ERI1 (exoribonuclease 1)

Gene

• Entrez ID: 90459
• Gene name: Exoribonuclease 1
• Gene symbol: ERI1
• Synonyms (NCBI Gene): 3'HEXO, HEXO, HXAL, SEMDGC, SEMDGS, THEX1
• Chromosome: 8
• Chromosome location: 8p23.1

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs1563322318	A>-	Likely-pathogenic	Coding sequence variant, frameshift variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT020545	hsa-miR-155-5p	Proteomics	18668040
MIRT047993	hsa-miR-30c-5p	CLASH	23622248
MIRT650237	hsa-miR-20a-3p	HITS-CLIP	23824327
MIRT650236	hsa-miR-4724-3p	HITS-CLIP	23824327
MIRT650235	hsa-miR-544a	HITS-CLIP	23824327
MIRT650234	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT537634	hsa-miR-548ae-3p	PAR-CLIP	22012620
MIRT537633	hsa-miR-548ah-3p	PAR-CLIP	22012620
MIRT537632	hsa-miR-548aj-3p	PAR-CLIP	22012620
MIRT537631	hsa-miR-548am-3p	PAR-CLIP	22012620
MIRT537630	hsa-miR-548aq-3p	PAR-CLIP	22012620
MIRT537629	hsa-miR-548j-3p	PAR-CLIP	22012620
MIRT537628	hsa-miR-548x-3p	PAR-CLIP	22012620
MIRT537627	hsa-miR-3664-5p	PAR-CLIP	22012620
MIRT402602	hsa-miR-548p	PAR-CLIP	22012620
MIRT537626	hsa-miR-221-5p	PAR-CLIP	22012620
MIRT537625	hsa-miR-8073	PAR-CLIP	22012620
MIRT537624	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT537623	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT537622	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT537621	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT537620	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT537619	hsa-miR-6868-5p	PAR-CLIP	22012620
MIRT537618	hsa-miR-3120-5p	PAR-CLIP	22012620
MIRT537617	hsa-miR-6888-3p	PAR-CLIP	22012620
MIRT537616	hsa-miR-208a-3p	PAR-CLIP	22012620
MIRT447888	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT447886	hsa-miR-6507-5p	PAR-CLIP	22100165
MIRT447885	hsa-miR-1277-5p	PAR-CLIP	22100165
MIRT650237	hsa-miR-20a-3p	HITS-CLIP	23824327
MIRT650236	hsa-miR-4724-3p	HITS-CLIP	23824327
MIRT650235	hsa-miR-544a	HITS-CLIP	23824327
MIRT650234	hsa-miR-6738-3p	HITS-CLIP	23824327
MIRT537634	hsa-miR-548ae-3p	PAR-CLIP	22012620
MIRT537633	hsa-miR-548ah-3p	PAR-CLIP	22012620
MIRT537632	hsa-miR-548aj-3p	PAR-CLIP	22012620
MIRT537631	hsa-miR-548am-3p	PAR-CLIP	22012620
MIRT537630	hsa-miR-548aq-3p	PAR-CLIP	22012620
MIRT537629	hsa-miR-548j-3p	PAR-CLIP	22012620
MIRT537628	hsa-miR-548x-3p	PAR-CLIP	22012620
MIRT537627	hsa-miR-3664-5p	PAR-CLIP	22012620
MIRT402602	hsa-miR-548p	PAR-CLIP	22012620
MIRT537626	hsa-miR-221-5p	PAR-CLIP	22012620
MIRT537625	hsa-miR-8073	PAR-CLIP	22012620
MIRT537624	hsa-miR-371b-5p	PAR-CLIP	22012620
MIRT537623	hsa-miR-373-5p	PAR-CLIP	22012620
MIRT537622	hsa-miR-616-5p	PAR-CLIP	22012620
MIRT537621	hsa-miR-371a-5p	PAR-CLIP	22012620
MIRT537620	hsa-miR-372-5p	PAR-CLIP	22012620
MIRT537619	hsa-miR-6868-5p	PAR-CLIP	22012620
MIRT537618	hsa-miR-3120-5p	PAR-CLIP	22012620
MIRT537617	hsa-miR-6888-3p	PAR-CLIP	22012620
MIRT537616	hsa-miR-208a-3p	PAR-CLIP	22012620
MIRT447888	hsa-miR-186-5p	PAR-CLIP	22100165
MIRT447886	hsa-miR-6507-5p	PAR-CLIP	22100165
MIRT447885	hsa-miR-1277-5p	PAR-CLIP	22100165
MIRT969007	hsa-miR-106a	CLIP-seq
MIRT969008	hsa-miR-106b	CLIP-seq
MIRT969009	hsa-miR-1206	CLIP-seq
MIRT969010	hsa-miR-1263	CLIP-seq
MIRT969011	hsa-miR-142-5p	CLIP-seq
MIRT969012	hsa-miR-154	CLIP-seq
MIRT969013	hsa-miR-17	CLIP-seq
MIRT969014	hsa-miR-200b	CLIP-seq
MIRT969015	hsa-miR-200c	CLIP-seq
MIRT969016	hsa-miR-2054	CLIP-seq
MIRT969017	hsa-miR-20a	CLIP-seq
MIRT969018	hsa-miR-20b	CLIP-seq
MIRT969019	hsa-miR-21	CLIP-seq
MIRT969020	hsa-miR-2116	CLIP-seq
MIRT969021	hsa-miR-214	CLIP-seq
MIRT969022	hsa-miR-23a	CLIP-seq
MIRT969023	hsa-miR-23b	CLIP-seq
MIRT969024	hsa-miR-23c	CLIP-seq
MIRT969025	hsa-miR-298	CLIP-seq
MIRT969026	hsa-miR-302a	CLIP-seq
MIRT969027	hsa-miR-302b	CLIP-seq
MIRT969028	hsa-miR-302c	CLIP-seq
MIRT969029	hsa-miR-302d	CLIP-seq
MIRT969030	hsa-miR-302e	CLIP-seq
MIRT969031	hsa-miR-3074-5p	CLIP-seq
MIRT969032	hsa-miR-3125	CLIP-seq
MIRT969033	hsa-miR-3140-3p	CLIP-seq
MIRT969034	hsa-miR-3163	CLIP-seq
MIRT969035	hsa-miR-3200-5p	CLIP-seq
MIRT969036	hsa-miR-323-5p	CLIP-seq
MIRT969037	hsa-miR-340	CLIP-seq
MIRT969038	hsa-miR-34b	CLIP-seq
MIRT969039	hsa-miR-3609	CLIP-seq
MIRT969040	hsa-miR-3614-5p	CLIP-seq
MIRT969041	hsa-miR-3616-5p	CLIP-seq
MIRT969042	hsa-miR-3619-5p	CLIP-seq
MIRT969043	hsa-miR-3620	CLIP-seq
MIRT969044	hsa-miR-3622a-3p	CLIP-seq
MIRT969045	hsa-miR-3622b-3p	CLIP-seq
MIRT969046	hsa-miR-3647-5p	CLIP-seq
MIRT969047	hsa-miR-3656	CLIP-seq
MIRT969048	hsa-miR-3675-3p	CLIP-seq
MIRT969049	hsa-miR-3682-3p	CLIP-seq
MIRT969050	hsa-miR-369-3p	CLIP-seq
MIRT969051	hsa-miR-370	CLIP-seq
MIRT969052	hsa-miR-372	CLIP-seq
MIRT969053	hsa-miR-373	CLIP-seq
MIRT969054	hsa-miR-374a	CLIP-seq
MIRT969055	hsa-miR-374b	CLIP-seq
MIRT969056	hsa-miR-380	CLIP-seq
MIRT969057	hsa-miR-3916	CLIP-seq
MIRT969058	hsa-miR-409-3p	CLIP-seq
MIRT969059	hsa-miR-4263	CLIP-seq
MIRT969060	hsa-miR-4282	CLIP-seq
MIRT969061	hsa-miR-429	CLIP-seq
MIRT969062	hsa-miR-4291	CLIP-seq
MIRT969063	hsa-miR-4293	CLIP-seq
MIRT969064	hsa-miR-4433	CLIP-seq
MIRT969065	hsa-miR-4455	CLIP-seq
MIRT969066	hsa-miR-4459	CLIP-seq
MIRT969067	hsa-miR-4477a	CLIP-seq
MIRT969068	hsa-miR-4495	CLIP-seq
MIRT969069	hsa-miR-450b-3p	CLIP-seq
MIRT969070	hsa-miR-452	CLIP-seq
MIRT969071	hsa-miR-4666-5p	CLIP-seq
MIRT969072	hsa-miR-4670-3p	CLIP-seq
MIRT969073	hsa-miR-4676-3p	CLIP-seq
MIRT969074	hsa-miR-4719	CLIP-seq
MIRT969075	hsa-miR-4742-5p	CLIP-seq
MIRT969076	hsa-miR-4768-3p	CLIP-seq
MIRT969077	hsa-miR-4777-5p	CLIP-seq
MIRT969078	hsa-miR-4793-3p	CLIP-seq
MIRT969079	hsa-miR-4793-5p	CLIP-seq
MIRT969080	hsa-miR-495	CLIP-seq
MIRT969081	hsa-miR-5095	CLIP-seq
MIRT969082	hsa-miR-5096	CLIP-seq
MIRT969083	hsa-miR-512-3p	CLIP-seq
MIRT969084	hsa-miR-513a-3p	CLIP-seq
MIRT969085	hsa-miR-519d	CLIP-seq
MIRT969086	hsa-miR-520a-3p	CLIP-seq
MIRT969087	hsa-miR-520b	CLIP-seq
MIRT969088	hsa-miR-520c-3p	CLIP-seq
MIRT969089	hsa-miR-520d-3p	CLIP-seq
MIRT969090	hsa-miR-520e	CLIP-seq
MIRT969091	hsa-miR-548a-5p	CLIP-seq
MIRT969092	hsa-miR-548ab	CLIP-seq
MIRT969093	hsa-miR-548ah	CLIP-seq
MIRT969094	hsa-miR-548ak	CLIP-seq
MIRT969095	hsa-miR-548b-5p	CLIP-seq
MIRT969096	hsa-miR-548c-5p	CLIP-seq
MIRT969097	hsa-miR-548d-5p	CLIP-seq
MIRT969098	hsa-miR-548h	CLIP-seq
MIRT969099	hsa-miR-548i	CLIP-seq
MIRT969100	hsa-miR-548j	CLIP-seq
MIRT969101	hsa-miR-548k	CLIP-seq
MIRT969102	hsa-miR-548l	CLIP-seq
MIRT969103	hsa-miR-548n	CLIP-seq
MIRT969104	hsa-miR-548t	CLIP-seq
MIRT969105	hsa-miR-548w	CLIP-seq
MIRT969106	hsa-miR-548y	CLIP-seq
MIRT969107	hsa-miR-552	CLIP-seq
MIRT969108	hsa-miR-559	CLIP-seq
MIRT969109	hsa-miR-562	CLIP-seq
MIRT969110	hsa-miR-564	CLIP-seq
MIRT969111	hsa-miR-570	CLIP-seq
MIRT969112	hsa-miR-573	CLIP-seq
MIRT969113	hsa-miR-576-5p	CLIP-seq
MIRT969114	hsa-miR-577	CLIP-seq
MIRT969115	hsa-miR-583	CLIP-seq
MIRT969116	hsa-miR-590-5p	CLIP-seq
MIRT969117	hsa-miR-633	CLIP-seq
MIRT969118	hsa-miR-640	CLIP-seq
MIRT969119	hsa-miR-653	CLIP-seq
MIRT969120	hsa-miR-658	CLIP-seq
MIRT969121	hsa-miR-758	CLIP-seq
MIRT969122	hsa-miR-761	CLIP-seq
MIRT969123	hsa-miR-769-3p	CLIP-seq
MIRT969124	hsa-miR-873	CLIP-seq
MIRT969125	hsa-miR-876-3p	CLIP-seq
MIRT969126	hsa-miR-890	CLIP-seq
MIRT969127	hsa-miR-922	CLIP-seq
MIRT969128	hsa-miR-93	CLIP-seq
MIRT1987194	hsa-miR-1225-3p	CLIP-seq
MIRT1987195	hsa-miR-1233	CLIP-seq
MIRT1987196	hsa-miR-1238	CLIP-seq
MIRT1987197	hsa-miR-1271	CLIP-seq
MIRT1987198	hsa-miR-1294	CLIP-seq
MIRT1987199	hsa-miR-182	CLIP-seq
MIRT1987200	hsa-miR-1827	CLIP-seq
MIRT1987201	hsa-miR-196a	CLIP-seq
MIRT1987202	hsa-miR-196b	CLIP-seq
MIRT969014	hsa-miR-200b	CLIP-seq
MIRT969015	hsa-miR-200c	CLIP-seq
MIRT1987203	hsa-miR-203	CLIP-seq
MIRT1987204	hsa-miR-205	CLIP-seq
MIRT969044	hsa-miR-3622a-3p	CLIP-seq
MIRT969045	hsa-miR-3622b-3p	CLIP-seq
MIRT1987205	hsa-miR-3973	CLIP-seq
MIRT1987206	hsa-miR-4266	CLIP-seq
MIRT969061	hsa-miR-429	CLIP-seq
MIRT1987207	hsa-miR-4316	CLIP-seq
MIRT1987208	hsa-miR-4422	CLIP-seq
MIRT969066	hsa-miR-4459	CLIP-seq
MIRT1987209	hsa-miR-4635	CLIP-seq
MIRT1987210	hsa-miR-4677-3p	CLIP-seq
MIRT1987211	hsa-miR-4679	CLIP-seq
MIRT1987212	hsa-miR-4694-3p	CLIP-seq
MIRT1987213	hsa-miR-4695-5p	CLIP-seq
MIRT969074	hsa-miR-4719	CLIP-seq
MIRT1987214	hsa-miR-4736	CLIP-seq
MIRT1987215	hsa-miR-4759	CLIP-seq
MIRT1987216	hsa-miR-4779	CLIP-seq
MIRT1987217	hsa-miR-501-3p	CLIP-seq
MIRT1987218	hsa-miR-502-3p	CLIP-seq
MIRT1987219	hsa-miR-526b	CLIP-seq
MIRT969104	hsa-miR-548t	CLIP-seq
MIRT969114	hsa-miR-577	CLIP-seq
MIRT969118	hsa-miR-640	CLIP-seq
MIRT969120	hsa-miR-658	CLIP-seq
MIRT1987220	hsa-miR-665	CLIP-seq
MIRT1987221	hsa-miR-9	CLIP-seq
MIRT1987222	hsa-miR-940	CLIP-seq
MIRT1987223	hsa-miR-96	CLIP-seq
MIRT2221654	hsa-miR-1	CLIP-seq
MIRT1987196	hsa-miR-1238	CLIP-seq
MIRT2221655	hsa-miR-1245	CLIP-seq
MIRT2221656	hsa-miR-128	CLIP-seq
MIRT2221657	hsa-miR-151-5p	CLIP-seq
MIRT2221658	hsa-miR-151b	CLIP-seq
MIRT1987200	hsa-miR-1827	CLIP-seq
MIRT969014	hsa-miR-200b	CLIP-seq
MIRT969015	hsa-miR-200c	CLIP-seq
MIRT969016	hsa-miR-2054	CLIP-seq
MIRT2221659	hsa-miR-206	CLIP-seq
MIRT2221660	hsa-miR-224	CLIP-seq
MIRT2221661	hsa-miR-27a	CLIP-seq
MIRT2221662	hsa-miR-27b	CLIP-seq
MIRT2221663	hsa-miR-31	CLIP-seq
MIRT2221664	hsa-miR-3131	CLIP-seq
MIRT2221665	hsa-miR-3151	CLIP-seq
MIRT2221666	hsa-miR-3173-3p	CLIP-seq
MIRT2221667	hsa-miR-3188	CLIP-seq
MIRT2221668	hsa-miR-326	CLIP-seq
MIRT2221669	hsa-miR-330-5p	CLIP-seq
MIRT969038	hsa-miR-34b	CLIP-seq
MIRT969040	hsa-miR-3614-5p	CLIP-seq
MIRT969044	hsa-miR-3622a-3p	CLIP-seq
MIRT969045	hsa-miR-3622b-3p	CLIP-seq
MIRT2221670	hsa-miR-3658	CLIP-seq
MIRT2221671	hsa-miR-3663-5p	CLIP-seq
MIRT2221672	hsa-miR-3664-3p	CLIP-seq
MIRT2221673	hsa-miR-3673	CLIP-seq
MIRT969048	hsa-miR-3675-3p	CLIP-seq
MIRT2221674	hsa-miR-3929	CLIP-seq
MIRT2221675	hsa-miR-4265	CLIP-seq
MIRT969061	hsa-miR-429	CLIP-seq
MIRT969063	hsa-miR-4293	CLIP-seq
MIRT2221676	hsa-miR-4296	CLIP-seq
MIRT2221677	hsa-miR-4322	CLIP-seq
MIRT2221678	hsa-miR-4419b	CLIP-seq
MIRT969064	hsa-miR-4433	CLIP-seq
MIRT2221679	hsa-miR-4447	CLIP-seq
MIRT969066	hsa-miR-4459	CLIP-seq
MIRT2221680	hsa-miR-4472	CLIP-seq
MIRT2221681	hsa-miR-4478	CLIP-seq
MIRT2221682	hsa-miR-4649-3p	CLIP-seq
MIRT2221683	hsa-miR-4662a-3p	CLIP-seq
MIRT1987213	hsa-miR-4695-5p	CLIP-seq
MIRT969076	hsa-miR-4768-3p	CLIP-seq
MIRT969078	hsa-miR-4793-3p	CLIP-seq
MIRT2221684	hsa-miR-485-5p	CLIP-seq
MIRT2221685	hsa-miR-486-3p	CLIP-seq
MIRT2221686	hsa-miR-490-5p	CLIP-seq
MIRT2221687	hsa-miR-491-5p	CLIP-seq
MIRT2221688	hsa-miR-510	CLIP-seq
MIRT2221689	hsa-miR-512-5p	CLIP-seq
MIRT2221690	hsa-miR-515-5p	CLIP-seq
MIRT2221691	hsa-miR-516a-5p	CLIP-seq
MIRT2221692	hsa-miR-584	CLIP-seq
MIRT2221693	hsa-miR-593	CLIP-seq
MIRT2221694	hsa-miR-611	CLIP-seq
MIRT2221695	hsa-miR-613	CLIP-seq
MIRT969118	hsa-miR-640	CLIP-seq
MIRT969120	hsa-miR-658	CLIP-seq
MIRT1987204	hsa-miR-205	CLIP-seq
MIRT969044	hsa-miR-3622a-3p	CLIP-seq
MIRT969045	hsa-miR-3622b-3p	CLIP-seq
MIRT969066	hsa-miR-4459	CLIP-seq
MIRT1987213	hsa-miR-4695-5p	CLIP-seq
MIRT2448939	hsa-miR-3065-5p	CLIP-seq
MIRT2448940	hsa-miR-371-5p	CLIP-seq
MIRT2448941	hsa-miR-548ae	CLIP-seq
MIRT2448942	hsa-miR-548aj	CLIP-seq
MIRT2448943	hsa-miR-548am	CLIP-seq
MIRT2448944	hsa-miR-548x	CLIP-seq
MIRT1987194	hsa-miR-1225-3p	CLIP-seq
MIRT1987195	hsa-miR-1233	CLIP-seq
MIRT2525250	hsa-miR-124	CLIP-seq
MIRT1987197	hsa-miR-1271	CLIP-seq
MIRT2525251	hsa-miR-1283	CLIP-seq
MIRT1987198	hsa-miR-1294	CLIP-seq
MIRT2525252	hsa-miR-135a	CLIP-seq
MIRT2525253	hsa-miR-135b	CLIP-seq
MIRT2525254	hsa-miR-181a	CLIP-seq
MIRT2525255	hsa-miR-181b	CLIP-seq
MIRT2525256	hsa-miR-181c	CLIP-seq
MIRT2525257	hsa-miR-181d	CLIP-seq
MIRT1987199	hsa-miR-182	CLIP-seq
MIRT1987200	hsa-miR-1827	CLIP-seq
MIRT2525258	hsa-miR-186	CLIP-seq
MIRT2525259	hsa-miR-18a	CLIP-seq
MIRT2525260	hsa-miR-18b	CLIP-seq
MIRT2525261	hsa-miR-1914	CLIP-seq
MIRT1987201	hsa-miR-196a	CLIP-seq
MIRT1987202	hsa-miR-196b	CLIP-seq
MIRT969016	hsa-miR-2054	CLIP-seq
MIRT2525262	hsa-miR-208a	CLIP-seq
MIRT2525263	hsa-miR-208b	CLIP-seq
MIRT969019	hsa-miR-21	CLIP-seq
MIRT969020	hsa-miR-2116	CLIP-seq
MIRT969022	hsa-miR-23a	CLIP-seq
MIRT969023	hsa-miR-23b	CLIP-seq
MIRT969024	hsa-miR-23c	CLIP-seq
MIRT2525264	hsa-miR-24	CLIP-seq
MIRT2221663	hsa-miR-31	CLIP-seq
MIRT969032	hsa-miR-3125	CLIP-seq
MIRT2525265	hsa-miR-3137	CLIP-seq
MIRT2221665	hsa-miR-3151	CLIP-seq
MIRT2221666	hsa-miR-3173-3p	CLIP-seq
MIRT2221667	hsa-miR-3188	CLIP-seq
MIRT969035	hsa-miR-3200-5p	CLIP-seq
MIRT2525266	hsa-miR-339-3p	CLIP-seq
MIRT2525267	hsa-miR-33a	CLIP-seq
MIRT2525268	hsa-miR-33b	CLIP-seq
MIRT969038	hsa-miR-34b	CLIP-seq
MIRT969040	hsa-miR-3614-5p	CLIP-seq
MIRT969041	hsa-miR-3616-5p	CLIP-seq
MIRT2525269	hsa-miR-3617	CLIP-seq
MIRT969044	hsa-miR-3622a-3p	CLIP-seq
MIRT969045	hsa-miR-3622b-3p	CLIP-seq
MIRT969046	hsa-miR-3647-5p	CLIP-seq
MIRT2525270	hsa-miR-3662	CLIP-seq
MIRT2221672	hsa-miR-3664-3p	CLIP-seq
MIRT2525271	hsa-miR-3667-3p	CLIP-seq
MIRT969048	hsa-miR-3675-3p	CLIP-seq
MIRT2525272	hsa-miR-3685	CLIP-seq
MIRT2525273	hsa-miR-3714	CLIP-seq
MIRT2448940	hsa-miR-371-5p	CLIP-seq
MIRT969054	hsa-miR-374a	CLIP-seq
MIRT969055	hsa-miR-374b	CLIP-seq
MIRT2525274	hsa-miR-3910	CLIP-seq
MIRT969057	hsa-miR-3916	CLIP-seq
MIRT2525275	hsa-miR-3926	CLIP-seq
MIRT2221674	hsa-miR-3929	CLIP-seq
MIRT969058	hsa-miR-409-3p	CLIP-seq
MIRT2525276	hsa-miR-421	CLIP-seq
MIRT2525277	hsa-miR-4262	CLIP-seq
MIRT2221675	hsa-miR-4265	CLIP-seq
MIRT1987206	hsa-miR-4266	CLIP-seq
MIRT2525278	hsa-miR-4272	CLIP-seq
MIRT2525279	hsa-miR-4284	CLIP-seq
MIRT2221676	hsa-miR-4296	CLIP-seq
MIRT2525280	hsa-miR-4297	CLIP-seq
MIRT2525281	hsa-miR-4303	CLIP-seq
MIRT2525282	hsa-miR-4307	CLIP-seq
MIRT1987207	hsa-miR-4316	CLIP-seq
MIRT2221677	hsa-miR-4322	CLIP-seq
MIRT2525283	hsa-miR-4325	CLIP-seq
MIRT2221678	hsa-miR-4419b	CLIP-seq
MIRT969064	hsa-miR-4433	CLIP-seq
MIRT2221679	hsa-miR-4447	CLIP-seq
MIRT969066	hsa-miR-4459	CLIP-seq
MIRT2221680	hsa-miR-4472	CLIP-seq
MIRT2525284	hsa-miR-4477b	CLIP-seq
MIRT2221681	hsa-miR-4478	CLIP-seq
MIRT2525285	hsa-miR-4506	CLIP-seq
MIRT2525286	hsa-miR-450b-5p	CLIP-seq
MIRT2525287	hsa-miR-4633-5p	CLIP-seq
MIRT2525288	hsa-miR-4645-3p	CLIP-seq
MIRT2221682	hsa-miR-4649-3p	CLIP-seq
MIRT2525289	hsa-miR-4663	CLIP-seq
MIRT969071	hsa-miR-4666-5p	CLIP-seq
MIRT2525290	hsa-miR-4668-3p	CLIP-seq
MIRT969072	hsa-miR-4670-3p	CLIP-seq
MIRT1987210	hsa-miR-4677-3p	CLIP-seq
MIRT1987211	hsa-miR-4679	CLIP-seq
MIRT1987213	hsa-miR-4695-5p	CLIP-seq
MIRT2525291	hsa-miR-4700-3p	CLIP-seq
MIRT2525292	hsa-miR-4709-5p	CLIP-seq
MIRT2525293	hsa-miR-4720-3p	CLIP-seq
MIRT2525294	hsa-miR-4735-3p	CLIP-seq
MIRT1987214	hsa-miR-4736	CLIP-seq
MIRT1987215	hsa-miR-4759	CLIP-seq
MIRT2525295	hsa-miR-4761-5p	CLIP-seq
MIRT969076	hsa-miR-4768-3p	CLIP-seq
MIRT2525296	hsa-miR-4773	CLIP-seq
MIRT969077	hsa-miR-4777-5p	CLIP-seq
MIRT1987216	hsa-miR-4779	CLIP-seq
MIRT2525297	hsa-miR-4795-3p	CLIP-seq
MIRT2525298	hsa-miR-4804-3p	CLIP-seq
MIRT2221684	hsa-miR-485-5p	CLIP-seq
MIRT2221685	hsa-miR-486-3p	CLIP-seq
MIRT2221687	hsa-miR-491-5p	CLIP-seq
MIRT969080	hsa-miR-495	CLIP-seq
MIRT2525299	hsa-miR-499-5p	CLIP-seq
MIRT1987217	hsa-miR-501-3p	CLIP-seq
MIRT1987218	hsa-miR-502-3p	CLIP-seq
MIRT2525300	hsa-miR-506	CLIP-seq
MIRT2525301	hsa-miR-507	CLIP-seq
MIRT2221688	hsa-miR-510	CLIP-seq
MIRT2221689	hsa-miR-512-5p	CLIP-seq
MIRT2525302	hsa-miR-532-5p	CLIP-seq
MIRT2525303	hsa-miR-541	CLIP-seq
MIRT2525304	hsa-miR-548aa	CLIP-seq
MIRT2448941	hsa-miR-548ae	CLIP-seq
MIRT2448942	hsa-miR-548aj	CLIP-seq
MIRT2448943	hsa-miR-548am	CLIP-seq
MIRT2448944	hsa-miR-548x	CLIP-seq
MIRT2525305	hsa-miR-557	CLIP-seq
MIRT2525306	hsa-miR-561	CLIP-seq
MIRT969110	hsa-miR-564	CLIP-seq
MIRT969112	hsa-miR-573	CLIP-seq
MIRT2525307	hsa-miR-586	CLIP-seq
MIRT969116	hsa-miR-590-5p	CLIP-seq
MIRT2525308	hsa-miR-610	CLIP-seq
MIRT2525309	hsa-miR-641	CLIP-seq
MIRT969119	hsa-miR-653	CLIP-seq
MIRT2525310	hsa-miR-654-5p	CLIP-seq
MIRT969120	hsa-miR-658	CLIP-seq
MIRT1987220	hsa-miR-665	CLIP-seq
MIRT2525311	hsa-miR-671-5p	CLIP-seq
MIRT1987221	hsa-miR-9	CLIP-seq
MIRT1987222	hsa-miR-940	CLIP-seq
MIRT1987223	hsa-miR-96	CLIP-seq
MIRT1987194	hsa-miR-1225-3p	CLIP-seq
MIRT1987195	hsa-miR-1233	CLIP-seq
MIRT1987197	hsa-miR-1271	CLIP-seq
MIRT2525251	hsa-miR-1283	CLIP-seq
MIRT1987198	hsa-miR-1294	CLIP-seq
MIRT2525252	hsa-miR-135a	CLIP-seq
MIRT2525253	hsa-miR-135b	CLIP-seq
MIRT1987199	hsa-miR-182	CLIP-seq
MIRT1987200	hsa-miR-1827	CLIP-seq
MIRT2525258	hsa-miR-186	CLIP-seq
MIRT1987201	hsa-miR-196a	CLIP-seq
MIRT1987202	hsa-miR-196b	CLIP-seq
MIRT969016	hsa-miR-2054	CLIP-seq
MIRT2525262	hsa-miR-208a	CLIP-seq
MIRT2525263	hsa-miR-208b	CLIP-seq
MIRT969022	hsa-miR-23a	CLIP-seq
MIRT969023	hsa-miR-23b	CLIP-seq
MIRT969024	hsa-miR-23c	CLIP-seq
MIRT2221663	hsa-miR-31	CLIP-seq
MIRT969032	hsa-miR-3125	CLIP-seq
MIRT969035	hsa-miR-3200-5p	CLIP-seq
MIRT2525269	hsa-miR-3617	CLIP-seq
MIRT969044	hsa-miR-3622a-3p	CLIP-seq
MIRT969045	hsa-miR-3622b-3p	CLIP-seq
MIRT2525270	hsa-miR-3662	CLIP-seq
MIRT2221672	hsa-miR-3664-3p	CLIP-seq
MIRT2525271	hsa-miR-3667-3p	CLIP-seq
MIRT969048	hsa-miR-3675-3p	CLIP-seq
MIRT2525272	hsa-miR-3685	CLIP-seq
MIRT2448940	hsa-miR-371-5p	CLIP-seq
MIRT969057	hsa-miR-3916	CLIP-seq
MIRT2525275	hsa-miR-3926	CLIP-seq
MIRT2221674	hsa-miR-3929	CLIP-seq
MIRT2525276	hsa-miR-421	CLIP-seq
MIRT2525280	hsa-miR-4297	CLIP-seq
MIRT2525281	hsa-miR-4303	CLIP-seq
MIRT1987207	hsa-miR-4316	CLIP-seq
MIRT2221678	hsa-miR-4419b	CLIP-seq
MIRT969064	hsa-miR-4433	CLIP-seq
MIRT969066	hsa-miR-4459	CLIP-seq
MIRT2221681	hsa-miR-4478	CLIP-seq
MIRT2525285	hsa-miR-4506	CLIP-seq
MIRT2525287	hsa-miR-4633-5p	CLIP-seq
MIRT2525288	hsa-miR-4645-3p	CLIP-seq
MIRT2221682	hsa-miR-4649-3p	CLIP-seq
MIRT969071	hsa-miR-4666-5p	CLIP-seq
MIRT2525290	hsa-miR-4668-3p	CLIP-seq
MIRT1987210	hsa-miR-4677-3p	CLIP-seq
MIRT1987211	hsa-miR-4679	CLIP-seq
MIRT1987213	hsa-miR-4695-5p	CLIP-seq
MIRT2525292	hsa-miR-4709-5p	CLIP-seq
MIRT1987214	hsa-miR-4736	CLIP-seq
MIRT969076	hsa-miR-4768-3p	CLIP-seq
MIRT2221684	hsa-miR-485-5p	CLIP-seq
MIRT2525299	hsa-miR-499-5p	CLIP-seq
MIRT1987217	hsa-miR-501-3p	CLIP-seq
MIRT1987218	hsa-miR-502-3p	CLIP-seq
MIRT2221688	hsa-miR-510	CLIP-seq
MIRT2221689	hsa-miR-512-5p	CLIP-seq
MIRT2525302	hsa-miR-532-5p	CLIP-seq
MIRT2448941	hsa-miR-548ae	CLIP-seq
MIRT2448942	hsa-miR-548aj	CLIP-seq
MIRT2448943	hsa-miR-548am	CLIP-seq
MIRT2448944	hsa-miR-548x	CLIP-seq
MIRT969110	hsa-miR-564	CLIP-seq
MIRT2525307	hsa-miR-586	CLIP-seq
MIRT2525308	hsa-miR-610	CLIP-seq
MIRT2525309	hsa-miR-641	CLIP-seq
MIRT969120	hsa-miR-658	CLIP-seq
MIRT1987220	hsa-miR-665	CLIP-seq
MIRT1987221	hsa-miR-9	CLIP-seq
MIRT1987222	hsa-miR-940	CLIP-seq
MIRT1987223	hsa-miR-96	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000175	Function	3'-5'-RNA exonuclease activity	IBA
GO:0000175	Function	3'-5'-RNA exonuclease activity	IEA
GO:0000460	Process	Maturation of 5.8S rRNA	IMP	37352860
GO:0000467	Process	Exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	IEA
GO:0004518	Function	Nuclease activity	IEA
GO:0004527	Function	Exonuclease activity	IEA
GO:0005515	Function	Protein binding	IPI	23329046, 23804756
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA	16912046
GO:0005730	Component	Nucleolus	IEA
GO:0005730	Component	Nucleolus	ISS
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	16912046
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0006364	Process	RRNA processing	IEA
GO:0008408	Function	3'-5' exonuclease activity	IDA	14536070, 16912046
GO:0016787	Function	Hydrolase activity	IEA
GO:0019843	Function	RRNA binding	ISS
GO:0031047	Process	Regulatory ncRNA-mediated gene silencing	IEA
GO:0031125	Process	RRNA 3'-end processing	ISS
GO:0043022	Function	Ribosome binding	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0071044	Process	Histone mRNA catabolic process	IMP	18172165
GO:0071204	Component	Histone pre-mRNA 3'end processing complex	ISS
GO:0071207	Function	Histone pre-mRNA stem-loop binding	ISS

Other IDs

• MIM: 608739
• HGNC: 23994
• e!Ensembl: ENSG00000104626

Protein

• UniProt ID: Q8IV48
• Protein name: 3'-5' exoribonuclease 1 (EC 3.1.13.1) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO)
• Protein function: RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication (PubMed:14536070, PubMed:16912046, PubMed:17135487, PubMed:37352860). A 2' and 3'-hyd
• PDB: 1W0H, 1ZBH, 1ZBU, 4L8R, 4QOZ
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF02037	SAP	76 → 110	SAP domain	Family
  PF00929	RNase_T	131 → 306	Exonuclease	Family

• Sequence:

  MEDPQSKEPAGEAVALALLESPRPEGGEEPPRPSPEETQQCKFDGQETKGSKFITSSASD
  FSDPVYKEIAITNGCINRMSKEELRAKLSEFKLETRGVKDVLKKRLKNYYKKQKLMLKES
  NFADSYYDYICIIDFEATCEEGNPPEFVHEIIEFPVVLLNTHTLEIEDTFQQYVRPEINT
  QLSDFCISLTGITQDQVDRADTFPQVLKKVIDWMKLKELGTKYKYSLLTDGSWDMSKFLN
  IQCQLSRLKYPPFAKKWINIRKSYGNFYKVPRSQTKLTIMLEKLGMDYDGRPHCGLDDSK
  NIARIAVRMLQDGCELRINEKMHAGQLMSVSSSLPIEGTPPPQMPHFRK

• Sequence length: 349

Pathways

Reactome:

Major pathway of rRNA processing in the nucleolus and cytosol

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Abnormal finger morphology	Likely pathogenic	rs1563322318	RCV000714292
Coarse facial features	Likely pathogenic	rs1563322318	RCV000714292
ERI1-associated disorder	Likely pathogenic	rs766625084	RCV001254154
Global developmental delay	Likely pathogenic	rs1563322318	RCV000714292
Hoxha-Aliu syndrome	Likely pathogenic; Pathogenic	rs2486218891, rs1221141256, rs2486243611, rs766625084	RCV003459873 RCV003459879 RCV003985062 RCV003462836
See cases	Likely pathogenic	rs2486219481, rs2486309230	RCV002331857 RCV002331858
Spondyloepimetaphyseal dysplasia, Guo-Campeau type	Likely pathogenic; Pathogenic	rs2486219481, rs2486309230, rs2486219940, rs1433280953, rs982911729, rs2486175152	RCV003464411 RCV003464412 RCV003459874 RCV003459875 RCV003459876 RCV003459877 RCV003459878
Unilateral renal agenesis	Likely pathogenic	rs1563322318	RCV000714292

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Acute myeloid leukemia	Likely benign	rs201166261	RCV005904406
ERI1-related disorder	Uncertain significance; Likely benign; Benign	rs774749825, rs763027684, rs113245883, rs143220656, rs556702690, rs2288672, rs61736769, rs139484248, rs9650616, rs747593226, rs150186258, rs201166261	RCV003406243 RCV003907194 RCV003904231 RCV003903898 RCV003916886 RCV003977340 RCV003972065 RCV003941670 RCV003958955 RCV003969259 RCV003946967 RCV003977025 RCV003981970 RCV003930626

Associations from Text Mining
Disease Name	Relationship Type	References
Infections	Associate	32960265
Spondyloepimetaphyseal Dysplasia X Linked	Associate	37352860