Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID	89953
Gene name	Kinesin light chain 4
Gene symbol	KLC4
Synonyms (NCBI Gene)	CONDRHNKNSL8bA387M24.3
Chromosome	6
Chromosome location	6p21.1

115

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miRTarBase ID	miRNA	Experiments	Reference
MIRT018861	hsa-miR-335-5p	Microarray	18185580
MIRT035911	hsa-miR-1180-3p	CLASH	23622248
MIRT1095681	hsa-miR-15a	CLIP-seq
MIRT1095682	hsa-miR-15b	CLIP-seq
MIRT1095683	hsa-miR-16	CLIP-seq
MIRT1095684	hsa-miR-195	CLIP-seq
MIRT1095685	hsa-miR-214	CLIP-seq
MIRT1095686	hsa-miR-3182	CLIP-seq
MIRT1095687	hsa-miR-3616-3p	CLIP-seq
MIRT1095688	hsa-miR-3619-5p	CLIP-seq
MIRT1095689	hsa-miR-3921	CLIP-seq
MIRT1095690	hsa-miR-424	CLIP-seq
MIRT1095691	hsa-miR-4436b-3p	CLIP-seq
MIRT1095692	hsa-miR-4530	CLIP-seq
MIRT1095693	hsa-miR-4649-3p	CLIP-seq
MIRT1095694	hsa-miR-4653-5p	CLIP-seq
MIRT1095695	hsa-miR-4690-5p	CLIP-seq
MIRT1095696	hsa-miR-4721	CLIP-seq
MIRT1095697	hsa-miR-497	CLIP-seq
MIRT1095698	hsa-miR-761	CLIP-seq
MIRT2025705	hsa-miR-4260	CLIP-seq
MIRT2025706	hsa-miR-4324	CLIP-seq
MIRT2256889	hsa-miR-3144-5p	CLIP-seq
MIRT2256890	hsa-miR-711	CLIP-seq
MIRT2558294	hsa-miR-1208	CLIP-seq
MIRT2558295	hsa-miR-1224-3p	CLIP-seq
MIRT2558296	hsa-miR-1260	CLIP-seq
MIRT2558297	hsa-miR-1260b	CLIP-seq
MIRT2558298	hsa-miR-1280	CLIP-seq
MIRT2558299	hsa-miR-1294	CLIP-seq
MIRT1095681	hsa-miR-15a	CLIP-seq
MIRT1095682	hsa-miR-15b	CLIP-seq
MIRT1095683	hsa-miR-16	CLIP-seq
MIRT1095684	hsa-miR-195	CLIP-seq
MIRT2558300	hsa-miR-2110	CLIP-seq
MIRT1095685	hsa-miR-214	CLIP-seq
MIRT2558301	hsa-miR-3127-3p	CLIP-seq
MIRT1095686	hsa-miR-3182	CLIP-seq
MIRT2558302	hsa-miR-3189-3p	CLIP-seq
MIRT1095687	hsa-miR-3616-3p	CLIP-seq
MIRT1095688	hsa-miR-3619-5p	CLIP-seq
MIRT2558303	hsa-miR-3908	CLIP-seq
MIRT1095689	hsa-miR-3921	CLIP-seq
MIRT1095690	hsa-miR-424	CLIP-seq
MIRT2025705	hsa-miR-4260	CLIP-seq
MIRT2558304	hsa-miR-4271	CLIP-seq
MIRT2558305	hsa-miR-4316	CLIP-seq
MIRT2558306	hsa-miR-4420	CLIP-seq
MIRT1095691	hsa-miR-4436b-3p	CLIP-seq
MIRT1095692	hsa-miR-4530	CLIP-seq
MIRT1095693	hsa-miR-4649-3p	CLIP-seq
MIRT2558307	hsa-miR-4651	CLIP-seq
MIRT1095694	hsa-miR-4653-5p	CLIP-seq
MIRT2558308	hsa-miR-4677-3p	CLIP-seq
MIRT1095695	hsa-miR-4690-5p	CLIP-seq
MIRT1095696	hsa-miR-4721	CLIP-seq
MIRT2558309	hsa-miR-4725-3p	CLIP-seq
MIRT2558310	hsa-miR-4786-5p	CLIP-seq
MIRT2558311	hsa-miR-491-5p	CLIP-seq
MIRT1095697	hsa-miR-497	CLIP-seq
MIRT2558312	hsa-miR-548g	CLIP-seq
MIRT2558313	hsa-miR-608	CLIP-seq
MIRT2558314	hsa-miR-665	CLIP-seq
MIRT1095698	hsa-miR-761	CLIP-seq
MIRT2558315	hsa-miR-769-5p	CLIP-seq
MIRT2558294	hsa-miR-1208	CLIP-seq
MIRT2558295	hsa-miR-1224-3p	CLIP-seq
MIRT2558296	hsa-miR-1260	CLIP-seq
MIRT2558297	hsa-miR-1260b	CLIP-seq
MIRT2558298	hsa-miR-1280	CLIP-seq
MIRT2683531	hsa-miR-140-3p	CLIP-seq
MIRT1095681	hsa-miR-15a	CLIP-seq
MIRT1095682	hsa-miR-15b	CLIP-seq
MIRT1095683	hsa-miR-16	CLIP-seq
MIRT1095684	hsa-miR-195	CLIP-seq
MIRT2558300	hsa-miR-2110	CLIP-seq
MIRT1095685	hsa-miR-214	CLIP-seq
MIRT2683532	hsa-miR-2467-3p	CLIP-seq
MIRT2683533	hsa-miR-3125	CLIP-seq
MIRT2558301	hsa-miR-3127-3p	CLIP-seq
MIRT1095686	hsa-miR-3182	CLIP-seq
MIRT2558302	hsa-miR-3189-3p	CLIP-seq
MIRT1095687	hsa-miR-3616-3p	CLIP-seq
MIRT1095688	hsa-miR-3619-5p	CLIP-seq
MIRT2683534	hsa-miR-3678-3p	CLIP-seq
MIRT2558303	hsa-miR-3908	CLIP-seq
MIRT2683535	hsa-miR-3916	CLIP-seq
MIRT1095689	hsa-miR-3921	CLIP-seq
MIRT1095690	hsa-miR-424	CLIP-seq
MIRT2025705	hsa-miR-4260	CLIP-seq
MIRT2558304	hsa-miR-4271	CLIP-seq
MIRT2558306	hsa-miR-4420	CLIP-seq
MIRT1095691	hsa-miR-4436b-3p	CLIP-seq
MIRT1095692	hsa-miR-4530	CLIP-seq
MIRT1095693	hsa-miR-4649-3p	CLIP-seq
MIRT2558307	hsa-miR-4651	CLIP-seq
MIRT1095694	hsa-miR-4653-5p	CLIP-seq
MIRT1095695	hsa-miR-4690-5p	CLIP-seq
MIRT1095696	hsa-miR-4721	CLIP-seq
MIRT2558309	hsa-miR-4725-3p	CLIP-seq
MIRT2683536	hsa-miR-4751	CLIP-seq
MIRT2558310	hsa-miR-4786-5p	CLIP-seq
MIRT2558311	hsa-miR-491-5p	CLIP-seq
MIRT1095697	hsa-miR-497	CLIP-seq
MIRT2683537	hsa-miR-518d-5p	CLIP-seq
MIRT2683538	hsa-miR-519b-5p	CLIP-seq
MIRT2683539	hsa-miR-519c-5p	CLIP-seq
MIRT2683540	hsa-miR-520c-5p	CLIP-seq
MIRT2683541	hsa-miR-526a	CLIP-seq
MIRT2558312	hsa-miR-548g	CLIP-seq
MIRT2558313	hsa-miR-608	CLIP-seq
MIRT2558314	hsa-miR-665	CLIP-seq
MIRT1095698	hsa-miR-761	CLIP-seq
MIRT2558315	hsa-miR-769-5p	CLIP-seq
MIRT2683542	hsa-miR-877	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 33961781, 35271311, 36217029, 36931259
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005871	Component	Kinesin complex	IEA
GO:0005874	Component	Microtubule	IEA
GO:0007018	Process	Microtubule-based movement	IBA
GO:0019894	Function	Kinesin binding	IBA

MIM	HGNC	e!Ensembl
620909	21624	ENSG00000137171

Q9NSK0

Protein name

Kinesin light chain 4 (KLC 4) (Kinesin-like protein 8)

Protein function

Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity). {ECO:00002

Family and domains

Pfam

Accession	ID	Position in sequence	Type
PF13424	TPR_12	209 → 285	Repeat
PF13424	TPR_12	293 → 369	Repeat
PF13374	TPR_10	294 → 335	Repeat
PF13424	TPR_12	335 → 409	Repeat
PF13374	TPR_10	465 → 496	Repeat

Sequence

MSGLVLGQRDEPAGHRLSQEEILGSTRLVSQGLEALRSEHQAVLQSLSQTIECLQQGGHE
EGLVHEKARQLRRSMENIELGLSEAQVMLALASHLSTVESEKQKLRAQVRRLCQENQWLR
DELAGTQQRLQRSEQAVAQLEEEKKHLEFLGQLRQYDEDGHTSEEKEGDATKDSLDDLFP
NEEEEDPSNGLSRGQGATAAQQGGYEIPARLRTLHNLVIQYAAQGRYEVAVPLCKQALED
LERTSGRGHPDVATMLNILALVYRDQNKYKEAAHLLNDALSIRESTLGPDHPAVAATLNN
LAVLYGKRGKYKEAEPLCQRALEIREKVLGTNHPDVAKQLNNLALLCQNQGKYEAVERYY
QRALAIYEGQLGPDNPNVARTKNNLASCYLKQGKYAEAETLYKEILTRAHVQEFGSVDDD
HKPIWMHAEEREEMSKSRHHEGGTPYAEYGGWYKACKVSSPTVNTTLRNLGALYRRQGKL
EAAETLEECALRSRRQGTDPISQTKVAELLGESDGRRTSQEGPGDSVKFEGGEDASVAVE
WSGDGSGTLQRSGSLGKIRDVLRRSSELLVRKLQGTEPRPSSSNMKRAASLNYLNQPSAA
PLQVSRGLSASTMDLSSSS

Sequence length

619

Interactions

View interactions

	KEGG		Reactome
	Motor proteins Alzheimer disease Parkinson disease Amyotrophic lateral sclerosis Huntington disease Prion disease Pathways of neurodegeneration - multiple diseases Salmonella infection		MHC class II antigen presentation RHO GTPases activate KTN1 COPI-dependent Golgi-to-ER retrograde traffic Kinesins

KLC4 (kinesin light chain 4)