ATG16L2 (autophagy related 16 like 2)

Gene
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
89849
Gene name Gene Name - the full gene name approved by the HGNC.
Autophagy related 16 like 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ATG16L2
Synonyms (NCBI Gene) Gene synonyms aliases
ATG16B, WDR80
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q13.4
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(1)
miRTarBase ID miRNA Experiments Reference
MIRT017121 hsa-miR-335-5p Microarray 18185580
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide all(9)
GO ID Ontology Definition Evidence Reference
GO:0000045 Process Autophagosome assembly IBA 21873635
GO:0000045 Process Autophagosome assembly ISS
GO:0000421 Component Autophagosome membrane IBA 21873635
GO:0005654 Component Nucleoplasm IDA
GO:0005776 Component Autophagosome ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
MIM HGNC e!Ensembl
618716 25464 ENSG00000168010
Protein
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
UniProt ID Q8NAA4
Protein name Protein Atg16l2 (APG16-like 2) (Autophagy-related protein 16-2) (WD repeat-containing protein 80)
Protein function May play a role in regulating epithelial homeostasis in an ATG16L1-dependent manner.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF08614 ATG16 17 → 207 Autophagy protein 16 (ATG16) Coiled-coil
PF00400 WD40 327 → 364 WD domain, G-beta repeat Repeat
PF00400 WD40 412 → 450 WD domain, G-beta repeat Repeat
PF00400 WD40 493 → 530 WD domain, G-beta repeat Repeat
PF00400 WD40 537 → 576 WD domain, G-beta repeat Repeat
Sequence 
MAGPGVPGAPAARWKRHIVRQLRLRDRTQKALFLELVPAYNHLLEKAELLDKFSKKLQPE
PNSVTPTTHQGPWEESELDSDQVPSLVALRVKWQEEEEGLRLVCGEMAYQVVEKGAALGT
LESELQQRQSRLAALEARVAQLREARAQQAQQVEEWRAQNAVQRAAYEALRAHVGLREAA
LRRLQEEARDLLERLVQRKARAAAERNLRNERRERAKQARVSQELKKAAKRTVSISEGPD
TLGDGMRERRETLALAPEPEPLEKEACEKWKRPFRSASATSLTLSHCVDVVKGLLDFKKR
RGHSIGGAPEQRYQIIPVCVAARLPTRAQDVLDAHLSEVNAVRFGPNSSLLATGGADRLI
HLWNVVGSRLEANQTLEGAGGSITSVDFDPSGYQVLAATYNQAAQLWKVGEAQSKETLSG
HKDKVTAAKFKLTRHQAVTGSRDRTVKEWDLGRAYCSRTINVLSYCNDVVCGDHIIISGH
NDQKIRFWDSRGPHCTQVIPVQGRVTSLSLSHDQLHLLSCSRDNTLKVIDLRVSNIRQVF
RADGFKCGSDWTKAVFSPDRSYALAGSCDGALYIWDVDTGKLESRLQGPHCAAVNAVAWC
YSGSHMVSVDQGRKVVLWQ
Sequence length 619
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
  KEGG  
  Autophagy - animal  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Show/Hide Unknown Diseases (2)
Unknown
Disease term Disease name Evidence References Source
Crohn disease Crohn Disease 23850713 ClinVar
Coronary artery disease Coronary artery disease GWAS
Show/Hide Text Mining Associations (14)
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 29259263
Alzheimer Disease Associate 40244264
Amyotrophic Lateral Sclerosis Associate 33523907
Carcinoma Non Small Cell Lung Associate 29454863
Carcinoma Renal Cell Associate 31626592
Coronary Artery Disease Associate 32514122
Crohn Disease Associate 26503572
Drug Related Side Effects and Adverse Reactions Associate 31692259
Kidney Neoplasms Associate 26208877
Lung Neoplasms Associate 32514122