Gene Gene information from NCBI Gene database.
Entrez ID 9397
Gene name N-myristoyltransferase 2
Gene symbol NMT2
Synonyms (NCBI Gene)
-
Chromosome 10
Chromosome location 10p13
Summary This gene encodes one of two N-myristoyltransferase proteins. N-terminal myristoylation is a lipid modification that is involved in regulating the function and localization of signaling proteins. The encoded protein catalyzes the addition of a myristoyl g
miRNA miRNA information provided by mirtarbase database.
537
miRTarBase ID miRNA Experiments Reference
MIRT727078 hsa-miR-181a-5p HITS-CLIP 22473208
MIRT727077 hsa-miR-181b-5p HITS-CLIP 22473208
MIRT727076 hsa-miR-181c-5p HITS-CLIP 22473208
MIRT727075 hsa-miR-181d-5p HITS-CLIP 22473208
MIRT1187898 hsa-miR-106a CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
23
GO ID Ontology Definition Evidence Reference
GO:0004379 Function Glycylpeptide N-tetradecanoyltransferase activity IBA
GO:0004379 Function Glycylpeptide N-tetradecanoyltransferase activity IDA 25255805, 32103017
GO:0004379 Function Glycylpeptide N-tetradecanoyltransferase activity IEA
GO:0004379 Function Glycylpeptide N-tetradecanoyltransferase activity TAS
GO:0005515 Function Protein binding IPI 16530191, 21900206, 23150525, 26621918, 28514442, 32296183, 32814053, 33961781, 35271311
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603801 7858 ENSG00000152465
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O60551
Protein name Glycylpeptide N-tetradecanoyltransferase 2 (EC 2.3.1.97) (Myristoyl-CoA:protein N-myristoyltransferase 2) (NMT 2) (Peptide N-myristoyltransferase 2) (Protein-lysine myristoyltransferase NMT2) (EC 2.3.1.-) (Type II N-myristoyltransferase)
Protein function Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins (PubMed:25255805, PubMed:9506952). Also able to mediate N-terminal lysine myristoylation of proteins: catalyzes myristoylation of ARF6 on both 'Gly-2
PDB 4C2X , 6PAU
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01233 NMT 139 296 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Domain
PF02799 NMT_C 310 496 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Domain
Sequence
Sequence length 498
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Membrane binding and targetting of GAG proteins
Inactivation, recovery and regulation of the phototransduction cascade