ERI1 (exoribonuclease 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
90459 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
Exoribonuclease 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
ERI1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
3'HEXO, HEXO, HXAL, SEMDGC, SEMDGS, THEX1 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
|
HXAL, SEMDGC |
Chromosome
Chromosome number
|
8 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
8p23.1 |
SNPs
SNP information provided by dbSNP.
|
|||||||||
|
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | ||||||||||||||||
UniProt ID | Q8IV48 | |||||||||||||||
Protein name | 3'-5' exoribonuclease 1 (EC 3.1.13.1) (3'-5' exonuclease ERI1) (Eri-1 homolog) (Histone mRNA 3'-end-specific exoribonuclease) (Histone mRNA 3'-exonuclease 1) (Protein 3'hExo) (HEXO) | |||||||||||||||
Protein function | RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication (PubMed:14536070, PubMed:16912046, PubMed:17135487, PubMed:37352860). A 2' and 3'-hyd | |||||||||||||||
PDB | 1W0H , 1ZBH , 1ZBU , 4L8R , 4QOZ | |||||||||||||||
Family and domains |
Pfam
|
|||||||||||||||
Sequence |
|
|||||||||||||||
Sequence length | 349 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||
|
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|