DPP9 (dipeptidyl peptidase 9)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 91039 |
| Gene name | Dipeptidyl peptidase 9 |
| Gene symbol | DPP9 |
| Synonyms (NCBI Gene) |
DP9DPLP9DPP IXDPRP-2DPRP2HATISIMD111
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| Chromosome | 19 |
| Chromosome location | 19p13.3 |
| Summary | This gene encodes a protein that is a member of the S9B family in clan SC of the serine proteases. The protein has been shown to have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Although the |
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miRNA
miRNA information provided by mirtarbase database.
416
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q86TI2 | |||||||||||||||
| Protein name | Dipeptidyl peptidase 9 (DP9) (EC 3.4.14.5) (Dipeptidyl peptidase IV-related protein 2) (DPRP-2) (Dipeptidyl peptidase IX) (DPP IX) (Dipeptidyl peptidase-like protein 9) (DPLP9) | |||||||||||||||
| Protein function | Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2 (PubMed:12662155, PubMed:16475979, PubMed:19667070, PubMed:29382749, PubMed:30291141, PubMed:33731929, PubMed:36112693). Acts as | |||||||||||||||
| PDB | 6EOQ , 6EOR , 6QZV , 6X6A , 6X6C , 7A3F , 7JKQ , 7JN7 , 7SVL , 7SVN , 7ZXS | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitously expressed, with highest levels in liver, heart and muscle, and lowest levels in brain. {ECO:0000269|PubMed:12459266, ECO:0000269|PubMed:12662155, ECO:0000269|PubMed:15245913}. | |||||||||||||||
| Sequence |
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| Sequence length | 863 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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