Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	93517
Gene name	Short chain dehydrogenase/reductase family 42E, member 1
Gene symbol	SDR42E1
Synonyms (NCBI Gene)	HSPC105
Chromosome	16
Chromosome location	16q23.3

112

Show/Hide all (112)

miRTarBase ID	miRNA	Experiments	Reference
MIRT499662	hsa-miR-548an	PAR-CLIP	24398324
MIRT499661	hsa-miR-6768-3p	PAR-CLIP	24398324
MIRT499660	hsa-miR-4484	PAR-CLIP	24398324
MIRT499659	hsa-miR-3927-3p	PAR-CLIP	24398324
MIRT499657	hsa-miR-6831-5p	PAR-CLIP	24398324
MIRT499658	hsa-let-7a-5p	PAR-CLIP	24398324
MIRT499656	hsa-let-7b-5p	PAR-CLIP	24398324
MIRT499655	hsa-let-7c-5p	PAR-CLIP	24398324
MIRT499654	hsa-let-7d-5p	PAR-CLIP	24398324
MIRT499653	hsa-let-7e-5p	PAR-CLIP	24398324
MIRT499652	hsa-let-7f-5p	PAR-CLIP	24398324
MIRT499651	hsa-let-7g-5p	PAR-CLIP	24398324
MIRT499650	hsa-let-7i-5p	PAR-CLIP	24398324
MIRT499649	hsa-miR-4458	PAR-CLIP	24398324
MIRT499648	hsa-miR-4500	PAR-CLIP	24398324
MIRT499647	hsa-miR-98-5p	PAR-CLIP	24398324
MIRT499646	hsa-miR-202-3p	PAR-CLIP	24398324
MIRT499645	hsa-miR-4650-3p	PAR-CLIP	24398324
MIRT499644	hsa-miR-202-5p	PAR-CLIP	24398324
MIRT499662	hsa-miR-548an	PAR-CLIP	24398324
MIRT499661	hsa-miR-6768-3p	PAR-CLIP	24398324
MIRT499660	hsa-miR-4484	PAR-CLIP	24398324
MIRT499659	hsa-miR-3927-3p	PAR-CLIP	24398324
MIRT499657	hsa-miR-6831-5p	PAR-CLIP	24398324
MIRT499658	hsa-let-7a-5p	PAR-CLIP	24398324
MIRT499656	hsa-let-7b-5p	PAR-CLIP	24398324
MIRT499655	hsa-let-7c-5p	PAR-CLIP	24398324
MIRT499654	hsa-let-7d-5p	PAR-CLIP	24398324
MIRT499653	hsa-let-7e-5p	PAR-CLIP	24398324
MIRT499652	hsa-let-7f-5p	PAR-CLIP	24398324
MIRT499651	hsa-let-7g-5p	PAR-CLIP	24398324
MIRT499650	hsa-let-7i-5p	PAR-CLIP	24398324
MIRT499649	hsa-miR-4458	PAR-CLIP	24398324
MIRT499648	hsa-miR-4500	PAR-CLIP	24398324
MIRT499647	hsa-miR-98-5p	PAR-CLIP	24398324
MIRT499646	hsa-miR-202-3p	PAR-CLIP	24398324
MIRT499645	hsa-miR-4650-3p	PAR-CLIP	24398324
MIRT499644	hsa-miR-202-5p	PAR-CLIP	24398324
MIRT1332075	hsa-miR-1208	CLIP-seq
MIRT1332076	hsa-miR-1293	CLIP-seq
MIRT1332077	hsa-miR-130a	CLIP-seq
MIRT1332078	hsa-miR-130b	CLIP-seq
MIRT1332079	hsa-miR-1324	CLIP-seq
MIRT1332080	hsa-miR-301a	CLIP-seq
MIRT1332081	hsa-miR-301b	CLIP-seq
MIRT1332082	hsa-miR-3182	CLIP-seq
MIRT1332083	hsa-miR-3189-3p	CLIP-seq
MIRT1332084	hsa-miR-34c-3p	CLIP-seq
MIRT1332085	hsa-miR-3617	CLIP-seq
MIRT1332086	hsa-miR-3666	CLIP-seq
MIRT1332087	hsa-miR-4265	CLIP-seq
MIRT1332088	hsa-miR-4295	CLIP-seq
MIRT1332089	hsa-miR-4296	CLIP-seq
MIRT1332090	hsa-miR-4322	CLIP-seq
MIRT1332091	hsa-miR-4326	CLIP-seq
MIRT1332092	hsa-miR-4435	CLIP-seq
MIRT1332093	hsa-miR-4483	CLIP-seq
MIRT1332094	hsa-miR-454	CLIP-seq
MIRT1332095	hsa-miR-4643	CLIP-seq
MIRT1332096	hsa-miR-4652-3p	CLIP-seq
MIRT1332097	hsa-miR-466	CLIP-seq
MIRT1332098	hsa-miR-4671-3p	CLIP-seq
MIRT1332099	hsa-miR-4708-3p	CLIP-seq
MIRT1332100	hsa-miR-4717-5p	CLIP-seq
MIRT1332101	hsa-miR-4753-5p	CLIP-seq
MIRT1332102	hsa-miR-4789-3p	CLIP-seq
MIRT1332103	hsa-miR-502-5p	CLIP-seq
MIRT1332104	hsa-miR-512-3p	CLIP-seq
MIRT1332105	hsa-miR-641	CLIP-seq
MIRT2098130	hsa-let-7a	CLIP-seq
MIRT2098131	hsa-let-7b	CLIP-seq
MIRT2098132	hsa-let-7c	CLIP-seq
MIRT2098133	hsa-let-7d	CLIP-seq
MIRT2098134	hsa-let-7e	CLIP-seq
MIRT2098135	hsa-let-7f	CLIP-seq
MIRT2098136	hsa-let-7g	CLIP-seq
MIRT2098137	hsa-let-7i	CLIP-seq
MIRT1332075	hsa-miR-1208	CLIP-seq
MIRT2098138	hsa-miR-186	CLIP-seq
MIRT2098139	hsa-miR-202	CLIP-seq
MIRT2098140	hsa-miR-3120-5p	CLIP-seq
MIRT2098141	hsa-miR-3135b	CLIP-seq
MIRT2098142	hsa-miR-3137	CLIP-seq
MIRT1332084	hsa-miR-34c-3p	CLIP-seq
MIRT2098143	hsa-miR-3664-5p	CLIP-seq
MIRT2098144	hsa-miR-3686	CLIP-seq
MIRT2098145	hsa-miR-3915	CLIP-seq
MIRT2098146	hsa-miR-3927	CLIP-seq
MIRT2098147	hsa-miR-4522	CLIP-seq
MIRT1332095	hsa-miR-4643	CLIP-seq
MIRT1332096	hsa-miR-4652-3p	CLIP-seq
MIRT1332097	hsa-miR-466	CLIP-seq
MIRT2098148	hsa-miR-4778-3p	CLIP-seq
MIRT1332102	hsa-miR-4789-3p	CLIP-seq
MIRT2098149	hsa-miR-98	CLIP-seq
MIRT1332075	hsa-miR-1208	CLIP-seq
MIRT2322874	hsa-miR-129-3p	CLIP-seq
MIRT2322875	hsa-miR-3121-3p	CLIP-seq
MIRT1332084	hsa-miR-34c-3p	CLIP-seq
MIRT2322876	hsa-miR-3651	CLIP-seq
MIRT2322877	hsa-miR-3908	CLIP-seq
MIRT2322878	hsa-miR-3942-5p	CLIP-seq
MIRT1332095	hsa-miR-4643	CLIP-seq
MIRT1332097	hsa-miR-466	CLIP-seq
MIRT2322879	hsa-miR-4687-5p	CLIP-seq
MIRT2322880	hsa-miR-4703-5p	CLIP-seq
MIRT2322881	hsa-miR-4712-5p	CLIP-seq
MIRT2322882	hsa-miR-4766-3p	CLIP-seq
MIRT1332102	hsa-miR-4789-3p	CLIP-seq
MIRT2322883	hsa-miR-520d-5p	CLIP-seq
MIRT2322884	hsa-miR-524-5p	CLIP-seq
MIRT2322885	hsa-miR-770-5p	CLIP-seq

Show/Hide all (5)

GO ID	Ontology	Definition	Evidence
GO:0006694	Process	Steroid biosynthetic process	IEA
GO:0016020	Component	Membrane	IEA
GO:0016491	Function	Oxidoreductase activity	IEA
GO:0016616	Function	Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IBA
GO:0016616	Function	Oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA

MIM	HGNC	e!Ensembl
616164	29834	ENSG00000184860

Q8WUS8

Protein name

Short-chain dehydrogenase/reductase family 42E member 1 (EC 1.1.1.-)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01073	3Beta_HSD	12 → 284	3-beta hydroxysteroid dehydrogenase/isomerase family	Family

Sequence

MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRH
LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY
TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRT
CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR
ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI
LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSG
SRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL

Sequence length

393

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
LIVER CIRRHOSIS, EXPERIMENTAL	—	CTD	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SPONDYLOMETAPHYSEAL DYSPLASIA, PAGNAMENTA TYPE	—	Disgenet	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Colorectal Neoplasms	Associate	21829702	★★★★★ ★☆☆☆☆ Found in Text Mining only
Down Syndrome	Associate	39596121	★★★★★ ★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	40756515	★★★★★ ★☆☆☆☆ Found in Text Mining only
Pregnancy Ectopic	Associate	34215268	★★★★★ ★☆☆☆☆ Found in Text Mining only
Vitamin D Deficiency	Associate	40756515	★★★★★ ★☆☆☆☆ Found in Text Mining only

SDR42E1 (short chain dehydrogenase/reductase family 42E, member 1)