Gene Gene information from NCBI Gene database.
Entrez ID 9019
Gene name Myelin protein zero like 1
Gene symbol MPZL1
Synonyms (NCBI Gene)
MPZL1bPZRPZR1bPZRaPZRb
Chromosome 1
Chromosome location 1q24.2
miRNA miRNA information provided by mirtarbase database.
690
miRTarBase ID miRNA Experiments Reference
MIRT001534 hsa-miR-155-5p pSILAC 18668040
MIRT001534 hsa-miR-155-5p Proteomics;Other 18668040
MIRT024733 hsa-miR-215-5p Microarray 19074876
MIRT026720 hsa-miR-192-5p Microarray 19074876
MIRT039008 hsa-miR-766-3p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
GO ID Ontology Definition Evidence Reference
GO:0005198 Function Structural molecule activity TAS 9792637
GO:0005515 Function Protein binding IPI 9792637, 10681522, 32296183, 33961781
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane TAS 9792637
GO:0005925 Component Focal adhesion HDA 21423176
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604376 7226 ENSG00000197965
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O95297
Protein name Myelin protein zero-like protein 1 (Protein zero-related)
Protein function Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signalin
PDB 6IGO , 6IGT , 6IGW
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 41 155 Immunoglobulin V-set domain Domain
Tissue specificity TISSUE SPECIFICITY: Widely expressed with highest levels in heart, placenta, kidney and pancreas. Isoform 3 is relatively abundant in hematopoietic tissues and fetal liver. Isoform 1 and isoform 3 are expressed in CD14- PB monocytes and pre-B cell progeni
Sequence
MAASAGAGAVIAAPDSRRWLWSVLAAALGLLTAGVSALEVYTPKEIFVANGTQGKLTCKF
KSTSTTGGLTSVSWSFQPEGADTTVSFFHYSQGQVYLGNYPPFKDRISWAGDLDKKDASI
NIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYVV
EKENLPVFPVWVVVGIVTAVVLGLT
LLISMILAVLYRRKNSKRDYTGCSTSESLSPVKQAPRKSPSDTEGLVKSLPSGSHQGPVI
YAQLDHSGGHHSDKINKSESVVYADIRKN
Sequence length 269
Interactions View interactions