Gene Gene information from NCBI Gene database.
Entrez ID 91120
Gene name Zinc finger protein 682
Gene symbol ZNF682
Synonyms (NCBI Gene)
BC39498_3
Chromosome 19
Chromosome location 19p12
miRNA miRNA information provided by mirtarbase database.
669
miRTarBase ID miRNA Experiments Reference
MIRT050232 hsa-miR-25-3p CLASH 23622248
MIRT508748 hsa-miR-106a-5p HITS-CLIP 23313552
MIRT508747 hsa-miR-106b-5p HITS-CLIP 23313552
MIRT508746 hsa-miR-17-5p HITS-CLIP 23313552
MIRT508745 hsa-miR-20a-5p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O95780
Protein name Zinc finger protein 682
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 3 44 KRAB box Family
PF00096 zf-C2H2 173 195 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 229 251 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 285 307 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 313 335 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 341 363 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 369 391 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 425 447 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 453 474 Zinc finger, C2H2 type Domain
Sequence
MELLTFRDVTIEFSLEEWEFLNPAQQSLYRKVMLENYRNLVSLGLTVSKPELISRLEQRQ
EPWNVKRHETIAKPPAMSSHYTEDLLPEQCMQDSFQKVILRRYGSCGLEDLHLRKDGENV
GECKDQKEIYNGLNQCLSTLPSKIFPYNKCVKVFSKSSNLNRENIRHTTEKLFKCMQCGK
VFKSHSGLSYHKIIH
TEEKLCICEECGKTFKWFSYLTKHKRIHTGEKPYKCEECGKAFNW
CSSLTKHKRIH
TGEKPYKCEECGKAFHWCSPFVRHKKIHTGEKPYTCEDCGRAFNRHSHL
TKHKTIH
TGKKPYKCKECGKAFNHCSLLTIHERTHTGEKPYKCEECGKAFNSSSILTEHK
VIH
SGEKPYKCEKCDKVFKRFSYLTKHKRIHTGEKPYKCEECGKAFNWSSILTEHKRIHT
GEKPYNCEECGKAFNRCSHLTRHKKIHTAVKRYKCEECGKAFKRCSHLNEHKRVQRGEKS
CKYKKCGEAFNHCSNLTT
Sequence length 498
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
TYPE 2 DIABETES MELLITUS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Adenocarcinoma of Lung Associate 38111060
★☆☆☆☆
Found in Text Mining only