Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
91543
Gene name Gene Name - the full gene name approved by the HGNC.
Radical S-adenosyl methionine domain containing 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RSAD2
Synonyms (NCBI Gene) Gene synonyms aliases
SAND, cig33, cig5, vig1
Chromosome Chromosome number
2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
2p25.2
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is an interferon-inducible antiviral protein that belongs to the S-adenosyl-L-methionine (SAM) superfamily of enzymes. The protein plays a role in cellular antiviral response and innate immune signaling. Antiviral effects
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021222 hsa-miR-146a-5p Microarray 18057241
MIRT028788 hsa-miR-26b-5p Microarray 19088304
MIRT1320867 hsa-miR-106a CLIP-seq
MIRT1320868 hsa-miR-106b CLIP-seq
MIRT1320869 hsa-miR-1185 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0001650 Component Fibrillar center IDA
GO:0003824 Function Catalytic activity IEA
GO:0005515 Function Protein binding IPI 21527675, 21957124, 22045669, 23638199, 24245804, 32296183
GO:0005739 Component Mitochondrion IBA 21873635
GO:0005739 Component Mitochondrion IDA 21527675
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607810 30908 ENSG00000134321
Protein
UniProt ID Q8WXG1
Protein name S-adenosylmethionine-dependent nucleotide dehydratase RSAD2 (SAND) (EC 4.2.-.-) (Cytomegalovirus-induced gene 5 protein) (Radical S-adenosyl methionine domain-containing protein 2) (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-in
Protein function Interferon-inducible antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon (PubMed:31812350). Catalyzes the conversion of cytidine triphosphate (CTP) to 3'-deoxy-3',4'-didehydro-CTP (ddhC
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13353 Fer4_12 72 199 Domain
PF04055 Radical_SAM 77 266 Radical SAM superfamily Domain
Sequence
MWVLTPAAFAGKLLSVFRQPLSSLWRSLVPLFCWLRATFWLLATKRRKQQLVLRGPDETK
EEEEDPPLPTTPTSVNYHFTRQCNYKCGFCFHTAKTSFVLPLEEAKRGLLLLKEAGMEKI
NFSGGEPFLQDRGEYLGKLVRFCKVELRLPSVSIVSNGSLIRERWFQNYGEYLDILAISC
DSFDEEVNVLIGRGQGKKN
HVENLQKLRRWCRDYRVAFKINSVINRFNVEEDMTEQIKAL
NPVRWKVFQCLLIEGENCGEDALREA
ERFVIGDEEFERFLERHKEVSCLVPESNQKMKDS
YLILDEYMRFLNCRKGRKDPSKSILDVGVEEAIKFSGFDEKMFLKRGGKYIWSKADLKLD
W
Sequence length 361
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Hepatitis C
Influenza A
  Interferon alpha/beta signaling