THAP3 (THAP domain containing 3)

Gene

• Entrez ID: 90326
• Gene name: THAP domain containing 3
• Gene symbol: THAP3
• Synonyms (NCBI Gene): -
• Chromosome: 1
• Chromosome location: 1p36.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT017413	hsa-miR-335-5p	Microarray	18185580
MIRT029166	hsa-miR-26b-5p	Microarray	19088304
MIRT045903	hsa-miR-125b-5p	CLASH	23622248
MIRT1422435	hsa-miR-1184	CLIP-seq
MIRT1422436	hsa-miR-1224-3p	CLIP-seq
MIRT1422437	hsa-miR-1254	CLIP-seq
MIRT1422438	hsa-miR-1263	CLIP-seq
MIRT1422439	hsa-miR-1285	CLIP-seq
MIRT1422440	hsa-miR-1538	CLIP-seq
MIRT1422441	hsa-miR-1912	CLIP-seq
MIRT1422442	hsa-miR-214	CLIP-seq
MIRT1422443	hsa-miR-2861	CLIP-seq
MIRT1422444	hsa-miR-3116	CLIP-seq
MIRT1422445	hsa-miR-3130-5p	CLIP-seq
MIRT1422446	hsa-miR-3136-3p	CLIP-seq
MIRT1422447	hsa-miR-3166	CLIP-seq
MIRT1422448	hsa-miR-3179	CLIP-seq
MIRT1422449	hsa-miR-3187-5p	CLIP-seq
MIRT1422450	hsa-miR-3611	CLIP-seq
MIRT1422451	hsa-miR-3619-5p	CLIP-seq
MIRT1422452	hsa-miR-3620	CLIP-seq
MIRT1422453	hsa-miR-3663-3p	CLIP-seq
MIRT1422454	hsa-miR-3665	CLIP-seq
MIRT1422455	hsa-miR-3689d	CLIP-seq
MIRT1422456	hsa-miR-4275	CLIP-seq
MIRT1422457	hsa-miR-4418	CLIP-seq
MIRT1422458	hsa-miR-4475	CLIP-seq
MIRT1422459	hsa-miR-4482	CLIP-seq
MIRT1422460	hsa-miR-4484	CLIP-seq
MIRT1422461	hsa-miR-4494	CLIP-seq
MIRT1422462	hsa-miR-4501	CLIP-seq
MIRT1422463	hsa-miR-4530	CLIP-seq
MIRT1422464	hsa-miR-4641	CLIP-seq
MIRT1422465	hsa-miR-4731-5p	CLIP-seq
MIRT1422466	hsa-miR-4745-3p	CLIP-seq
MIRT1422467	hsa-miR-4747-3p	CLIP-seq
MIRT1422468	hsa-miR-4771	CLIP-seq
MIRT1422469	hsa-miR-4795-5p	CLIP-seq
MIRT1422470	hsa-miR-4800-5p	CLIP-seq
MIRT1422471	hsa-miR-509-3-5p	CLIP-seq
MIRT1422472	hsa-miR-509-5p	CLIP-seq
MIRT1422473	hsa-miR-512-3p	CLIP-seq
MIRT1422474	hsa-miR-520a-5p	CLIP-seq
MIRT1422475	hsa-miR-525-5p	CLIP-seq
MIRT1422476	hsa-miR-612	CLIP-seq
MIRT1422477	hsa-miR-711	CLIP-seq
MIRT1422478	hsa-miR-759	CLIP-seq
MIRT1422479	hsa-miR-761	CLIP-seq
MIRT1422480	hsa-miR-885-3p	CLIP-seq
MIRT2126762	hsa-miR-1205	CLIP-seq
MIRT2126763	hsa-miR-1827	CLIP-seq
MIRT2126764	hsa-miR-1976	CLIP-seq
MIRT2126765	hsa-miR-3117-3p	CLIP-seq
MIRT2126766	hsa-miR-3169	CLIP-seq
MIRT1422454	hsa-miR-3665	CLIP-seq
MIRT2126767	hsa-miR-3690	CLIP-seq
MIRT2126768	hsa-miR-4649-3p	CLIP-seq
MIRT2126769	hsa-miR-4690-3p	CLIP-seq
MIRT2126770	hsa-miR-4738-5p	CLIP-seq
MIRT2126771	hsa-miR-4740-5p	CLIP-seq
MIRT2126772	hsa-miR-4759	CLIP-seq
MIRT2126773	hsa-miR-657	CLIP-seq
MIRT2126774	hsa-miR-766	CLIP-seq
MIRT2348550	hsa-miR-124	CLIP-seq
MIRT2348551	hsa-miR-1470	CLIP-seq
MIRT2348552	hsa-miR-197	CLIP-seq
MIRT2348553	hsa-miR-1972	CLIP-seq
MIRT2348554	hsa-miR-4469	CLIP-seq
MIRT2348555	hsa-miR-4514	CLIP-seq
MIRT2348556	hsa-miR-4650-5p	CLIP-seq
MIRT2348557	hsa-miR-4667-3p	CLIP-seq
MIRT2348558	hsa-miR-4690-5p	CLIP-seq
MIRT2348559	hsa-miR-4692	CLIP-seq
MIRT2348560	hsa-miR-4774-5p	CLIP-seq
MIRT2348561	hsa-miR-4783-3p	CLIP-seq
MIRT2348562	hsa-miR-506	CLIP-seq
MIRT2348563	hsa-miR-940	CLIP-seq
MIRT2395781	hsa-miR-579	CLIP-seq
MIRT1422435	hsa-miR-1184	CLIP-seq
MIRT2461406	hsa-miR-1207-3p	CLIP-seq
MIRT1422436	hsa-miR-1224-3p	CLIP-seq
MIRT2461407	hsa-miR-1226	CLIP-seq
MIRT1422439	hsa-miR-1285	CLIP-seq
MIRT2348551	hsa-miR-1470	CLIP-seq
MIRT2348553	hsa-miR-1972	CLIP-seq
MIRT2461408	hsa-miR-2277-5p	CLIP-seq
MIRT2461409	hsa-miR-2355-5p	CLIP-seq
MIRT2461410	hsa-miR-296-5p	CLIP-seq
MIRT2461411	hsa-miR-3130-3p	CLIP-seq
MIRT1422446	hsa-miR-3136-3p	CLIP-seq
MIRT2461412	hsa-miR-3153	CLIP-seq
MIRT2461413	hsa-miR-3160-3p	CLIP-seq
MIRT2461414	hsa-miR-3173-5p	CLIP-seq
MIRT2461415	hsa-miR-3176	CLIP-seq
MIRT1422449	hsa-miR-3187-5p	CLIP-seq
MIRT2461416	hsa-miR-3195	CLIP-seq
MIRT2461417	hsa-miR-3657	CLIP-seq
MIRT2461418	hsa-miR-3922-3p	CLIP-seq
MIRT2461419	hsa-miR-4329	CLIP-seq
MIRT1422457	hsa-miR-4418	CLIP-seq
MIRT2461420	hsa-miR-4436b-3p	CLIP-seq
MIRT2461421	hsa-miR-4449	CLIP-seq
MIRT2348554	hsa-miR-4469	CLIP-seq
MIRT2461422	hsa-miR-4487	CLIP-seq
MIRT1422461	hsa-miR-4494	CLIP-seq
MIRT2461423	hsa-miR-4634	CLIP-seq
MIRT1422464	hsa-miR-4641	CLIP-seq
MIRT2348556	hsa-miR-4650-5p	CLIP-seq
MIRT2461424	hsa-miR-4660	CLIP-seq
MIRT2348557	hsa-miR-4667-3p	CLIP-seq
MIRT2461425	hsa-miR-4668-5p	CLIP-seq
MIRT2461426	hsa-miR-4669	CLIP-seq
MIRT2126769	hsa-miR-4690-3p	CLIP-seq
MIRT2461427	hsa-miR-4715-3p	CLIP-seq
MIRT2461428	hsa-miR-4722-3p	CLIP-seq
MIRT1422465	hsa-miR-4731-5p	CLIP-seq
MIRT2461429	hsa-miR-4740-3p	CLIP-seq
MIRT2348560	hsa-miR-4774-5p	CLIP-seq
MIRT2348561	hsa-miR-4783-3p	CLIP-seq
MIRT1422471	hsa-miR-509-3-5p	CLIP-seq
MIRT1422472	hsa-miR-509-5p	CLIP-seq
MIRT1422473	hsa-miR-512-3p	CLIP-seq
MIRT1422474	hsa-miR-520a-5p	CLIP-seq
MIRT1422475	hsa-miR-525-5p	CLIP-seq
MIRT2461430	hsa-miR-552	CLIP-seq
MIRT2461431	hsa-miR-558	CLIP-seq
MIRT1422476	hsa-miR-612	CLIP-seq
MIRT2461432	hsa-miR-628-5p	CLIP-seq
MIRT2461433	hsa-miR-642b	CLIP-seq
MIRT1422478	hsa-miR-759	CLIP-seq
MIRT2126774	hsa-miR-766	CLIP-seq
MIRT2461434	hsa-miR-767-5p	CLIP-seq
MIRT1422435	hsa-miR-1184	CLIP-seq
MIRT2461406	hsa-miR-1207-3p	CLIP-seq
MIRT2461407	hsa-miR-1226	CLIP-seq
MIRT2466216	hsa-miR-1292	CLIP-seq
MIRT2348551	hsa-miR-1470	CLIP-seq
MIRT2126763	hsa-miR-1827	CLIP-seq
MIRT2461408	hsa-miR-2277-5p	CLIP-seq
MIRT2461410	hsa-miR-296-5p	CLIP-seq
MIRT2461411	hsa-miR-3130-3p	CLIP-seq
MIRT2461413	hsa-miR-3160-3p	CLIP-seq
MIRT2461415	hsa-miR-3176	CLIP-seq
MIRT2461416	hsa-miR-3195	CLIP-seq
MIRT2461417	hsa-miR-3657	CLIP-seq
MIRT2461418	hsa-miR-3922-3p	CLIP-seq
MIRT2466217	hsa-miR-4286	CLIP-seq
MIRT2466218	hsa-miR-4323	CLIP-seq
MIRT1422457	hsa-miR-4418	CLIP-seq
MIRT2466219	hsa-miR-4471	CLIP-seq
MIRT2461422	hsa-miR-4487	CLIP-seq
MIRT1422461	hsa-miR-4494	CLIP-seq
MIRT2461423	hsa-miR-4634	CLIP-seq
MIRT2466220	hsa-miR-4646-5p	CLIP-seq
MIRT2348557	hsa-miR-4667-3p	CLIP-seq
MIRT2461426	hsa-miR-4669	CLIP-seq
MIRT2461427	hsa-miR-4715-3p	CLIP-seq
MIRT2466221	hsa-miR-4758-3p	CLIP-seq
MIRT1422471	hsa-miR-509-3-5p	CLIP-seq
MIRT1422472	hsa-miR-509-5p	CLIP-seq
MIRT2461430	hsa-miR-552	CLIP-seq
MIRT2461431	hsa-miR-558	CLIP-seq
MIRT2461432	hsa-miR-628-5p	CLIP-seq
MIRT2126774	hsa-miR-766	CLIP-seq
MIRT1422435	hsa-miR-1184	CLIP-seq
MIRT2641595	hsa-miR-1203	CLIP-seq
MIRT2461406	hsa-miR-1207-3p	CLIP-seq
MIRT1422436	hsa-miR-1224-3p	CLIP-seq
MIRT2461407	hsa-miR-1226	CLIP-seq
MIRT1422439	hsa-miR-1285	CLIP-seq
MIRT2466216	hsa-miR-1292	CLIP-seq
MIRT2641596	hsa-miR-1343	CLIP-seq
MIRT2641597	hsa-miR-146b-3p	CLIP-seq
MIRT2348551	hsa-miR-1470	CLIP-seq
MIRT2126763	hsa-miR-1827	CLIP-seq
MIRT2641598	hsa-miR-1914	CLIP-seq
MIRT2641599	hsa-miR-193a-5p	CLIP-seq
MIRT2348553	hsa-miR-1972	CLIP-seq
MIRT2641600	hsa-miR-205	CLIP-seq
MIRT2461408	hsa-miR-2277-5p	CLIP-seq
MIRT2461409	hsa-miR-2355-5p	CLIP-seq
MIRT2461410	hsa-miR-296-5p	CLIP-seq
MIRT2461411	hsa-miR-3130-3p	CLIP-seq
MIRT1422446	hsa-miR-3136-3p	CLIP-seq
MIRT2461412	hsa-miR-3153	CLIP-seq
MIRT2461413	hsa-miR-3160-3p	CLIP-seq
MIRT2641601	hsa-miR-3168	CLIP-seq
MIRT2461414	hsa-miR-3173-5p	CLIP-seq
MIRT2461415	hsa-miR-3176	CLIP-seq
MIRT1422449	hsa-miR-3187-5p	CLIP-seq
MIRT2461416	hsa-miR-3195	CLIP-seq
MIRT2641602	hsa-miR-3200-5p	CLIP-seq
MIRT2641603	hsa-miR-335	CLIP-seq
MIRT2641604	hsa-miR-3614-3p	CLIP-seq
MIRT2641605	hsa-miR-3652	CLIP-seq
MIRT2461417	hsa-miR-3657	CLIP-seq
MIRT2641606	hsa-miR-3667-3p	CLIP-seq
MIRT1422455	hsa-miR-3689d	CLIP-seq
MIRT2126767	hsa-miR-3690	CLIP-seq
MIRT2461418	hsa-miR-3922-3p	CLIP-seq
MIRT2641607	hsa-miR-4254	CLIP-seq
MIRT2641608	hsa-miR-4277	CLIP-seq
MIRT2466217	hsa-miR-4286	CLIP-seq
MIRT2641609	hsa-miR-4297	CLIP-seq
MIRT2466218	hsa-miR-4323	CLIP-seq
MIRT2461419	hsa-miR-4329	CLIP-seq
MIRT1422457	hsa-miR-4418	CLIP-seq
MIRT2641610	hsa-miR-4430	CLIP-seq
MIRT2461420	hsa-miR-4436b-3p	CLIP-seq
MIRT2641611	hsa-miR-4446-5p	CLIP-seq
MIRT2461421	hsa-miR-4449	CLIP-seq
MIRT2348554	hsa-miR-4469	CLIP-seq
MIRT2466219	hsa-miR-4471	CLIP-seq
MIRT2461422	hsa-miR-4487	CLIP-seq
MIRT1422461	hsa-miR-4494	CLIP-seq
MIRT2641612	hsa-miR-4505	CLIP-seq
MIRT2641613	hsa-miR-4632	CLIP-seq
MIRT2461423	hsa-miR-4634	CLIP-seq
MIRT1422464	hsa-miR-4641	CLIP-seq
MIRT2466220	hsa-miR-4646-5p	CLIP-seq
MIRT2348556	hsa-miR-4650-5p	CLIP-seq
MIRT2461424	hsa-miR-4660	CLIP-seq
MIRT2348557	hsa-miR-4667-3p	CLIP-seq
MIRT2461425	hsa-miR-4668-5p	CLIP-seq
MIRT2461426	hsa-miR-4669	CLIP-seq
MIRT2641614	hsa-miR-4682	CLIP-seq
MIRT2641615	hsa-miR-4687-3p	CLIP-seq
MIRT2126769	hsa-miR-4690-3p	CLIP-seq
MIRT2641616	hsa-miR-4700-3p	CLIP-seq
MIRT2641617	hsa-miR-4703-3p	CLIP-seq
MIRT2641618	hsa-miR-4707-3p	CLIP-seq
MIRT2461427	hsa-miR-4715-3p	CLIP-seq
MIRT2461428	hsa-miR-4722-3p	CLIP-seq
MIRT1422465	hsa-miR-4731-5p	CLIP-seq
MIRT2461429	hsa-miR-4740-3p	CLIP-seq
MIRT2641619	hsa-miR-4747-5p	CLIP-seq
MIRT2466221	hsa-miR-4758-3p	CLIP-seq
MIRT2348560	hsa-miR-4774-5p	CLIP-seq
MIRT2348561	hsa-miR-4783-3p	CLIP-seq
MIRT1422471	hsa-miR-509-3-5p	CLIP-seq
MIRT1422472	hsa-miR-509-5p	CLIP-seq
MIRT1422473	hsa-miR-512-3p	CLIP-seq
MIRT2641620	hsa-miR-516b	CLIP-seq
MIRT1422474	hsa-miR-520a-5p	CLIP-seq
MIRT1422475	hsa-miR-525-5p	CLIP-seq
MIRT2461430	hsa-miR-552	CLIP-seq
MIRT2461431	hsa-miR-558	CLIP-seq
MIRT1422476	hsa-miR-612	CLIP-seq
MIRT2461432	hsa-miR-628-5p	CLIP-seq
MIRT2461433	hsa-miR-642b	CLIP-seq
MIRT2641621	hsa-miR-647	CLIP-seq
MIRT1422478	hsa-miR-759	CLIP-seq
MIRT2126774	hsa-miR-766	CLIP-seq
MIRT2461434	hsa-miR-767-5p	CLIP-seq
MIRT1422435	hsa-miR-1184	CLIP-seq
MIRT2641595	hsa-miR-1203	CLIP-seq
MIRT2461406	hsa-miR-1207-3p	CLIP-seq
MIRT1422436	hsa-miR-1224-3p	CLIP-seq
MIRT2461407	hsa-miR-1226	CLIP-seq
MIRT1422439	hsa-miR-1285	CLIP-seq
MIRT2466216	hsa-miR-1292	CLIP-seq
MIRT2641596	hsa-miR-1343	CLIP-seq
MIRT2641597	hsa-miR-146b-3p	CLIP-seq
MIRT2348551	hsa-miR-1470	CLIP-seq
MIRT2126763	hsa-miR-1827	CLIP-seq
MIRT2641598	hsa-miR-1914	CLIP-seq
MIRT2348553	hsa-miR-1972	CLIP-seq
MIRT2641600	hsa-miR-205	CLIP-seq
MIRT2461408	hsa-miR-2277-5p	CLIP-seq
MIRT2461410	hsa-miR-296-5p	CLIP-seq
MIRT2461411	hsa-miR-3130-3p	CLIP-seq
MIRT1422446	hsa-miR-3136-3p	CLIP-seq
MIRT2461412	hsa-miR-3153	CLIP-seq
MIRT2461413	hsa-miR-3160-3p	CLIP-seq
MIRT2641601	hsa-miR-3168	CLIP-seq
MIRT2461414	hsa-miR-3173-5p	CLIP-seq
MIRT2461415	hsa-miR-3176	CLIP-seq
MIRT1422449	hsa-miR-3187-5p	CLIP-seq
MIRT2461416	hsa-miR-3195	CLIP-seq
MIRT2693107	hsa-miR-3202	CLIP-seq
MIRT2641603	hsa-miR-335	CLIP-seq
MIRT2641604	hsa-miR-3614-3p	CLIP-seq
MIRT2461417	hsa-miR-3657	CLIP-seq
MIRT2641606	hsa-miR-3667-3p	CLIP-seq
MIRT2126767	hsa-miR-3690	CLIP-seq
MIRT2461418	hsa-miR-3922-3p	CLIP-seq
MIRT2641607	hsa-miR-4254	CLIP-seq
MIRT2641608	hsa-miR-4277	CLIP-seq
MIRT2466217	hsa-miR-4286	CLIP-seq
MIRT2641609	hsa-miR-4297	CLIP-seq
MIRT2466218	hsa-miR-4323	CLIP-seq
MIRT2461419	hsa-miR-4329	CLIP-seq
MIRT1422457	hsa-miR-4418	CLIP-seq
MIRT2461420	hsa-miR-4436b-3p	CLIP-seq
MIRT2641611	hsa-miR-4446-5p	CLIP-seq
MIRT2461421	hsa-miR-4449	CLIP-seq
MIRT2348554	hsa-miR-4469	CLIP-seq
MIRT2466219	hsa-miR-4471	CLIP-seq
MIRT2461422	hsa-miR-4487	CLIP-seq
MIRT1422461	hsa-miR-4494	CLIP-seq
MIRT2641613	hsa-miR-4632	CLIP-seq
MIRT2461423	hsa-miR-4634	CLIP-seq
MIRT1422464	hsa-miR-4641	CLIP-seq
MIRT2466220	hsa-miR-4646-5p	CLIP-seq
MIRT2348556	hsa-miR-4650-5p	CLIP-seq
MIRT2461424	hsa-miR-4660	CLIP-seq
MIRT2348557	hsa-miR-4667-3p	CLIP-seq
MIRT2461425	hsa-miR-4668-5p	CLIP-seq
MIRT2461426	hsa-miR-4669	CLIP-seq
MIRT2641615	hsa-miR-4687-3p	CLIP-seq
MIRT2126769	hsa-miR-4690-3p	CLIP-seq
MIRT2641616	hsa-miR-4700-3p	CLIP-seq
MIRT2641617	hsa-miR-4703-3p	CLIP-seq
MIRT2641618	hsa-miR-4707-3p	CLIP-seq
MIRT2461427	hsa-miR-4715-3p	CLIP-seq
MIRT2461428	hsa-miR-4722-3p	CLIP-seq
MIRT1422465	hsa-miR-4731-5p	CLIP-seq
MIRT2461429	hsa-miR-4740-3p	CLIP-seq
MIRT2641619	hsa-miR-4747-5p	CLIP-seq
MIRT2466221	hsa-miR-4758-3p	CLIP-seq
MIRT2348561	hsa-miR-4783-3p	CLIP-seq
MIRT1422471	hsa-miR-509-3-5p	CLIP-seq
MIRT1422472	hsa-miR-509-5p	CLIP-seq
MIRT1422473	hsa-miR-512-3p	CLIP-seq
MIRT1422474	hsa-miR-520a-5p	CLIP-seq
MIRT1422475	hsa-miR-525-5p	CLIP-seq
MIRT2461430	hsa-miR-552	CLIP-seq
MIRT2461431	hsa-miR-558	CLIP-seq
MIRT1422476	hsa-miR-612	CLIP-seq
MIRT2461432	hsa-miR-628-5p	CLIP-seq
MIRT2461433	hsa-miR-642b	CLIP-seq
MIRT1422478	hsa-miR-759	CLIP-seq
MIRT2126774	hsa-miR-766	CLIP-seq
MIRT2461434	hsa-miR-767-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	20200153, 32296183, 32814053, 33961781, 34819669
GO:0008270	Function	Zinc ion binding	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	20200153
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 612532
• HGNC: 20855
• e!Ensembl: ENSG00000041988

Protein

• UniProt ID: Q8WTV1
• Protein name: THAP domain-containing protein 3
• Protein function: Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF05485	THAP	5 → 82	THAP domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in heart, skeletal muscle and placenta. Weaker expression in brain, kidney and liver. {ECO:0000269|PubMed:20200153}.
• Sequence:

  MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLKEWVLNIGRGNFKPKQHTVICSEHFR
  PECFSAFGNRKNLKHNAVPTVFAFQDPTQQVRENTDPASERGNASSSQKEKVLPEAGAGE
  DSPGRNMDTALEELQLPPNAEGHVKQVSPRRPQATEAVGRPTGPAGLRRTPNKQPSDHSY
  ALLDLDSLKKKLFLTLKENEKLRKRLQAQRLVMRRMSSRLRACKGHQGLQARLGPEQQS

• Sequence length: 239