ERI1 (exoribonuclease 1)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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90459 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Exoribonuclease 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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ERI1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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3'HEXO, HEXO, HXAL, SEMDGC, SEMDGS, THEX1 |
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Chromosome
Chromosome number
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8 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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8p23.1 |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q8IV48 | |||||||||||||||
| Protein name | 3'-5' exoribonuclease 1 (EC 3.1.13.1) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO) | |||||||||||||||
| Protein function | RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication (PubMed:14536070, PubMed:16912046, PubMed:17135487, PubMed:37352860). A 2' and 3'-hyd | |||||||||||||||
| PDB | 1W0H , 1ZBH , 1ZBU , 4L8R , 4QOZ | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 349 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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