RPS6KA4 (ribosomal protein S6 kinase A4)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 8986 |
| Gene name | Ribosomal protein S6 kinase A4 |
| Gene symbol | RPS6KA4 |
| Synonyms (NCBI Gene) |
MSK2RSK-BS6K-alpha-4
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| Chromosome | 11 |
| Chromosome location | 11q13.1 |
| Summary | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including CREB1 and ATF1. The encoded protein can also pho |
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miRNA
miRNA information provided by mirtarbase database.
266
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O75676 | ||||||||||||||||||||
| Protein name | Ribosomal protein S6 kinase alpha-4 (S6K-alpha-4) (EC 2.7.11.1) (90 kDa ribosomal protein S6 kinase 4) (Nuclear mitogen- and stress-activated protein kinase 2) (Ribosomal protein kinase B) (RSKB) | ||||||||||||||||||||
| Protein function | Serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factor RELA, and that contributes to gene activation by hi | ||||||||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 772 | ||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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