Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	91433
Gene name Gene Name - the full gene name approved by the HGNC.	RCC1 domain containing 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RCCD1
Synonyms (NCBI Gene) Gene synonyms aliases	-
Chromosome Chromosome number	15
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	15q26.1

Show/Hide all(269)

miRTarBase ID	miRNA	Experiments	Reference
MIRT044333	hsa-miR-106b-5p	CLASH	23622248
MIRT044333	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT141698	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT044333	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT141697	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT141717	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT141699	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT141723	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT141698	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT1298115	hsa-miR-105	CLIP-seq
MIRT1298116	hsa-miR-1207-3p	CLIP-seq
MIRT1298117	hsa-miR-1255a	CLIP-seq
MIRT1298118	hsa-miR-1255b	CLIP-seq
MIRT1298119	hsa-miR-1293	CLIP-seq
MIRT1298120	hsa-miR-140-3p	CLIP-seq
MIRT1298121	hsa-miR-142-5p	CLIP-seq
MIRT1298122	hsa-miR-186	CLIP-seq
MIRT1298123	hsa-miR-192	CLIP-seq
MIRT1298124	hsa-miR-215	CLIP-seq
MIRT1298125	hsa-miR-216a	CLIP-seq
MIRT1298126	hsa-miR-3121-3p	CLIP-seq
MIRT1298127	hsa-miR-3133	CLIP-seq
MIRT1298128	hsa-miR-3136-5p	CLIP-seq
MIRT1298129	hsa-miR-340	CLIP-seq
MIRT1298130	hsa-miR-3660	CLIP-seq
MIRT1298131	hsa-miR-4439	CLIP-seq
MIRT1298132	hsa-miR-4483	CLIP-seq
MIRT1298133	hsa-miR-4513	CLIP-seq
MIRT1298134	hsa-miR-4526	CLIP-seq
MIRT1298135	hsa-miR-4633-3p	CLIP-seq
MIRT1298136	hsa-miR-4639-5p	CLIP-seq
MIRT1298137	hsa-miR-4643	CLIP-seq
MIRT1298138	hsa-miR-4719	CLIP-seq
MIRT1298139	hsa-miR-4742-5p	CLIP-seq
MIRT1298140	hsa-miR-502-5p	CLIP-seq
MIRT1298141	hsa-miR-619	CLIP-seq
MIRT1298142	hsa-let-7a	CLIP-seq
MIRT1298143	hsa-let-7b	CLIP-seq
MIRT1298144	hsa-let-7c	CLIP-seq
MIRT1298145	hsa-let-7d	CLIP-seq
MIRT1298146	hsa-let-7e	CLIP-seq
MIRT1298147	hsa-let-7f	CLIP-seq
MIRT1298148	hsa-let-7g	CLIP-seq
MIRT1298149	hsa-let-7i	CLIP-seq
MIRT1298150	hsa-miR-1	CLIP-seq
MIRT1298115	hsa-miR-105	CLIP-seq
MIRT1298151	hsa-miR-106a	CLIP-seq
MIRT1298152	hsa-miR-106b	CLIP-seq
MIRT1298116	hsa-miR-1207-3p	CLIP-seq
MIRT1298153	hsa-miR-1228	CLIP-seq
MIRT1298117	hsa-miR-1255a	CLIP-seq
MIRT1298118	hsa-miR-1255b	CLIP-seq
MIRT1298154	hsa-miR-1273e	CLIP-seq
MIRT1298155	hsa-miR-1286	CLIP-seq
MIRT1298119	hsa-miR-1293	CLIP-seq
MIRT1298156	hsa-miR-1305	CLIP-seq
MIRT1298121	hsa-miR-142-5p	CLIP-seq
MIRT1298157	hsa-miR-17	CLIP-seq
MIRT1298122	hsa-miR-186	CLIP-seq
MIRT1298123	hsa-miR-192	CLIP-seq
MIRT1298158	hsa-miR-1972	CLIP-seq
MIRT1298159	hsa-miR-202	CLIP-seq
MIRT1298160	hsa-miR-2052	CLIP-seq
MIRT1298161	hsa-miR-206	CLIP-seq
MIRT1298162	hsa-miR-20a	CLIP-seq
MIRT1298163	hsa-miR-20b	CLIP-seq
MIRT1298124	hsa-miR-215	CLIP-seq
MIRT1298125	hsa-miR-216a	CLIP-seq
MIRT1298164	hsa-miR-2682	CLIP-seq
MIRT1298165	hsa-miR-3117-3p	CLIP-seq
MIRT1298126	hsa-miR-3121-3p	CLIP-seq
MIRT1298127	hsa-miR-3133	CLIP-seq
MIRT1298128	hsa-miR-3136-5p	CLIP-seq
MIRT1298166	hsa-miR-3140-5p	CLIP-seq
MIRT1298167	hsa-miR-3161	CLIP-seq
MIRT1298168	hsa-miR-3166	CLIP-seq
MIRT1298169	hsa-miR-3169	CLIP-seq
MIRT1298170	hsa-miR-3179	CLIP-seq
MIRT1298171	hsa-miR-3189-5p	CLIP-seq
MIRT1298172	hsa-miR-329	CLIP-seq
MIRT1298129	hsa-miR-340	CLIP-seq
MIRT1298173	hsa-miR-34c-3p	CLIP-seq
MIRT1298174	hsa-miR-3609	CLIP-seq
MIRT1298175	hsa-miR-3614-5p	CLIP-seq
MIRT1298176	hsa-miR-362-3p	CLIP-seq
MIRT1298130	hsa-miR-3660	CLIP-seq
MIRT1298177	hsa-miR-3661	CLIP-seq
MIRT1298178	hsa-miR-3673	CLIP-seq
MIRT1298179	hsa-miR-3925-3p	CLIP-seq
MIRT1298180	hsa-miR-3934	CLIP-seq
MIRT1298181	hsa-miR-4263	CLIP-seq
MIRT1298182	hsa-miR-4423-3p	CLIP-seq
MIRT1298183	hsa-miR-4436b-3p	CLIP-seq
MIRT1298131	hsa-miR-4439	CLIP-seq
MIRT1298184	hsa-miR-4458	CLIP-seq
MIRT1298132	hsa-miR-4483	CLIP-seq
MIRT1298185	hsa-miR-449c	CLIP-seq
MIRT1298186	hsa-miR-4500	CLIP-seq
MIRT1298187	hsa-miR-4509	CLIP-seq
MIRT1298133	hsa-miR-4513	CLIP-seq
MIRT1298134	hsa-miR-4526	CLIP-seq
MIRT1298188	hsa-miR-455-5p	CLIP-seq
MIRT1298135	hsa-miR-4633-3p	CLIP-seq
MIRT1298137	hsa-miR-4643	CLIP-seq
MIRT1298189	hsa-miR-4645-5p	CLIP-seq
MIRT1298190	hsa-miR-4673	CLIP-seq
MIRT1298191	hsa-miR-4678	CLIP-seq
MIRT1298192	hsa-miR-4685-5p	CLIP-seq
MIRT1298193	hsa-miR-4714-3p	CLIP-seq
MIRT1298194	hsa-miR-4717-5p	CLIP-seq
MIRT1298138	hsa-miR-4719	CLIP-seq
MIRT1298195	hsa-miR-4728-3p	CLIP-seq
MIRT1298196	hsa-miR-4744	CLIP-seq
MIRT1298197	hsa-miR-4758-3p	CLIP-seq
MIRT1298198	hsa-miR-4771	CLIP-seq
MIRT1298199	hsa-miR-4790-3p	CLIP-seq
MIRT1298200	hsa-miR-4795-3p	CLIP-seq
MIRT1298201	hsa-miR-4796-3p	CLIP-seq
MIRT1298202	hsa-miR-4799-5p	CLIP-seq
MIRT1298203	hsa-miR-485-3p	CLIP-seq
MIRT1298140	hsa-miR-502-5p	CLIP-seq
MIRT1298204	hsa-miR-519a	CLIP-seq
MIRT1298205	hsa-miR-519b-3p	CLIP-seq
MIRT1298206	hsa-miR-519c-3p	CLIP-seq
MIRT1298207	hsa-miR-519d	CLIP-seq
MIRT1298208	hsa-miR-548aa	CLIP-seq
MIRT1298209	hsa-miR-548ah	CLIP-seq
MIRT1298210	hsa-miR-576-5p	CLIP-seq
MIRT1298211	hsa-miR-606	CLIP-seq
MIRT1298212	hsa-miR-613	CLIP-seq
MIRT1298141	hsa-miR-619	CLIP-seq
MIRT1298213	hsa-miR-628-5p	CLIP-seq
MIRT1298214	hsa-miR-631	CLIP-seq
MIRT1298215	hsa-miR-636	CLIP-seq
MIRT1298216	hsa-miR-651	CLIP-seq
MIRT1298217	hsa-miR-664	CLIP-seq
MIRT1298218	hsa-miR-766	CLIP-seq
MIRT1298219	hsa-miR-888	CLIP-seq
MIRT1298220	hsa-miR-922	CLIP-seq
MIRT1298221	hsa-miR-93	CLIP-seq
MIRT1298222	hsa-miR-940	CLIP-seq
MIRT1298223	hsa-miR-98	CLIP-seq
MIRT1298128	hsa-miR-3136-5p	CLIP-seq
MIRT1298130	hsa-miR-3660	CLIP-seq
MIRT1298177	hsa-miR-3661	CLIP-seq
MIRT1298131	hsa-miR-4439	CLIP-seq
MIRT1298133	hsa-miR-4513	CLIP-seq
MIRT1298134	hsa-miR-4526	CLIP-seq
MIRT1298214	hsa-miR-631	CLIP-seq
MIRT1298128	hsa-miR-3136-5p	CLIP-seq
MIRT1298130	hsa-miR-3660	CLIP-seq
MIRT1298131	hsa-miR-4439	CLIP-seq
MIRT1298133	hsa-miR-4513	CLIP-seq
MIRT1298134	hsa-miR-4526	CLIP-seq
MIRT1298142	hsa-let-7a	CLIP-seq
MIRT1298143	hsa-let-7b	CLIP-seq
MIRT1298144	hsa-let-7c	CLIP-seq
MIRT1298145	hsa-let-7d	CLIP-seq
MIRT1298146	hsa-let-7e	CLIP-seq
MIRT1298147	hsa-let-7f	CLIP-seq
MIRT1298148	hsa-let-7g	CLIP-seq
MIRT1298149	hsa-let-7i	CLIP-seq
MIRT1298151	hsa-miR-106a	CLIP-seq
MIRT1298152	hsa-miR-106b	CLIP-seq
MIRT1298156	hsa-miR-1305	CLIP-seq
MIRT2088661	hsa-miR-150	CLIP-seq
MIRT1298157	hsa-miR-17	CLIP-seq
MIRT1298159	hsa-miR-202	CLIP-seq
MIRT1298162	hsa-miR-20a	CLIP-seq
MIRT1298163	hsa-miR-20b	CLIP-seq
MIRT2088662	hsa-miR-302a	CLIP-seq
MIRT2088663	hsa-miR-302b	CLIP-seq
MIRT2088664	hsa-miR-302c	CLIP-seq
MIRT2088665	hsa-miR-302d	CLIP-seq
MIRT2088666	hsa-miR-302e	CLIP-seq
MIRT1298165	hsa-miR-3117-3p	CLIP-seq
MIRT1298128	hsa-miR-3136-5p	CLIP-seq
MIRT1298168	hsa-miR-3166	CLIP-seq
MIRT2088667	hsa-miR-3199	CLIP-seq
MIRT1298173	hsa-miR-34c-3p	CLIP-seq
MIRT1298174	hsa-miR-3609	CLIP-seq
MIRT1298175	hsa-miR-3614-5p	CLIP-seq
MIRT1298130	hsa-miR-3660	CLIP-seq
MIRT2088668	hsa-miR-3667-5p	CLIP-seq
MIRT2088669	hsa-miR-372	CLIP-seq
MIRT2088670	hsa-miR-373	CLIP-seq
MIRT1298179	hsa-miR-3925-3p	CLIP-seq
MIRT1298180	hsa-miR-3934	CLIP-seq
MIRT1298181	hsa-miR-4263	CLIP-seq
MIRT1298131	hsa-miR-4439	CLIP-seq
MIRT1298184	hsa-miR-4458	CLIP-seq
MIRT1298186	hsa-miR-4500	CLIP-seq
MIRT1298187	hsa-miR-4509	CLIP-seq
MIRT1298133	hsa-miR-4513	CLIP-seq
MIRT1298134	hsa-miR-4526	CLIP-seq
MIRT1298191	hsa-miR-4678	CLIP-seq
MIRT1298192	hsa-miR-4685-5p	CLIP-seq
MIRT2088671	hsa-miR-4731-5p	CLIP-seq
MIRT1298196	hsa-miR-4744	CLIP-seq
MIRT1298198	hsa-miR-4771	CLIP-seq
MIRT1298200	hsa-miR-4795-3p	CLIP-seq
MIRT1298201	hsa-miR-4796-3p	CLIP-seq
MIRT1298202	hsa-miR-4799-5p	CLIP-seq
MIRT2088672	hsa-miR-512-3p	CLIP-seq
MIRT1298204	hsa-miR-519a	CLIP-seq
MIRT1298205	hsa-miR-519b-3p	CLIP-seq
MIRT1298206	hsa-miR-519c-3p	CLIP-seq
MIRT1298207	hsa-miR-519d	CLIP-seq
MIRT2088673	hsa-miR-520a-3p	CLIP-seq
MIRT2088674	hsa-miR-520b	CLIP-seq
MIRT2088675	hsa-miR-520c-3p	CLIP-seq
MIRT2088676	hsa-miR-520d-3p	CLIP-seq
MIRT2088677	hsa-miR-520e	CLIP-seq
MIRT2088678	hsa-miR-520g	CLIP-seq
MIRT2088679	hsa-miR-520h	CLIP-seq
MIRT1298209	hsa-miR-548ah	CLIP-seq
MIRT2088680	hsa-miR-552	CLIP-seq
MIRT1298210	hsa-miR-576-5p	CLIP-seq
MIRT1298216	hsa-miR-651	CLIP-seq
MIRT1298218	hsa-miR-766	CLIP-seq
MIRT1298221	hsa-miR-93	CLIP-seq
MIRT1298223	hsa-miR-98	CLIP-seq
MIRT1298150	hsa-miR-1	CLIP-seq
MIRT1298151	hsa-miR-106a	CLIP-seq
MIRT1298152	hsa-miR-106b	CLIP-seq
MIRT1298157	hsa-miR-17	CLIP-seq
MIRT1298161	hsa-miR-206	CLIP-seq
MIRT1298162	hsa-miR-20a	CLIP-seq
MIRT1298163	hsa-miR-20b	CLIP-seq
MIRT1298128	hsa-miR-3136-5p	CLIP-seq
MIRT1298168	hsa-miR-3166	CLIP-seq
MIRT1298170	hsa-miR-3179	CLIP-seq
MIRT1298173	hsa-miR-34c-3p	CLIP-seq
MIRT1298174	hsa-miR-3609	CLIP-seq
MIRT1298130	hsa-miR-3660	CLIP-seq
MIRT1298178	hsa-miR-3673	CLIP-seq
MIRT1298180	hsa-miR-3934	CLIP-seq
MIRT1298181	hsa-miR-4263	CLIP-seq
MIRT1298131	hsa-miR-4439	CLIP-seq
MIRT1298187	hsa-miR-4509	CLIP-seq
MIRT1298133	hsa-miR-4513	CLIP-seq
MIRT1298134	hsa-miR-4526	CLIP-seq
MIRT2088671	hsa-miR-4731-5p	CLIP-seq
MIRT1298196	hsa-miR-4744	CLIP-seq
MIRT1298198	hsa-miR-4771	CLIP-seq
MIRT1298201	hsa-miR-4796-3p	CLIP-seq
MIRT1298202	hsa-miR-4799-5p	CLIP-seq
MIRT1298204	hsa-miR-519a	CLIP-seq
MIRT1298205	hsa-miR-519b-3p	CLIP-seq
MIRT1298206	hsa-miR-519c-3p	CLIP-seq
MIRT1298207	hsa-miR-519d	CLIP-seq
MIRT1298209	hsa-miR-548ah	CLIP-seq
MIRT2088680	hsa-miR-552	CLIP-seq
MIRT1298210	hsa-miR-576-5p	CLIP-seq
MIRT1298212	hsa-miR-613	CLIP-seq
MIRT1298221	hsa-miR-93	CLIP-seq
MIRT2393594	hsa-miR-141	CLIP-seq
MIRT2393595	hsa-miR-200a	CLIP-seq
MIRT1298128	hsa-miR-3136-5p	CLIP-seq
MIRT1298130	hsa-miR-3660	CLIP-seq
MIRT2393596	hsa-miR-371b-5p	CLIP-seq
MIRT1298131	hsa-miR-4439	CLIP-seq
MIRT1298133	hsa-miR-4513	CLIP-seq
MIRT1298134	hsa-miR-4526	CLIP-seq
MIRT1298219	hsa-miR-888	CLIP-seq
MIRT2393594	hsa-miR-141	CLIP-seq
MIRT2393595	hsa-miR-200a	CLIP-seq
MIRT2393596	hsa-miR-371b-5p	CLIP-seq
MIRT1298219	hsa-miR-888	CLIP-seq

Show/Hide all(6)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	24981860, 33961781
GO:0005694	Component	Chromosome	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0006325	Process	Chromatin organization	IEA

MIM	HGNC	e!Ensembl
617997	30457	ENSG00000166965

Protein

UniProt ID

A6NED2

Protein name

RCC1 domain-containing protein 1

Protein function

Plays a role in transcriptional repression of satellite repeats, possibly by regulating H3K36 methylation levels in centromeric regions together with KDM8 (PubMed:24981860). Possibly together with KDM8, is involved in proper mitotic spindle orga

PDB

6F4R , 6F4S , 6F4T

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00415	RCC1	176 → 225	Regulator of chromosome condensation (RCC1) repeat	Repeat
PF00415	RCC1	318 → 369	Regulator of chromosome condensation (RCC1) repeat	Repeat

Sequence

MAEERPGAWFGFGFCGFGQELGSGRGRQVHSPSPLRAGVDICRVSASWSYTAFVTRGGRL
ELSGSASGAAGRCKDAWASEGLLAVLRAGPGPEALLQVWAAESALRGEPLWAQNVVPEAE
GEDDPAGEAQAGRLPLLPCARAYVSPRAPFYRPLAPELRARQLELGAEHALLLDAAGQVF
SWGGGRHGQLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESG
QLALPTRNLAEDGETVAREATELNEDGSQVKRTGGAEDGAPAPFIAVQPFPALLDLPMGS
DAVKASCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAVT
CGPWNTYVYAVEKGKS

Sequence length

376

Interactions

View interactions

Show/Hide Unknown Diseases (3)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Breast Cancer	Breast cancer	N/A	N/A	GWAS
Diabetes	Type 2 diabetes, Type 2 diabetes (PheCode 250.2)	N/A	N/A	GWAS
Prostate cancer	Prostate cancer	N/A	N/A	GWAS

Show/Hide Text Mining Associations (4)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Hereditary Breast and Ovarian Cancer Syndrome	Associate	27432226
Neoplasms	Associate	27432226
Ovarian Neoplasms	Associate	27432226
Pancreatic Neoplasms	Associate	31917448, 32907841

RCCD1 (RCC1 domain containing 1)