SFXN5 (sideroflexin 5)

Gene

• Entrez ID: 94097
• Gene name: Sideroflexin 5
• Gene symbol: SFXN5
• Synonyms (NCBI Gene): BBG-TCC, SLC56A5
• Chromosome: 2
• Chromosome location: 2p13.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020184	hsa-miR-130b-3p	Sequencing	20371350
MIRT028019	hsa-miR-93-5p	Sequencing	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	21572407
MIRT554362	hsa-miR-137	PAR-CLIP	21572407
MIRT554361	hsa-miR-605-5p	PAR-CLIP	21572407
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	21572407
MIRT554358	hsa-miR-4801	PAR-CLIP	21572407
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT554357	hsa-miR-186-3p	PAR-CLIP	21572407
MIRT554355	hsa-miR-3941	PAR-CLIP	21572407
MIRT554356	hsa-miR-4672	PAR-CLIP	21572407
MIRT554354	hsa-miR-466	PAR-CLIP	21572407
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	20371350
MIRT554362	hsa-miR-137	PAR-CLIP	20371350
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	20371350
MIRT554358	hsa-miR-4801	PAR-CLIP	20371350
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	20371350
MIRT554357	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT554355	hsa-miR-3941	PAR-CLIP	20371350
MIRT554356	hsa-miR-4672	PAR-CLIP	20371350
MIRT554354	hsa-miR-466	PAR-CLIP	20371350
MIRT554363	hsa-miR-496	PAR-CLIP	21572407
MIRT554362	hsa-miR-137	PAR-CLIP	21572407
MIRT554361	hsa-miR-605-5p	PAR-CLIP	21572407
MIRT554360	hsa-miR-4731-3p	PAR-CLIP	21572407
MIRT554358	hsa-miR-4801	PAR-CLIP	21572407
MIRT554359	hsa-miR-6504-3p	PAR-CLIP	21572407
MIRT554357	hsa-miR-186-3p	PAR-CLIP	21572407
MIRT554355	hsa-miR-3941	PAR-CLIP	21572407
MIRT554356	hsa-miR-4672	PAR-CLIP	21572407
MIRT554354	hsa-miR-466	PAR-CLIP	21572407
MIRT1342693	hsa-miR-1	CLIP-seq
MIRT1342694	hsa-miR-106a	CLIP-seq
MIRT1342695	hsa-miR-106b	CLIP-seq
MIRT1342696	hsa-miR-1184	CLIP-seq
MIRT1342697	hsa-miR-1205	CLIP-seq
MIRT1342698	hsa-miR-1224-5p	CLIP-seq
MIRT1342699	hsa-miR-1237	CLIP-seq
MIRT1342700	hsa-miR-1245b-5p	CLIP-seq
MIRT1342701	hsa-miR-125a-5p	CLIP-seq
MIRT1342702	hsa-miR-125b	CLIP-seq
MIRT1342703	hsa-miR-1273f	CLIP-seq
MIRT1342704	hsa-miR-127-5p	CLIP-seq
MIRT1342705	hsa-miR-1287	CLIP-seq
MIRT1342706	hsa-miR-1289	CLIP-seq
MIRT1342707	hsa-miR-1292	CLIP-seq
MIRT1342708	hsa-miR-1299	CLIP-seq
MIRT1342709	hsa-miR-1301	CLIP-seq
MIRT1342710	hsa-miR-142-5p	CLIP-seq
MIRT1342711	hsa-miR-15a	CLIP-seq
MIRT1342712	hsa-miR-15b	CLIP-seq
MIRT1342713	hsa-miR-16	CLIP-seq
MIRT1342714	hsa-miR-17	CLIP-seq
MIRT1342715	hsa-miR-195	CLIP-seq
MIRT1342716	hsa-miR-206	CLIP-seq
MIRT1342717	hsa-miR-20a	CLIP-seq
MIRT1342718	hsa-miR-20b	CLIP-seq
MIRT1342719	hsa-miR-218	CLIP-seq
MIRT1342720	hsa-miR-23a	CLIP-seq
MIRT1342721	hsa-miR-23b	CLIP-seq
MIRT1342722	hsa-miR-23c	CLIP-seq
MIRT1342723	hsa-miR-24	CLIP-seq
MIRT1342724	hsa-miR-2467-5p	CLIP-seq
MIRT1342725	hsa-miR-299-3p	CLIP-seq
MIRT1342726	hsa-miR-3135b	CLIP-seq
MIRT1342727	hsa-miR-3142	CLIP-seq
MIRT1342728	hsa-miR-3158-5p	CLIP-seq
MIRT1342729	hsa-miR-3179	CLIP-seq
MIRT1342730	hsa-miR-3188	CLIP-seq
MIRT1342731	hsa-miR-3198	CLIP-seq
MIRT1342732	hsa-miR-3201	CLIP-seq
MIRT1342733	hsa-miR-3609	CLIP-seq
MIRT1342734	hsa-miR-3613-3p	CLIP-seq
MIRT1342735	hsa-miR-3622a-3p	CLIP-seq
MIRT1342736	hsa-miR-3622b-3p	CLIP-seq
MIRT1342737	hsa-miR-3667-5p	CLIP-seq
MIRT1342738	hsa-miR-3673	CLIP-seq
MIRT1342739	hsa-miR-371b-5p	CLIP-seq
MIRT1342740	hsa-miR-377	CLIP-seq
MIRT1342741	hsa-miR-3922-5p	CLIP-seq
MIRT1342742	hsa-miR-3938	CLIP-seq
MIRT1342743	hsa-miR-3975	CLIP-seq
MIRT1342744	hsa-miR-424	CLIP-seq
MIRT1342745	hsa-miR-4252	CLIP-seq
MIRT1342746	hsa-miR-4265	CLIP-seq
MIRT1342747	hsa-miR-4274	CLIP-seq
MIRT1342748	hsa-miR-4284	CLIP-seq
MIRT1342749	hsa-miR-4292	CLIP-seq
MIRT1342750	hsa-miR-4294	CLIP-seq
MIRT1342751	hsa-miR-4296	CLIP-seq
MIRT1342752	hsa-miR-4300	CLIP-seq
MIRT1342753	hsa-miR-4308	CLIP-seq
MIRT1342754	hsa-miR-4309	CLIP-seq
MIRT1342755	hsa-miR-431	CLIP-seq
MIRT1342756	hsa-miR-4319	CLIP-seq
MIRT1342757	hsa-miR-4322	CLIP-seq
MIRT1342758	hsa-miR-4325	CLIP-seq
MIRT1342759	hsa-miR-4417	CLIP-seq
MIRT1342760	hsa-miR-4457	CLIP-seq
MIRT1342761	hsa-miR-4468	CLIP-seq
MIRT1342762	hsa-miR-4471	CLIP-seq
MIRT1342763	hsa-miR-4530	CLIP-seq
MIRT1342764	hsa-miR-4635	CLIP-seq
MIRT1342765	hsa-miR-4639-3p	CLIP-seq
MIRT1342766	hsa-miR-4640-5p	CLIP-seq
MIRT1342767	hsa-miR-4649-3p	CLIP-seq
MIRT1342768	hsa-miR-4654	CLIP-seq
MIRT1342769	hsa-miR-4660	CLIP-seq
MIRT1342770	hsa-miR-4663	CLIP-seq
MIRT1342771	hsa-miR-4676-5p	CLIP-seq
MIRT1342772	hsa-miR-4704-3p	CLIP-seq
MIRT1342773	hsa-miR-4706	CLIP-seq
MIRT1342774	hsa-miR-4708-3p	CLIP-seq
MIRT1342775	hsa-miR-4709-3p	CLIP-seq
MIRT1342776	hsa-miR-4716-3p	CLIP-seq
MIRT1342777	hsa-miR-4720-5p	CLIP-seq
MIRT1342778	hsa-miR-4726-5p	CLIP-seq
MIRT1342779	hsa-miR-4732-3p	CLIP-seq
MIRT1342780	hsa-miR-4749-5p	CLIP-seq
MIRT1342781	hsa-miR-4751	CLIP-seq
MIRT1342782	hsa-miR-4753-5p	CLIP-seq
MIRT1342783	hsa-miR-4755-3p	CLIP-seq
MIRT1342784	hsa-miR-4764-5p	CLIP-seq
MIRT1342785	hsa-miR-4769-5p	CLIP-seq
MIRT1342786	hsa-miR-4789-3p	CLIP-seq
MIRT1342787	hsa-miR-4791	CLIP-seq
MIRT1342788	hsa-miR-4793-5p	CLIP-seq
MIRT1342789	hsa-miR-4796-3p	CLIP-seq
MIRT1342790	hsa-miR-4799-3p	CLIP-seq
MIRT1342791	hsa-miR-4802-5p	CLIP-seq
MIRT1342792	hsa-miR-485-5p	CLIP-seq
MIRT1342793	hsa-miR-497	CLIP-seq
MIRT1342794	hsa-miR-5047	CLIP-seq
MIRT1342795	hsa-miR-519a	CLIP-seq
MIRT1342796	hsa-miR-519b-3p	CLIP-seq
MIRT1342797	hsa-miR-519c-3p	CLIP-seq
MIRT1342798	hsa-miR-519d	CLIP-seq
MIRT1342799	hsa-miR-541	CLIP-seq
MIRT1342800	hsa-miR-544b	CLIP-seq
MIRT1342801	hsa-miR-548ah	CLIP-seq
MIRT1342802	hsa-miR-575	CLIP-seq
MIRT1342803	hsa-miR-577	CLIP-seq
MIRT1342804	hsa-miR-584	CLIP-seq
MIRT1342805	hsa-miR-613	CLIP-seq
MIRT1342806	hsa-miR-654-5p	CLIP-seq
MIRT1342807	hsa-miR-670	CLIP-seq
MIRT1342808	hsa-miR-744	CLIP-seq
MIRT1342809	hsa-miR-765	CLIP-seq
MIRT1342810	hsa-miR-875-3p	CLIP-seq
MIRT1342811	hsa-miR-920	CLIP-seq
MIRT1342812	hsa-miR-93	CLIP-seq
MIRT1342813	hsa-miR-935	CLIP-seq
MIRT2101328	hsa-miR-125a-3p	CLIP-seq
MIRT1342703	hsa-miR-1273f	CLIP-seq
MIRT2101329	hsa-miR-129-5p	CLIP-seq
MIRT2101330	hsa-miR-2115	CLIP-seq
MIRT1342720	hsa-miR-23a	CLIP-seq
MIRT1342721	hsa-miR-23b	CLIP-seq
MIRT1342722	hsa-miR-23c	CLIP-seq
MIRT1342723	hsa-miR-24	CLIP-seq
MIRT2101331	hsa-miR-3074-5p	CLIP-seq
MIRT2101332	hsa-miR-3152-3p	CLIP-seq
MIRT2101333	hsa-miR-338-3p	CLIP-seq
MIRT2101334	hsa-miR-3591-5p	CLIP-seq
MIRT2101335	hsa-miR-3606	CLIP-seq
MIRT1342734	hsa-miR-3613-3p	CLIP-seq
MIRT2101336	hsa-miR-3689a-3p	CLIP-seq
MIRT2101337	hsa-miR-3689c	CLIP-seq
MIRT1342739	hsa-miR-371b-5p	CLIP-seq
MIRT2101338	hsa-miR-3913-3p	CLIP-seq
MIRT2101339	hsa-miR-3918	CLIP-seq
MIRT2101340	hsa-miR-3936	CLIP-seq
MIRT2101341	hsa-miR-4267	CLIP-seq
MIRT1342748	hsa-miR-4284	CLIP-seq
MIRT1342752	hsa-miR-4300	CLIP-seq
MIRT2101342	hsa-miR-4431	CLIP-seq
MIRT1342768	hsa-miR-4654	CLIP-seq
MIRT2101343	hsa-miR-4685-5p	CLIP-seq
MIRT2101344	hsa-miR-4722-3p	CLIP-seq
MIRT2101345	hsa-miR-4757-5p	CLIP-seq
MIRT1342785	hsa-miR-4769-5p	CLIP-seq
MIRT2101346	hsa-miR-488	CLIP-seq
MIRT2101347	hsa-miR-489	CLIP-seq
MIRT2101348	hsa-miR-516a-3p	CLIP-seq
MIRT1342799	hsa-miR-541	CLIP-seq
MIRT2101349	hsa-miR-542-3p	CLIP-seq
MIRT1342804	hsa-miR-584	CLIP-seq
MIRT2101350	hsa-miR-615-5p	CLIP-seq
MIRT1342806	hsa-miR-654-5p	CLIP-seq
MIRT1342811	hsa-miR-920	CLIP-seq
MIRT2101351	hsa-miR-921	CLIP-seq
MIRT1342693	hsa-miR-1	CLIP-seq
MIRT1342696	hsa-miR-1184	CLIP-seq
MIRT1342697	hsa-miR-1205	CLIP-seq
MIRT2325718	hsa-miR-1254	CLIP-seq
MIRT1342708	hsa-miR-1299	CLIP-seq
MIRT1342709	hsa-miR-1301	CLIP-seq
MIRT2325719	hsa-miR-1305	CLIP-seq
MIRT2325720	hsa-miR-133a	CLIP-seq
MIRT2325721	hsa-miR-133b	CLIP-seq
MIRT2325722	hsa-miR-1587	CLIP-seq
MIRT2325723	hsa-miR-1912	CLIP-seq
MIRT2325724	hsa-miR-1972	CLIP-seq
MIRT1342716	hsa-miR-206	CLIP-seq
MIRT1342720	hsa-miR-23a	CLIP-seq
MIRT1342721	hsa-miR-23b	CLIP-seq
MIRT1342722	hsa-miR-23c	CLIP-seq
MIRT1342723	hsa-miR-24	CLIP-seq
MIRT2325725	hsa-miR-3116	CLIP-seq
MIRT2325726	hsa-miR-3126-5p	CLIP-seq
MIRT1342728	hsa-miR-3158-5p	CLIP-seq
MIRT2325727	hsa-miR-3199	CLIP-seq
MIRT2325728	hsa-miR-3202	CLIP-seq
MIRT1342734	hsa-miR-3613-3p	CLIP-seq
MIRT2325729	hsa-miR-3665	CLIP-seq
MIRT1342738	hsa-miR-3673	CLIP-seq
MIRT1342739	hsa-miR-371b-5p	CLIP-seq
MIRT2325730	hsa-miR-4253	CLIP-seq
MIRT2325731	hsa-miR-4281	CLIP-seq
MIRT1342748	hsa-miR-4284	CLIP-seq
MIRT2325732	hsa-miR-4287	CLIP-seq
MIRT1342749	hsa-miR-4292	CLIP-seq
MIRT2325733	hsa-miR-4480	CLIP-seq
MIRT2325734	hsa-miR-4492	CLIP-seq
MIRT2325735	hsa-miR-4498	CLIP-seq
MIRT2325736	hsa-miR-4515	CLIP-seq
MIRT1342765	hsa-miR-4639-3p	CLIP-seq
MIRT2325737	hsa-miR-4645-5p	CLIP-seq
MIRT2325738	hsa-miR-4650-5p	CLIP-seq
MIRT1342768	hsa-miR-4654	CLIP-seq
MIRT2325739	hsa-miR-4656	CLIP-seq
MIRT1342769	hsa-miR-4660	CLIP-seq
MIRT2325740	hsa-miR-4671-5p	CLIP-seq
MIRT2325741	hsa-miR-4673	CLIP-seq
MIRT2325742	hsa-miR-4675	CLIP-seq
MIRT2325743	hsa-miR-4685-3p	CLIP-seq
MIRT2325744	hsa-miR-4690-3p	CLIP-seq
MIRT2101344	hsa-miR-4722-3p	CLIP-seq
MIRT2325745	hsa-miR-4731-5p	CLIP-seq
MIRT2325746	hsa-miR-4741	CLIP-seq
MIRT2101345	hsa-miR-4757-5p	CLIP-seq
MIRT1342785	hsa-miR-4769-5p	CLIP-seq
MIRT1342786	hsa-miR-4789-3p	CLIP-seq
MIRT2325747	hsa-miR-486-3p	CLIP-seq
MIRT1342794	hsa-miR-5047	CLIP-seq
MIRT1342795	hsa-miR-519a	CLIP-seq
MIRT1342796	hsa-miR-519b-3p	CLIP-seq
MIRT1342797	hsa-miR-519c-3p	CLIP-seq
MIRT1342799	hsa-miR-541	CLIP-seq
MIRT2325748	hsa-miR-544	CLIP-seq
MIRT1342800	hsa-miR-544b	CLIP-seq
MIRT2325749	hsa-miR-551a	CLIP-seq
MIRT2325750	hsa-miR-551b	CLIP-seq
MIRT1342804	hsa-miR-584	CLIP-seq
MIRT2325751	hsa-miR-607	CLIP-seq
MIRT1342805	hsa-miR-613	CLIP-seq
MIRT1342806	hsa-miR-654-5p	CLIP-seq
MIRT2325752	hsa-miR-657	CLIP-seq
MIRT2325753	hsa-miR-762	CLIP-seq
MIRT1342810	hsa-miR-875-3p	CLIP-seq
MIRT2101350	hsa-miR-615-5p	CLIP-seq
MIRT1342699	hsa-miR-1237	CLIP-seq
MIRT1342700	hsa-miR-1245b-5p	CLIP-seq
MIRT1342703	hsa-miR-1273f	CLIP-seq
MIRT1342711	hsa-miR-15a	CLIP-seq
MIRT1342712	hsa-miR-15b	CLIP-seq
MIRT1342713	hsa-miR-16	CLIP-seq
MIRT1342715	hsa-miR-195	CLIP-seq
MIRT1342727	hsa-miR-3142	CLIP-seq
MIRT1342741	hsa-miR-3922-5p	CLIP-seq
MIRT1342744	hsa-miR-424	CLIP-seq
MIRT1342752	hsa-miR-4300	CLIP-seq
MIRT1342763	hsa-miR-4530	CLIP-seq
MIRT1342767	hsa-miR-4649-3p	CLIP-seq
MIRT1342770	hsa-miR-4663	CLIP-seq
MIRT1342774	hsa-miR-4708-3p	CLIP-seq
MIRT1342793	hsa-miR-497	CLIP-seq
MIRT1342811	hsa-miR-920	CLIP-seq
MIRT1342699	hsa-miR-1237	CLIP-seq
MIRT1342700	hsa-miR-1245b-5p	CLIP-seq
MIRT1342727	hsa-miR-3142	CLIP-seq
MIRT1342741	hsa-miR-3922-5p	CLIP-seq
MIRT1342767	hsa-miR-4649-3p	CLIP-seq
MIRT1342770	hsa-miR-4663	CLIP-seq
MIRT1342774	hsa-miR-4708-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IDA	30442778
GO:0005739	Component	Mitochondrion	IEA
GO:0005743	Component	Mitochondrial inner membrane	IBA
GO:0005743	Component	Mitochondrial inner membrane	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006865	Process	Amino acid transport	IEA
GO:0015075	Function	Monoatomic ion transmembrane transporter activity	IEA
GO:0015137	Function	Citrate transmembrane transporter activity	IBA
GO:0015746	Process	Citrate transport	IBA
GO:0016020	Component	Membrane	IEA
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0055085	Process	Transmembrane transport	IEA
GO:0120162	Process	Positive regulation of cold-induced thermogenesis	IEA
GO:1990542	Process	Mitochondrial transmembrane transport	IBA

Other IDs

• MIM: 615572
• HGNC: 16073
• e!Ensembl: ENSG00000144040

Protein

• UniProt ID: Q8TD22
• Protein name: Sideroflexin-5
• Protein function: Mitochondrial amino-acid transporter (By similarity). Transports citrate (By similarity). Does not act as a serine transporter: not able to mediate transport of serine into mitochondria (By similarity) (PubMed:30442778). In brown adipose tissue,
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03820	SFXNs	26 → 340	Sideroflexins	Family

• Tissue specificity: TISSUE SPECIFICITY: Primarily expressed in the brain. {ECO:0000269|PubMed:12039050}.
• Sequence:

  MADTATTASAAAASAASASSDAPPFQLGKPRFQQTSFYGRFRHFLDIIDPRTLFVTERRL
  REAVQLLEDYKHGTLRPGVTNEQLWSAQKIKQAILHPDTNEKIFMPFRMSGYIPFGTPIV
  VGLLLPNQTLASTVFWQWLNQSHNACVNYANRNATKPSPASKFIQGYLGAVISAVSIAVG
  LNVLVQKANKFTPATRLLIQRFVPFPAVASANICNVVLMRYGELEEGIDVLDSDGNLVGS
  SKIAARHALLETALTRVVLPMPILVLPPIVMSMLEKTALLQARPRLLLPVQSLVCLAAFG
  LALPLAISLFPQMSEIETSQLEPEIAQATSSRTVVYNKGL

• Sequence length: 340

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Ovarian serous cystadenocarcinoma	Likely benign	rs372681038	RCV005930710