SLC60A2 (solute carrier family 60 member 2)

Gene

• Entrez ID: 91749
• Gene name: Solute carrier family 60 member 2
• Gene symbol: SLC60A2
• Synonyms (NCBI Gene): KIAA1919, MFSD4B, NaGLT1
• Chromosome: 6
• Chromosome location: 6q21

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT634611	hsa-miR-500b-3p	HITS-CLIP	23824327
MIRT634610	hsa-miR-5693	HITS-CLIP	23824327
MIRT634609	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT634608	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT634607	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT634606	hsa-miR-6773-3p	HITS-CLIP	23824327
MIRT634605	hsa-miR-215-3p	HITS-CLIP	23824327
MIRT634604	hsa-miR-767-5p	HITS-CLIP	23824327
MIRT634603	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT634602	hsa-miR-3135b	HITS-CLIP	23824327
MIRT634601	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT634600	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT634599	hsa-miR-593-5p	HITS-CLIP	23824327
MIRT634598	hsa-miR-3652	HITS-CLIP	23824327
MIRT634597	hsa-miR-4430	HITS-CLIP	23824327
MIRT634596	hsa-miR-6879-3p	HITS-CLIP	23824327
MIRT634595	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT634594	hsa-miR-891a-3p	HITS-CLIP	23824327
MIRT634593	hsa-miR-5698	HITS-CLIP	23824327
MIRT607836	hsa-miR-4438	HITS-CLIP	24906430
MIRT607835	hsa-miR-4269	HITS-CLIP	24906430
MIRT607834	hsa-miR-6715b-5p	HITS-CLIP	24906430
MIRT607833	hsa-miR-4740-3p	HITS-CLIP	24906430
MIRT607832	hsa-miR-4258	HITS-CLIP	24906430
MIRT607831	hsa-miR-6778-3p	HITS-CLIP	24906430
MIRT607830	hsa-miR-3199	HITS-CLIP	24906430
MIRT607829	hsa-miR-8052	HITS-CLIP	24906430
MIRT607828	hsa-miR-365a-5p	HITS-CLIP	24906430
MIRT607827	hsa-miR-365b-5p	HITS-CLIP	24906430
MIRT607826	hsa-miR-5095	HITS-CLIP	24906430
MIRT607825	hsa-miR-7151-3p	HITS-CLIP	24906430
MIRT449705	hsa-miR-4742-3p	PAR-CLIP	22100165
MIRT449704	hsa-miR-4524a-3p	PAR-CLIP	22100165
MIRT449703	hsa-miR-3672	PAR-CLIP	22100165
MIRT449702	hsa-miR-6864-3p	PAR-CLIP	22100165

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005355	Function	Glucose transmembrane transporter activity	IBA	21873635
GO:0005515	Function	Protein binding	IPI	32296183
GO:0006814	Process	Sodium ion transport	IEA
GO:0015293	Function	Symporter activity	IEA
GO:0016021	Component	Integral component of membrane	IEA
GO:0016324	Component	Apical plasma membrane	IEA
GO:1904659	Process	Glucose transmembrane transport	IEA

Other IDs

• MIM: 617331
• HGNC: 21053
• e!Ensembl: ENSG00000173214

Protein

• UniProt ID: Q5TF39
• Protein name: Sodium-dependent glucose transporter 1 (Major facilitator superfamily domain-containing protein 4B)
• Protein function: May function as a sodium-dependent glucose transporter. Potential channels for urea in the inner medulla of kidney.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07690	MFS_1	2 → 316	Major Facilitator Superfamily	Family

• Sequence:

  MLCASFLGLGLSVAIVGPTFQDLATNVNRNISSLSFIFVGRALGYLSGSVIGGFLVDVMN
  YFLLLGISMSATTVGLYLVPFCKTAILLTVMMSIFGVSIGILDTGGNVLILAIWGDKGAP
  HMQALHFSFALGAFLAPLLAKLALGPTASAENHTESDFHPALNQSSDADSEALFGVPNDK
  NLLWAYAVIGTYMFLVSVIFFCLFLKNSSKQEKARASAETFRRAKYHNALLCLLFLFFFF
  YVGAEVTYGSYVFSFATTHAGMKESEAAGLNSIFWGTFAACRGLAIFFATCLQPGTMIVL
  SNIGSLTSSLFLVLFDKNPICLWIATSVYGASMATTFPSGVSWIEQYTTIHGKSAAFFVI
  GASLGEMAIPAVIGILQGKYPDLPVVLYTSLGASIATGILFPVLYKLATSPLDRQRKEDR
  KSEDQKALLSSSGLNEYEEENEEEDAEKWNEMDFEMIETNDTMRHSIIETSRSSLTEPTA
  EVYNQYPSNALVFESSPFNTGSAHVKHLPETRTKGTNV

• Sequence length: 518

Pathways

Reactome:

Cellular hexose transport

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800, rs63750198, rs63751109, rs863223312, rs63750710, rs63751615, rs63750206, rs63750781, rs63750899, rs63750691, rs63750217, rs121912965, rs63749939, rs63751194, rs63750693, rs63750540, rs63751221, rs193922370, rs80359596, rs397514632, rs483352909, rs200495564, rs397514684, rs397516436, rs398122386, rs79512956, rs74953290, rs587779001, rs63750677, rs63749837, rs267607816, rs63751715, rs267607819, rs267607815, rs267607822, rs63749906, rs587778883, rs63750472, rs63751012, rs63750715, rs63750580, rs267607706, rs267607709, rs267607710, rs587778894, rs63750749, rs63750483, rs63751015, rs63751153, rs63751094, rs63751118, rs63750316, rs63749981, rs587778906, rs267607821, rs587778908, rs63750020, rs587778909, rs63750713, rs267607825, rs63751592, rs281864936, rs587778913, rs587778914, rs63749795, rs63750855, rs63749916, rs63749923, rs63751472, rs63751689, rs267607832, rs267607837, rs267607836, rs587778923, rs63750028, rs587778928, rs587778929, rs587778930, rs63751277, rs587778933, rs267607842, rs267607843, rs63750192, rs587778934, rs63750193, rs587778937, rs587778938, rs267607845, rs63751244, rs63751393, rs63751460, rs267607849, rs267607853, rs267607856, rs267607850, rs63751657, rs267607854, rs267607852, rs587778942, rs63750309, rs63750587, rs63749863, rs63751486, rs63750016, rs63749868, rs63750375, rs63750035, rs63750604, rs63750386, rs63750150, rs63750486, rs63751428, rs267607866, rs63749986, rs63751594, rs63750152, rs63750850, rs267607867, rs267607868, rs63751632, rs267607871, rs63751892, rs587778956, rs63750469, rs587778958, rs63749792, rs267607875, rs63751255, rs281864938, rs63751202, rs63750726, rs63751310, rs63749900, rs587778964, rs267607879, rs267607878, rs587778966, rs267607883, rs267607887, rs63750061, rs63750663, rs587778968, rs587778971, rs63750809, rs63749867, rs63750864, rs587778972, rs63751275, rs267607718, rs267607722, rs63750769, rs267607717, rs587778973, rs267607716, rs267607720, rs63749995, rs63750859, rs587778975, rs63750114, rs587778976, rs63750603, rs267607889, rs267607723, rs63750561, rs63750499, rs63751642, rs63751022, rs587778981, rs63750971, rs267607898, rs267607906, rs267607903, rs587778989, rs587778992, rs267607894, rs267607901, rs267607892, rs63750437, rs587778997, rs587778998, rs63750005, rs63750641, rs63751421, rs11541859, rs63750266, rs111052004, rs267607726, rs267607727, rs63750453, rs267607734, rs267607735, rs63751665, rs267607736, rs267607732, rs63749816, rs63750539, rs267607739, rs587779006, rs587779008, rs267607745, rs267607742, rs63751595, rs267607743, rs587779010, rs587779012, rs63750057, rs63749818, rs63751124, rs587779014, rs587779015, rs63749820, rs63751302, rs267607750, rs267607751, rs267607749, rs63750891, rs63749959, rs63749804, rs267607765, rs267607760, rs587779021, rs267607759, rs63750515, rs587779023, rs63751021, rs63751480, rs267607772, rs267607773, rs587779024, rs63751653, rs587779027, rs267607767, rs587779029, rs63750706, rs63750385, rs267607774, rs267607778, rs267607780, rs587779034, rs63751711, rs267607784, rs587779035, rs63750823, rs63750822, rs267607787, rs63750303, rs63749839, rs63749827, rs267607789, rs267607790, rs267607791, rs267607786, rs267607771, rs267607795, rs267607794, rs267607788, rs267607799, rs267607801, rs587779045, rs63750034, rs587779047, rs63750216, rs63751707, rs63751598, rs267607803, rs267607777, rs63750144, rs267607805, rs63750547, rs63750489, rs63750993, rs587779054, rs63751259, rs63749926, rs63750796, rs587779058, rs63750745, rs63750582, rs180177084, rs587779866, rs200389141, rs587779950, rs587780104, rs587780183, rs587778536, rs587780683, rs587781554, rs267607712, rs587777627, rs587783057, rs730881734, rs41542214, rs730881273, rs786203456, rs786201990, rs786202767, rs748005072, rs786204317, rs786204318, rs797045117, rs63750549, rs863225383, rs863225384, rs863225373, rs863225376, rs863225377, rs863225378, rs863225379, rs863225380, rs863225381, rs63750059, rs267607823, rs864622457, rs869312767, rs869312753, rs876661059, rs876658915, rs876658923, rs876660860, rs876660822, rs876660458, rs876660214, rs876658657, rs876658247, rs876659226, rs876658821, rs876660589, rs876659068, rs876659681, rs876659608, rs878853794, rs878853778, rs878853780, rs878853785, rs886039423, rs886039424, rs1057517543, rs1057517541, rs756843954, rs1057517617, rs1057517558, rs1057519256, rs1060500689, rs764085979, rs1060500707, rs1060500699, rs1060500706, rs1060500703, rs1064795341, rs1064793607, rs1064794348, rs1064795441, rs1064794373, rs1064793172, rs1064794122, rs1064795515, rs1064794331, rs63750978, rs1114167435, rs1553641362, rs63751448, rs1553648029, rs1553648058, rs587778903, rs1553653237, rs1553664353, rs267607744, rs1553647995, rs1553648047, rs1553653084, rs1553663750, rs1553664436, rs1553488015, rs1553637293, rs63750310, rs63750443, rs63751596, rs1553646681, rs550890395, rs1064796057, rs1553642079, rs1553648023, rs587782087, rs746536721, rs1553653037, rs1248251121, rs1553646602, rs1434898623, rs1553665683, rs1553648068, rs1553645331, rs1553644123, rs1553658246, rs1553651299, rs1553648149, rs1553663159, rs1302248679, rs1553664119, rs1553658009, rs1553665977, rs1416171624, rs1553663834, rs1553664617, rs1553664702, rs1553647969, rs1553648040, rs1437454428, rs1553641273, rs63751101, rs1553646764, rs1553648225, rs1554082118, rs1553648201, rs1553638868, rs1553665866, rs376736188, rs1553642707, rs1553645226, rs1553652883, rs63751435, rs1553653115, rs1553653195, rs63750300, rs1553662622, rs1553658104, rs1553648220, rs1559544064, rs63750584, rs267608083, rs1559551570, rs1559575107, rs1559553501, rs1565986506, rs1559524405, rs1559553492, rs1559554339, rs1559588540, rs1559558071, rs761329565, rs1559521039, rs1559574795, rs1567221417, rs1559578422, rs1481129490, rs1570714352, rs779783209, rs1575376830, rs1575469070, rs1575537843, rs1575620443, rs1575621506, rs587779022, rs1575414904, rs1575449093, rs1575469505, rs1575536254, rs1575537933, rs1575632112, rs1575639851, rs1575441094, rs1575449402, rs267607831, rs2081922847, rs2083403132, rs2085415927, rs2085469647, rs2043913790, rs147542208	27165003
Psoriasis	Psoriasis	rs281875215, rs587777763, rs281875213, rs281875212	20953190, 25903422, 25574825