Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	9340
Gene name	Glucagon like peptide 2 receptor
Gene symbol	GLP2R
Synonyms (NCBI Gene)	-
Chromosome	17
Chromosome location	17p13.1
Summary	This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomita

157

Show/Hide all (157)

miRTarBase ID	miRNA	Experiments	Reference
MIRT696128	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT696127	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT696126	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT696125	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT696124	hsa-miR-340-3p	HITS-CLIP	23313552
MIRT696123	hsa-miR-6827-3p	HITS-CLIP	23313552
MIRT696122	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT696121	hsa-miR-3926	HITS-CLIP	23313552
MIRT696120	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT696119	hsa-miR-548s	HITS-CLIP	23313552
MIRT682518	hsa-miR-15a-5p	HITS-CLIP	23706177
MIRT682517	hsa-miR-15b-5p	HITS-CLIP	23706177
MIRT682516	hsa-miR-16-5p	HITS-CLIP	23706177
MIRT682515	hsa-miR-195-5p	HITS-CLIP	23706177
MIRT682514	hsa-miR-424-5p	HITS-CLIP	23706177
MIRT682513	hsa-miR-497-5p	HITS-CLIP	23706177
MIRT682512	hsa-miR-6838-5p	HITS-CLIP	23706177
MIRT682511	hsa-miR-503-5p	HITS-CLIP	23706177
MIRT682510	hsa-miR-646	HITS-CLIP	23706177
MIRT682509	hsa-miR-4310	HITS-CLIP	23706177
MIRT682508	hsa-miR-7157-5p	HITS-CLIP	23706177
MIRT682507	hsa-miR-103a-3p	HITS-CLIP	23706177
MIRT682506	hsa-miR-107	HITS-CLIP	23706177
MIRT682505	hsa-miR-4524a-5p	HITS-CLIP	23706177
MIRT682504	hsa-miR-4524b-5p	HITS-CLIP	23706177
MIRT682503	hsa-miR-4662a-5p	HITS-CLIP	23706177
MIRT682502	hsa-miR-513b-5p	HITS-CLIP	23706177
MIRT629966	hsa-miR-524-3p	HITS-CLIP	23824327
MIRT629965	hsa-miR-525-3p	HITS-CLIP	23824327
MIRT629964	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT629963	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT629962	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT629961	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT629960	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT629959	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT629958	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT629957	hsa-miR-7977	HITS-CLIP	23824327
MIRT629956	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT629955	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT629954	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT629953	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT629952	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT629951	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT629950	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT629949	hsa-miR-3689c	HITS-CLIP	23824327
MIRT629948	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT629947	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT629946	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT629945	hsa-miR-3122	HITS-CLIP	23824327
MIRT629944	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT629943	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT629942	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT531905	hsa-miR-5692a	PAR-CLIP	22012620
MIRT531904	hsa-miR-4712-3p	PAR-CLIP	22012620
MIRT531903	hsa-miR-139-5p	PAR-CLIP	22012620
MIRT531902	hsa-miR-548aw	PAR-CLIP	22012620
MIRT531901	hsa-miR-518a-5p	PAR-CLIP	22012620
MIRT531900	hsa-miR-527	PAR-CLIP	22012620
MIRT531899	hsa-miR-450b-5p	PAR-CLIP	22012620
MIRT450446	hsa-miR-5582-5p	PAR-CLIP	22100165
MIRT450445	hsa-miR-4269	PAR-CLIP	22100165
MIRT450444	hsa-miR-6715b-5p	PAR-CLIP	22100165
MIRT450443	hsa-miR-3913-3p	PAR-CLIP	22100165
MIRT450442	hsa-miR-489-3p	PAR-CLIP	22100165
MIRT450441	hsa-miR-1273e	PAR-CLIP	22100165
MIRT450441	hsa-miR-1273e	PAR-CLIP	27292025
MIRT629953	hsa-miR-1273h-5p	PAR-CLIP	27292025
MIRT629953	hsa-miR-1273h-5p	PAR-CLIP	27292025
MIRT629962	hsa-miR-149-3p	PAR-CLIP	27292025
MIRT629962	hsa-miR-149-3p	PAR-CLIP	27292025
MIRT629952	hsa-miR-30b-3p	PAR-CLIP	27292025
MIRT629952	hsa-miR-30b-3p	PAR-CLIP	27292025
MIRT629951	hsa-miR-3689a-3p	PAR-CLIP	27292025
MIRT629951	hsa-miR-3689a-3p	PAR-CLIP	27292025
MIRT629950	hsa-miR-3689b-3p	PAR-CLIP	27292025
MIRT629950	hsa-miR-3689b-3p	PAR-CLIP	27292025
MIRT629949	hsa-miR-3689c	PAR-CLIP	27292025
MIRT629949	hsa-miR-3689c	PAR-CLIP	27292025
MIRT629961	hsa-miR-4728-5p	PAR-CLIP	27292025
MIRT629961	hsa-miR-4728-5p	PAR-CLIP	27292025
MIRT629948	hsa-miR-6779-5p	PAR-CLIP	27292025
MIRT629948	hsa-miR-6779-5p	PAR-CLIP	27292025
MIRT629947	hsa-miR-6780a-5p	PAR-CLIP	27292025
MIRT629947	hsa-miR-6780a-5p	PAR-CLIP	27292025
MIRT629960	hsa-miR-6785-5p	PAR-CLIP	27292025
MIRT629960	hsa-miR-6785-5p	PAR-CLIP	27292025
MIRT629958	hsa-miR-6799-5p	PAR-CLIP	27292025
MIRT629958	hsa-miR-6799-5p	PAR-CLIP	27292025
MIRT629959	hsa-miR-6883-5p	PAR-CLIP	27292025
MIRT629959	hsa-miR-6883-5p	PAR-CLIP	27292025
MIRT629963	hsa-miR-7106-5p	PAR-CLIP	27292025
MIRT629963	hsa-miR-7106-5p	PAR-CLIP	27292025
MIRT696128	hsa-miR-548c-3p	HITS-CLIP	23313552
MIRT696127	hsa-miR-6771-3p	HITS-CLIP	23313552
MIRT696126	hsa-miR-3613-3p	HITS-CLIP	23313552
MIRT696125	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT696124	hsa-miR-340-3p	HITS-CLIP	23313552
MIRT696123	hsa-miR-6827-3p	HITS-CLIP	23313552
MIRT696122	hsa-miR-3190-5p	HITS-CLIP	23313552
MIRT696121	hsa-miR-3926	HITS-CLIP	23313552
MIRT696120	hsa-miR-4684-5p	HITS-CLIP	23313552
MIRT696119	hsa-miR-548s	HITS-CLIP	23313552
MIRT682518	hsa-miR-15a-5p	HITS-CLIP	23706177
MIRT682517	hsa-miR-15b-5p	HITS-CLIP	23706177
MIRT682516	hsa-miR-16-5p	HITS-CLIP	23706177
MIRT682515	hsa-miR-195-5p	HITS-CLIP	23706177
MIRT682514	hsa-miR-424-5p	HITS-CLIP	23706177
MIRT682513	hsa-miR-497-5p	HITS-CLIP	23706177
MIRT682512	hsa-miR-6838-5p	HITS-CLIP	23706177
MIRT682511	hsa-miR-503-5p	HITS-CLIP	23706177
MIRT682510	hsa-miR-646	HITS-CLIP	23706177
MIRT682509	hsa-miR-4310	HITS-CLIP	23706177
MIRT682508	hsa-miR-7157-5p	HITS-CLIP	23706177
MIRT682507	hsa-miR-103a-3p	HITS-CLIP	23706177
MIRT682506	hsa-miR-107	HITS-CLIP	23706177
MIRT682505	hsa-miR-4524a-5p	HITS-CLIP	23706177
MIRT682504	hsa-miR-4524b-5p	HITS-CLIP	23706177
MIRT682503	hsa-miR-4662a-5p	HITS-CLIP	23706177
MIRT682502	hsa-miR-513b-5p	HITS-CLIP	23706177
MIRT629966	hsa-miR-524-3p	HITS-CLIP	23824327
MIRT629965	hsa-miR-525-3p	HITS-CLIP	23824327
MIRT629964	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT629963	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT629962	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT629961	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT629960	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT629959	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT629958	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT629957	hsa-miR-7977	HITS-CLIP	23824327
MIRT629956	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT629955	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT629954	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT629953	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT629952	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT629951	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT629950	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT629949	hsa-miR-3689c	HITS-CLIP	23824327
MIRT629948	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT629947	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT629946	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT629945	hsa-miR-3122	HITS-CLIP	23824327
MIRT629944	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT629943	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT629942	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT531905	hsa-miR-5692a	PAR-CLIP	22012620
MIRT531904	hsa-miR-4712-3p	PAR-CLIP	22012620
MIRT531903	hsa-miR-139-5p	PAR-CLIP	22012620
MIRT531902	hsa-miR-548aw	PAR-CLIP	22012620
MIRT531901	hsa-miR-518a-5p	PAR-CLIP	22012620
MIRT531900	hsa-miR-527	PAR-CLIP	22012620
MIRT531899	hsa-miR-450b-5p	PAR-CLIP	22012620
MIRT450446	hsa-miR-5582-5p	PAR-CLIP	22100165
MIRT450445	hsa-miR-4269	PAR-CLIP	22100165
MIRT450444	hsa-miR-6715b-5p	PAR-CLIP	22100165
MIRT450443	hsa-miR-3913-3p	PAR-CLIP	22100165
MIRT450442	hsa-miR-489-3p	PAR-CLIP	22100165
MIRT450441	hsa-miR-1273e	PAR-CLIP	22100165

Show/Hide all (19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004888	Function	Transmembrane signaling receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	IEA
GO:0004930	Function	G protein-coupled receptor activity	TAS	9990065
GO:0004967	Function	Glucagon receptor activity	IBA
GO:0004967	Function	Glucagon receptor activity	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS	9990065
GO:0007165	Process	Signal transduction	IEA
GO:0007166	Process	Cell surface receptor signaling pathway	IEA
GO:0007186	Process	G protein-coupled receptor signaling pathway	IEA
GO:0007188	Process	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA
GO:0007188	Process	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IEA
GO:0007188	Process	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway	TAS	9990065
GO:0008284	Process	Positive regulation of cell population proliferation	TAS	9990065
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	9990065
GO:0017046	Function	Peptide hormone binding	IBA
GO:0071377	Process	Cellular response to glucagon stimulus	IEA

MIM	HGNC	e!Ensembl
603659	4325	ENSG00000065325

O95838

Protein name

Glucagon-like peptide 2 receptor (GLP-2 receptor) (GLP-2-R) (GLP-2R)

Protein function

This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

PDB

7D68

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF02793	HRM	93 → 162	Hormone receptor domain	Family
PF00002	7tm_2	175 → 432	7 transmembrane receptor (Secretin family)	Family

Sequence

MKLGSSRAGPGRGSAGLLPGVHELPMGIPAPWGTSPLSFHRKCSLWAPGRPFLTLVLLVS
IKQVTGSLLEETTRKWAQYKQACLRDLLKEPSGIFCNGTFDQYVCWPHSSPGNVSVPCPS
YLPWWSEESSGRAYRHCLAQGTWQTIENATDIWQDDSECSENHSFKQNVDRYALLSTLQL
MYTVGYSFSLISLFLALTLLLFLRKLHCTRNYIHMNLFASFILRTLAVLVKDVVFYNSYS
KRPDNENGWMSYLSEMSTSCRSVQVLLHYFVGANYLWLLVEGLYLHTLLEPTVLPERRLW
PRYLLLGWAFPVLFVVPWGFARAHLENTGCWTTNGNKKIWWIIRGPMMLCVTVNFFIFLK
ILKLLISKLKAHQMCFRDYKYRLAKSTLVLIPLLGVHEILFSFITDDQVEGFAKLIRLFI
QLTLSSFHGFLVALQYGFANGEVKAELRKYWVRFLLARHSGCRACVLGKDFRFLGKCPKK
LSEGDGAEKLRKLQPSLNSGRLLHLAMRGLGELGAQPQQDHARWPRGSSLSECSEGDVTM
ANTMEEILEESEI

Sequence length

553

Interactions

View interactions

	KEGG		Reactome
	Neuroactive ligand-receptor interaction		G alpha (s) signalling events Glucagon-type ligand receptors ADORA2B mediated anti-inflammatory cytokines production

GLP2R (glucagon like peptide 2 receptor)