RASL10B (RAS like family 10 member B)

Gene

• Entrez ID: 91608
• Gene name: RAS like family 10 member B
• Gene symbol: RASL10B
• Synonyms (NCBI Gene): RRP17, VTS58635
• Chromosome: 17
• Chromosome location: 17q12

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT043503	hsa-miR-331-3p	CLASH	23622248
MIRT039428	hsa-miR-421	CLASH	23622248
MIRT037118	hsa-miR-877-3p	CLASH	23622248
MIRT495291	hsa-miR-212-5p	PAR-CLIP	23708386
MIRT495290	hsa-miR-3926	PAR-CLIP	23708386
MIRT495289	hsa-miR-6069	PAR-CLIP	23708386
MIRT495288	hsa-miR-7156-3p	PAR-CLIP	23708386
MIRT495287	hsa-miR-548s	PAR-CLIP	23708386
MIRT495285	hsa-miR-4701-5p	PAR-CLIP	23708386
MIRT495286	hsa-miR-588	PAR-CLIP	23708386
MIRT495284	hsa-miR-4435	PAR-CLIP	23708386
MIRT495283	hsa-miR-3187-3p	PAR-CLIP	23708386
MIRT485155	hsa-miR-504-5p	PAR-CLIP	23592263
MIRT485153	hsa-miR-6732-3p	PAR-CLIP	23592263
MIRT485154	hsa-miR-4428	PAR-CLIP	23592263
MIRT485151	hsa-miR-4292	PAR-CLIP	23592263
MIRT485152	hsa-miR-6791-5p	PAR-CLIP	23592263
MIRT485150	hsa-miR-3192-5p	PAR-CLIP	23592263
MIRT485149	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT485147	hsa-miR-3656	PAR-CLIP	23592263
MIRT485148	hsa-miR-4533	PAR-CLIP	23592263
MIRT485146	hsa-miR-3202	PAR-CLIP	23592263
MIRT485145	hsa-miR-4434	PAR-CLIP	23592263
MIRT485144	hsa-miR-4516	PAR-CLIP	23592263
MIRT485143	hsa-miR-5703	PAR-CLIP	23592263
MIRT485142	hsa-miR-6827-5p	PAR-CLIP	23592263
MIRT485141	hsa-miR-6090	PAR-CLIP	23592263
MIRT485140	hsa-miR-4300	PAR-CLIP	23592263
MIRT485139	hsa-miR-5591-5p	PAR-CLIP	23592263
MIRT485138	hsa-miR-6726-5p	PAR-CLIP	23592263
MIRT485137	hsa-miR-920	PAR-CLIP	23592263
MIRT485136	hsa-miR-363-5p	PAR-CLIP	23592263
MIRT485135	hsa-miR-6745	PAR-CLIP	23592263
MIRT485134	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT495291	hsa-miR-212-5p	PAR-CLIP	23708386
MIRT495290	hsa-miR-3926	PAR-CLIP	23708386
MIRT495289	hsa-miR-6069	PAR-CLIP	23708386
MIRT495288	hsa-miR-7156-3p	PAR-CLIP	23708386
MIRT495287	hsa-miR-548s	PAR-CLIP	23708386
MIRT495285	hsa-miR-4701-5p	PAR-CLIP	23708386
MIRT495286	hsa-miR-588	PAR-CLIP	23708386
MIRT495284	hsa-miR-4435	PAR-CLIP	23708386
MIRT495283	hsa-miR-3187-3p	PAR-CLIP	23708386
MIRT485155	hsa-miR-504-5p	PAR-CLIP	23592263
MIRT485153	hsa-miR-6732-3p	PAR-CLIP	23592263
MIRT485154	hsa-miR-4428	PAR-CLIP	23592263
MIRT485151	hsa-miR-4292	PAR-CLIP	23592263
MIRT485152	hsa-miR-6791-5p	PAR-CLIP	23592263
MIRT485150	hsa-miR-3192-5p	PAR-CLIP	23592263
MIRT485149	hsa-miR-6770-5p	PAR-CLIP	23592263
MIRT485147	hsa-miR-3656	PAR-CLIP	23592263
MIRT485148	hsa-miR-4533	PAR-CLIP	23592263
MIRT485146	hsa-miR-3202	PAR-CLIP	23592263
MIRT485145	hsa-miR-4434	PAR-CLIP	23592263
MIRT485144	hsa-miR-4516	PAR-CLIP	23592263
MIRT485143	hsa-miR-5703	PAR-CLIP	23592263
MIRT485142	hsa-miR-6827-5p	PAR-CLIP	23592263
MIRT485141	hsa-miR-6090	PAR-CLIP	23592263
MIRT485140	hsa-miR-4300	PAR-CLIP	23592263
MIRT485139	hsa-miR-5591-5p	PAR-CLIP	23592263
MIRT485138	hsa-miR-6726-5p	PAR-CLIP	23592263
MIRT485137	hsa-miR-920	PAR-CLIP	23592263
MIRT485136	hsa-miR-363-5p	PAR-CLIP	23592263
MIRT485135	hsa-miR-6745	PAR-CLIP	23592263
MIRT485134	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT1292504	hsa-miR-1207-5p	CLIP-seq
MIRT1292505	hsa-miR-1294	CLIP-seq
MIRT1292506	hsa-miR-1321	CLIP-seq
MIRT1292507	hsa-miR-184	CLIP-seq
MIRT1292508	hsa-miR-1909	CLIP-seq
MIRT1292509	hsa-miR-2467-5p	CLIP-seq
MIRT1292510	hsa-miR-3188	CLIP-seq
MIRT1292511	hsa-miR-3616-3p	CLIP-seq
MIRT1292512	hsa-miR-3619-3p	CLIP-seq
MIRT1292513	hsa-miR-3975	CLIP-seq
MIRT1292514	hsa-miR-4257	CLIP-seq
MIRT1292515	hsa-miR-4284	CLIP-seq
MIRT1292516	hsa-miR-4316	CLIP-seq
MIRT1292517	hsa-miR-4419a	CLIP-seq
MIRT1292518	hsa-miR-4436b-3p	CLIP-seq
MIRT1292519	hsa-miR-4510	CLIP-seq
MIRT1292520	hsa-miR-4677-3p	CLIP-seq
MIRT1292521	hsa-miR-4736	CLIP-seq
MIRT1292522	hsa-miR-4739	CLIP-seq
MIRT1292523	hsa-miR-4756-5p	CLIP-seq
MIRT1292524	hsa-miR-4763-3p	CLIP-seq
MIRT1292525	hsa-miR-485-5p	CLIP-seq
MIRT1292526	hsa-miR-939	CLIP-seq
MIRT2086902	hsa-miR-1253	CLIP-seq
MIRT2086903	hsa-miR-1268	CLIP-seq
MIRT2086904	hsa-miR-1268b	CLIP-seq
MIRT2086905	hsa-miR-1299	CLIP-seq
MIRT2086906	hsa-miR-139-3p	CLIP-seq
MIRT1292509	hsa-miR-2467-5p	CLIP-seq
MIRT2086907	hsa-miR-378g	CLIP-seq
MIRT1292514	hsa-miR-4257	CLIP-seq
MIRT2086908	hsa-miR-4258	CLIP-seq
MIRT2086909	hsa-miR-4437	CLIP-seq
MIRT2086910	hsa-miR-4531	CLIP-seq
MIRT2086911	hsa-miR-4651	CLIP-seq
MIRT2086912	hsa-miR-4674	CLIP-seq
MIRT2086913	hsa-miR-4782-5p	CLIP-seq
MIRT2086914	hsa-miR-483-5p	CLIP-seq
MIRT2086915	hsa-miR-516b	CLIP-seq
MIRT2086916	hsa-miR-585	CLIP-seq
MIRT2086917	hsa-miR-592	CLIP-seq
MIRT2086918	hsa-miR-597	CLIP-seq
MIRT2086919	hsa-miR-608	CLIP-seq
MIRT2086920	hsa-miR-642b	CLIP-seq
MIRT2086921	hsa-miR-661	CLIP-seq
MIRT1292504	hsa-miR-1207-5p	CLIP-seq
MIRT1292507	hsa-miR-184	CLIP-seq
MIRT2311821	hsa-miR-1915	CLIP-seq
MIRT2311822	hsa-miR-194	CLIP-seq
MIRT2311823	hsa-miR-3184	CLIP-seq
MIRT2311824	hsa-miR-345	CLIP-seq
MIRT1292512	hsa-miR-3619-3p	CLIP-seq
MIRT2311825	hsa-miR-383	CLIP-seq
MIRT2311826	hsa-miR-423-5p	CLIP-seq
MIRT2311827	hsa-miR-4493	CLIP-seq
MIRT2311828	hsa-miR-4645-3p	CLIP-seq
MIRT2311829	hsa-miR-4688	CLIP-seq
MIRT2311830	hsa-miR-4726-3p	CLIP-seq
MIRT2311831	hsa-miR-4733-3p	CLIP-seq
MIRT1292521	hsa-miR-4736	CLIP-seq
MIRT1292524	hsa-miR-4763-3p	CLIP-seq
MIRT2311832	hsa-miR-4786-3p	CLIP-seq
MIRT2311833	hsa-miR-617	CLIP-seq
MIRT2311834	hsa-miR-671-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003050	Process	Regulation of systemic arterial blood pressure by atrial natriuretic peptide	IEA
GO:0003050	Process	Regulation of systemic arterial blood pressure by atrial natriuretic peptide	ISS
GO:0003924	Function	GTPase activity	IEA
GO:0003925	Function	G protein activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0005525	Function	GTP binding	IEA
GO:0005886	Component	Plasma membrane	IEA
GO:0016020	Component	Membrane	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0090277	Process	Positive regulation of peptide hormone secretion	IEA
GO:0090277	Process	Positive regulation of peptide hormone secretion	ISS

Other IDs

• MIM: 612128
• HGNC: 30295
• e!Ensembl: ENSG00000270885

Protein

• UniProt ID: Q96S79
• Protein name: Ras-like protein family member 10B (EC 3.6.5.2) (Ras-like protein VTS58635) (Ras-related protein 17) (RRP17)
• Protein function: May facilitate the release of atrial natriuretic peptide by cardiomyocytes and hence play a role in the regulation of arterial pressure.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00071	Ras	6 → 178	Ras family	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed at high levels in skeletal muscle and, at much lower levels, in heart, brain and pancreas. {ECO:0000269|PubMed:17984325}.
• Sequence:

  MVSTYRVAVLGARGVGKSAIVRQFLYNEFSEVCVPTTARRLYLPAVVMNGHVHDLQILDF
  PPISAFPVNTLQEWADTCCRGLRSVHAYILVYDICCFDSFEYVKTIRQQILETRVIGTSE
  TPIIIVGNKRDLQRGRVIPRWNVSHLVRKTWKCGYVECSAKYNWHILLLFSELLKSVGCA
  RCKHVHAALRFQGALRRNRCAIM

• Sequence length: 203