seq
MIRT2223367	hsa-miR-4457	CLIP-seq
MIRT2223368	hsa-miR-4458	CLIP-seq
MIRT2223369	hsa-miR-4459	CLIP-seq
MIRT2223370	hsa-miR-4463	CLIP-seq
MIRT2223371	hsa-miR-4464	CLIP-seq
MIRT975069	hsa-miR-4469	CLIP-seq
MIRT2223372	hsa-miR-4489	CLIP-seq
MIRT1988904	hsa-miR-4492	CLIP-seq
MIRT1988905	hsa-miR-4498	CLIP-seq
MIRT2223373	hsa-miR-4499	CLIP-seq
MIRT2223374	hsa-miR-4500	CLIP-seq
MIRT2223375	hsa-miR-4505	CLIP-seq
MIRT2223376	hsa-miR-4510	CLIP-seq
MIRT2223377	hsa-miR-4516	CLIP-seq
MIRT2223378	hsa-miR-4526	CLIP-seq
MIRT2223379	hsa-miR-4531	CLIP-seq
MIRT2223380	hsa-miR-4535	CLIP-seq
MIRT2223381	hsa-miR-4632	CLIP-seq
MIRT2223382	hsa-miR-4645-3p	CLIP-seq
MIRT2223383	hsa-miR-4656	CLIP-seq
MIRT2223384	hsa-miR-4660	CLIP-seq
MIRT2223385	hsa-miR-4661-3p	CLIP-seq
MIRT2223386	hsa-miR-4663	CLIP-seq
MIRT975070	hsa-miR-4667-3p	CLIP-seq
MIRT2223387	hsa-miR-4674	CLIP-seq
MIRT2223388	hsa-miR-4675	CLIP-seq
MIRT2223389	hsa-miR-4693-3p	CLIP-seq
MIRT2223390	hsa-miR-4695-5p	CLIP-seq
MIRT975071	hsa-miR-4701-5p	CLIP-seq
MIRT1548468	hsa-miR-4706	CLIP-seq
MIRT2223391	hsa-miR-4708-3p	CLIP-seq
MIRT2223392	hsa-miR-4721	CLIP-seq
MIRT2223393	hsa-miR-4722-5p	CLIP-seq
MIRT2223394	hsa-miR-4723-3p	CLIP-seq
MIRT2223395	hsa-miR-4726-3p	CLIP-seq
MIRT2223396	hsa-miR-4727-5p	CLIP-seq
MIRT1556333	hsa-miR-4728-5p	CLIP-seq
MIRT975073	hsa-miR-4732-3p	CLIP-seq
MIRT1548469	hsa-miR-4734	CLIP-seq
MIRT2223397	hsa-miR-4736	CLIP-seq
MIRT2223398	hsa-miR-4740-3p	CLIP-seq
MIRT2223399	hsa-miR-4741	CLIP-seq
MIRT2223400	hsa-miR-4748	CLIP-seq
MIRT2223401	hsa-miR-4749-3p	CLIP-seq
MIRT1548470	hsa-miR-4749-5p	CLIP-seq
MIRT2223402	hsa-miR-4753-5p	CLIP-seq
MIRT2223403	hsa-miR-4768-3p	CLIP-seq
MIRT2223404	hsa-miR-4772-3p	CLIP-seq
MIRT2223405	hsa-miR-4776-5p	CLIP-seq
MIRT2223406	hsa-miR-4779	CLIP-seq
MIRT2223407	hsa-miR-4782-3p	CLIP-seq
MIRT2223408	hsa-miR-4783-3p	CLIP-seq
MIRT1548471	hsa-miR-4787-5p	CLIP-seq
MIRT2223409	hsa-miR-484	CLIP-seq
MIRT2223410	hsa-miR-488	CLIP-seq
MIRT2223411	hsa-miR-492	CLIP-seq
MIRT2223412	hsa-miR-495	CLIP-seq
MIRT2223413	hsa-miR-513a-5p	CLIP-seq
MIRT2223414	hsa-miR-513b	CLIP-seq
MIRT2223415	hsa-miR-515-3p	CLIP-seq
MIRT2223416	hsa-miR-519e	CLIP-seq
MIRT2223417	hsa-miR-544b	CLIP-seq
MIRT2223418	hsa-miR-548an	CLIP-seq
MIRT2223419	hsa-miR-548b-3p	CLIP-seq
MIRT2223420	hsa-miR-558	CLIP-seq
MIRT975076	hsa-miR-588	CLIP-seq
MIRT2223421	hsa-miR-617	CLIP-seq
MIRT2223422	hsa-miR-620	CLIP-seq
MIRT2223423	hsa-miR-634	CLIP-seq
MIRT2223424	hsa-miR-642a	CLIP-seq
MIRT2223425	hsa-miR-646	CLIP-seq
MIRT2223426	hsa-miR-647	CLIP-seq
MIRT2223427	hsa-miR-650	CLIP-seq
MIRT2223428	hsa-miR-657	CLIP-seq
MIRT975077	hsa-miR-670	CLIP-seq
MIRT2223429	hsa-miR-7	CLIP-seq
MIRT1548472	hsa-miR-744	CLIP-seq
MIRT1988906	hsa-miR-762	CLIP-seq
MIRT2223430	hsa-miR-766	CLIP-seq
MIRT2223431	hsa-miR-767-3p	CLIP-seq
MIRT2223432	hsa-miR-769-5p	CLIP-seq
MIRT2223433	hsa-miR-885-3p	CLIP-seq
MIRT2223434	hsa-miR-9	CLIP-seq
MIRT2223435	hsa-miR-939	CLIP-seq
MIRT2223436	hsa-miR-942	CLIP-seq
MIRT2223437	hsa-miR-98	CLIP-seq
MIRT2223302	hsa-miR-101	CLIP-seq
MIRT2223310	hsa-miR-1298	CLIP-seq
MIRT2223314	hsa-miR-144	CLIP-seq
MIRT1548467	hsa-miR-3945	CLIP-seq
MIRT1548468	hsa-miR-4706	CLIP-seq
MIRT2223396	hsa-miR-4727-5p	CLIP-seq
MIRT1548469	hsa-miR-4734	CLIP-seq
MIRT1548470	hsa-miR-4749-5p	CLIP-seq
MIRT1548471	hsa-miR-4787-5p	CLIP-seq
MIRT1548472	hsa-miR-744	CLIP-seq
MIRT2223294	hsa-let-7a	CLIP-seq
MIRT2223295	hsa-let-7b	CLIP-seq
MIRT2223296	hsa-let-7c	CLIP-seq
MIRT2223297	hsa-let-7d	CLIP-seq
MIRT2223298	hsa-let-7e	CLIP-seq
MIRT2223299	hsa-let-7f	CLIP-seq
MIRT2223300	hsa-let-7g	CLIP-seq
MIRT2223301	hsa-let-7i	CLIP-seq
MIRT2527250	hsa-miR-1184	CLIP-seq
MIRT2223303	hsa-miR-1197	CLIP-seq
MIRT2223304	hsa-miR-1205	CLIP-seq
MIRT2223305	hsa-miR-1224-3p	CLIP-seq
MIRT2527251	hsa-miR-1247	CLIP-seq
MIRT2223308	hsa-miR-1273f	CLIP-seq
MIRT975061	hsa-miR-1470	CLIP-seq
MIRT2527252	hsa-miR-1825	CLIP-seq
MIRT2223317	hsa-miR-1827	CLIP-seq
MIRT2527253	hsa-miR-1909	CLIP-seq
MIRT2223318	hsa-miR-1915	CLIP-seq
MIRT2527254	hsa-miR-1972	CLIP-seq
MIRT2527255	hsa-miR-1976	CLIP-seq
MIRT2527256	hsa-miR-199a-5p	CLIP-seq
MIRT2527257	hsa-miR-199b-5p	CLIP-seq
MIRT2527258	hsa-miR-2909	CLIP-seq
MIRT2223321	hsa-miR-3065-3p	CLIP-seq
MIRT2223325	hsa-miR-3150a-3p	CLIP-seq
MIRT2223326	hsa-miR-3154	CLIP-seq
MIRT975063	hsa-miR-3173-5p	CLIP-seq
MIRT1988903	hsa-miR-3175	CLIP-seq
MIRT2223329	hsa-miR-3179	CLIP-seq
MIRT2223330	hsa-miR-3183	CLIP-seq
MIRT2223331	hsa-miR-3185	CLIP-seq
MIRT2223332	hsa-miR-3189-3p	CLIP-seq
MIRT2527259	hsa-miR-324-5p	CLIP-seq
MIRT2527260	hsa-miR-331-3p	CLIP-seq
MIRT975065	hsa-miR-3614-5p	CLIP-seq
MIRT2527261	hsa-miR-361-5p	CLIP-seq
MIRT2223338	hsa-miR-3620	CLIP-seq
MIRT2527262	hsa-miR-3663-5p	CLIP-seq
MIRT2223341	hsa-miR-3664-3p	CLIP-seq
MIRT2527263	hsa-miR-3689d	CLIP-seq
MIRT2223345	hsa-miR-3690	CLIP-seq
MIRT2527264	hsa-miR-371b-3p	CLIP-seq
MIRT2223347	hsa-miR-3918	CLIP-seq
MIRT2223348	hsa-miR-3922-5p	CLIP-seq
MIRT2527265	hsa-miR-3925-3p	CLIP-seq
MIRT2527266	hsa-miR-3926	CLIP-seq
MIRT2223349	hsa-miR-3943	CLIP-seq
MIRT2527267	hsa-miR-4254	CLIP-seq
MIRT2527268	hsa-miR-4267	CLIP-seq
MIRT2223352	hsa-miR-4268	CLIP-seq
MIRT2527269	hsa-miR-4278	CLIP-seq
MIRT2527270	hsa-miR-4279	CLIP-seq
MIRT2223354	hsa-miR-4290	CLIP-seq
MIRT2527271	hsa-miR-4292	CLIP-seq
MIRT2223355	hsa-miR-4313	CLIP-seq
MIRT2223361	hsa-miR-4435	CLIP-seq
MIRT2223363	hsa-miR-4436b-3p	CLIP-seq
MIRT2223365	hsa-miR-4446-3p	CLIP-seq
MIRT2223366	hsa-miR-4448	CLIP-seq
MIRT2223367	hsa-miR-4457	CLIP-seq
MIRT2223368	hsa-miR-4458	CLIP-seq
MIRT975069	hsa-miR-4469	CLIP-seq
MIRT2223372	hsa-miR-4489	CLIP-seq
MIRT1988904	hsa-miR-4492	CLIP-seq
MIRT1988905	hsa-miR-4498	CLIP-seq
MIRT2223374	hsa-miR-4500	CLIP-seq
MIRT2223375	hsa-miR-4505	CLIP-seq
MIRT2223381	hsa-miR-4632	CLIP-seq
MIRT2223384	hsa-miR-4660	CLIP-seq
MIRT2223385	hsa-miR-4661-3p	CLIP-seq
MIRT975070	hsa-miR-4667-3p	CLIP-seq
MIRT2527272	hsa-miR-4688	CLIP-seq
MIRT2223389	hsa-miR-4693-3p	CLIP-seq
MIRT975071	hsa-miR-4701-5p	CLIP-seq
MIRT2223392	hsa-miR-4721	CLIP-seq
MIRT2223394	hsa-miR-4723-3p	CLIP-seq
MIRT2223395	hsa-miR-4726-3p	CLIP-seq
MIRT1556333	hsa-miR-4728-5p	CLIP-seq
MIRT2223398	hsa-miR-4740-3p	CLIP-seq
MIRT2223408	hsa-miR-4783-3p	CLIP-seq
MIRT2527273	hsa-miR-4793-5p	CLIP-seq
MIRT2527274	hsa-miR-486-3p	CLIP-seq
MIRT2223413	hsa-miR-513a-5p	CLIP-seq
MIRT2223414	hsa-miR-513b	CLIP-seq
MIRT975076	hsa-miR-588	CLIP-seq
MIRT2527275	hsa-miR-596	CLIP-seq
MIRT2223421	hsa-miR-617	CLIP-seq
MIRT2223423	hsa-miR-634	CLIP-seq
MIRT2223424	hsa-miR-642a	CLIP-seq
MIRT2223425	hsa-miR-646	CLIP-seq
MIRT2527276	hsa-miR-662	CLIP-seq
MIRT2223429	hsa-miR-7	CLIP-seq
MIRT1988906	hsa-miR-762	CLIP-seq
MIRT2223430	hsa-miR-766	CLIP-seq
MIRT2223431	hsa-miR-767-3p	CLIP-seq
MIRT2223432	hsa-miR-769-5p	CLIP-seq
MIRT2223433	hsa-miR-885-3p	CLIP-seq
MIRT2223435	hsa-miR-939	CLIP-seq
MIRT2223436	hsa-miR-942	CLIP-seq
MIRT2223437	hsa-miR-98	CLIP-seq
MIRT2223294	hsa-let-7a	CLIP-seq
MIRT2223295	hsa-let-7b	CLIP-seq
MIRT2223296	hsa-let-7c	CLIP-seq
MIRT2223297	hsa-let-7d	CLIP-seq
MIRT2223298	hsa-let-7e	CLIP-seq
MIRT2223299	hsa-let-7f	CLIP-seq
MIRT2223300	hsa-let-7g	CLIP-seq
MIRT2223301	hsa-let-7i	CLIP-seq
MIRT2223302	hsa-miR-101	CLIP-seq
MIRT2527250	hsa-miR-1184	CLIP-seq
MIRT2223303	hsa-miR-1197	CLIP-seq
MIRT2223304	hsa-miR-1205	CLIP-seq
MIRT2223305	hsa-miR-1224-3p	CLIP-seq
MIRT2527251	hsa-miR-1247	CLIP-seq
MIRT2223308	hsa-miR-1273f	CLIP-seq
MIRT2223310	hsa-miR-1298	CLIP-seq
MIRT2223314	hsa-miR-144	CLIP-seq
MIRT975061	hsa-miR-1470	CLIP-seq
MIRT2527252	hsa-miR-1825	CLIP-seq
MIRT2223317	hsa-miR-1827	CLIP-seq
MIRT2527253	hsa-miR-1909	CLIP-seq
MIRT2223318	hsa-miR-1915	CLIP-seq
MIRT2527254	hsa-miR-1972	CLIP-seq
MIRT2527255	hsa-miR-1976	CLIP-seq
MIRT2527256	hsa-miR-199a-5p	CLIP-seq
MIRT2527257	hsa-miR-199b-5p	CLIP-seq
MIRT2527258	hsa-miR-2909	CLIP-seq
MIRT2223321	hsa-miR-3065-3p	CLIP-seq
MIRT2223322	hsa-miR-3115	CLIP-seq
MIRT2223325	hsa-miR-3150a-3p	CLIP-seq
MIRT2223326	hsa-miR-3154	CLIP-seq
MIRT975063	hsa-miR-3173-5p	CLIP-seq
MIRT1988903	hsa-miR-3175	CLIP-seq
MIRT2223329	hsa-miR-3179	CLIP-seq
MIRT2223330	hsa-miR-3183	CLIP-seq
MIRT2223331	hsa-miR-3185	CLIP-seq
MIRT2223332	hsa-miR-3189-3p	CLIP-seq
MIRT2223335	hsa-miR-323-3p	CLIP-seq
MIRT2527259	hsa-miR-324-5p	CLIP-seq
MIRT2527260	hsa-miR-331-3p	CLIP-seq
MIRT975065	hsa-miR-3614-5p	CLIP-seq
MIRT2527261	hsa-miR-361-5p	CLIP-seq
MIRT2223338	hsa-miR-3620	CLIP-seq
MIRT2527262	hsa-miR-3663-5p	CLIP-seq
MIRT2223341	hsa-miR-3664-3p	CLIP-seq
MIRT2527263	hsa-miR-3689d	CLIP-seq
MIRT2223345	hsa-miR-3690	CLIP-seq
MIRT2527264	hsa-miR-371b-3p	CLIP-seq
MIRT2223347	hsa-miR-3918	CLIP-seq
MIRT2223348	hsa-miR-3922-5p	CLIP-seq
MIRT2527265	hsa-miR-3925-3p	CLIP-seq
MIRT2527266	hsa-miR-3926	CLIP-seq
MIRT2223349	hsa-miR-3943	CLIP-seq
MIRT1548467	hsa-miR-3945	CLIP-seq
MIRT2527267	hsa-miR-4254	CLIP-seq
MIRT2527268	hsa-miR-4267	CLIP-seq
MIRT2223352	hsa-miR-4268	CLIP-seq
MIRT2527269	hsa-miR-4278	CLIP-seq
MIRT2527270	hsa-miR-4279	CLIP-seq
MIRT2223354	hsa-miR-4290	CLIP-seq
MIRT2527271	hsa-miR-4292	CLIP-seq
MIRT2223355	hsa-miR-4313	CLIP-seq
MIRT2223365	hsa-miR-4446-3p	CLIP-seq
MIRT2223366	hsa-miR-4448	CLIP-seq
MIRT2223367	hsa-miR-4457	CLIP-seq
MIRT2223368	hsa-miR-4458	CLIP-seq
MIRT975069	hsa-miR-4469	CLIP-seq
MIRT2223372	hsa-miR-4489	CLIP-seq
MIRT1988904	hsa-miR-4492	CLIP-seq
MIRT1988905	hsa-miR-4498	CLIP-seq
MIRT2223374	hsa-miR-4500	CLIP-seq
MIRT2223375	hsa-miR-4505	CLIP-seq
MIRT2223381	hsa-miR-4632	CLIP-seq
MIRT2223384	hsa-miR-4660	CLIP-seq
MIRT2223385	hsa-miR-4661-3p	CLIP-seq
MIRT975070	hsa-miR-4667-3p	CLIP-seq
MIRT2527272	hsa-miR-4688	CLIP-seq
MIRT2223389	hsa-miR-4693-3p	CLIP-seq
MIRT975071	hsa-miR-4701-5p	CLIP-seq
MIRT1548468	hsa-miR-4706	CLIP-seq
MIRT2223392	hsa-miR-4721	CLIP-seq
MIRT2223394	hsa-miR-4723-3p	CLIP-seq
MIRT2223395	hsa-miR-4726-3p	CLIP-seq
MIRT2223396	hsa-miR-4727-5p	CLIP-seq
MIRT1556333	hsa-miR-4728-5p	CLIP-seq
MIRT1548469	hsa-miR-4734	CLIP-seq
MIRT2223398	hsa-miR-4740-3p	CLIP-seq
MIRT1548470	hsa-miR-4749-5p	CLIP-seq
MIRT2223408	hsa-miR-4783-3p	CLIP-seq
MIRT1548471	hsa-miR-4787-5p	CLIP-seq
MIRT2527273	hsa-miR-4793-5p	CLIP-seq
MIRT2527274	hsa-miR-486-3p	CLIP-seq
MIRT2223413	hsa-miR-513a-5p	CLIP-seq
MIRT2223414	hsa-miR-513b	CLIP-seq
MIRT975076	hsa-miR-588	CLIP-seq
MIRT2527275	hsa-miR-596	CLIP-seq
MIRT2223421	hsa-miR-617	CLIP-seq
MIRT2223423	hsa-miR-634	CLIP-seq
MIRT2223424	hsa-miR-642a	CLIP-seq
MIRT2223425	hsa-miR-646	CLIP-seq
MIRT2527276	hsa-miR-662	CLIP-seq
MIRT2223429	hsa-miR-7	CLIP-seq
MIRT1548472	hsa-miR-744	CLIP-seq
MIRT1988906	hsa-miR-762	CLIP-seq
MIRT2223430	hsa-miR-766	CLIP-seq
MIRT2223431	hsa-miR-767-3p	CLIP-seq
MIRT2223432	hsa-miR-769-5p	CLIP-seq
MIRT2223433	hsa-miR-885-3p	CLIP-seq
MIRT2223435	hsa-miR-939	CLIP-seq
MIRT2223436	hsa-miR-942	CLIP-seq
MIRT2223437	hsa-miR-98	CLIP-seq

Show/Hide all(30)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002538	Process	Arachidonate metabolite production involved in inflammatory response	IEA
GO:0004768	Function	Stearoyl-CoA 9-desaturase activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0005886	Component	Plasma membrane	TAS	9867867
GO:0006629	Process	Lipid metabolic process	IBA
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006631	Process	Fatty acid metabolic process	IEA
GO:0006633	Process	Fatty acid biosynthetic process	IEA
GO:0006636	Process	Unsaturated fatty acid biosynthetic process	IEA
GO:0006636	Process	Unsaturated fatty acid biosynthetic process	TAS	9867867
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IBA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	9867867
GO:0016213	Function	Acyl-CoA 6-desaturase activity	IEA
GO:0016213	Function	Acyl-CoA 6-desaturase activity	TAS
GO:0016215	Function	Acyl-CoA desaturase activity	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016717	Function	Oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	IBA
GO:0036109	Process	Alpha-linolenic acid metabolic process	IEA
GO:0036109	Process	Alpha-linolenic acid metabolic process	TAS
GO:0042759	Process	Long-chain fatty acid biosynthetic process	IEA
GO:0043651	Process	Linoleic acid metabolic process	IEA
GO:0043651	Process	Linoleic acid metabolic process	TAS
GO:1900409	Process	Positive regulation of cellular response to oxidative stress	IEA
GO:1901570	Process	Fatty acid derivative biosynthetic process	IEA

MIM	HGNC	e!Ensembl
606149	3575	ENSG00000134824

Protein

UniProt ID

O95864

Protein name

Acyl-CoA 6-desaturase (EC 1.14.19.3) (Delta(6) fatty acid desaturase) (D6D) (Delta(6) desaturase) (Delta-6 desaturase) (Fatty acid desaturase 2)

Protein function

Involved in the biosynthesis of highly unsaturated fatty acids (HUFA) from the essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3) precursors, acting as a fatty acyl-coenzyme A (CoA)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00173	Cyt-b5	22 → 95	Cytochrome b5-like Heme/Steroid binding domain	Domain
PF00487	FA_desaturase	156 → 418	Fatty acid desaturase	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in a wide array of tissues, highest expression is found in liver followed by brain, lung, heart, and retina. A lower level is found in breast tumor when compared with normal tissues; lowest levels were found in patients with

Sequence

MGKGGNQGEGAAEREVSVPTFSWEEIQKHNLRTDRWLVIDRKVYNITKWSIQHPGGQRVI
GHYAGEDATDAFRAFHPDLEFVGKFLKPLLIGELAPEEPSQDHGKNSKITEDFRALRKTA
EDMNLFKTNHVFFLLLLAHIIALESIAWFTVFYFGNGWIPTLITAFVLATSQAQAGWLQH
DYGHLSVYRKPKWNHLVHKFVIGHLKGASANWWNHRHFQHHAKPNIFHKDPDVNMLHVFV
LGEWQPIEYGKKKLKYLPYNHQHEYFFLIGPPLLIPMYFQYQIIMTMIVHKNWVDLAWAV
SYYIRFFITYIPFYGILGALLFLNFIRFLESHWFVWVTQMNHIVMEIDQEAYRDWFSSQL
TATCNVEQSFFNDWFSGHLNFQIEHHLFPTMPRHNLHKIAPLVKSLCAKHGIEYQEKPLL
RALLDIIRSLKKSGKLWLDAYLHK

Sequence length

444

Interactions

View interactions

	KEGG		Reactome
	alpha-Linolenic acid metabolism Biosynthesis of unsaturated fatty acids Metabolic pathways Fatty acid metabolism PPAR signaling pathway		Linoleic acid (LA) metabolism alpha-linolenic acid (ALA) metabolism

Show/Hide Unknown Diseases (19)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Acne	acne vulgaris	N/A	N/A	GWAS
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Aortic Valve Sclerosis	Aortic valve stenosis	N/A	N/A	GWAS
Asthma	Nonatopic asthma, Asthma in any disease, Asthma (adult onset), Asthma	N/A	N/A	GWAS
Bipolar Disorder	Bipolar disorder, Bipolar I disorder	N/A	N/A	GWAS
Cholelithiasis	Cholelithiasis	N/A	N/A	GWAS
Colorectal Cancer	Colorectal cancer	N/A	N/A	GWAS
Crohn Disease	Crohn's disease	N/A	N/A	GWAS
Dermatitis	Atopic dermatitis	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Gout	Gout	N/A	N/A	GWAS
Hypothyroidism	Hypothyroidism	N/A	N/A	GWAS
Inflammatory Bowel Disease	Inflammatory bowel disease	N/A	N/A	GWAS
Laryngeal Carcinoma	Laryngeal squamous cell carcinoma	N/A	N/A	GWAS
Lung adenocarcinoma	Lung adenocarcinoma	N/A	N/A	GWAS
Metabolic Syndrome	Serum omega-3 polyunsaturated fatty acid concentration in metabolic syndrome, Metabolic syndrome, Serum omega-6 to omega-3 polyunsaturated fatty acid ratio in metabolic syndrome, Serum docosahexaenoic fatty acid concentration in metabolic syndrome	N/A	N/A	GWAS
Rheumatoid arthritis	Rheumatoid arthritis	N/A	N/A	GWAS
Ulcerative colitis	Ulcerative colitis	N/A	N/A	GWAS
Vitiligo	Vitiligo	N/A	N/A	GWAS

Show/Hide Text Mining Associations (70)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenocarcinoma	Associate	35560527
Adenoma Islet Cell	Associate	24240437
Aortic Valve Stenosis	Associate	32186652
Arthritis Rheumatoid	Associate	29193869
Asthma	Associate	24934276
Autism Spectrum Disorder	Associate	30180836
Autism Spectrum Disorder	Inhibit	30180836
Bipolar Disorder	Associate	20615514, 28115744, 30531795
Breast Neoplasms	Associate	26656090, 37122728
Carcinoma Basal Cell	Associate	36496446
Carcinoma Renal Cell	Associate	33221754
Carcinoma Squamous Cell	Associate	36496446
Cardio Renal Syndrome	Associate	35773659
Cardiovascular Diseases	Associate	28253292, 35796550
Cerebral Infarction	Associate	26261632, 35796550, 36193932
Chronic Disease	Associate	29746616
Cleft Lip	Associate	36008388
Cognitive Dysfunction	Associate	27273350
Colorectal Neoplasms	Associate	28506205, 32486849, 35779418, 36696241, 40430008
Coronary Artery Disease	Associate	18842780, 23383292, 26261632, 27004414
Coronary Artery Disease	Stimulate	32731631
Coronary Disease	Associate	21347282
COVID 19	Associate	33530084
Crohn Disease	Associate	31956234
Dermatitis Atopic	Associate	24167612
Diabetes Mellitus	Associate	20980488, 24294133, 27322064, 27406814
Diabetes Mellitus Type 2	Associate	27004414, 27322064, 28555039, 32731631, 34162950, 34394238, 36412559
Diabetes Mellitus Type 2	Inhibit	29233142
Drug Related Side Effects and Adverse Reactions	Associate	26656090
Dyslipidemias	Associate	19060906, 26879377, 29746616
Eczema	Associate	20948998
Endometriosis	Associate	38012607
Erectile Dysfunction	Inhibit	29233142
Glioblastoma	Associate	32392704, 37158834
Heart Failure	Associate	31059043
Hypertension	Associate	27589269
Inflammation	Associate	26609056, 36430859, 37461045
Inflammatory Bowel Diseases	Associate	36430859
Insulin Resistance	Associate	26087292, 34394238, 36788508
Kidney Diseases	Associate	25329159
Lymphatic Metastasis	Stimulate	36696241
Macular Degeneration	Associate	24346170
Metabolic Diseases	Associate	28253292
Metabolic Syndrome	Associate	36496446, 38394918
Multiple Sclerosis	Inhibit	33063621
Multiple Sclerosis	Associate	33063621
Myocardial Infarction	Associate	17284757
Necrosis	Associate	32392704
Neoplasm Metastasis	Stimulate	36696241
Neoplasms	Associate	22140540, 32392704, 33567271
Neoplasms	Stimulate	36696241
Non alcoholic Fatty Liver Disease	Associate	30654845
Obesity	Associate	16908951, 24294133, 26609056, 27322064, 28598979, 30654845, 32584610, 33494132, 34611217, 35773659, 35779418, 36788508
Obesity Abdominal	Associate	28125662
Orofacial Cleft 1	Associate	36008388
Osteosarcoma	Inhibit	40593006
Overweight	Associate	32584610, 33494132
Pancreatic Neoplasms	Associate	24294133
Peripheral Arterial Disease	Associate	35796550
Pneumonia Lipid	Associate	36652541
Polycystic Ovary Syndrome	Associate	26879377
Pre Eclampsia	Associate	22949531
Status Asthmaticus	Stimulate	24934276
Stroke	Inhibit	36193932
Stroke	Associate	36193932
Urinary Bladder Neoplasms	Associate	34418989
Vascular System Injuries	Associate	18842780
Venous Thromboembolism	Associate	35796550
Ventricular Remodeling	Associate	31532795
Weight Loss	Associate	17823443, 26609056

FADS2 (fatty acid desaturase 2)