ZNF101 (zinc finger protein 101)

Gene

• Entrez ID: 94039
• Gene name: Zinc finger protein 101
• Gene symbol: ZNF101
• Synonyms (NCBI Gene): HZF12
• Chromosome: 19
• Chromosome location: 19p13.11
• Summary: Zinc finger proteins (ZNFs), such as ZNF101, bind nucleic acids and perform many key functions, the most important of which is regulating transcription (summary by Bellefroid et al., 1993 [PubMed 8467795]). See ZNF91 (MIM 603971) for general information o

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT052716	hsa-miR-1260b	CLASH	23622248
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT689370	hsa-miR-483-5p	HITS-CLIP	23313552
MIRT669763	hsa-miR-4781-3p	HITS-CLIP	23313552
MIRT669762	hsa-miR-4716-5p	HITS-CLIP	23313552
MIRT669760	hsa-miR-4635	HITS-CLIP	23313552
MIRT669759	hsa-miR-4680-5p	HITS-CLIP	23313552
MIRT669755	hsa-miR-8086	HITS-CLIP	23313552
MIRT669754	hsa-miR-193b-5p	HITS-CLIP	23313552
MIRT669753	hsa-miR-197-3p	HITS-CLIP	23313552
MIRT669751	hsa-miR-7158-3p	HITS-CLIP	23313552
MIRT669750	hsa-miR-203b-3p	HITS-CLIP	23313552
MIRT451275	hsa-miR-548s	HITS-CLIP	23313552
MIRT669749	hsa-miR-4701-5p	HITS-CLIP	23313552
MIRT669748	hsa-miR-588	HITS-CLIP	23313552
MIRT669747	hsa-miR-4435	HITS-CLIP	23313552
MIRT669746	hsa-miR-3187-3p	HITS-CLIP	23313552
MIRT669745	hsa-miR-5096	HITS-CLIP	23313552
MIRT689369	hsa-miR-1303	HITS-CLIP	23313552
MIRT669744	hsa-miR-3157-5p	HITS-CLIP	23313552
MIRT689368	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT689367	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT451281	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT689366	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT689365	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT689364	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT689363	hsa-miR-4486	HITS-CLIP	23313552
MIRT689362	hsa-miR-5186	HITS-CLIP	23313552
MIRT689361	hsa-miR-4537	HITS-CLIP	23313552
MIRT689360	hsa-miR-4252	HITS-CLIP	23313552
MIRT689359	hsa-miR-661	HITS-CLIP	23313552
MIRT689358	hsa-miR-1273a	HITS-CLIP	23313552
MIRT689357	hsa-miR-4649-5p	HITS-CLIP	23313552
MIRT689356	hsa-miR-6729-5p	HITS-CLIP	23313552
MIRT689355	hsa-miR-1227-3p	HITS-CLIP	23313552
MIRT689354	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT689353	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT689352	hsa-miR-7703	HITS-CLIP	23313552
MIRT689351	hsa-miR-550b-2-5p	HITS-CLIP	23313552
MIRT689350	hsa-miR-5004-5p	HITS-CLIP	23313552
MIRT669763	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT669762	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT669761	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669760	hsa-miR-4635	HITS-CLIP	23824327
MIRT669759	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT669758	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669757	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669756	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT669755	hsa-miR-8086	HITS-CLIP	23824327
MIRT669754	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT669753	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT669752	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669751	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT669750	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT451275	hsa-miR-548s	HITS-CLIP	23824327
MIRT669749	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT669748	hsa-miR-588	HITS-CLIP	23824327
MIRT669747	hsa-miR-4435	HITS-CLIP	23824327
MIRT669746	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT669745	hsa-miR-5096	HITS-CLIP	23824327
MIRT669744	hsa-miR-3157-5p	HITS-CLIP	23824327
MIRT661163	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT661162	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT661161	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT661160	hsa-miR-4308	HITS-CLIP	23824327
MIRT661159	hsa-miR-4292	HITS-CLIP	23824327
MIRT661158	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT661157	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT661156	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT661155	hsa-miR-5695	HITS-CLIP	23824327
MIRT661154	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT661153	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT661152	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT661151	hsa-miR-4634	HITS-CLIP	23824327
MIRT661150	hsa-miR-4284	HITS-CLIP	23824327
MIRT661149	hsa-miR-498	HITS-CLIP	23824327
MIRT451299	hsa-miR-302f	PAR-CLIP	23446348
MIRT451298	hsa-miR-1295b-5p	PAR-CLIP	23446348
MIRT451297	hsa-miR-1912	PAR-CLIP	23446348
MIRT451296	hsa-miR-6165	PAR-CLIP	23446348
MIRT451295	hsa-miR-6847-5p	PAR-CLIP	23446348
MIRT451294	hsa-miR-4257	PAR-CLIP	23446348
MIRT451293	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT451292	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT451291	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT451290	hsa-miR-1273e	PAR-CLIP	23446348
MIRT451299	hsa-miR-302f	PAR-CLIP	23592263
MIRT451298	hsa-miR-1295b-5p	PAR-CLIP	23592263
MIRT451297	hsa-miR-1912	PAR-CLIP	23592263
MIRT451296	hsa-miR-6165	PAR-CLIP	23592263
MIRT451295	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT451294	hsa-miR-4257	PAR-CLIP	23592263
MIRT451293	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT451292	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT451291	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT451290	hsa-miR-1273e	PAR-CLIP	23592263
MIRT451289	hsa-miR-548ac	PAR-CLIP	23592263
MIRT451288	hsa-miR-548bb-3p	PAR-CLIP	23592263
MIRT451287	hsa-miR-548d-3p	PAR-CLIP	23592263
MIRT451286	hsa-miR-548h-3p	PAR-CLIP	23592263
MIRT451285	hsa-miR-548z	PAR-CLIP	23592263
MIRT451284	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT451283	hsa-miR-4491	PAR-CLIP	23592263
MIRT451282	hsa-miR-4657	PAR-CLIP	23592263
MIRT451281	hsa-miR-6849-3p	PAR-CLIP	23592263
MIRT451280	hsa-miR-3190-5p	PAR-CLIP	23592263
MIRT451279	hsa-miR-3148	PAR-CLIP	23592263
MIRT451278	hsa-miR-6124	PAR-CLIP	23592263
MIRT451277	hsa-miR-3926	PAR-CLIP	23592263
MIRT451276	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT451275	hsa-miR-548s	PAR-CLIP	23592263
MIRT451274	hsa-miR-6833-5p	PAR-CLIP	23592263
MIRT451273	hsa-miR-576-3p	PAR-CLIP	23592263
MIRT451299	hsa-miR-302f	PAR-CLIP	27292025
MIRT451293	hsa-miR-4768-3p	PAR-CLIP	27292025
MIRT689369	hsa-miR-1303	HITS-CLIP	27418678
MIRT669754	hsa-miR-193b-5p	HITS-CLIP	27418678
MIRT669753	hsa-miR-197-3p	HITS-CLIP	27418678
MIRT669744	hsa-miR-3157-5p	HITS-CLIP	27418678
MIRT669746	hsa-miR-3187-3p	HITS-CLIP	27418678
MIRT669747	hsa-miR-4435	HITS-CLIP	27418678
MIRT669749	hsa-miR-4701-5p	HITS-CLIP	27418678
MIRT669762	hsa-miR-4716-5p	HITS-CLIP	27418678
MIRT669756	hsa-miR-4755-3p	HITS-CLIP	27418678
MIRT669763	hsa-miR-4781-3p	HITS-CLIP	27418678
MIRT689370	hsa-miR-483-5p	HITS-CLIP	27418678
MIRT669745	hsa-miR-5096	HITS-CLIP	27418678
MIRT451275	hsa-miR-548s	HITS-CLIP	27418678
MIRT669748	hsa-miR-588	HITS-CLIP	27418678
MIRT669755	hsa-miR-8086	HITS-CLIP	27418678
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT708280	hsa-miR-6856-3p	HITS-CLIP	19536157
MIRT708279	hsa-miR-4690-3p	HITS-CLIP	19536157
MIRT708278	hsa-miR-5685	HITS-CLIP	19536157
MIRT689360	hsa-miR-4252	HITS-CLIP	19536157
MIRT708277	hsa-miR-4641	HITS-CLIP	19536157
MIRT708276	hsa-miR-6731-5p	HITS-CLIP	19536157
MIRT708275	hsa-miR-8085	HITS-CLIP	19536157
MIRT708274	hsa-miR-3175	HITS-CLIP	19536157
MIRT689370	hsa-miR-483-5p	HITS-CLIP	23313552
MIRT669763	hsa-miR-4781-3p	HITS-CLIP	23313552
MIRT669762	hsa-miR-4716-5p	HITS-CLIP	23313552
MIRT669760	hsa-miR-4635	HITS-CLIP	23313552
MIRT669759	hsa-miR-4680-5p	HITS-CLIP	23313552
MIRT669755	hsa-miR-8086	HITS-CLIP	23313552
MIRT669754	hsa-miR-193b-5p	HITS-CLIP	23313552
MIRT669753	hsa-miR-197-3p	HITS-CLIP	23313552
MIRT669751	hsa-miR-7158-3p	HITS-CLIP	23313552
MIRT669750	hsa-miR-203b-3p	HITS-CLIP	23313552
MIRT451275	hsa-miR-548s	HITS-CLIP	23313552
MIRT669749	hsa-miR-4701-5p	HITS-CLIP	23313552
MIRT669748	hsa-miR-588	HITS-CLIP	23313552
MIRT669747	hsa-miR-4435	HITS-CLIP	23313552
MIRT669746	hsa-miR-3187-3p	HITS-CLIP	23313552
MIRT669745	hsa-miR-5096	HITS-CLIP	23313552
MIRT689369	hsa-miR-1303	HITS-CLIP	23313552
MIRT669744	hsa-miR-3157-5p	HITS-CLIP	23313552
MIRT689368	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT689367	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT451281	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT689366	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT689365	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT689364	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT689363	hsa-miR-4486	HITS-CLIP	23313552
MIRT689362	hsa-miR-5186	HITS-CLIP	23313552
MIRT689361	hsa-miR-4537	HITS-CLIP	23313552
MIRT689360	hsa-miR-4252	HITS-CLIP	23313552
MIRT689359	hsa-miR-661	HITS-CLIP	23313552
MIRT689358	hsa-miR-1273a	HITS-CLIP	23313552
MIRT689357	hsa-miR-4649-5p	HITS-CLIP	23313552
MIRT689356	hsa-miR-6729-5p	HITS-CLIP	23313552
MIRT689355	hsa-miR-1227-3p	HITS-CLIP	23313552
MIRT689354	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT689353	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT689352	hsa-miR-7703	HITS-CLIP	23313552
MIRT689351	hsa-miR-550b-2-5p	HITS-CLIP	23313552
MIRT689350	hsa-miR-5004-5p	HITS-CLIP	23313552
MIRT669763	hsa-miR-4781-3p	HITS-CLIP	23824327
MIRT669762	hsa-miR-4716-5p	HITS-CLIP	23824327
MIRT669761	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669760	hsa-miR-4635	HITS-CLIP	23824327
MIRT669759	hsa-miR-4680-5p	HITS-CLIP	23824327
MIRT669758	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669757	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669756	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT669755	hsa-miR-8086	HITS-CLIP	23824327
MIRT669754	hsa-miR-193b-5p	HITS-CLIP	23824327
MIRT669753	hsa-miR-197-3p	HITS-CLIP	23824327
MIRT669752	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669751	hsa-miR-7158-3p	HITS-CLIP	23824327
MIRT669750	hsa-miR-203b-3p	HITS-CLIP	23824327
MIRT451275	hsa-miR-548s	HITS-CLIP	23824327
MIRT669749	hsa-miR-4701-5p	HITS-CLIP	23824327
MIRT669748	hsa-miR-588	HITS-CLIP	23824327
MIRT669747	hsa-miR-4435	HITS-CLIP	23824327
MIRT669746	hsa-miR-3187-3p	HITS-CLIP	23824327
MIRT669745	hsa-miR-5096	HITS-CLIP	23824327
MIRT669744	hsa-miR-3157-5p	HITS-CLIP	23824327
MIRT661163	hsa-miR-2114-5p	HITS-CLIP	23824327
MIRT661162	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT661161	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT661160	hsa-miR-4308	HITS-CLIP	23824327
MIRT661159	hsa-miR-4292	HITS-CLIP	23824327
MIRT661158	hsa-miR-6791-5p	HITS-CLIP	23824327
MIRT661157	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT661156	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT661155	hsa-miR-5695	HITS-CLIP	23824327
MIRT661154	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT661153	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT661152	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT661151	hsa-miR-4634	HITS-CLIP	23824327
MIRT661150	hsa-miR-4284	HITS-CLIP	23824327
MIRT661149	hsa-miR-498	HITS-CLIP	23824327
MIRT451299	hsa-miR-302f	PAR-CLIP	23446348
MIRT451298	hsa-miR-1295b-5p	PAR-CLIP	23446348
MIRT451297	hsa-miR-1912	PAR-CLIP	23446348
MIRT451296	hsa-miR-6165	PAR-CLIP	23446348
MIRT451295	hsa-miR-6847-5p	PAR-CLIP	23446348
MIRT451294	hsa-miR-4257	PAR-CLIP	23446348
MIRT451293	hsa-miR-4768-3p	PAR-CLIP	23446348
MIRT451292	hsa-miR-219b-3p	PAR-CLIP	23446348
MIRT451291	hsa-miR-4722-5p	PAR-CLIP	23446348
MIRT451290	hsa-miR-1273e	PAR-CLIP	23446348
MIRT451299	hsa-miR-302f	PAR-CLIP	23592263
MIRT451298	hsa-miR-1295b-5p	PAR-CLIP	23592263
MIRT451297	hsa-miR-1912	PAR-CLIP	23592263
MIRT451296	hsa-miR-6165	PAR-CLIP	23592263
MIRT451295	hsa-miR-6847-5p	PAR-CLIP	23592263
MIRT451294	hsa-miR-4257	PAR-CLIP	23592263
MIRT451293	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT451292	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT451291	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT451290	hsa-miR-1273e	PAR-CLIP	23592263
MIRT451289	hsa-miR-548ac	PAR-CLIP	23592263
MIRT451288	hsa-miR-548bb-3p	PAR-CLIP	23592263
MIRT451287	hsa-miR-548d-3p	PAR-CLIP	23592263
MIRT451286	hsa-miR-548h-3p	PAR-CLIP	23592263
MIRT451285	hsa-miR-548z	PAR-CLIP	23592263
MIRT451284	hsa-miR-548as-3p	PAR-CLIP	23592263
MIRT451283	hsa-miR-4491	PAR-CLIP	23592263
MIRT451282	hsa-miR-4657	PAR-CLIP	23592263
MIRT451281	hsa-miR-6849-3p	PAR-CLIP	23592263
MIRT451280	hsa-miR-3190-5p	PAR-CLIP	23592263
MIRT451279	hsa-miR-3148	PAR-CLIP	23592263
MIRT451278	hsa-miR-6124	PAR-CLIP	23592263
MIRT451277	hsa-miR-3926	PAR-CLIP	23592263
MIRT451276	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT451275	hsa-miR-548s	PAR-CLIP	23592263
MIRT451274	hsa-miR-6833-5p	PAR-CLIP	23592263
MIRT451273	hsa-miR-576-3p	PAR-CLIP	23592263

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 603983
• HGNC: 12881
• e!Ensembl: ENSG00000181896

Protein

• UniProt ID: Q8IZC7
• Protein name: Zinc finger protein 101 (Zinc finger protein HZF12)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01352	KRAB	3 → 44	KRAB box	Family
  PF00096	zf-C2H2	169 → 191	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	225 → 247	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	253 → 276	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	338 → 360	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	394 → 416	Zinc finger, C2H2 type	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed in a variety of adult and fetal tissues. {ECO:0000269|PubMed:14727140}.
• Sequence:

  MDSVAFEDVAVNFTQEEWALLSPSQKNLYRDVTLETFRNLASVGIQWKDQDIENLYQNLG
  IKLRSLVERLCGRKEGNEHRETFSQIPDCHLNKKSQTGVKPCKCSVCGKVFLRHSFLDRH
  MRAHAGHKRSECGGEWRETPRKQKQHGKASISPSSGARRTVTPTRKRPYECKVCGKAFNS
  PNLFQIHQRTHTGKRSYKCREIVRAFTVSSFFRKHGKMHTGEKRYECKYCGKPIDYPSLF
  QIHVRTHTGEKPYKCKQCGKAFISAGYLRTHEIRSHALEKSHQCQECGKKLSCSSSLHRH
  ERTHSGGKLYECQKCAKVFRCPTSLQAHERAHTGERPYECNKCGKTFNYPSCFRRHKKTH
  SGEKPYECTRCGKAFGWCSSLRRHEMTHTGEKPFDCKQCGKVFTFSNYLRLHERTHLAGR
  SQCFGRRQGDHLSPGV

• Sequence length: 436

Pathways

Reactome:

Generic Transcription Pathway

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs80356663, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs371977235, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	22885922

Unknown
Disease term	Disease name	Evidence	References	Source
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA
Diabetes	Diabetes			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Multiple Sclerosis	Associate	34956196