Gene Gene information from NCBI Gene database.
Entrez ID 9145
Gene name Synaptogyrin 1
Gene symbol SYNGR1
Synonyms (NCBI Gene)
-
Chromosome 22
Chromosome location 22q13.1
Summary This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being re
miRNA miRNA information provided by mirtarbase database.
643
miRTarBase ID miRNA Experiments Reference
MIRT024495 hsa-miR-215-5p Microarray 19074876
MIRT026210 hsa-miR-192-5p Microarray 19074876
MIRT036022 hsa-miR-1301-3p CLASH 23622248
MIRT652943 hsa-miR-4759 HITS-CLIP 23824327
MIRT652944 hsa-miR-3169 HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
24
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956, 25910212, 32296183
GO:0005886 Component Plasma membrane TAS
GO:0006605 Process Protein targeting IEA
GO:0008021 Component Synaptic vesicle IEA
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603925 11498 ENSG00000100321
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O43759
Protein name Synaptogyrin-1
Protein function May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the re
PDB 8A6M
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01284 MARVEL 20 167 Membrane-associating domain Domain
Sequence
Sequence length 233
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
2
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
Prostate cancer Uncertain significance rs193920982 RCV000149346
Schizophrenia Benign rs57910921 RCV001258226
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Alzheimer Disease Associate 31699905
Arthritis Rheumatoid Associate 24532676, 26993500
Inflammation Associate 39953635
Liver Cirrhosis Biliary Associate 25690649, 26993500, 28425483
Lupus Erythematosus Systemic Associate 26808113
Ovarian Neoplasms Associate 30557369
Sjogren's Syndrome Associate 35896530
Squamous Cell Carcinoma of Head and Neck Associate 32155325
Stroke Associate 39953635