Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9326
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger HIT-type containing 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNHIT3
Synonyms (NCBI Gene) Gene synonyms aliases	Hit1, PEHO, TRIP3
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q12

Show/Hide all(160)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024305	hsa-miR-215-5p	Microarray	19074876
MIRT026564	hsa-miR-192-5p	Microarray	19074876
MIRT043888	hsa-miR-378a-3p	CLASH	23622248
MIRT449216	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT449214	hsa-miR-4795-5p	PAR-CLIP	22100165
MIRT449213	hsa-miR-144-5p	PAR-CLIP	22100165
MIRT449212	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT449211	hsa-miR-573	PAR-CLIP	22100165
MIRT449216	hsa-miR-100-3p	PAR-CLIP	22100165
MIRT449214	hsa-miR-4795-5p	PAR-CLIP	22100165
MIRT449213	hsa-miR-144-5p	PAR-CLIP	22100165
MIRT449212	hsa-miR-3616-5p	PAR-CLIP	22100165
MIRT449211	hsa-miR-573	PAR-CLIP	22100165
MIRT1542923	hsa-miR-101	CLIP-seq
MIRT1542924	hsa-miR-1272	CLIP-seq
MIRT1542925	hsa-miR-1322	CLIP-seq
MIRT1542926	hsa-miR-141	CLIP-seq
MIRT1542927	hsa-miR-144	CLIP-seq
MIRT1542928	hsa-miR-200a	CLIP-seq
MIRT1542929	hsa-miR-2052	CLIP-seq
MIRT1542930	hsa-miR-2964a-5p	CLIP-seq
MIRT1542931	hsa-miR-4477a	CLIP-seq
MIRT1542932	hsa-miR-4796-5p	CLIP-seq
MIRT1542933	hsa-miR-548a-5p	CLIP-seq
MIRT1542934	hsa-miR-548ab	CLIP-seq
MIRT1542935	hsa-miR-548ac	CLIP-seq
MIRT1542936	hsa-miR-548ae	CLIP-seq
MIRT1542937	hsa-miR-548aj	CLIP-seq
MIRT1542938	hsa-miR-548ak	CLIP-seq
MIRT1542939	hsa-miR-548am	CLIP-seq
MIRT1542940	hsa-miR-548b-5p	CLIP-seq
MIRT1542941	hsa-miR-548c-5p	CLIP-seq
MIRT1542942	hsa-miR-548d-3p	CLIP-seq
MIRT1542943	hsa-miR-548d-5p	CLIP-seq
MIRT1542944	hsa-miR-548h	CLIP-seq
MIRT1542945	hsa-miR-548i	CLIP-seq
MIRT1542946	hsa-miR-548j	CLIP-seq
MIRT1542947	hsa-miR-548n	CLIP-seq
MIRT1542948	hsa-miR-548w	CLIP-seq
MIRT1542949	hsa-miR-548x	CLIP-seq
MIRT1542950	hsa-miR-548y	CLIP-seq
MIRT1542951	hsa-miR-548z	CLIP-seq
MIRT1542952	hsa-miR-559	CLIP-seq
MIRT1542953	hsa-miR-936	CLIP-seq
MIRT2163785	hsa-miR-136	CLIP-seq
MIRT2163786	hsa-miR-192	CLIP-seq
MIRT2163787	hsa-miR-215	CLIP-seq
MIRT2163788	hsa-miR-3064-3p	CLIP-seq
MIRT2163789	hsa-miR-346	CLIP-seq
MIRT2163790	hsa-miR-3691-3p	CLIP-seq
MIRT2163791	hsa-miR-4477b	CLIP-seq
MIRT2163792	hsa-miR-4715-3p	CLIP-seq
MIRT2163793	hsa-miR-4764-3p	CLIP-seq
MIRT2163794	hsa-miR-4768-5p	CLIP-seq
MIRT2163795	hsa-miR-494	CLIP-seq
MIRT1542924	hsa-miR-1272	CLIP-seq
MIRT1542925	hsa-miR-1322	CLIP-seq
MIRT2163785	hsa-miR-136	CLIP-seq
MIRT1542926	hsa-miR-141	CLIP-seq
MIRT2382979	hsa-miR-15a	CLIP-seq
MIRT2382980	hsa-miR-15b	CLIP-seq
MIRT2382981	hsa-miR-16	CLIP-seq
MIRT2382982	hsa-miR-195	CLIP-seq
MIRT1542928	hsa-miR-200a	CLIP-seq
MIRT2382983	hsa-miR-2355-5p	CLIP-seq
MIRT1542930	hsa-miR-2964a-5p	CLIP-seq
MIRT2163788	hsa-miR-3064-3p	CLIP-seq
MIRT2382984	hsa-miR-3152-5p	CLIP-seq
MIRT2382985	hsa-miR-324-5p	CLIP-seq
MIRT2163789	hsa-miR-346	CLIP-seq
MIRT2382986	hsa-miR-3647-5p	CLIP-seq
MIRT2382987	hsa-miR-3670	CLIP-seq
MIRT2382988	hsa-miR-3690	CLIP-seq
MIRT2163790	hsa-miR-3691-3p	CLIP-seq
MIRT2382989	hsa-miR-424	CLIP-seq
MIRT2382990	hsa-miR-4254	CLIP-seq
MIRT2382991	hsa-miR-4261	CLIP-seq
MIRT2382992	hsa-miR-4323	CLIP-seq
MIRT1542931	hsa-miR-4477a	CLIP-seq
MIRT2163791	hsa-miR-4477b	CLIP-seq
MIRT2163792	hsa-miR-4715-3p	CLIP-seq
MIRT2163793	hsa-miR-4764-3p	CLIP-seq
MIRT2382993	hsa-miR-4774-3p	CLIP-seq
MIRT2382994	hsa-miR-4793-5p	CLIP-seq
MIRT1542932	hsa-miR-4796-5p	CLIP-seq
MIRT2163795	hsa-miR-494	CLIP-seq
MIRT2382995	hsa-miR-497	CLIP-seq
MIRT2382996	hsa-miR-875-3p	CLIP-seq
MIRT1542926	hsa-miR-141	CLIP-seq
MIRT1542928	hsa-miR-200a	CLIP-seq
MIRT2163793	hsa-miR-4764-3p	CLIP-seq
MIRT1542924	hsa-miR-1272	CLIP-seq
MIRT1542925	hsa-miR-1322	CLIP-seq
MIRT2163786	hsa-miR-192	CLIP-seq
MIRT2163787	hsa-miR-215	CLIP-seq
MIRT2382983	hsa-miR-2355-5p	CLIP-seq
MIRT1542930	hsa-miR-2964a-5p	CLIP-seq
MIRT2382984	hsa-miR-3152-5p	CLIP-seq
MIRT2673489	hsa-miR-3192	CLIP-seq
MIRT2382985	hsa-miR-324-5p	CLIP-seq
MIRT2382986	hsa-miR-3647-5p	CLIP-seq
MIRT2673490	hsa-miR-3663-5p	CLIP-seq
MIRT2382987	hsa-miR-3670	CLIP-seq
MIRT2382988	hsa-miR-3690	CLIP-seq
MIRT2382990	hsa-miR-4254	CLIP-seq
MIRT2382991	hsa-miR-4261	CLIP-seq
MIRT2673491	hsa-miR-4314	CLIP-seq
MIRT2382992	hsa-miR-4323	CLIP-seq
MIRT2673492	hsa-miR-4419a	CLIP-seq
MIRT2673493	hsa-miR-4433	CLIP-seq
MIRT2673494	hsa-miR-4484	CLIP-seq
MIRT2673495	hsa-miR-4510	CLIP-seq
MIRT2673496	hsa-miR-4514	CLIP-seq
MIRT2673497	hsa-miR-4527	CLIP-seq
MIRT2673498	hsa-miR-4646-5p	CLIP-seq
MIRT2673499	hsa-miR-4661-5p	CLIP-seq
MIRT2673500	hsa-miR-4690-5p	CLIP-seq
MIRT2673501	hsa-miR-4692	CLIP-seq
MIRT2673502	hsa-miR-4736	CLIP-seq
MIRT2163793	hsa-miR-4764-3p	CLIP-seq
MIRT2382993	hsa-miR-4774-3p	CLIP-seq
MIRT2382994	hsa-miR-4793-5p	CLIP-seq
MIRT1542932	hsa-miR-4796-5p	CLIP-seq
MIRT2163795	hsa-miR-494	CLIP-seq
MIRT2673503	hsa-miR-548an	CLIP-seq
MIRT1542947	hsa-miR-548n	CLIP-seq
MIRT2673504	hsa-miR-657	CLIP-seq
MIRT2673505	hsa-miR-665	CLIP-seq
MIRT2382996	hsa-miR-875-3p	CLIP-seq
MIRT2673506	hsa-miR-940	CLIP-seq
MIRT2163786	hsa-miR-192	CLIP-seq
MIRT2163787	hsa-miR-215	CLIP-seq
MIRT2382983	hsa-miR-2355-5p	CLIP-seq
MIRT2382984	hsa-miR-3152-5p	CLIP-seq
MIRT2673489	hsa-miR-3192	CLIP-seq
MIRT2382985	hsa-miR-324-5p	CLIP-seq
MIRT2673490	hsa-miR-3663-5p	CLIP-seq
MIRT2382987	hsa-miR-3670	CLIP-seq
MIRT2382988	hsa-miR-3690	CLIP-seq
MIRT2382990	hsa-miR-4254	CLIP-seq
MIRT2382991	hsa-miR-4261	CLIP-seq
MIRT2673491	hsa-miR-4314	CLIP-seq
MIRT2382992	hsa-miR-4323	CLIP-seq
MIRT2673492	hsa-miR-4419a	CLIP-seq
MIRT2673494	hsa-miR-4484	CLIP-seq
MIRT2673495	hsa-miR-4510	CLIP-seq
MIRT2673496	hsa-miR-4514	CLIP-seq
MIRT2673497	hsa-miR-4527	CLIP-seq
MIRT2673498	hsa-miR-4646-5p	CLIP-seq
MIRT2673499	hsa-miR-4661-5p	CLIP-seq
MIRT2673500	hsa-miR-4690-5p	CLIP-seq
MIRT2673501	hsa-miR-4692	CLIP-seq
MIRT2673502	hsa-miR-4736	CLIP-seq
MIRT2382993	hsa-miR-4774-3p	CLIP-seq
MIRT2382994	hsa-miR-4793-5p	CLIP-seq
MIRT2163795	hsa-miR-494	CLIP-seq
MIRT2673503	hsa-miR-548an	CLIP-seq
MIRT2673504	hsa-miR-657	CLIP-seq
MIRT2382996	hsa-miR-875-3p	CLIP-seq
MIRT2673506	hsa-miR-940	CLIP-seq

Show/Hide all(13)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000463	Process	Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA
GO:0000492	Process	Box C/D snoRNP assembly	IBA
GO:0005515	Function	Protein binding	IPI	25170085, 28335020, 28514442, 32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	28335020
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IDA	28335020
GO:0005737	Component	Cytoplasm	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	TAS	7776974
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0046966	Function	Nuclear thyroid hormone receptor binding	TAS	7776974
GO:0070761	Component	Pre-snoRNP complex	IBA

MIM	HGNC	e!Ensembl
604500	12309	ENSG00000273611

Protein

UniProt ID

Q15649

Protein name

Zinc finger HIT domain-containing protein 3 (HNF-4a coactivator) (Thyroid hormone receptor interactor 3) (Thyroid receptor-interacting protein 3) (TR-interacting protein 3) (TRIP-3)

PDB

2YQQ , 5L85

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04438	zf-HIT	7 → 36	HIT zinc finger	Domain

Sequence

MASLKCSTVVCVICLEKPKYRCPACRVPYCSVVCFRKHKEQCNPETRPVEKKIRSALPTK
TVKPVENKDDDDSIADFLNSDEEEDRVSLQNLKNLGESATLRSLLLNPHLRQLMVNLDQG
EDKAKLMRAYMQEPLFVEFADCCLGIVEPSQNEES

Sequence length

155

Interactions

View interactions

Show/Hide Causal Diseases (1)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
PEHO Syndrome	peho syndrome	rs148890852	N/A

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Metabolic Syndrome	Metabolic syndrome	N/A	N/A	GWAS
Multiple Sclerosis	Multiple sclerosis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Amyotrophic Lateral Sclerosis	Associate	28639078
Developmental Disabilities	Associate	35843310
Diabetes Mellitus Type 2	Associate	17656577
Mason Type Diabetes	Associate	17656577
PEHO syndrome	Associate	31048081, 35843310

ZNHIT3 (zinc finger HIT-type containing 3)