Gene Gene information from NCBI Gene database.
Entrez ID 90874
Gene name Zinc finger protein 697
Gene symbol ZNF697
Synonyms (NCBI Gene)
ZFP697
Chromosome 1
Chromosome location 1p12
miRNA miRNA information provided by mirtarbase database.
380
miRTarBase ID miRNA Experiments Reference
MIRT1535998 hsa-let-7a CLIP-seq
MIRT1535999 hsa-let-7b CLIP-seq
MIRT1536000 hsa-let-7c CLIP-seq
MIRT1536001 hsa-let-7d CLIP-seq
MIRT1536002 hsa-let-7e CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 32814053
GO:0005634 Component Nucleus IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
620981 32034 ENSG00000143067
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q5TEC3
Protein name Zinc finger protein 697
Protein function RNA-interacting protein with a high number of miRNA targets. Acts as a damage-induced regulator of muscle remodeling by mediating the interferon gamma response in muscle cells.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 261 283 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 290 311 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 317 339 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 353 375 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 383 403 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 409 431 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 437 459 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 465 487 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 493 515 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 521 543 Zinc finger, C2H2 type Domain
Sequence
MKQEDNQGVCAHQDSEDKGMGSDFEDSEDREGDPEEREMGSNPHDTNKREGHPEPEMGSN
PQDSRHREAVPDICTEGQLSEEEGVSVRGEEDDQSGVADMAMFPGLSESDSISRSLREDD
DESAGENRLEEEEEQPAPPVLPWRRHLSLGSRHRGDKPAHRRFHRLHHPMAVDLGELDSL
VASIMDAPTICPDCGESFSPGAAFLQHQRIHRLAEAAAAASLEPFGLAGECDAMVGMMGV
GVAGGFGAGPPLARPPREKPFRCGECGKGFSRNTYLTNHLRLHTGERPNLCADCGKSFSW
RADLLKHRRLH
TGEKPYPCPECGEAFSLSSHLLSHRRAHAAASGAGAAALRPFACGECGK
GFVRRSHLANHQRIH
TGEKPHGCGECGKRFSWRSDLVKHQRVHTGEKPYMCSECGETFSV
SSHLFTHKRTH
SGERPYVCRECGKGFGRNSHLVNHLRVHTGEKPFRCGQCEKRFSDFSTL
TQHQRTH
TGEKPYTCIECGKSFIQSSHLIRHRRIHTGNKPHKCAGCGKGFRYKTHLAQHQ
KLH
LC
Sequence length 545
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
4
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
OSTEOARTHRITIS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, HIP GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
OSTEOARTHRITIS, KNEE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
SYSTEMIC LUPUS ERYTHEMATOSUS GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations