S1PR2 (sphingosine-1-phosphate receptor 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9294 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Sphingosine-1-phosphate receptor 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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S1PR2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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AGR16, DFNB68, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2 |
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Chromosome
Chromosome number
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19 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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19p13.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defect |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | O95136 | ||||||||||
| Protein name | Sphingosine 1-phosphate receptor 2 (S1P receptor 2) (S1P2) (Endothelial differentiation G-protein coupled receptor 5) (Sphingosine 1-phosphate receptor Edg-5) (S1P receptor Edg-5) | ||||||||||
| Protein function | Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P) (PubMed:10617617, PubMed:25274307). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues (PubMed:10617617). When express | ||||||||||
| PDB | 7T6B | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 353 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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