Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9145
Gene name Gene Name - the full gene name approved by the HGNC.
Synaptogyrin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SYNGR1
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q13.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes an integral membrane protein associated with presynaptic vesicles in neuronal cells. The exact function of this protein is unclear, but studies of a similar murine protein suggest that it functions in synaptic plasticity without being re
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT024495 hsa-miR-215-5p Microarray 19074876
MIRT026210 hsa-miR-192-5p Microarray 19074876
MIRT036022 hsa-miR-1301-3p CLASH 23622248
MIRT652943 hsa-miR-4759 HITS-CLIP 23824327
MIRT652944 hsa-miR-3169 HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956
GO:0005886 Component Plasma membrane TAS
GO:0006605 Process Protein targeting IEA
GO:0030285 Component Integral component of synaptic vesicle membrane IEA
GO:0030672 Component Synaptic vesicle membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
603925 11498 ENSG00000100321
Protein
UniProt ID O43759
Protein name Synaptogyrin-1
Protein function May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the re
PDB 8A6M
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01284 MARVEL 20 167 Membrane-associating domain Domain
Sequence
Sequence length 233
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neutrophil degranulation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Leukemia Leukemia, Myelocytic, Acute, Acute Myeloid Leukemia (AML-M2) rs121909646, rs121913488, rs587776834, rs752746786, rs869312821, rs767454740, rs1554564297 17330099
Rheumatoid arthritis Rheumatoid Arthritis rs587776843 24390342, 30423114, 24532676
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
16215643, 14732601, 17049558, 19665806, 19641478
Unknown
Disease term Disease name Evidence References Source
Bipolar Disorder bipolar disorder GenCC
Biliary Cholangitis Biliary Cholangitis GWAS
Biliary Cirrhosis Biliary Cirrhosis GWAS
Systemic lupus erythematosus Systemic lupus erythematosus GWAS
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 31699905
Arthritis Rheumatoid Associate 24532676, 26993500
Inflammation Associate 39953635
Liver Cirrhosis Biliary Associate 25690649, 26993500, 28425483
Lupus Erythematosus Systemic Associate 26808113
Ovarian Neoplasms Associate 30557369
Sjogren's Syndrome Associate 35896530
Squamous Cell Carcinoma of Head and Neck Associate 32155325
Stroke Associate 39953635