SFXN1 (sideroflexin 1)
| Gene | |
|
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
94081 |
|
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Sideroflexin 1 |
|
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
SFXN1 |
|
Synonyms (NCBI Gene)
Gene synonyms aliases
|
SLC56A1, TCC |
|
Chromosome
Chromosome number
|
5 |
|
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
5q35.2 |
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
|||||||
| Protein | |||||||||||
| UniProt ID | Q9H9B4 | ||||||||||
| Protein name | Sideroflexin-1 | ||||||||||
| Protein function | Amino acid transporter importing serine, an essential substrate of the mitochondrial branch of the one-carbon pathway, into mitochondria. Mitochondrial serine is then converted to glycine and formate, which exits to the cytosol where it is used | ||||||||||
| Family and domains |
Pfam
|
||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in tissues with high one-carbon metabolism activity, such as blood, liver and kidney. {ECO:0000269|PubMed:30442778}. | ||||||||||
| Sequence |
|
||||||||||
| Sequence length | 322 | ||||||||||
| Interactions | View interactions | ||||||||||
|
Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
|
||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||