Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	92483
Gene name Gene Name - the full gene name approved by the HGNC.	Lactate dehydrogenase A like 6B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LDHAL6B
Synonyms (NCBI Gene) Gene synonyms aliases	LDH6B, LDHAL6, LDHL
Chromosome Chromosome number	15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	15q22.2

Show/Hide all(20)

miRTarBase ID	miRNA	Experiments
MIRT1106391	hsa-miR-302a	CLIP-seq
MIRT1106392	hsa-miR-302b	CLIP-seq
MIRT1106393	hsa-miR-302c	CLIP-seq
MIRT1106394	hsa-miR-302d	CLIP-seq
MIRT1106395	hsa-miR-302e	CLIP-seq
MIRT1106396	hsa-miR-31	CLIP-seq
MIRT1106397	hsa-miR-372	CLIP-seq
MIRT1106398	hsa-miR-373	CLIP-seq
MIRT1106399	hsa-miR-410	CLIP-seq
MIRT1106400	hsa-miR-512-3p	CLIP-seq
MIRT1106401	hsa-miR-520a-3p	CLIP-seq
MIRT1106402	hsa-miR-520b	CLIP-seq
MIRT1106403	hsa-miR-520c-3p	CLIP-seq
MIRT1106404	hsa-miR-520d-3p	CLIP-seq
MIRT1106405	hsa-miR-520e	CLIP-seq
MIRT1921259	hsa-miR-1276	CLIP-seq
MIRT1921260	hsa-miR-3135b	CLIP-seq
MIRT1921261	hsa-miR-4487	CLIP-seq
MIRT1921262	hsa-miR-4759	CLIP-seq
MIRT1921263	hsa-miR-765	CLIP-seq

Show/Hide all(7)

GO ID	Ontology	Definition	Evidence	Reference
GO:0004459	Function	L-lactate dehydrogenase activity	IBA	21873635
GO:0004459	Function	L-lactate dehydrogenase activity	TAS
GO:0005515	Function	Protein binding	IPI	12107167, 32814053
GO:0005634	Component	Nucleus	HDA	21630459
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0005975	Process	Carbohydrate metabolic process	IEA
GO:0006090	Process	Pyruvate metabolic process	TAS

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Protein

UniProt ID

Q9BYZ2

Protein name

L-lactate dehydrogenase A-like 6B (EC 1.1.1.27)

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00056	Ldh_1_N	70 → 209	lactate/malate dehydrogenase, NAD binding domain	Family
PF02866	Ldh_1_C	212 → 380	lactate/malate dehydrogenase, alpha/beta C-terminal domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Testis specific.

Sequence

MSWTVPVVRASQRVSSVGANFLCLGMALCPRQATRIPLNGTWLFTPVSKMATVKSELIER
FTSEKPVHHSKVSIIGTGSVGMACAISILLKGLSDELALVDLDEDKLKGETMDLQHGSPF
TKMPNIVCSKDYFVTANSNLVIITAGARQEKGETRLNLVQRNVAIFKLMISSIVQYSPHC
KLIIVSNPVDILTYVAWKLSAFPKNRIIGSGCNLDTARFRFLIGQKLGIHSESCHGWILG
EHGDSSVPVWSGVNIAGVPLKDLNSDIGTDKDPEQWKNVHKEVTATAYEIIKMKGYTSWA
IGLSVADLTESILKNLRRIHPVSTIIKGLYGIDEEVFLSIPCILGENGITNLIKIKLTPE
EEAHLKKSAKTLWEIQNKLKL

Sequence length

381

Interactions

View interactions

	KEGG		Reactome
	Glycolysis / Gluconeogenesis Cysteine and methionine metabolism Pyruvate metabolism Propanoate metabolism Metabolic pathways HIF-1 signaling pathway Glucagon signaling pathway Central carbon metabolism in cancer		Pyruvate metabolism

Show/Hide Causal Diseases (3)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)	20562527
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	20562527
Marfan syndrome	Mammary Carcinoma, Human	rs137854456, rs137854457, rs267606796, rs137854458, rs137854459, rs137854460, rs137854470, rs137854471, rs267606797, rs137854461, rs137854462, rs137854463, rs869025419, rs137854464, rs137854465 View all (942 more)	20562527

LDHAL6B (lactate dehydrogenase A like 6B)