Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	94120
Gene name	Synaptotagmin like 3
Gene symbol	SYTL3
Synonyms (NCBI Gene)	SLP3
Chromosome	6
Chromosome location	6q25.3
Summary	The protein encoded by this gene belongs to a family of peripheral membrane proteins that play a role in vesicular trafficking. This protein binds phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different

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miRTarBase ID	miRNA	Experiments	Reference
MIRT516511	hsa-miR-302f	HITS-CLIP	23313552
MIRT693307	hsa-miR-890	HITS-CLIP	23313552
MIRT693306	hsa-miR-5690	HITS-CLIP	23313552
MIRT516510	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT516509	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT516508	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT516507	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT516506	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT516505	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT516504	hsa-miR-4505	HITS-CLIP	23313552
MIRT516503	hsa-miR-5787	HITS-CLIP	23313552
MIRT693305	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT693304	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693303	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693302	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693301	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693300	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT516502	hsa-miR-6721-5p	HITS-CLIP	23313552
MIRT516501	hsa-miR-486-3p	HITS-CLIP	23313552
MIRT516500	hsa-miR-449c-3p	HITS-CLIP	23313552
MIRT693299	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT693298	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT693297	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT693296	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT693295	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT693294	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT693293	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT693292	hsa-miR-3689c	HITS-CLIP	23313552
MIRT693291	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT693290	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT693289	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT516511	hsa-miR-302f	PAR-CLIP	23446348
MIRT516510	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT516509	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT516508	hsa-miR-485-5p	PAR-CLIP	23446348
MIRT516507	hsa-miR-6884-5p	PAR-CLIP	23446348
MIRT516506	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT516505	hsa-miR-4731-5p	PAR-CLIP	23446348
MIRT516504	hsa-miR-4505	PAR-CLIP	23446348
MIRT516503	hsa-miR-5787	PAR-CLIP	23446348
MIRT516502	hsa-miR-6721-5p	PAR-CLIP	23446348
MIRT516501	hsa-miR-486-3p	PAR-CLIP	23446348
MIRT516500	hsa-miR-449c-3p	PAR-CLIP	23446348
MIRT516511	hsa-miR-302f	HITS-CLIP	23313552
MIRT693307	hsa-miR-890	HITS-CLIP	23313552
MIRT693306	hsa-miR-5690	HITS-CLIP	23313552
MIRT516510	hsa-miR-4768-3p	HITS-CLIP	23313552
MIRT516509	hsa-miR-219b-3p	HITS-CLIP	23313552
MIRT516508	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT516507	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT516506	hsa-miR-4722-5p	HITS-CLIP	23313552
MIRT516505	hsa-miR-4731-5p	HITS-CLIP	23313552
MIRT516504	hsa-miR-4505	HITS-CLIP	23313552
MIRT516503	hsa-miR-5787	HITS-CLIP	23313552
MIRT693305	hsa-miR-7106-5p	HITS-CLIP	23313552
MIRT693304	hsa-miR-149-3p	HITS-CLIP	23313552
MIRT693303	hsa-miR-4728-5p	HITS-CLIP	23313552
MIRT693302	hsa-miR-6785-5p	HITS-CLIP	23313552
MIRT693301	hsa-miR-6883-5p	HITS-CLIP	23313552
MIRT693300	hsa-miR-6799-5p	HITS-CLIP	23313552
MIRT516502	hsa-miR-6721-5p	HITS-CLIP	23313552
MIRT516501	hsa-miR-486-3p	HITS-CLIP	23313552
MIRT516500	hsa-miR-449c-3p	HITS-CLIP	23313552
MIRT693299	hsa-miR-30c-1-3p	HITS-CLIP	23313552
MIRT693298	hsa-miR-30c-2-3p	HITS-CLIP	23313552
MIRT693297	hsa-miR-6788-5p	HITS-CLIP	23313552
MIRT693296	hsa-miR-1273h-5p	HITS-CLIP	23313552
MIRT693295	hsa-miR-30b-3p	HITS-CLIP	23313552
MIRT693294	hsa-miR-3689a-3p	HITS-CLIP	23313552
MIRT693293	hsa-miR-3689b-3p	HITS-CLIP	23313552
MIRT693292	hsa-miR-3689c	HITS-CLIP	23313552
MIRT693291	hsa-miR-6779-5p	HITS-CLIP	23313552
MIRT693290	hsa-miR-6780a-5p	HITS-CLIP	23313552
MIRT693289	hsa-miR-887-5p	HITS-CLIP	23313552
MIRT516511	hsa-miR-302f	PAR-CLIP	23446348
MIRT516510	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT516509	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT516508	hsa-miR-485-5p	PAR-CLIP	23446348
MIRT516507	hsa-miR-6884-5p	PAR-CLIP	23446348
MIRT516506	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT516505	hsa-miR-4731-5p	PAR-CLIP	23446348
MIRT516504	hsa-miR-4505	PAR-CLIP	23446348
MIRT516503	hsa-miR-5787	PAR-CLIP	23446348
MIRT516502	hsa-miR-6721-5p	PAR-CLIP	23446348
MIRT516501	hsa-miR-486-3p	PAR-CLIP	23446348
MIRT516500	hsa-miR-449c-3p	PAR-CLIP	23446348

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0005543	Function	Phospholipid binding	IEA
GO:0005544	Function	Calcium-dependent phospholipid binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0006886	Process	Intracellular protein transport	IEA
GO:0006887	Process	Exocytosis	IBA
GO:0006887	Process	Exocytosis	IEA
GO:0012505	Component	Endomembrane system	IEA
GO:0016020	Component	Membrane	IEA
GO:0031267	Function	Small GTPase binding	IEA
GO:0042043	Function	Neurexin family protein binding	IBA
GO:0042043	Function	Neurexin family protein binding	IEA
GO:0070382	Component	Exocytic vesicle	IBA

MIM	HGNC	e!Ensembl
620973	15587	ENSG00000164674

Q4VX76

Protein name

Synaptotagmin-like protein 3 (Exophilin-6)

Protein function

May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02318	FYVE_2	8 → 124	FYVE-type zinc finger	Family
PF00168	C2	321 → 433	C2 domain	Domain
PF00168	C2	480 → 585	C2 domain	Domain

Sequence

MAQEIDLSALKELEREAILQVLYRDQAVQNTEEERTRKLKTHLQHLRWKGAKNTDWEHKE
KCCARCQQVLGFLLHRGAVCRGCSHRVCAQCRVFLRGTHAWKCTVCFEDRNVKIKTGEWF
YEERAKKFPTGGKHETVGGQLLQSYQKLSKISVVPPTPPPVSESQCSRSPGRLQEFGQFR
GFNKSVENLFLSLATHVKKLSKSQNDMTSEKHLLATGPRQCVGQTERRSQSDTAVNVTTR
KVSAPDILKPLNQEDPKCSTNPILKQQNLPSSPAPSTIFSGGFRHGSLISIDSTCTEMGN
FDNANVTGEIEFAIHYCFKTHSLEICIKACKNLAYGEEKKKKCNPYVKTYLLPDRSSQGK
RKTGVQRNTVDPTFQETLKYQVAPAQLVTRQLQVSVWHLGTLARRVFLGEVIIPLATWDF
EDSTTQSFRWHPLRAKAEKYEDSVPQSNGELTVRAKLVLPSRPRKLQEAQEGTDQPSLHG
QLCLVVLGAKNLPVRPDGTLNSFVKGCLTLPDQQKLRLKSPVLRKQACPQWKHSFVFSGV
TPAQLRQSSLELTVWDQALFGMNDRLLGGTRLGSKGDTAVGGDACSLSKLQWQKVLSSPN
LWTDMTLVLH

Sequence length

610

Interactions

View interactions

SYTL3 (synaptotagmin like 3)