CCNF (cyclin F)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 899 |
| Gene name | Cyclin F |
| Gene symbol | CCNF |
| Synonyms (NCBI Gene) |
FBX1FBXO1FTDALS5
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| Chromosome | 16 |
| Chromosome location | 16p13.3 |
| Summary | This gene encodes a member of the cyclin family. Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases. This member also belongs to the F-box protein family which is characte |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P41002 | ||||||||||||||||||||
| Protein name | Cyclin-F (F-box only protein 1) | ||||||||||||||||||||
| Protein function | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:20596027, PubMed:22632967, PubMed:26818844 | ||||||||||||||||||||
| PDB | 9CB3 | ||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed, with expression detected in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:7813445}. | ||||||||||||||||||||
| Sequence |
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| Sequence length | 786 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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