Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	93099
Gene name	Dermokine
Gene symbol	DMKN
Synonyms (NCBI Gene)	UNQ729ZD52F10
Chromosome	19
Chromosome location	19q13.12
Summary	This gene is upregulated in inflammatory diseases, and it was first observed as expressed in the differentiated layers of skin. The most interesting aspect of this gene is the differential use of promoters and terminators to generate isoforms with unique

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miRTarBase ID	miRNA	Experiments	Reference
MIRT027972	hsa-miR-93-5p	Sequencing	20371350
MIRT045834	hsa-miR-138-5p	CLASH	23622248
MIRT514913	hsa-miR-1273g-3p	PAR-CLIP	21572407
MIRT514911	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT514912	hsa-miR-6742-3p	PAR-CLIP	21572407
MIRT514910	hsa-miR-1292-3p	PAR-CLIP	21572407
MIRT514909	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT514908	hsa-miR-191-3p	PAR-CLIP	21572407
MIRT514906	hsa-miR-6776-5p	PAR-CLIP	21572407
MIRT514907	hsa-miR-4252	PAR-CLIP	21572407
MIRT514905	hsa-miR-661	PAR-CLIP	21572407
MIRT541730	hsa-miR-4683	PAR-CLIP	21572407
MIRT541729	hsa-miR-542-3p	PAR-CLIP	21572407
MIRT514904	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT514903	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT514902	hsa-miR-1262	PAR-CLIP	21572407
MIRT514901	hsa-miR-4701-3p	PAR-CLIP	21572407
MIRT514900	hsa-miR-6736-5p	PAR-CLIP	21572407
MIRT514913	hsa-miR-1273g-3p	PAR-CLIP	23446348
MIRT514911	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT514912	hsa-miR-6742-3p	PAR-CLIP	23446348
MIRT514910	hsa-miR-1292-3p	PAR-CLIP	23446348
MIRT514909	hsa-miR-766-3p	PAR-CLIP	23446348
MIRT514908	hsa-miR-191-3p	PAR-CLIP	23446348
MIRT514906	hsa-miR-6776-5p	PAR-CLIP	23446348
MIRT514907	hsa-miR-4252	PAR-CLIP	23446348
MIRT514905	hsa-miR-661	PAR-CLIP	23446348
MIRT514904	hsa-miR-6512-3p	PAR-CLIP	23446348
MIRT514903	hsa-miR-6720-5p	PAR-CLIP	23446348
MIRT514902	hsa-miR-1262	PAR-CLIP	23446348
MIRT514901	hsa-miR-4701-3p	PAR-CLIP	23446348
MIRT514900	hsa-miR-6736-5p	PAR-CLIP	23446348
MIRT514902	hsa-miR-1262	PAR-CLIP	27292025
MIRT514913	hsa-miR-1273g-3p	PAR-CLIP	27292025
MIRT514910	hsa-miR-1292-3p	PAR-CLIP	27292025
MIRT514908	hsa-miR-191-3p	PAR-CLIP	27292025
MIRT514907	hsa-miR-4252	PAR-CLIP	27292025
MIRT514901	hsa-miR-4701-3p	PAR-CLIP	27292025
MIRT541729	hsa-miR-542-3p	PAR-CLIP	27292025
MIRT514904	hsa-miR-6512-3p	PAR-CLIP	27292025
MIRT514905	hsa-miR-661	PAR-CLIP	27292025
MIRT514903	hsa-miR-6720-5p	PAR-CLIP	27292025
MIRT514900	hsa-miR-6736-5p	PAR-CLIP	27292025
MIRT514912	hsa-miR-6742-3p	PAR-CLIP	27292025
MIRT514906	hsa-miR-6776-5p	PAR-CLIP	27292025
MIRT514911	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT514909	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT514913	hsa-miR-1273g-3p	PAR-CLIP	21572407
MIRT514911	hsa-miR-6849-3p	PAR-CLIP	21572407
MIRT514912	hsa-miR-6742-3p	PAR-CLIP	21572407
MIRT514910	hsa-miR-1292-3p	PAR-CLIP	21572407
MIRT514909	hsa-miR-766-3p	PAR-CLIP	21572407
MIRT514908	hsa-miR-191-3p	PAR-CLIP	21572407
MIRT514906	hsa-miR-6776-5p	PAR-CLIP	21572407
MIRT514907	hsa-miR-4252	PAR-CLIP	21572407
MIRT514905	hsa-miR-661	PAR-CLIP	21572407
MIRT541730	hsa-miR-4683	PAR-CLIP	21572407
MIRT541729	hsa-miR-542-3p	PAR-CLIP	21572407
MIRT514904	hsa-miR-6512-3p	PAR-CLIP	21572407
MIRT514903	hsa-miR-6720-5p	PAR-CLIP	21572407
MIRT514902	hsa-miR-1262	PAR-CLIP	21572407
MIRT514901	hsa-miR-4701-3p	PAR-CLIP	21572407
MIRT514900	hsa-miR-6736-5p	PAR-CLIP	21572407
MIRT514913	hsa-miR-1273g-3p	PAR-CLIP	23446348
MIRT514911	hsa-miR-6849-3p	PAR-CLIP	23446348
MIRT514912	hsa-miR-6742-3p	PAR-CLIP	23446348
MIRT514910	hsa-miR-1292-3p	PAR-CLIP	23446348
MIRT514909	hsa-miR-766-3p	PAR-CLIP	23446348
MIRT514908	hsa-miR-191-3p	PAR-CLIP	23446348
MIRT514906	hsa-miR-6776-5p	PAR-CLIP	23446348
MIRT514907	hsa-miR-4252	PAR-CLIP	23446348
MIRT514905	hsa-miR-661	PAR-CLIP	23446348
MIRT514904	hsa-miR-6512-3p	PAR-CLIP	23446348
MIRT514903	hsa-miR-6720-5p	PAR-CLIP	23446348
MIRT514902	hsa-miR-1262	PAR-CLIP	23446348
MIRT514901	hsa-miR-4701-3p	PAR-CLIP	23446348
MIRT514900	hsa-miR-6736-5p	PAR-CLIP	23446348
MIRT939119	hsa-miR-128	CLIP-seq
MIRT939120	hsa-miR-1321	CLIP-seq
MIRT939121	hsa-miR-138	CLIP-seq
MIRT939122	hsa-miR-140-3p	CLIP-seq
MIRT939123	hsa-miR-148a	CLIP-seq
MIRT939124	hsa-miR-148b	CLIP-seq
MIRT939125	hsa-miR-152	CLIP-seq
MIRT939126	hsa-miR-29a	CLIP-seq
MIRT939127	hsa-miR-29b	CLIP-seq
MIRT939128	hsa-miR-29c	CLIP-seq
MIRT939129	hsa-miR-3164	CLIP-seq
MIRT939130	hsa-miR-4456	CLIP-seq
MIRT939131	hsa-miR-4701-5p	CLIP-seq
MIRT939132	hsa-miR-4739	CLIP-seq
MIRT939133	hsa-miR-4747-5p	CLIP-seq
MIRT939134	hsa-miR-4756-5p	CLIP-seq
MIRT939135	hsa-miR-485-5p	CLIP-seq
MIRT939136	hsa-miR-588	CLIP-seq
MIRT939137	hsa-miR-617	CLIP-seq
MIRT939119	hsa-miR-128	CLIP-seq
MIRT939122	hsa-miR-140-3p	CLIP-seq
MIRT939123	hsa-miR-148a	CLIP-seq
MIRT939124	hsa-miR-148b	CLIP-seq
MIRT939125	hsa-miR-152	CLIP-seq
MIRT939138	hsa-miR-185	CLIP-seq
MIRT939139	hsa-miR-2355-5p	CLIP-seq
MIRT939126	hsa-miR-29a	CLIP-seq
MIRT939127	hsa-miR-29b	CLIP-seq
MIRT939128	hsa-miR-29c	CLIP-seq
MIRT939140	hsa-miR-3135	CLIP-seq
MIRT939141	hsa-miR-320e	CLIP-seq
MIRT939142	hsa-miR-4306	CLIP-seq
MIRT939143	hsa-miR-4428	CLIP-seq
MIRT939144	hsa-miR-4644	CLIP-seq
MIRT939133	hsa-miR-4747-5p	CLIP-seq
MIRT939129	hsa-miR-3164	CLIP-seq
MIRT1977835	hsa-miR-3692	CLIP-seq
MIRT1977836	hsa-miR-371b-5p	CLIP-seq
MIRT1977837	hsa-miR-3919	CLIP-seq
MIRT1977838	hsa-miR-548n	CLIP-seq
MIRT939137	hsa-miR-617	CLIP-seq
MIRT1977839	hsa-miR-888	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	22735594, 32296183
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IBA
GO:1903575	Process	Cornified envelope assembly	IBA
GO:1903575	Process	Cornified envelope assembly	IEA

MIM	HGNC	e!Ensembl
617211	25063	ENSG00000161249

Q6E0U4

Protein name

Dermokine (Epidermis-specific secreted protein SK30/SK89)

Protein function

May act as a soluble regulator of keratinocyte differentiation.

PDB

4F20

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in epidermis; in the spinous and granular layers and in placenta. Also found in the epithelia of the small intestine, macrophages of the lung and endothelial cells of the lung. Isoform 15 is expressed in epidermis and placent

Sequence

MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAG
GAAGSKVSEALGQGTREAVGTGVRQVPGFGVADALGNRVGEAAHALGNTGHEIGRQAEDV
IRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS
AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGG
SSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDS
GSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETSPGMFNFDTF
WKNFKSKLGFINWDAINKNQVPPPSTRALLYFSRLWEDFKQNTPFLNWKAIIEGADASSL
QKRAGRDDQNYNYNQHAYPTAYGGKYSVKTPAKGGVSPSSSASRVQPGLLQWVKFW

Sequence length

476

Interactions

View interactions

DMKN (dermokine)