Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9351
Gene name Gene Name - the full gene name approved by the HGNC.	NHERF family PDZ scaffold protein 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NHERF2
Synonyms (NCBI Gene) Gene synonyms aliases	E3KARP, NHE3RF2, NHERF-2, OCTS2, SIP-1, SIP1, SLC9A3R2, TKA-1
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16p13.3

Show/Hide all(296)

miRTarBase ID	miRNA	Experiments	Reference
MIRT005146	hsa-miR-30a-5p	pSILAC	18668040
MIRT005146	hsa-miR-30a-5p	pSILAC	18668040
MIRT020575	hsa-miR-155-5p	Proteomics	18668040
MIRT005146	hsa-miR-30a-5p	Proteomics;Other	18668040
MIRT045974	hsa-miR-125b-5p	CLASH	23622248
MIRT618018	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT618017	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618016	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618009	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT618007	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT618006	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT618005	hsa-miR-4711-3p	HITS-CLIP	23824327
MIRT618004	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618003	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT618002	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT618018	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT618017	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618016	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618015	hsa-miR-146a-3p	HITS-CLIP	23824327
MIRT618014	hsa-miR-301a-5p	HITS-CLIP	23824327
MIRT618013	hsa-miR-301b-5p	HITS-CLIP	23824327
MIRT618012	hsa-miR-3921	HITS-CLIP	23824327
MIRT618011	hsa-miR-4653-5p	HITS-CLIP	23824327
MIRT618010	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT618009	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT618008	hsa-miR-4522	HITS-CLIP	23824327
MIRT618007	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT618006	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT618005	hsa-miR-4711-3p	HITS-CLIP	23824327
MIRT618004	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618003	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT618002	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT486846	hsa-miR-6827-5p	PAR-CLIP	23592263
MIRT486845	hsa-miR-1343-5p	PAR-CLIP	23592263
MIRT486844	hsa-miR-939-5p	PAR-CLIP	23592263
MIRT486843	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT486842	hsa-miR-5698	PAR-CLIP	23592263
MIRT486841	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT486840	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT618018	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT618017	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618016	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618009	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT618007	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT618006	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT618005	hsa-miR-4711-3p	HITS-CLIP	23824327
MIRT618004	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618003	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT618002	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT618018	hsa-miR-6812-3p	HITS-CLIP	23824327
MIRT618017	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT618016	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT618015	hsa-miR-146a-3p	HITS-CLIP	23824327
MIRT618014	hsa-miR-301a-5p	HITS-CLIP	23824327
MIRT618013	hsa-miR-301b-5p	HITS-CLIP	23824327
MIRT618012	hsa-miR-3921	HITS-CLIP	23824327
MIRT618011	hsa-miR-4653-5p	HITS-CLIP	23824327
MIRT618010	hsa-miR-345-5p	HITS-CLIP	23824327
MIRT618009	hsa-miR-3120-5p	HITS-CLIP	23824327
MIRT618008	hsa-miR-4522	HITS-CLIP	23824327
MIRT618007	hsa-miR-6895-3p	HITS-CLIP	23824327
MIRT618006	hsa-miR-593-3p	HITS-CLIP	23824327
MIRT618005	hsa-miR-4711-3p	HITS-CLIP	23824327
MIRT618004	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT618003	hsa-miR-6888-3p	HITS-CLIP	23824327
MIRT618002	hsa-miR-6818-3p	HITS-CLIP	23824327
MIRT486846	hsa-miR-6827-5p	PAR-CLIP	23592263
MIRT486845	hsa-miR-1343-5p	PAR-CLIP	23592263
MIRT486844	hsa-miR-939-5p	PAR-CLIP	23592263
MIRT486843	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT486842	hsa-miR-5698	PAR-CLIP	23592263
MIRT486841	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT486840	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT1368789	hsa-miR-1207-5p	CLIP-seq
MIRT1368790	hsa-miR-1270	CLIP-seq
MIRT1368791	hsa-miR-1275	CLIP-seq
MIRT1368792	hsa-miR-1303	CLIP-seq
MIRT1368793	hsa-miR-137	CLIP-seq
MIRT1368794	hsa-miR-147	CLIP-seq
MIRT1368795	hsa-miR-15a	CLIP-seq
MIRT1368796	hsa-miR-15b	CLIP-seq
MIRT1368797	hsa-miR-16	CLIP-seq
MIRT1368798	hsa-miR-1909	CLIP-seq
MIRT1368799	hsa-miR-195	CLIP-seq
MIRT1368800	hsa-miR-214	CLIP-seq
MIRT1368801	hsa-miR-2278	CLIP-seq
MIRT1368802	hsa-miR-2392	CLIP-seq
MIRT1368803	hsa-miR-2467-5p	CLIP-seq
MIRT1368804	hsa-miR-25	CLIP-seq
MIRT1368805	hsa-miR-3064-3p	CLIP-seq
MIRT1368806	hsa-miR-3135b	CLIP-seq
MIRT1368807	hsa-miR-3136-3p	CLIP-seq
MIRT1368808	hsa-miR-3148	CLIP-seq
MIRT1368809	hsa-miR-3179	CLIP-seq
MIRT1368810	hsa-miR-3187-3p	CLIP-seq
MIRT1368811	hsa-miR-3188	CLIP-seq
MIRT1368812	hsa-miR-32	CLIP-seq
MIRT1368813	hsa-miR-3202	CLIP-seq
MIRT1368814	hsa-miR-361-3p	CLIP-seq
MIRT1368815	hsa-miR-3619-5p	CLIP-seq
MIRT1368816	hsa-miR-363	CLIP-seq
MIRT1368817	hsa-miR-367	CLIP-seq
MIRT1368818	hsa-miR-3911	CLIP-seq
MIRT1368819	hsa-miR-3929	CLIP-seq
MIRT1368820	hsa-miR-3975	CLIP-seq
MIRT1368821	hsa-miR-3978	CLIP-seq
MIRT1368822	hsa-miR-424	CLIP-seq
MIRT1368823	hsa-miR-4252	CLIP-seq
MIRT1368824	hsa-miR-4271	CLIP-seq
MIRT1368825	hsa-miR-4283	CLIP-seq
MIRT1368826	hsa-miR-4284	CLIP-seq
MIRT1368827	hsa-miR-4291	CLIP-seq
MIRT1368828	hsa-miR-4300	CLIP-seq
MIRT1368829	hsa-miR-4419b	CLIP-seq
MIRT1368830	hsa-miR-4435	CLIP-seq
MIRT1368831	hsa-miR-4437	CLIP-seq
MIRT1368832	hsa-miR-4456	CLIP-seq
MIRT1368833	hsa-miR-4478	CLIP-seq
MIRT1368834	hsa-miR-4487	CLIP-seq
MIRT1368835	hsa-miR-4488	CLIP-seq
MIRT1368836	hsa-miR-4505	CLIP-seq
MIRT1368837	hsa-miR-4508	CLIP-seq
MIRT1368838	hsa-miR-4525	CLIP-seq
MIRT1368839	hsa-miR-4633-3p	CLIP-seq
MIRT1368840	hsa-miR-4646-5p	CLIP-seq
MIRT1368841	hsa-miR-4649-3p	CLIP-seq
MIRT1368842	hsa-miR-4655-5p	CLIP-seq
MIRT1368843	hsa-miR-4665-5p	CLIP-seq
MIRT1368844	hsa-miR-4683	CLIP-seq
MIRT1368845	hsa-miR-4688	CLIP-seq
MIRT1368846	hsa-miR-4690-5p	CLIP-seq
MIRT1368847	hsa-miR-4697-5p	CLIP-seq
MIRT1368848	hsa-miR-4701-5p	CLIP-seq
MIRT1368849	hsa-miR-4704-3p	CLIP-seq
MIRT1368850	hsa-miR-4707-5p	CLIP-seq
MIRT1368851	hsa-miR-4712-5p	CLIP-seq
MIRT1368852	hsa-miR-4716-3p	CLIP-seq
MIRT1368853	hsa-miR-4719	CLIP-seq
MIRT1368854	hsa-miR-4725-3p	CLIP-seq
MIRT1368855	hsa-miR-4728-5p	CLIP-seq
MIRT1368856	hsa-miR-4731-5p	CLIP-seq
MIRT1368857	hsa-miR-4747-5p	CLIP-seq
MIRT1368858	hsa-miR-4763-3p	CLIP-seq
MIRT1368859	hsa-miR-485-5p	CLIP-seq
MIRT1368860	hsa-miR-486-3p	CLIP-seq
MIRT1368861	hsa-miR-497	CLIP-seq
MIRT1368862	hsa-miR-541	CLIP-seq
MIRT1368863	hsa-miR-545	CLIP-seq
MIRT1368864	hsa-miR-548p	CLIP-seq
MIRT1368865	hsa-miR-548s	CLIP-seq
MIRT1368866	hsa-miR-588	CLIP-seq
MIRT1368867	hsa-miR-593	CLIP-seq
MIRT1368868	hsa-miR-619	CLIP-seq
MIRT1368869	hsa-miR-620	CLIP-seq
MIRT1368870	hsa-miR-625	CLIP-seq
MIRT1368871	hsa-miR-637	CLIP-seq
MIRT1368872	hsa-miR-644	CLIP-seq
MIRT1368873	hsa-miR-654-5p	CLIP-seq
MIRT1368874	hsa-miR-761	CLIP-seq
MIRT1368875	hsa-miR-770-5p	CLIP-seq
MIRT1368876	hsa-miR-920	CLIP-seq
MIRT1368877	hsa-miR-922	CLIP-seq
MIRT1368878	hsa-miR-92a	CLIP-seq
MIRT1368879	hsa-miR-92b	CLIP-seq
MIRT1368880	hsa-miR-939	CLIP-seq
MIRT1368881	hsa-miR-944	CLIP-seq
MIRT1368793	hsa-miR-137	CLIP-seq
MIRT1368882	hsa-miR-1908	CLIP-seq
MIRT1368883	hsa-miR-2467-3p	CLIP-seq
MIRT1368804	hsa-miR-25	CLIP-seq
MIRT1368884	hsa-miR-3180	CLIP-seq
MIRT1368885	hsa-miR-3180-3p	CLIP-seq
MIRT1368886	hsa-miR-3184	CLIP-seq
MIRT1368810	hsa-miR-3187-3p	CLIP-seq
MIRT1368887	hsa-miR-3196	CLIP-seq
MIRT1368812	hsa-miR-32	CLIP-seq
MIRT1368816	hsa-miR-363	CLIP-seq
MIRT1368817	hsa-miR-367	CLIP-seq
MIRT1368888	hsa-miR-3678-3p	CLIP-seq
MIRT1368889	hsa-miR-3919	CLIP-seq
MIRT1368890	hsa-miR-423-5p	CLIP-seq
MIRT1368823	hsa-miR-4252	CLIP-seq
MIRT1368830	hsa-miR-4435	CLIP-seq
MIRT1368891	hsa-miR-4464	CLIP-seq
MIRT1368835	hsa-miR-4488	CLIP-seq
MIRT1368840	hsa-miR-4646-5p	CLIP-seq
MIRT1368892	hsa-miR-4663	CLIP-seq
MIRT1368847	hsa-miR-4697-5p	CLIP-seq
MIRT1368848	hsa-miR-4701-5p	CLIP-seq
MIRT1368893	hsa-miR-4706	CLIP-seq
MIRT1368855	hsa-miR-4728-5p	CLIP-seq
MIRT1368857	hsa-miR-4747-5p	CLIP-seq
MIRT1368894	hsa-miR-4748	CLIP-seq
MIRT1368895	hsa-miR-4749-5p	CLIP-seq
MIRT1368865	hsa-miR-548s	CLIP-seq
MIRT1368866	hsa-miR-588	CLIP-seq
MIRT1368867	hsa-miR-593	CLIP-seq
MIRT1368896	hsa-miR-663	CLIP-seq
MIRT1368878	hsa-miR-92a	CLIP-seq
MIRT1368879	hsa-miR-92b	CLIP-seq
MIRT1368881	hsa-miR-944	CLIP-seq
MIRT1368810	hsa-miR-3187-3p	CLIP-seq
MIRT1368823	hsa-miR-4252	CLIP-seq
MIRT1368830	hsa-miR-4435	CLIP-seq
MIRT1368840	hsa-miR-4646-5p	CLIP-seq
MIRT1368848	hsa-miR-4701-5p	CLIP-seq
MIRT1368857	hsa-miR-4747-5p	CLIP-seq
MIRT1368865	hsa-miR-548s	CLIP-seq
MIRT1368866	hsa-miR-588	CLIP-seq
MIRT1368803	hsa-miR-2467-5p	CLIP-seq
MIRT1368810	hsa-miR-3187-3p	CLIP-seq
MIRT1368811	hsa-miR-3188	CLIP-seq
MIRT1368820	hsa-miR-3975	CLIP-seq
MIRT1368823	hsa-miR-4252	CLIP-seq
MIRT1368830	hsa-miR-4435	CLIP-seq
MIRT1368840	hsa-miR-4646-5p	CLIP-seq
MIRT1368848	hsa-miR-4701-5p	CLIP-seq
MIRT1368855	hsa-miR-4728-5p	CLIP-seq
MIRT1368857	hsa-miR-4747-5p	CLIP-seq
MIRT1368859	hsa-miR-485-5p	CLIP-seq
MIRT1368865	hsa-miR-548s	CLIP-seq
MIRT1368866	hsa-miR-588	CLIP-seq
MIRT1368867	hsa-miR-593	CLIP-seq
MIRT1368880	hsa-miR-939	CLIP-seq
MIRT1368789	hsa-miR-1207-5p	CLIP-seq
MIRT1368791	hsa-miR-1275	CLIP-seq
MIRT2332804	hsa-miR-1285	CLIP-seq
MIRT2332805	hsa-miR-1286	CLIP-seq
MIRT1368798	hsa-miR-1909	CLIP-seq
MIRT1368802	hsa-miR-2392	CLIP-seq
MIRT1368803	hsa-miR-2467-5p	CLIP-seq
MIRT1368810	hsa-miR-3187-3p	CLIP-seq
MIRT2332806	hsa-miR-3187-5p	CLIP-seq
MIRT1368811	hsa-miR-3188	CLIP-seq
MIRT2332807	hsa-miR-378g	CLIP-seq
MIRT2332808	hsa-miR-3925-3p	CLIP-seq
MIRT1368819	hsa-miR-3929	CLIP-seq
MIRT1368820	hsa-miR-3975	CLIP-seq
MIRT1368823	hsa-miR-4252	CLIP-seq
MIRT1368825	hsa-miR-4283	CLIP-seq
MIRT1368826	hsa-miR-4284	CLIP-seq
MIRT1368828	hsa-miR-4300	CLIP-seq
MIRT2332809	hsa-miR-4314	CLIP-seq
MIRT1368829	hsa-miR-4419b	CLIP-seq
MIRT1368830	hsa-miR-4435	CLIP-seq
MIRT1368831	hsa-miR-4437	CLIP-seq
MIRT1368832	hsa-miR-4456	CLIP-seq
MIRT1368833	hsa-miR-4478	CLIP-seq
MIRT2332810	hsa-miR-4486	CLIP-seq
MIRT1368835	hsa-miR-4488	CLIP-seq
MIRT2332811	hsa-miR-4489	CLIP-seq
MIRT2332812	hsa-miR-4492	CLIP-seq
MIRT2332813	hsa-miR-4498	CLIP-seq
MIRT1368836	hsa-miR-4505	CLIP-seq
MIRT1368837	hsa-miR-4508	CLIP-seq
MIRT1368838	hsa-miR-4525	CLIP-seq
MIRT2332814	hsa-miR-455-3p	CLIP-seq
MIRT1368840	hsa-miR-4646-5p	CLIP-seq
MIRT1368841	hsa-miR-4649-3p	CLIP-seq
MIRT1368842	hsa-miR-4655-5p	CLIP-seq
MIRT2332815	hsa-miR-4656	CLIP-seq
MIRT1368843	hsa-miR-4665-5p	CLIP-seq
MIRT1368845	hsa-miR-4688	CLIP-seq
MIRT1368847	hsa-miR-4697-5p	CLIP-seq
MIRT1368848	hsa-miR-4701-5p	CLIP-seq
MIRT1368856	hsa-miR-4731-5p	CLIP-seq
MIRT2332816	hsa-miR-4736	CLIP-seq
MIRT1368857	hsa-miR-4747-5p	CLIP-seq
MIRT1368858	hsa-miR-4763-3p	CLIP-seq
MIRT1368859	hsa-miR-485-5p	CLIP-seq
MIRT1368860	hsa-miR-486-3p	CLIP-seq
MIRT1368862	hsa-miR-541	CLIP-seq
MIRT1368865	hsa-miR-548s	CLIP-seq
MIRT1368866	hsa-miR-588	CLIP-seq
MIRT2332817	hsa-miR-612	CLIP-seq
MIRT1368870	hsa-miR-625	CLIP-seq
MIRT1368871	hsa-miR-637	CLIP-seq
MIRT1368873	hsa-miR-654-5p	CLIP-seq
MIRT2332818	hsa-miR-762	CLIP-seq
MIRT1368876	hsa-miR-920	CLIP-seq
MIRT1368880	hsa-miR-939	CLIP-seq
MIRT1368810	hsa-miR-3187-3p	CLIP-seq
MIRT1368823	hsa-miR-4252	CLIP-seq
MIRT1368830	hsa-miR-4435	CLIP-seq
MIRT1368840	hsa-miR-4646-5p	CLIP-seq
MIRT1368848	hsa-miR-4701-5p	CLIP-seq
MIRT1368857	hsa-miR-4747-5p	CLIP-seq
MIRT1368865	hsa-miR-548s	CLIP-seq
MIRT1368866	hsa-miR-588	CLIP-seq
MIRT2459933	hsa-miR-1915	CLIP-seq
MIRT2459934	hsa-miR-3156-3p	CLIP-seq
MIRT2459935	hsa-miR-3664-3p	CLIP-seq
MIRT2459936	hsa-miR-4301	CLIP-seq
MIRT2459937	hsa-miR-4726-3p	CLIP-seq
MIRT2459938	hsa-miR-510	CLIP-seq
MIRT2459939	hsa-miR-532-3p	CLIP-seq

Show/Hide all(25)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005102	Function	Signaling receptor binding	IBA
GO:0005102	Function	Signaling receptor binding	IPI	16456542
GO:0005515	Function	Protein binding	IPI	9054412, 11285285, 11786550, 12369822, 12444019, 15523054, 16166090, 16203867, 16456542, 16615918, 17110338, 17242191, 17979986, 19027007, 19555689, 20618342, 22587461, 24255178, 25519916, 26618866, 27018634, 27173435, 28360110, 31324722, 32296183, 33961781, 35271311, 36012204
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	TAS	9054412
GO:0005886	Component	Plasma membrane	IDA	11786550
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	9748260
GO:0005925	Component	Focal adhesion	HDA	21423176
GO:0008013	Function	Beta-catenin binding	IEA
GO:0008013	Function	Beta-catenin binding	IPI	17242191
GO:0012505	Component	Endomembrane system	IEA
GO:0016020	Component	Membrane	IEA
GO:0016324	Component	Apical plasma membrane	IBA
GO:0016324	Component	Apical plasma membrane	IEA
GO:0019902	Function	Phosphatase binding	IPI	16456542
GO:0031799	Function	Type 2 metabotropic glutamate receptor binding	ISS
GO:0031800	Function	Type 3 metabotropic glutamate receptor binding	ISS
GO:0042802	Function	Identical protein binding	IPI	22587461
GO:0043495	Function	Protein-membrane adaptor activity	IBA
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0060090	Function	Molecular adaptor activity	IEA
GO:0065003	Process	Protein-containing complex assembly	TAS	9748260
GO:0070062	Component	Extracellular exosome	HDA	19056867, 23533145
GO:0072659	Process	Protein localization to plasma membrane	IBA

MIM	HGNC	e!Ensembl
606553	11076	ENSG00000065054

Protein

UniProt ID

Q15599

Protein name

Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (NHERF-2) (NHE3 kinase A regulatory protein E3KARP) (SRY-interacting protein 1) (SIP-1) (Sodium-hydrogen exchanger regulatory factor 2) (Solute carrier family 9 isoform A3 regulatory factor 2) (Tyrosine kina

Protein function

Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylatio

PDB

2D11 , 2HE4 , 2OCS , 4P0C

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00595	PDZ	12 → 88	PDZ domain	Domain
PF00595	PDZ	151 → 228	PDZ domain	Domain
PF09007	EBP50_C	232 → 278	EBP50, C-terminal	Domain
PF09007	EBP50_C	261 → 337	EBP50, C-terminal	Domain

Tissue specificity

TISSUE SPECIFICITY: Widely expressed. {ECO:0000269|PubMed:9054412, ECO:0000269|PubMed:9096337}.

Sequence

MAAPEPLRPRLCRLVRGEQGYGFHLHGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVEVN
GVNVEGETHHQVVQRIKAVEGQTRLLVVDQETDEELRRRQLTCTEEMAQRGLPPAHDPWE
PKPDWAHTGSHSSEAGKKDVSGPLRELRPRLCHLRKGPQGYGFNLHSDKSRPGQYIRSVD
PGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLR
VTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGL
HLSPTAAEAKEKARAMRVNKRAPQMDWNRKREIFSNF

Sequence length

337

Interactions

View interactions

	KEGG
	Aldosterone-regulated sodium reabsorption

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Metabolic Syndrome	Metabolic syndrome	N/A	N/A	GWAS

NHERF2 (NHERF family PDZ scaffold protein 2)