Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9334
|
Gene name
Gene Name - the full gene name approved by the HGNC.
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Beta-1,4-galactosyltransferase 5 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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B4GALT5 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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B4Gal-T5, BETA4-GALT-IV, beta4Gal-T5, beta4GalT-V, gt-V |
Chromosome
Chromosome number
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20 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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20q13.13 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to si |
UniProt ID |
O43286
|
Protein name |
Beta-1,4-galactosyltransferase 5 (Beta-1,4-GalTase 5) (Beta4Gal-T5) (b4Gal-T5) (EC 2.4.1.-) (Beta-1,4-GalT II) (Glucosylceramide beta-1,4-galactosyltransferase) (EC 2.4.1.274) (Lactosylceramide synthase) (LacCer synthase) (UDP-Gal:beta-GlcNAc beta-1,4-gal |
Protein function |
Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:24498430). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphin |
Family and domains |
Pfam
Accession |
ID |
Position in sequence |
Description |
Type |
PF13733
|
Glyco_transf_7N |
114 → 249 |
N-terminal region of glycosyl transferase group 7 |
Domain |
PF02709
|
Glyco_transf_7C |
253 → 331 |
N-terminal domain of galactosyltransferase |
Family |
|
Tissue specificity |
TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:9435216}. |
Sequence |
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Sequence length |
388 |
Interactions |
View interactions
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