SPSB4 (splA/ryanodine receptor domain and SOCS box containing 4)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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92369 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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SplA/ryanodine receptor domain and SOCS box containing 4 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SPSB4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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SSB-4, SSB4 |
Chromosome
Chromosome number
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3 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3q23 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q96A44 | |||||||||||||||
Protein name | SPRY domain-containing SOCS box protein 4 (SSB-4) | |||||||||||||||
Protein function | Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820, PubMed:21199 | |||||||||||||||
PDB | 2V24 , 6DN7 , 6DN8 | |||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 273 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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