Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	91289
Gene name	Lipase maturation factor 2
Gene symbol	LMF2
Synonyms (NCBI Gene)	TMEM112BTMEM153
Chromosome	22
Chromosome location	22q13.33

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miRTarBase ID	miRNA	Experiments	Reference
MIRT031477	hsa-miR-16-5p	Proteomics	18668040
MIRT047491	hsa-miR-10b-5p	CLASH	23622248
MIRT046231	hsa-miR-27b-3p	CLASH	23622248
MIRT713392	hsa-miR-3126-5p	HITS-CLIP	19536157
MIRT713391	hsa-miR-6875-5p	HITS-CLIP	19536157
MIRT713392	hsa-miR-3126-5p	HITS-CLIP	19536157
MIRT713391	hsa-miR-6875-5p	HITS-CLIP	19536157
MIRT1111534	hsa-miR-1238	CLIP-seq
MIRT1111535	hsa-miR-124	CLIP-seq
MIRT1111536	hsa-miR-128	CLIP-seq
MIRT1111537	hsa-miR-1343	CLIP-seq
MIRT1111538	hsa-miR-3652	CLIP-seq
MIRT1111539	hsa-miR-3676	CLIP-seq
MIRT1111540	hsa-miR-3714	CLIP-seq
MIRT1111541	hsa-miR-3910	CLIP-seq
MIRT1111542	hsa-miR-4421	CLIP-seq
MIRT1111543	hsa-miR-4430	CLIP-seq
MIRT1111544	hsa-miR-4505	CLIP-seq
MIRT1111545	hsa-miR-4640-5p	CLIP-seq
MIRT1111546	hsa-miR-4691-5p	CLIP-seq
MIRT1111547	hsa-miR-4705	CLIP-seq
MIRT1111548	hsa-miR-4726-5p	CLIP-seq
MIRT1111549	hsa-miR-506	CLIP-seq
MIRT2031137	hsa-miR-3190	CLIP-seq
MIRT2031138	hsa-miR-4645-3p	CLIP-seq
MIRT2031139	hsa-miR-4699-5p	CLIP-seq
MIRT2031140	hsa-miR-4757-3p	CLIP-seq
MIRT2031141	hsa-miR-7	CLIP-seq
MIRT1111535	hsa-miR-124	CLIP-seq
MIRT2261881	hsa-miR-1254	CLIP-seq
MIRT1111536	hsa-miR-128	CLIP-seq
MIRT2261882	hsa-miR-1289	CLIP-seq
MIRT1111537	hsa-miR-1343	CLIP-seq
MIRT2261883	hsa-miR-138	CLIP-seq
MIRT2261884	hsa-miR-1587	CLIP-seq
MIRT2261885	hsa-miR-2392	CLIP-seq
MIRT2261886	hsa-miR-3116	CLIP-seq
MIRT2261887	hsa-miR-3150a-3p	CLIP-seq
MIRT2261888	hsa-miR-3175	CLIP-seq
MIRT2261889	hsa-miR-3184	CLIP-seq
MIRT2031137	hsa-miR-3190	CLIP-seq
MIRT2261890	hsa-miR-3611	CLIP-seq
MIRT2261891	hsa-miR-3622b-5p	CLIP-seq
MIRT2261892	hsa-miR-3650	CLIP-seq
MIRT1111538	hsa-miR-3652	CLIP-seq
MIRT1111540	hsa-miR-3714	CLIP-seq
MIRT1111541	hsa-miR-3910	CLIP-seq
MIRT2261893	hsa-miR-423-5p	CLIP-seq
MIRT2261894	hsa-miR-4253	CLIP-seq
MIRT1111543	hsa-miR-4430	CLIP-seq
MIRT2261895	hsa-miR-4436b-3p	CLIP-seq
MIRT2261896	hsa-miR-4492	CLIP-seq
MIRT2261897	hsa-miR-4498	CLIP-seq
MIRT1111544	hsa-miR-4505	CLIP-seq
MIRT2261898	hsa-miR-4509	CLIP-seq
MIRT2031138	hsa-miR-4645-3p	CLIP-seq
MIRT2261899	hsa-miR-4656	CLIP-seq
MIRT2261900	hsa-miR-4667-5p	CLIP-seq
MIRT2261901	hsa-miR-4675	CLIP-seq
MIRT2261902	hsa-miR-4688	CLIP-seq
MIRT2031139	hsa-miR-4699-5p	CLIP-seq
MIRT2261903	hsa-miR-4700-5p	CLIP-seq
MIRT2261904	hsa-miR-4728-5p	CLIP-seq
MIRT2261905	hsa-miR-4741	CLIP-seq
MIRT2261906	hsa-miR-4744	CLIP-seq
MIRT2031140	hsa-miR-4757-3p	CLIP-seq
MIRT1111549	hsa-miR-506	CLIP-seq
MIRT2031141	hsa-miR-7	CLIP-seq
MIRT2261907	hsa-miR-762	CLIP-seq
MIRT2261908	hsa-miR-939	CLIP-seq
MIRT2561815	hsa-miR-1207-5p	CLIP-seq
MIRT2561816	hsa-miR-1909	CLIP-seq
MIRT2561817	hsa-miR-1915	CLIP-seq
MIRT2561818	hsa-miR-3202	CLIP-seq
MIRT2561819	hsa-miR-4271	CLIP-seq
MIRT2261895	hsa-miR-4436b-3p	CLIP-seq
MIRT2561820	hsa-miR-4685-5p	CLIP-seq
MIRT2561821	hsa-miR-4690-3p	CLIP-seq
MIRT2561822	hsa-miR-4725-3p	CLIP-seq
MIRT2561823	hsa-miR-4747-5p	CLIP-seq
MIRT2561824	hsa-miR-4763-3p	CLIP-seq
MIRT2561815	hsa-miR-1207-5p	CLIP-seq
MIRT2561816	hsa-miR-1909	CLIP-seq
MIRT2561817	hsa-miR-1915	CLIP-seq
MIRT2261895	hsa-miR-4436b-3p	CLIP-seq
MIRT2561820	hsa-miR-4685-5p	CLIP-seq
MIRT2561821	hsa-miR-4690-3p	CLIP-seq
MIRT2561824	hsa-miR-4763-3p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IBA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0016020	Component	Membrane	IEA
GO:0051604	Process	Protein maturation	IBA
GO:0051604	Process	Protein maturation	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q9BU23

Protein name

Lipase maturation factor 2 (Transmembrane protein 112B) (Transmembrane protein 153)

Protein function

Involved in the maturation of specific proteins in the endoplasmic reticulum. May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF06762	LMF1	122 → 590	Lipase maturation factor	Family

Sequence

MAGSRLPRQLFLQGVAAVFMFAFASLYTQIPGLYGPEGILPARRTLRPQGKGRWQQLWET
PTLLWEAPRLGLDTAQGLELLSLLGALVALGALLLSPLRHPVIYLLLWAAYLSACQVGQV
FLYFQWDSLLLETGFLAVLVAPLRPASHRKEAPQGRQAGALPHEDLPFWLVRWLLFRLMF
ASGVVKLTSRCPAWWGLTALTYHYETQCLPTPAAWFAHHLPVWLHKLSVVATFLIEIAVP
PLFFAPIRRLRLAAFYSQVLLQVLIIITGNYNFFNLMTLVLTTALLDDQHLAAEPGHGSR
KKTATSWPKALLATLSLLLELAVYGLLAYGTVHYFGLEVDWQQRTIHSRTTFTFHQFSQW
LKTLTLPTVWLGVASLVWELLSALWRWTQVRGWLRKLSAVVQLSLVGTATVALFLISLVP
YSYVEPGTHGRLWTGAHRLFGAVEHLQLANSYGLFRRMTGLGGRPEVVLEGSYDGHHWTE
IEFMYKPGNLSRPPPVVVPHQPRLDWQMWFAALGPHTHSPWFTSLVLRLLQGKEPVIRLV
QSQVARYPFHKQPPTYVRAQRYKYWFSQPGEQGQWWRRQWVEEFFPSVSLGDPTLETLLR
QFGLQEKSPPRTRSANSTLAQALHWTRSQLSPLEAPALLWGLLMAVGAVRFVQALLAPCS
LRSSPLAPVSGEKRRPASQKDSGAASEQATAAPNPCSSSSRTTRRKK

Sequence length

707

Interactions

View interactions

	Reactome
			Assembly of active LPL and LIPC lipase complexes

LMF2 (lipase maturation factor 2)