NEK9 (NIMA related kinase 9)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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91754 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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NIMA related kinase 9 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NEK9 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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APUG, LCCS10, NC, NERCC, NERCC1 |
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Chromosome
Chromosome number
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14 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q24.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the NimA (never in mitosis A) family of serine/threonine protein kinases. The encoded protein is activated in mitosis and, in turn, activates other family members during mitosis. This protein also mediates cellular processes |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||
| UniProt ID | Q8TD19 | ||||||||||||||||||||||||||||||
| Protein name | Serine/threonine-protein kinase Nek9 (EC 2.7.11.1) (Nercc1 kinase) (Never in mitosis A-related kinase 9) (NimA-related protein kinase 9) (NimA-related kinase 8) (Nek8) | ||||||||||||||||||||||||||||||
| Protein function | Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation (PubMed:12101123, PubMed:12840024, PubMed:14660563, PubMed:19941817). Phosphorylates different histones, myelin basic protei | ||||||||||||||||||||||||||||||
| PDB | 3ZKE , 3ZKF | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts. {ECO:0000269|PubMed:11864968}. | ||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 979 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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