LRRC46 (leucine rich repeat containing 46)

Gene
Gene miRNA Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
90506
Gene name Gene Name - the full gene name approved by the HGNC.
Leucine rich repeat containing 46
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
LRRC46
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
17q21.32
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Other IDs Protein Associated diseases
Show/Hide all(21)
miRTarBase ID miRNA Experiments Reference
MIRT1119660 hsa-miR-1262 CLIP-seq
MIRT1119661 hsa-miR-337-3p CLIP-seq
MIRT1119662 hsa-miR-4481 CLIP-seq
MIRT1119663 hsa-miR-4701-3p CLIP-seq
MIRT1119664 hsa-miR-4745-5p CLIP-seq
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
620927 25047 ENSG00000141294
Protein
Gene miRNA Other IDs Protein Associated diseases
UniProt ID Q96FV0
Protein name Leucine-rich repeat-containing protein 46
Protein function Required for normal spermatogenesis and male fertility. Plays an important role in sperm flagellum biogenesis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13855 LRR_8 44 → 100 Leucine rich repeat Repeat
Sequence 
MSGGKSAQGPEEGGVCITEALITKRNLTFPEDGELSEKMFHTLDELQTVRLDREGITTIR
NLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSEN
LIETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVVERWISDEEDE
ASSDEEFPELSGPFCSERGFLKELEQELSRHREHRQQTALTEHLLRMEMQPTLTDLPLLP
GVPMAGDSSPSATPAQGEETVPEAVSSPQASSPTKKPCSLIPRGHQSSFWGRKGARAATA
PKASVAEAPSTTKTTAKRSKK
Sequence length 321
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Other IDs Protein Associated diseases
Show/Hide Causal Diseases (1)
Causal
Disease term Disease name dbSNP ID References
Ovarian cancer Malignant neoplasm of ovary rs34424986, rs137853060, rs28934575, rs79658334, rs121913021, rs62625308, rs80356898, rs80357579, rs41293497, rs80356904, rs80357471, rs80357522, rs80357234, rs80357912, rs80357828
View all (31 more)		 31043753
Show/Hide Text Mining Associations (4)
Associations from Text Mining
Disease Name Relationship Type References
Nasopharyngeal Carcinoma Associate 31863646
Ovarian Neoplasms Associate 31043753
Pregnancy Ectopic Associate 33771330
Pregnancy in Diabetics Associate 33771330