Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9208
Gene name Gene Name - the full gene name approved by the HGNC.	LRR binding FLII interacting protein 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LRRFIP1
Synonyms (NCBI Gene) Gene synonyms aliases	FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q37.3

Show/Hide all(328)

miRTarBase ID	miRNA	Experiments	Reference
MIRT001220	hsa-miR-21-5p	semi-qRT-PCR, Luciferase reporter assay, Western blot	19559015
MIRT001220	hsa-miR-21-5p	Luciferase reporter assay	19559015
MIRT001220	hsa-miR-21-5p	Luciferase reporter assay	19559015
MIRT001220	hsa-miR-21-5p	Luciferase reporter assay	19559015
MIRT005182	hsa-miR-30a-5p	pSILAC	18668040
MIRT024762	hsa-miR-215-5p	Microarray	19074876
MIRT025366	hsa-miR-34a-5p	Proteomics	21566225
MIRT025366	hsa-miR-34a-5p	Proteomics	21566225
MIRT026309	hsa-miR-192-5p	Microarray	19074876
MIRT005182	hsa-miR-30a-5p	Proteomics;Other	18668040
MIRT045426	hsa-miR-149-5p	CLASH	23622248
MIRT045105	hsa-miR-186-5p	CLASH	23622248
MIRT037289	hsa-miR-877-5p	CLASH	23622248
MIRT037048	hsa-miR-877-3p	CLASH	23622248
MIRT001220	hsa-miR-21-5p	Immunohistochemistry, Western blot	24690174
MIRT648109	hsa-miR-4267	HITS-CLIP	23824327
MIRT037048	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT648108	hsa-miR-1266-3p	HITS-CLIP	23824327
MIRT648107	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT648106	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT648105	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT648104	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT648103	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT648102	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT648101	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT648100	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT648098	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT648099	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT648097	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT648096	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT648095	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT440307	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT440307	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT648109	hsa-miR-4267	HITS-CLIP	23824327
MIRT037048	hsa-miR-877-3p	HITS-CLIP	23824327
MIRT648108	hsa-miR-1266-3p	HITS-CLIP	23824327
MIRT648107	hsa-miR-6734-3p	HITS-CLIP	23824327
MIRT648106	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT648105	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT648104	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT648103	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT648102	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT648101	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT648100	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT648098	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT648099	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT648097	hsa-miR-6868-3p	HITS-CLIP	23824327
MIRT648096	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT648095	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT1120793	hsa-miR-3674	CLIP-seq
MIRT1120794	hsa-miR-3935	CLIP-seq
MIRT1120795	hsa-miR-4659a-5p	CLIP-seq
MIRT1120796	hsa-miR-4659b-5p	CLIP-seq
MIRT1120797	hsa-miR-4724-5p	CLIP-seq
MIRT1120798	hsa-miR-4727-5p	CLIP-seq
MIRT1120799	hsa-miR-4769-3p	CLIP-seq
MIRT1120800	hsa-miR-488	CLIP-seq
MIRT1120801	hsa-miR-122	CLIP-seq
MIRT1120802	hsa-miR-124	CLIP-seq
MIRT1120803	hsa-miR-133a	CLIP-seq
MIRT1120804	hsa-miR-133b	CLIP-seq
MIRT1120805	hsa-miR-337-3p	CLIP-seq
MIRT1120806	hsa-miR-3652	CLIP-seq
MIRT1120807	hsa-miR-3714	CLIP-seq
MIRT1120808	hsa-miR-3910	CLIP-seq
MIRT1120809	hsa-miR-4430	CLIP-seq
MIRT1120810	hsa-miR-4438	CLIP-seq
MIRT1120811	hsa-miR-4505	CLIP-seq
MIRT1120812	hsa-miR-4797-5p	CLIP-seq
MIRT1120813	hsa-miR-506	CLIP-seq
MIRT1120814	hsa-miR-5095	CLIP-seq
MIRT1120815	hsa-miR-516b	CLIP-seq
MIRT1120816	hsa-let-7a	CLIP-seq
MIRT1120817	hsa-let-7b	CLIP-seq
MIRT1120818	hsa-let-7c	CLIP-seq
MIRT1120819	hsa-let-7d	CLIP-seq
MIRT1120820	hsa-let-7e	CLIP-seq
MIRT1120821	hsa-let-7f	CLIP-seq
MIRT1120822	hsa-let-7g	CLIP-seq
MIRT1120823	hsa-let-7i	CLIP-seq
MIRT1120824	hsa-miR-103b	CLIP-seq
MIRT1120825	hsa-miR-1184	CLIP-seq
MIRT1120826	hsa-miR-129-5p	CLIP-seq
MIRT1120827	hsa-miR-1303	CLIP-seq
MIRT1120828	hsa-miR-132	CLIP-seq
MIRT1120829	hsa-miR-1324	CLIP-seq
MIRT1120830	hsa-miR-154	CLIP-seq
MIRT1120831	hsa-miR-181a	CLIP-seq
MIRT1120832	hsa-miR-181b	CLIP-seq
MIRT1120833	hsa-miR-181c	CLIP-seq
MIRT1120834	hsa-miR-181d	CLIP-seq
MIRT1120835	hsa-miR-192	CLIP-seq
MIRT1120836	hsa-miR-194	CLIP-seq
MIRT1120837	hsa-miR-19a	CLIP-seq
MIRT1120838	hsa-miR-19b	CLIP-seq
MIRT1120839	hsa-miR-202	CLIP-seq
MIRT1120840	hsa-miR-212	CLIP-seq
MIRT1120841	hsa-miR-215	CLIP-seq
MIRT1120842	hsa-miR-3065-5p	CLIP-seq
MIRT1120843	hsa-miR-3074-3p	CLIP-seq
MIRT1120844	hsa-miR-3121-5p	CLIP-seq
MIRT1120845	hsa-miR-3149	CLIP-seq
MIRT1120846	hsa-miR-3160-5p	CLIP-seq
MIRT1120847	hsa-miR-3163	CLIP-seq
MIRT1120848	hsa-miR-33a	CLIP-seq
MIRT1120849	hsa-miR-33b	CLIP-seq
MIRT1120850	hsa-miR-3545-3p	CLIP-seq
MIRT1120851	hsa-miR-362-5p	CLIP-seq
MIRT1120852	hsa-miR-3662	CLIP-seq
MIRT1120853	hsa-miR-374a	CLIP-seq
MIRT1120854	hsa-miR-374b	CLIP-seq
MIRT1120855	hsa-miR-3942-3p	CLIP-seq
MIRT1120856	hsa-miR-4262	CLIP-seq
MIRT1120857	hsa-miR-4418	CLIP-seq
MIRT1120858	hsa-miR-4458	CLIP-seq
MIRT1120859	hsa-miR-4484	CLIP-seq
MIRT1120860	hsa-miR-4500	CLIP-seq
MIRT1120861	hsa-miR-450b-5p	CLIP-seq
MIRT1120862	hsa-miR-4517	CLIP-seq
MIRT1120863	hsa-miR-4680-5p	CLIP-seq
MIRT1120864	hsa-miR-4687-3p	CLIP-seq
MIRT1120865	hsa-miR-4699-3p	CLIP-seq
MIRT1120866	hsa-miR-4749-3p	CLIP-seq
MIRT1120867	hsa-miR-500b	CLIP-seq
MIRT1120868	hsa-miR-501-5p	CLIP-seq
MIRT1120869	hsa-miR-505	CLIP-seq
MIRT1120870	hsa-miR-507	CLIP-seq
MIRT1120871	hsa-miR-509-3-5p	CLIP-seq
MIRT1120872	hsa-miR-509-5p	CLIP-seq
MIRT1120873	hsa-miR-543	CLIP-seq
MIRT1120874	hsa-miR-548ag	CLIP-seq
MIRT1120875	hsa-miR-548ai	CLIP-seq
MIRT1120876	hsa-miR-548an	CLIP-seq
MIRT1120877	hsa-miR-552	CLIP-seq
MIRT1120878	hsa-miR-557	CLIP-seq
MIRT1120879	hsa-miR-590-3p	CLIP-seq
MIRT1120880	hsa-miR-643	CLIP-seq
MIRT1120881	hsa-miR-647	CLIP-seq
MIRT1120882	hsa-miR-758	CLIP-seq
MIRT1120883	hsa-miR-98	CLIP-seq
MIRT1120835	hsa-miR-192	CLIP-seq
MIRT1120836	hsa-miR-194	CLIP-seq
MIRT1120841	hsa-miR-215	CLIP-seq
MIRT2034229	hsa-miR-4289	CLIP-seq
MIRT1120879	hsa-miR-590-3p	CLIP-seq
MIRT1120824	hsa-miR-103b	CLIP-seq
MIRT1120825	hsa-miR-1184	CLIP-seq
MIRT1120801	hsa-miR-122	CLIP-seq
MIRT2264585	hsa-miR-1224-3p	CLIP-seq
MIRT2264586	hsa-miR-1260	CLIP-seq
MIRT2264587	hsa-miR-1260b	CLIP-seq
MIRT2264588	hsa-miR-1262	CLIP-seq
MIRT2264589	hsa-miR-1280	CLIP-seq
MIRT2264590	hsa-miR-1283	CLIP-seq
MIRT1120828	hsa-miR-132	CLIP-seq
MIRT2264591	hsa-miR-1323	CLIP-seq
MIRT1120829	hsa-miR-1324	CLIP-seq
MIRT2264592	hsa-miR-135a	CLIP-seq
MIRT2264593	hsa-miR-135b	CLIP-seq
MIRT2264594	hsa-miR-150	CLIP-seq
MIRT1120831	hsa-miR-181a	CLIP-seq
MIRT1120832	hsa-miR-181b	CLIP-seq
MIRT1120833	hsa-miR-181c	CLIP-seq
MIRT1120834	hsa-miR-181d	CLIP-seq
MIRT2264595	hsa-miR-185	CLIP-seq
MIRT2264596	hsa-miR-1915	CLIP-seq
MIRT1120835	hsa-miR-192	CLIP-seq
MIRT1120836	hsa-miR-194	CLIP-seq
MIRT2264597	hsa-miR-198	CLIP-seq
MIRT1120837	hsa-miR-19a	CLIP-seq
MIRT1120838	hsa-miR-19b	CLIP-seq
MIRT2264598	hsa-miR-200b	CLIP-seq
MIRT2264599	hsa-miR-200c	CLIP-seq
MIRT1120840	hsa-miR-212	CLIP-seq
MIRT1120841	hsa-miR-215	CLIP-seq
MIRT2264600	hsa-miR-216b	CLIP-seq
MIRT2264601	hsa-miR-217	CLIP-seq
MIRT2264602	hsa-miR-2278	CLIP-seq
MIRT2264603	hsa-miR-299-5p	CLIP-seq
MIRT1120842	hsa-miR-3065-5p	CLIP-seq
MIRT2264604	hsa-miR-3120-5p	CLIP-seq
MIRT1120844	hsa-miR-3121-5p	CLIP-seq
MIRT2264605	hsa-miR-3135b	CLIP-seq
MIRT2264606	hsa-miR-3150a-5p	CLIP-seq
MIRT2264607	hsa-miR-3150b-5p	CLIP-seq
MIRT1120846	hsa-miR-3160-5p	CLIP-seq
MIRT1120847	hsa-miR-3163	CLIP-seq
MIRT2264608	hsa-miR-3183	CLIP-seq
MIRT2264609	hsa-miR-34a	CLIP-seq
MIRT2264610	hsa-miR-34c-5p	CLIP-seq
MIRT1120850	hsa-miR-3545-3p	CLIP-seq
MIRT2264611	hsa-miR-3616-5p	CLIP-seq
MIRT2264612	hsa-miR-3646	CLIP-seq
MIRT2264613	hsa-miR-3647-5p	CLIP-seq
MIRT1120806	hsa-miR-3652	CLIP-seq
MIRT1120852	hsa-miR-3662	CLIP-seq
MIRT2264614	hsa-miR-3663-3p	CLIP-seq
MIRT2264615	hsa-miR-3664-5p	CLIP-seq
MIRT2264616	hsa-miR-3671	CLIP-seq
MIRT2264617	hsa-miR-380	CLIP-seq
MIRT1120855	hsa-miR-3942-3p	CLIP-seq
MIRT1120856	hsa-miR-4262	CLIP-seq
MIRT2264618	hsa-miR-4263	CLIP-seq
MIRT2264619	hsa-miR-4269	CLIP-seq
MIRT2264620	hsa-miR-4275	CLIP-seq
MIRT2264621	hsa-miR-4276	CLIP-seq
MIRT2264622	hsa-miR-429	CLIP-seq
MIRT2264623	hsa-miR-4302	CLIP-seq
MIRT2264624	hsa-miR-4306	CLIP-seq
MIRT2264625	hsa-miR-4310	CLIP-seq
MIRT1120857	hsa-miR-4418	CLIP-seq
MIRT2264626	hsa-miR-4422	CLIP-seq
MIRT1120809	hsa-miR-4430	CLIP-seq
MIRT1120810	hsa-miR-4438	CLIP-seq
MIRT2264627	hsa-miR-4464	CLIP-seq
MIRT2264628	hsa-miR-4490	CLIP-seq
MIRT2264629	hsa-miR-4496	CLIP-seq
MIRT2264630	hsa-miR-449a	CLIP-seq
MIRT2264631	hsa-miR-449b	CLIP-seq
MIRT1120811	hsa-miR-4505	CLIP-seq
MIRT2264632	hsa-miR-4514	CLIP-seq
MIRT1120862	hsa-miR-4517	CLIP-seq
MIRT2264633	hsa-miR-4639-3p	CLIP-seq
MIRT2264634	hsa-miR-4644	CLIP-seq
MIRT2264635	hsa-miR-4645-5p	CLIP-seq
MIRT2264636	hsa-miR-4659a-3p	CLIP-seq
MIRT2264637	hsa-miR-4659b-3p	CLIP-seq
MIRT2264638	hsa-miR-4668-3p	CLIP-seq
MIRT2264639	hsa-miR-4670-3p	CLIP-seq
MIRT2264640	hsa-miR-4673	CLIP-seq
MIRT1120863	hsa-miR-4680-5p	CLIP-seq
MIRT1120864	hsa-miR-4687-3p	CLIP-seq
MIRT2264641	hsa-miR-4692	CLIP-seq
MIRT1120865	hsa-miR-4699-3p	CLIP-seq
MIRT2264642	hsa-miR-4701-3p	CLIP-seq
MIRT2264643	hsa-miR-4713-5p	CLIP-seq
MIRT2264644	hsa-miR-4723-3p	CLIP-seq
MIRT2264645	hsa-miR-4726-3p	CLIP-seq
MIRT2264646	hsa-miR-4732-5p	CLIP-seq
MIRT2264647	hsa-miR-4742-5p	CLIP-seq
MIRT2264648	hsa-miR-4748	CLIP-seq
MIRT1120866	hsa-miR-4749-3p	CLIP-seq
MIRT2264649	hsa-miR-4762-5p	CLIP-seq
MIRT2264650	hsa-miR-4773	CLIP-seq
MIRT2264651	hsa-miR-4795-5p	CLIP-seq
MIRT2264652	hsa-miR-4796-5p	CLIP-seq
MIRT2264653	hsa-miR-485-3p	CLIP-seq
MIRT2264654	hsa-miR-489	CLIP-seq
MIRT2264655	hsa-miR-495	CLIP-seq
MIRT1120869	hsa-miR-505	CLIP-seq
MIRT1120871	hsa-miR-509-3-5p	CLIP-seq
MIRT1120814	hsa-miR-5095	CLIP-seq
MIRT1120872	hsa-miR-509-5p	CLIP-seq
MIRT2264656	hsa-miR-511	CLIP-seq
MIRT2264657	hsa-miR-514	CLIP-seq
MIRT2264658	hsa-miR-514b-3p	CLIP-seq
MIRT2264659	hsa-miR-515-3p	CLIP-seq
MIRT1120815	hsa-miR-516b	CLIP-seq
MIRT2264660	hsa-miR-519e	CLIP-seq
MIRT2264661	hsa-miR-520d-5p	CLIP-seq
MIRT2264662	hsa-miR-524-5p	CLIP-seq
MIRT2264663	hsa-miR-532-3p	CLIP-seq
MIRT1120873	hsa-miR-543	CLIP-seq
MIRT1120874	hsa-miR-548ag	CLIP-seq
MIRT1120875	hsa-miR-548ai	CLIP-seq
MIRT2264664	hsa-miR-548l	CLIP-seq
MIRT2264665	hsa-miR-548o	CLIP-seq
MIRT2264666	hsa-miR-573	CLIP-seq
MIRT2264667	hsa-miR-576-5p	CLIP-seq
MIRT2264668	hsa-miR-600	CLIP-seq
MIRT1120880	hsa-miR-643	CLIP-seq
MIRT1120881	hsa-miR-647	CLIP-seq
MIRT2264669	hsa-miR-648	CLIP-seq
MIRT2264670	hsa-miR-654-3p	CLIP-seq
MIRT1120882	hsa-miR-758	CLIP-seq
MIRT2264671	hsa-miR-767-3p	CLIP-seq
MIRT2264672	hsa-miR-802	CLIP-seq
MIRT2264673	hsa-miR-936	CLIP-seq
MIRT2264674	hsa-miR-943	CLIP-seq
MIRT2264597	hsa-miR-198	CLIP-seq
MIRT1120806	hsa-miR-3652	CLIP-seq
MIRT1120809	hsa-miR-4430	CLIP-seq
MIRT2264635	hsa-miR-4645-5p	CLIP-seq
MIRT2264640	hsa-miR-4673	CLIP-seq
MIRT1120812	hsa-miR-4797-5p	CLIP-seq
MIRT2563525	hsa-miR-1273e	CLIP-seq
MIRT2563526	hsa-miR-1273g	CLIP-seq
MIRT2563527	hsa-miR-1276	CLIP-seq
MIRT2563528	hsa-miR-128	CLIP-seq
MIRT2264592	hsa-miR-135a	CLIP-seq
MIRT2264593	hsa-miR-135b	CLIP-seq
MIRT2563529	hsa-miR-145	CLIP-seq
MIRT2563530	hsa-miR-1825	CLIP-seq
MIRT2563531	hsa-miR-188-5p	CLIP-seq
MIRT2563532	hsa-miR-199a-5p	CLIP-seq
MIRT2563533	hsa-miR-199b-5p	CLIP-seq
MIRT2563534	hsa-miR-2052	CLIP-seq
MIRT2563535	hsa-miR-2113	CLIP-seq
MIRT2563536	hsa-miR-3180-5p	CLIP-seq
MIRT2563537	hsa-miR-3607-3p	CLIP-seq
MIRT2563538	hsa-miR-3692	CLIP-seq
MIRT2563539	hsa-miR-4311	CLIP-seq
MIRT2563540	hsa-miR-4313	CLIP-seq
MIRT2563541	hsa-miR-4423-5p	CLIP-seq
MIRT2264638	hsa-miR-4668-3p	CLIP-seq
MIRT1120797	hsa-miR-4724-5p	CLIP-seq
MIRT2563542	hsa-miR-4778-3p	CLIP-seq
MIRT2563543	hsa-miR-548c-3p	CLIP-seq
MIRT2563544	hsa-miR-579	CLIP-seq
MIRT2563545	hsa-miR-583	CLIP-seq
MIRT2563546	hsa-miR-599	CLIP-seq
MIRT2563547	hsa-miR-605	CLIP-seq
MIRT2563548	hsa-miR-924	CLIP-seq
MIRT2563525	hsa-miR-1273e	CLIP-seq
MIRT2563526	hsa-miR-1273g	CLIP-seq
MIRT2563528	hsa-miR-128	CLIP-seq
MIRT2264592	hsa-miR-135a	CLIP-seq
MIRT2264593	hsa-miR-135b	CLIP-seq
MIRT2563529	hsa-miR-145	CLIP-seq
MIRT2563530	hsa-miR-1825	CLIP-seq
MIRT2563532	hsa-miR-199a-5p	CLIP-seq
MIRT2563533	hsa-miR-199b-5p	CLIP-seq
MIRT2563534	hsa-miR-2052	CLIP-seq
MIRT2563535	hsa-miR-2113	CLIP-seq
MIRT2563536	hsa-miR-3180-5p	CLIP-seq
MIRT2563538	hsa-miR-3692	CLIP-seq
MIRT2563540	hsa-miR-4313	CLIP-seq
MIRT2563546	hsa-miR-599	CLIP-seq

Show/Hide all(19)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	14522076
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA	14522076
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	14522076
GO:0003677	Function	DNA binding	IDA	23099021
GO:0003725	Function	Double-stranded RNA binding	TAS	9671805
GO:0005515	Function	Protein binding	IPI	9671805, 10366446, 32814053
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	TAS	9671805
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	TAS	9671805
GO:0005886	Component	Plasma membrane	IDA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0032481	Process	Positive regulation of type I interferon production	TAS
GO:0042803	Function	Protein homodimerization activity	IDA	23099021
GO:0045296	Function	Cadherin binding	HDA	25468996
GO:0051092	Process	Positive regulation of NF-kappaB transcription factor activity	IEA

MIM	HGNC	e!Ensembl
603256	6702	ENSG00000124831

Protein

UniProt ID

Q32MZ4

Protein name

Leucine-rich repeat flightless-interacting protein 1 (LRR FLII-interacting protein 1) (GC-binding factor 2) (TAR RNA-interacting protein)

Protein function

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA re

PDB

4H22

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF09738	LRRFIP	23 → 353	LRRFIP family	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitously expressed. {ECO:0000269|PubMed:9671805, ECO:0000269|PubMed:9705290}.

Sequence

MTSPAAAQSREIDCLSPEAQKLAEARLAAKRAARAEAREIRMKELERQQKEEDSERYSRR
SRRNTSASDEDERMSVGSRGSLRVEERPEKDFTEKGSRNMPGLSAATLASLGGTSSRRGS
GDTSISIDTEASIREIKELNELKDQIQDVEGKYMQGLKEMKDSLAEVEEKYKKAMVSNAQ
LDNEKTNFMYQVDTLKDMLLELEEQLAESRRQYEEKNKEFEREKHAHSILQFQFAEVKEA
LKQREEMLEKHGIILNSEIATNGETSDTLNNVGYQGPTKMTKEELNALKSTGDGTLGRAS
EVEVKNEIVANVGKREILHNTEKEQHTEDTVKDCVDIEVFPAGENTEDQKSSEDTAPFLG
TLAGATYEEQVQSQILESSSLPENTVQVESNEVMGAPDDRTRTPLEPSNCWSDLDGGNHT
ENVGEAAVTQVEEQAGTVASCPLGHSDDTVYHDDKCMVEVPQELETSTGHSLEKEFTNQE
AAEPKEVPAHSTEVGRDHNEEEGEETGLRDEKPIKTEVPGSPAGTEGNCQEATGPSTVDT
QNEPLDMKEPDEEKSDQQGEALDSSQKKTKNKKKKNKKKKSPVPVETLKDVKKELTYQNT
DLSEIKEEEQVKSTDRKSAVEAQNEVTENPKQKIAAESSENVDCPENPKIKLDGKLDQEG
DDVQTAAEEVLADGDTLDFEDDTVQSSGPRAGGEELDEGVAKDNAKIDGATQSSPAEPKS
EDADRCTLPEHESPSQDISDACEAESTERCEMSEHPSQTVRKALDSNSLENDDLSAPGRE
PGHFNPESREDTRGGNEKGKSKEDCTMS

Sequence length

808

Interactions

View interactions

	Reactome
			Signaling by cytosolic FGFR1 fusion mutants LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Signaling by FGFR1 in disease

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158 View all (309 more)
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346 View all (12 more)	21795503

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Atrial Fibrillation	Atrial Fibrillation			GWAS

Show/Hide Text Mining Associations (14)

Disease Name	Relationship Type	References
Associations from Text Mining
Abdominal Injuries	Associate	23505185
Autism Spectrum Disorder	Associate	36938998
Breast Neoplasms	Associate	23181716
Carcinoma Hepatocellular	Associate	24761896
Colorectal Neoplasms	Associate	39596218
Coronary Artery Disease	Associate	34385509
COVID 19	Associate	35421082
Glioblastoma	Associate	25904638, 35338570
Glioma	Associate	35338570
Inflammation	Associate	23505185, 36938998
Myelodysplastic Syndromes	Associate	40420163
Neoplasms	Associate	23181716, 24761896
Neoplasms Adipose Tissue	Associate	23505185
Prostatic Neoplasms	Associate	36601001

LRRFIP1 (LRR binding FLII interacting protein 1)