DDX60L (DExD/H-box 60 like)

Gene

• Entrez ID: 91351
• Gene name: DExD/H-box 60 like
• Gene symbol: DDX60L
• Synonyms (NCBI Gene): -
• Chromosome: 4
• Chromosome location: 4q32.3
• Summary: This gene encodes a member of the DExD/H-box helicase family of proteins, a subset of the super family 2 helicases. Members of the DExD/H-box helicase family share a conserved functional core comprised of two RecA-like globular domains. These domains cont

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT931344	hsa-miR-1270	CLIP-seq
MIRT931345	hsa-miR-3145-5p	CLIP-seq
MIRT931346	hsa-miR-3174	CLIP-seq
MIRT931347	hsa-miR-3187-3p	CLIP-seq
MIRT931348	hsa-miR-4434	CLIP-seq
MIRT931349	hsa-miR-4468	CLIP-seq
MIRT931350	hsa-miR-4516	CLIP-seq
MIRT931351	hsa-miR-4529-5p	CLIP-seq
MIRT931352	hsa-miR-4531	CLIP-seq
MIRT931353	hsa-miR-4536	CLIP-seq
MIRT931354	hsa-miR-4652-3p	CLIP-seq
MIRT931355	hsa-miR-4756-3p	CLIP-seq
MIRT931356	hsa-miR-4778-5p	CLIP-seq
MIRT931357	hsa-miR-513a-5p	CLIP-seq
MIRT931358	hsa-miR-620	CLIP-seq
MIRT931359	hsa-miR-921	CLIP-seq
MIRT1975629	hsa-miR-216a	CLIP-seq
MIRT1975630	hsa-miR-216b	CLIP-seq
MIRT1975631	hsa-miR-224	CLIP-seq
MIRT1975632	hsa-miR-23a	CLIP-seq
MIRT1975633	hsa-miR-23b	CLIP-seq
MIRT1975634	hsa-miR-23c	CLIP-seq
MIRT1975635	hsa-miR-3675-3p	CLIP-seq
MIRT1975636	hsa-miR-3691-3p	CLIP-seq
MIRT1975637	hsa-miR-4480	CLIP-seq
MIRT1975638	hsa-miR-4738-3p	CLIP-seq
MIRT1975639	hsa-miR-502-5p	CLIP-seq
MIRT1975640	hsa-miR-518a-5p	CLIP-seq
MIRT1975641	hsa-miR-527	CLIP-seq
MIRT1975642	hsa-miR-579	CLIP-seq
MIRT1975643	hsa-miR-664	CLIP-seq
MIRT2211153	hsa-miR-3612	CLIP-seq
MIRT2211154	hsa-miR-3652	CLIP-seq
MIRT2211155	hsa-miR-3690	CLIP-seq
MIRT2211156	hsa-miR-3977	CLIP-seq
MIRT2211157	hsa-miR-3978	CLIP-seq
MIRT2211158	hsa-miR-4254	CLIP-seq
MIRT2211159	hsa-miR-4430	CLIP-seq
MIRT2211160	hsa-miR-4443	CLIP-seq
MIRT931354	hsa-miR-4652-3p	CLIP-seq
MIRT2211161	hsa-miR-485-5p	CLIP-seq
MIRT2211162	hsa-miR-650	CLIP-seq
MIRT2211163	hsa-miR-875-3p	CLIP-seq
MIRT2448143	hsa-miR-3655	CLIP-seq
MIRT2448144	hsa-miR-593	CLIP-seq
MIRT2515040	hsa-miR-1284	CLIP-seq
MIRT2515041	hsa-miR-27a	CLIP-seq
MIRT2515042	hsa-miR-27b	CLIP-seq
MIRT2515043	hsa-miR-3129-3p	CLIP-seq
MIRT2515044	hsa-miR-323-3p	CLIP-seq
MIRT2515045	hsa-miR-3616-3p	CLIP-seq
MIRT2515046	hsa-miR-4427	CLIP-seq
MIRT2515047	hsa-miR-4436b-3p	CLIP-seq
MIRT2515048	hsa-miR-4452	CLIP-seq
MIRT2515049	hsa-miR-4680-3p	CLIP-seq
MIRT2515050	hsa-miR-4721	CLIP-seq
MIRT2515051	hsa-miR-4735-5p	CLIP-seq
MIRT1975638	hsa-miR-4738-3p	CLIP-seq
MIRT2515052	hsa-miR-4775	CLIP-seq
MIRT931357	hsa-miR-513a-5p	CLIP-seq
MIRT2515053	hsa-miR-548aa	CLIP-seq
MIRT2515054	hsa-miR-548ac	CLIP-seq
MIRT2515055	hsa-miR-548d-3p	CLIP-seq
MIRT2515056	hsa-miR-548z	CLIP-seq
MIRT2515057	hsa-miR-587	CLIP-seq
MIRT2515058	hsa-miR-590-3p	CLIP-seq
MIRT2515059	hsa-miR-606	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	IEA
GO:0003724	Function	RNA helicase activity	IEA
GO:0003725	Function	Double-stranded RNA binding	IBA
GO:0003727	Function	Single-stranded RNA binding	IBA
GO:0004386	Function	Helicase activity	IEA
GO:0005524	Function	ATP binding	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0016787	Function	Hydrolase activity	IEA
GO:0016887	Function	ATP hydrolysis activity	IEA
GO:0051607	Process	Defense response to virus	IBA

Other IDs

• MIM: 616725
• HGNC: 26429
• e!Ensembl: ENSG00000181381

Protein

• UniProt ID: Q5H9U9
• Protein name: Probable ATP-dependent RNA helicase DDX60-like (EC 3.6.4.13) (DEAD box protein 60-like)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00270	DEAD	745 → 908	DEAD/DEAH box helicase	Domain
  PF00271	Helicase_C	1206 → 1314	Helicase conserved C-terminal domain	Family

• Sequence:

  MGSKDHAVFFREMTQLILNEMPKAGYSSILNDFVESNFFVIDGDSLLVTCLGVKSFKWGQ
  NLHFFYLVECYLVDLLSNGGQFTIVFFKDAEYAYFDFPELLSLRTALILHLQHNTNIDVQ
  TEFSGCLSQDWKLFLEQHYPYFLIVSEEGLSDLQTYLFNFLIIHSWGMKVNVVLSSGHES
  DTLRFYAYTMESTDRNQTFSKENETVIQSAYKSLIQHLEEIRVLVLATHFEHLKWNDMME
  EAYQTLFLLQHLWSEGSDIQRVLCVTSCSLSLRMYHRVLVHSNCLSLQEVEDFCRLRCLC
  VAFQLHLPLSQRACSRVITCSWIRNSDSFLKMNKWCEYFILSNLNVFGCWNLNLNHVSDL
  YDEQLLKNIAFYYEFESTQEPHLNLGDSIRRDYEDLWNVVSHLVKEFNVGKSFPLRTTRR
  HFLRQEKSVIQEISLEKMPSVGFIPMTSAVIDEFVGDMMKDLPILKSDDPVVPSLFKQKT
  SDELLHWHAQRLLSDDYDRIKCHVDEQSRDPHVLDFLKKIQDYQQFYGKSLESISTKVIV
  TQTTRPKEDSSGASGEILQNTKPHQITKKSKKKSFLKEDQNKAQQNDDLLFSIEEEMKNN
  LHSGIRKLEDYLTSCASNSVKFGVEMLGLIACFKAWKKHCRGEGKISKDLSIAVQMMKRI
  HSLLERYPEILEAEHHQYIAKCLKYLGFNDLANSLDPTLIGDDKNKKKYSIDIGPARFQL
  QYMGHYLIRDERKDRDPRVQDFIPNAWQQELLDVVDKNESAVIVAPTSSGKTYASYYCME
  KVLRESDVGVVVYVAPAKSLVGQVAATVENRFTKTLPAGRTLCGAFTRDYCHNVLNCQVL
  ITVPECFEILLLAPHRQKWVERIRYVIFDEVHYLGREVGAKFWELLLVIIRCPFLVLSAT
  INNPNLLTKWLQSVKQYWKQADKIMEEKCISEKQADKCLNFLQDHSYKNQSYEVRLVLYG
  ERYNDLEKHICSVKHDDVYFDHFHPCAALTTDIIEKYGFPPDLTLTPQESIQLYDTMAQV
  WETWPRAQELCPEEFILFKNKIVIKKLDARKYEENLKAELTNWIKNGQVKKVKRVLKNLS
  PDSLSSSKDMVKMFPLLVEKLRQMDKLPAIFFLFKNDDVGKRAGSVCTFLEKTETKSHPH
  TECHSYVFAIDEVLEKVRKTQKRITKKNPKKAEKLERKKVYRAEYINFLENLKILEISED
  CTYADVKALHTEITRNKDSTLERVLPRVRFTRHGKELKALAQRGIGYHHSSMYFKEKEFV
  EILFVKGLIRVVTATETLALGIHMPCKSVVFAQDSVYLDALNYRQMSGRAGRRGQDLLGN
  VYFFDIPLPKIKRLLASSVPELRGQFPLSITLVLRLMLLASKGDDPEDAKAKVLSVLKHS
  LLSFKRRRAMETLKLYFLFSLQLLIKEDYLNKKGNPKKFAGLASYLHGHEPSNLVFVNFL
  KRGLFHNLCKPAWKGSQQFSQDVMEKLVLVLANLFGRKYIPAKFQNANLSFSQSKVILAE
  LPEDFKAALYEYNLAVMKDFASFLLIASKSVNMKKEHQLPLSRIKFTGKECEDSQLVSHL
  MSCKKGRVAISPFVCLSGNTDNDLLRPETINQVILRTVGVSGTQAPLLWPWKLDNRGRRM
  PLNAYVLNFYKHNCLTRLDQKNGMRMGQLLKCLKDFAFNIQAISDSLSELCENKRDNVVL
  AFKQLSQTFYEKLQEMQIQMSQNHLE

• Sequence length: 1706

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Associated diseases

Unknown
Disease merge term	Disease name	Evidence	References	Source
Psoriasis	Psoriasis	N/A	N/A	GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Aneuploidy	Associate	35347416
Carcinoma Pancreatic Ductal	Associate	34789165
Hepatitis C	Associate	26269178