NREP (neuronal regeneration related protein)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9315
Gene name Gene Name - the full gene name approved by the HGNC.
Neuronal regeneration related protein
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
NREP
Synonyms (NCBI Gene) Gene synonyms aliases
C5orf13, D4S114, P311, PRO1873, PTZ17, SEZ17
Chromosome Chromosome number
5
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
5q22.1
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(24)
miRTarBase ID miRNA Experiments Reference
MIRT024413 hsa-miR-215-5p Microarray 19074876
MIRT026664 hsa-miR-192-5p Microarray 19074876
MIRT027728 hsa-miR-98-5p Microarray 19088304
MIRT048382 hsa-miR-29b-3p CLASH 23622248
MIRT561843 hsa-miR-7-5p PAR-CLIP 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(6)
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 22365962
GO:0005634 Component Nucleus IBA 21873635
GO:0005737 Component Cytoplasm IBA 21873635
GO:0017015 Process Regulation of transforming growth factor beta receptor signaling pathway IBA 21873635
GO:0031103 Process Axon regeneration IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
607332 16834 ENSG00000134986
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q16612
Protein name Neuronal regeneration-related protein (Neuronal protein 3.1) (Protein p311)
Protein function May have roles in neural function. Ectopic expression augments motility of gliomas. Also promotes axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast int
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF11092 Alveol-reg_P311 2 → 68 Neuronal protein 3.1 (p311) Family
Tissue specificity TISSUE SPECIFICITY: Expressed in lung (at protein level). {ECO:0000269|PubMed:16484684}.
Sequence
Sequence length 68
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Breast carcinoma Breast Carcinoma rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451
View all (71 more)		 29059683
Show/Hide Unknown Diseases (6)
Unknown
Disease term Disease name Evidence References Source
Coronary artery disease Coronary artery disease GWAS
Breast Cancer Breast Cancer Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients GWAS, CBGDA
Metabolic Syndrome Metabolic Syndrome GWAS
Otitis media Otitis media GWAS
Show/Hide Text Mining Associations (13)
Associations from Text Mining
Disease Name Relationship Type References
Depressive Disorder Associate 34972135
Fatty Liver Associate 37354909
Fibrosis Associate 19946746
Glioma Associate 16229809
Glomerulonephritis IGA Associate 19946746
Leukemia Myeloid Acute Associate 37798266
Metabolic Syndrome Associate 37354909
Migraine Disorders Associate 34972135
Neuroblastoma Associate 11501497
Non alcoholic Fatty Liver Disease Associate 37354909