STOML1 (stomatin like 1)

Gene

• Entrez ID: 9399
• Gene name: Stomatin like 1
• Gene symbol: STOML1
• Synonyms (NCBI Gene): SLP-1, STORP, hUNC-24
• Chromosome: 15
• Chromosome location: 15q24.1

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT669823	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669822	hsa-miR-764	HITS-CLIP	23824327
MIRT669821	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT669820	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT669819	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT669818	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT669817	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT669816	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT669815	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT669814	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT669813	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT669811	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669812	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT669810	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669809	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669808	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT669807	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669806	hsa-miR-640	HITS-CLIP	23824327
MIRT669805	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT669804	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641874	hsa-miR-8485	HITS-CLIP	23824327
MIRT641873	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT641872	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641870	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT641869	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT641868	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT641867	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT641866	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT641865	hsa-miR-4469	HITS-CLIP	23824327
MIRT641864	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT641863	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT641862	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT641861	hsa-miR-6837-3p	HITS-CLIP	23824327
MIRT641860	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT641859	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT641858	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT514497	hsa-miR-5692a	PAR-CLIP	23446348
MIRT514495	hsa-miR-6858-3p	PAR-CLIP	23446348
MIRT514494	hsa-miR-3197	PAR-CLIP	23446348
MIRT514493	hsa-miR-3194-5p	PAR-CLIP	23446348
MIRT514492	hsa-miR-877-5p	PAR-CLIP	23446348
MIRT514491	hsa-miR-6866-5p	PAR-CLIP	23446348
MIRT669823	hsa-miR-125a-3p	HITS-CLIP	23824327
MIRT669822	hsa-miR-764	HITS-CLIP	23824327
MIRT669821	hsa-miR-3934-5p	HITS-CLIP	23824327
MIRT669820	hsa-miR-6747-3p	HITS-CLIP	23824327
MIRT669819	hsa-miR-1234-3p	HITS-CLIP	23824327
MIRT669818	hsa-miR-7107-5p	HITS-CLIP	23824327
MIRT669817	hsa-miR-371b-5p	HITS-CLIP	23824327
MIRT669816	hsa-miR-373-5p	HITS-CLIP	23824327
MIRT669815	hsa-miR-616-5p	HITS-CLIP	23824327
MIRT669814	hsa-miR-371a-5p	HITS-CLIP	23824327
MIRT669813	hsa-miR-372-5p	HITS-CLIP	23824327
MIRT669811	hsa-miR-3653-5p	HITS-CLIP	23824327
MIRT669812	hsa-miR-3663-5p	HITS-CLIP	23824327
MIRT669810	hsa-miR-6790-3p	HITS-CLIP	23824327
MIRT669809	hsa-miR-6821-3p	HITS-CLIP	23824327
MIRT669808	hsa-miR-6778-3p	HITS-CLIP	23824327
MIRT669807	hsa-miR-378a-5p	HITS-CLIP	23824327
MIRT669806	hsa-miR-640	HITS-CLIP	23824327
MIRT669805	hsa-miR-6843-3p	HITS-CLIP	23824327
MIRT669804	hsa-miR-6848-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641874	hsa-miR-8485	HITS-CLIP	23824327
MIRT641873	hsa-miR-329-3p	HITS-CLIP	23824327
MIRT641872	hsa-miR-362-3p	HITS-CLIP	23824327
MIRT641871	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT641870	hsa-miR-6865-3p	HITS-CLIP	23824327
MIRT641869	hsa-miR-4667-3p	HITS-CLIP	23824327
MIRT641868	hsa-miR-6892-3p	HITS-CLIP	23824327
MIRT641867	hsa-miR-2276-5p	HITS-CLIP	23824327
MIRT641866	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT641865	hsa-miR-4469	HITS-CLIP	23824327
MIRT641864	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT641863	hsa-miR-412-3p	HITS-CLIP	23824327
MIRT641862	hsa-miR-6754-3p	HITS-CLIP	23824327
MIRT641861	hsa-miR-6837-3p	HITS-CLIP	23824327
MIRT641860	hsa-miR-377-3p	HITS-CLIP	23824327
MIRT641859	hsa-miR-642a-5p	HITS-CLIP	23824327
MIRT641858	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT514497	hsa-miR-5692a	PAR-CLIP	23446348
MIRT514495	hsa-miR-6858-3p	PAR-CLIP	23446348
MIRT514494	hsa-miR-3197	PAR-CLIP	23446348
MIRT514493	hsa-miR-3194-5p	PAR-CLIP	23446348
MIRT514492	hsa-miR-877-5p	PAR-CLIP	23446348
MIRT514491	hsa-miR-6866-5p	PAR-CLIP	23446348
MIRT1399003	hsa-miR-1258	CLIP-seq
MIRT1399004	hsa-miR-1296	CLIP-seq
MIRT1399005	hsa-miR-2909	CLIP-seq
MIRT1399006	hsa-miR-4512	CLIP-seq
MIRT2119621	hsa-miR-2355-5p	CLIP-seq
MIRT2119622	hsa-miR-2861	CLIP-seq
MIRT2119623	hsa-miR-3652	CLIP-seq
MIRT2119624	hsa-miR-4430	CLIP-seq
MIRT2119625	hsa-miR-4487	CLIP-seq
MIRT2119626	hsa-miR-4505	CLIP-seq
MIRT2119627	hsa-miR-4661-3p	CLIP-seq
MIRT2119628	hsa-miR-4726-3p	CLIP-seq
MIRT2119629	hsa-miR-647	CLIP-seq
MIRT2341763	hsa-miR-1183	CLIP-seq
MIRT2341764	hsa-miR-1291	CLIP-seq
MIRT2341765	hsa-miR-198	CLIP-seq
MIRT2341766	hsa-miR-214	CLIP-seq
MIRT2341767	hsa-miR-3173-5p	CLIP-seq
MIRT2341768	hsa-miR-3619-5p	CLIP-seq
MIRT2341769	hsa-miR-3667-3p	CLIP-seq
MIRT2341770	hsa-miR-3919	CLIP-seq
MIRT2341771	hsa-miR-3925-5p	CLIP-seq
MIRT2341772	hsa-miR-4268	CLIP-seq
MIRT2341773	hsa-miR-4448	CLIP-seq
MIRT2341774	hsa-miR-520a-5p	CLIP-seq
MIRT2341775	hsa-miR-525-5p	CLIP-seq
MIRT2341776	hsa-miR-589	CLIP-seq
MIRT2341777	hsa-miR-761	CLIP-seq
MIRT2635678	hsa-miR-1207-3p	CLIP-seq
MIRT2635679	hsa-miR-1228	CLIP-seq
MIRT2635680	hsa-miR-1285	CLIP-seq
MIRT2635681	hsa-miR-1973	CLIP-seq
MIRT2341765	hsa-miR-198	CLIP-seq
MIRT2635682	hsa-miR-3144-5p	CLIP-seq
MIRT2635683	hsa-miR-3187-5p	CLIP-seq
MIRT2635684	hsa-miR-3191	CLIP-seq
MIRT2341770	hsa-miR-3919	CLIP-seq
MIRT2341771	hsa-miR-3925-5p	CLIP-seq
MIRT2635685	hsa-miR-4267	CLIP-seq
MIRT2635686	hsa-miR-4312	CLIP-seq
MIRT2635687	hsa-miR-4652-5p	CLIP-seq
MIRT2635688	hsa-miR-4667-5p	CLIP-seq
MIRT2635689	hsa-miR-4700-5p	CLIP-seq
MIRT2635690	hsa-miR-4731-5p	CLIP-seq
MIRT2635691	hsa-miR-512-5p	CLIP-seq
MIRT2341774	hsa-miR-520a-5p	CLIP-seq
MIRT2341775	hsa-miR-525-5p	CLIP-seq
MIRT2341776	hsa-miR-589	CLIP-seq
MIRT2635692	hsa-miR-612	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19696025, 23082202
GO:0005768	Component	Endosome	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0006869	Process	Lipid transport	IEA
GO:0008200	Function	Ion channel inhibitor activity	IBA
GO:0016020	Component	Membrane	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0031902	Component	Late endosome membrane	IEA
GO:0045121	Component	Membrane raft	IEA

Other IDs

• MIM: 608326
• HGNC: 14560
• e!Ensembl: ENSG00000067221

Protein

• UniProt ID: Q9UBI4
• Protein name: Stomatin-like protein 1 (SLP-1) (EPB72-like protein 1) (Protein unc-24 homolog) (Stomatin-related protein) (STORP)
• Protein function: May play a role in cholesterol transfer to late endosomes (PubMed:19696025). May play a role in modulating membrane acid-sensing ion channels. Can specifically inhibit proton-gated current of ASIC1 isoform 1. Can increase inactivation speed of A
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01145	Band_7	80 → 228	SPFH domain / Band 7 family	Family
  PF02036	SCP2	291 → 395	SCP-2 sterol transfer family	Family

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed at low levels. Expression is highest in brain. {ECO:0000269|PubMed:10997330, ECO:0000269|PubMed:9931417}.
• Sequence:

  MLGRSGYRALPLGDFDRFQQSSFGFLGSQKGCLSPERGGVGTGADVPQSWPSCLCHGLIS
  FLGFLLLLVTFPISGWFALKIVPTYERMIVFRLGRIRTPQGPGMVLLLPFIDSFQRVDLR
  TRAFNVPPCKLASKDGAVLSVGADVQFRIWDPVLSVMTVKDLNTATRMTAQNAMTKALLK
  RPLREIQMEKLKISDQLLLEINDVTRAWGLEVDRVELAVEAVLQPPQDSPAGPNLDSTLQ
  QLALHFLGGSMNSMAGGAPSPGPADTVEMVSEVEPPAPQVGARSSPKQPLAEGLLTALQP
  FLSEALVSQVGACYQFNVVLPSGTQSAYFLDLTTGRGRVGHGVPDGIPDVVVEMAEADLR
  ALLCRELRPLGAYMSGRLKVKGDLAMAMKLEAVLRALK

• Sequence length: 398