STK17B (serine/threonine kinase 17b)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 9262 |
| Gene name | Serine/threonine kinase 17b |
| Gene symbol | STK17B |
| Synonyms (NCBI Gene) |
DRAK2
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| Chromosome | 2 |
| Chromosome location | 2q32.3 |
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miRNA
miRNA information provided by mirtarbase database.
663
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
30
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O94768 | ||||||||||
| Protein name | Serine/threonine-protein kinase 17B (EC 2.7.11.1) (DAP kinase-related apoptosis-inducing protein kinase 2) | ||||||||||
| Protein function | Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis. | ||||||||||
| PDB | 3LM0 , 3LM5 , 6QF4 , 6Y6F , 6Y6H , 6ZJF , 7AKG , 7Q7C , 7Q7D , 7Q7E | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. {ECO:0000269|PubMed:9786912}. | ||||||||||
| Sequence |
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| Sequence length | 372 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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