Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	89801
Gene name	Protein phosphatase 1 regulatory subunit 3F
Gene symbol	PPP1R3F
Synonyms (NCBI Gene)	HB2ELL0XNC01-7P3.1R3F
Chromosome	X
Chromosome location	Xp11.23
Summary	This gene encodes a protein that has been identified as one of several type-1 protein phosphatase (PP1) regulatory subunits. One or two of these subunits, together with the well-conserved catalytic subunit, can form the PP1 holoenzyme, where the regulator

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miRTarBase ID	miRNA	Experiments	Reference
MIRT720055	hsa-miR-548n	HITS-CLIP	19536157
MIRT720054	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT720053	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT720051	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT720052	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT720050	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT720049	hsa-miR-520f-5p	HITS-CLIP	19536157
MIRT720048	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT720047	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT720046	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT720055	hsa-miR-548n	HITS-CLIP	19536157
MIRT720054	hsa-miR-548az-5p	HITS-CLIP	19536157
MIRT720053	hsa-miR-548t-5p	HITS-CLIP	19536157
MIRT720051	hsa-miR-6777-3p	HITS-CLIP	19536157
MIRT720052	hsa-miR-6887-3p	HITS-CLIP	19536157
MIRT720050	hsa-miR-6795-3p	HITS-CLIP	19536157
MIRT720049	hsa-miR-520f-5p	HITS-CLIP	19536157
MIRT720048	hsa-miR-6509-3p	HITS-CLIP	19536157
MIRT720047	hsa-miR-4436b-5p	HITS-CLIP	19536157
MIRT720046	hsa-miR-6826-3p	HITS-CLIP	19536157
MIRT1256956	hsa-miR-1236	CLIP-seq
MIRT1256957	hsa-miR-127-5p	CLIP-seq
MIRT1256958	hsa-miR-134	CLIP-seq
MIRT1256959	hsa-miR-149	CLIP-seq
MIRT1256960	hsa-miR-15a	CLIP-seq
MIRT1256961	hsa-miR-15b	CLIP-seq
MIRT1256962	hsa-miR-16	CLIP-seq
MIRT1256963	hsa-miR-195	CLIP-seq
MIRT1256964	hsa-miR-214	CLIP-seq
MIRT1256965	hsa-miR-3118	CLIP-seq
MIRT1256966	hsa-miR-3136-5p	CLIP-seq
MIRT1256967	hsa-miR-3164	CLIP-seq
MIRT1256968	hsa-miR-3607-5p	CLIP-seq
MIRT1256969	hsa-miR-3619-5p	CLIP-seq
MIRT1256970	hsa-miR-424	CLIP-seq
MIRT1256971	hsa-miR-4252	CLIP-seq
MIRT1256972	hsa-miR-4292	CLIP-seq
MIRT1256973	hsa-miR-4308	CLIP-seq
MIRT1256974	hsa-miR-4439	CLIP-seq
MIRT1256975	hsa-miR-4501	CLIP-seq
MIRT1256976	hsa-miR-4513	CLIP-seq
MIRT1256977	hsa-miR-4690-5p	CLIP-seq
MIRT1256978	hsa-miR-4691-5p	CLIP-seq
MIRT1256979	hsa-miR-497	CLIP-seq
MIRT1256980	hsa-miR-604	CLIP-seq
MIRT1256981	hsa-miR-647	CLIP-seq
MIRT1256982	hsa-miR-653	CLIP-seq
MIRT1256983	hsa-miR-761	CLIP-seq
MIRT2075649	hsa-miR-1182	CLIP-seq
MIRT2075650	hsa-miR-1224-3p	CLIP-seq
MIRT1256956	hsa-miR-1236	CLIP-seq
MIRT2075651	hsa-miR-1255a	CLIP-seq
MIRT2075652	hsa-miR-1255b	CLIP-seq
MIRT2075653	hsa-miR-1260	CLIP-seq
MIRT2075654	hsa-miR-1260b	CLIP-seq
MIRT2075655	hsa-miR-1280	CLIP-seq
MIRT1256959	hsa-miR-149	CLIP-seq
MIRT2075656	hsa-miR-185	CLIP-seq
MIRT2075657	hsa-miR-188-3p	CLIP-seq
MIRT2075658	hsa-miR-2110	CLIP-seq
MIRT1256966	hsa-miR-3136-5p	CLIP-seq
MIRT2075659	hsa-miR-3150a-3p	CLIP-seq
MIRT2075660	hsa-miR-329	CLIP-seq
MIRT2075661	hsa-miR-362-3p	CLIP-seq
MIRT2075662	hsa-miR-3941	CLIP-seq
MIRT1256971	hsa-miR-4252	CLIP-seq
MIRT1256972	hsa-miR-4292	CLIP-seq
MIRT2075663	hsa-miR-4306	CLIP-seq
MIRT1256973	hsa-miR-4308	CLIP-seq
MIRT1256974	hsa-miR-4439	CLIP-seq
MIRT2075664	hsa-miR-4450	CLIP-seq
MIRT2075665	hsa-miR-4453	CLIP-seq
MIRT2075666	hsa-miR-4491	CLIP-seq
MIRT2075667	hsa-miR-4514	CLIP-seq
MIRT2075668	hsa-miR-4538	CLIP-seq
MIRT2075669	hsa-miR-4644	CLIP-seq
MIRT2075670	hsa-miR-4657	CLIP-seq
MIRT1256978	hsa-miR-4691-5p	CLIP-seq
MIRT2075671	hsa-miR-4692	CLIP-seq
MIRT2075672	hsa-miR-532-3p	CLIP-seq
MIRT2075673	hsa-miR-603	CLIP-seq
MIRT2075674	hsa-miR-943	CLIP-seq
MIRT2075650	hsa-miR-1224-3p	CLIP-seq
MIRT1256956	hsa-miR-1236	CLIP-seq
MIRT2075653	hsa-miR-1260	CLIP-seq
MIRT2075654	hsa-miR-1260b	CLIP-seq
MIRT2075655	hsa-miR-1280	CLIP-seq
MIRT1256959	hsa-miR-149	CLIP-seq
MIRT2302264	hsa-miR-369-3p	CLIP-seq
MIRT2302265	hsa-miR-374a	CLIP-seq
MIRT2302266	hsa-miR-374b	CLIP-seq
MIRT2302267	hsa-miR-410	CLIP-seq
MIRT1256971	hsa-miR-4252	CLIP-seq
MIRT1256972	hsa-miR-4292	CLIP-seq
MIRT1256973	hsa-miR-4308	CLIP-seq
MIRT1256978	hsa-miR-4691-5p	CLIP-seq
MIRT2075672	hsa-miR-532-3p	CLIP-seq
MIRT2075657	hsa-miR-188-3p	CLIP-seq
MIRT2439591	hsa-miR-100	CLIP-seq
MIRT2439592	hsa-miR-642a	CLIP-seq
MIRT2439593	hsa-miR-99a	CLIP-seq
MIRT2439594	hsa-miR-99b	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000164	Component	Protein phosphatase type 1 complex	IBA
GO:0005979	Process	Regulation of glycogen biosynthetic process	IBA
GO:0005979	Process	Regulation of glycogen biosynthetic process	IDA	21668450
GO:0008157	Function	Protein phosphatase 1 binding	IBA
GO:0016020	Component	Membrane	IDA	21668450
GO:0016020	Component	Membrane	IEA
GO:0019903	Function	Protein phosphatase binding	IPI	21668450
GO:2000465	Process	Regulation of glycogen (starch) synthase activity	IDA	21668450
GO:2001069	Function	Glycogen binding	IBA
GO:2001069	Function	Glycogen binding	IDA	21668450

MIM	HGNC	e!Ensembl
301104	14944	ENSG00000049769

Q6ZSY5

Protein name

Protein phosphatase 1 regulatory subunit 3F (R3F)

Protein function

Glycogen-targeting subunit for protein phosphatase 1 (PP1).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03370	CBM_21	151 → 284	Carbohydrate/starch-binding module (family 21)	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in brain, skeletal muscle and heart. {ECO:0000269|PubMed:21668450}.

Sequence

MARTAPVEPPLRHSAPPSPAAGEPRTSVEAAVAPRRVLFADEALGLPLAQLRRYRPWGGP
GAGKMAAAAGQDGGGGGGADEDDDGEDGDEGEEEEEACPEPSPLCPVPAGGGFYLVPTFS
LPPAPGRLERLGRVMVELEALLPPPGAVPGGAGVWVPGGRPPVLRGLVRVLNRSFEKAVH
VRASHDGWASFCDHPARYVPRSPPWAGAGGTGAGDPILDPGLGLGPGQASASSPDDGGRT
DRFAFQLPFAEGAGDGARLDFVVRYETPEGTFWANNHGRNYTVLLRIAPAPTPTDAEGLP
QQQQLPQLEPQPECQGPVEAEARQLKSCMKPVRRRPAEEELKTKNMDDNTFAMAEHPDVQ
ESVGPLVAPTPLRPWPQMTLQVSDVPMTGNPAEEGDVPRSSPPVAFTEVLQAPAIRIPPS
SPLCGLGGSPRDQASGPDASEGATGPFLEPSQQQAEATWGVSSENGGGLEAVSGSEELLG
EDTIDQELEQLYLSHLSRLRAAVAAGGAGGGGEGSTDGGMSPSHPLGILTDRDLILKWPG
PERALNSALAEEITLHYARLGRGVELIKDTEDPDDEGEGEEGLSVTPSSPEGDSPKESPP
EILSGARSVVATMGDVWLPWAEGSGCDGPVVLGTEGQFIGDPEKGMGKDTSSLHMNRVIA
GVTESLGEAGTEAQIEVTSEWAGSLDPISGKEPASPVLLQGQNPTLLSPLGAEVCLSSVA
RPHVSSQDEKDAGPSLEPPKKSPTLAVPAECVCALPPQLRGPLTQTLGVLAGLVVVPVAL
NSGVSLLVLALCLSLAWFS

Sequence length

799

Interactions

View interactions

	KEGG
	Insulin signaling pathway

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
PPP1R3F Associated Neurodevelopmental Disorder	Uncertain significance	rs2519212547	RCV004555965

Show/Hide Text Mining Associations (10)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Astrocytoma	Associate	37531237
Autism Spectrum Disorder	Associate	30016992, 37531237
Autistic Disorder	Associate	37531237
Cerebellar Diseases	Associate	37531237
Colorectal Neoplasms	Stimulate	34145793
Developmental Disabilities	Associate	37531237
Intellectual Disability	Associate	37531237
Mental Retardation X Linked	Associate	37531237
Metabolic Syndrome	Associate	37531237
Seizures	Associate	37531237

PPP1R3F (protein phosphatase 1 regulatory subunit 3F)