NAV2 (neuron navigator 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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89797 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Neuron navigator 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NAV2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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HELAD1, POMFIL2, RAINB1, STEERIN2, UNC53H2 |
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Chromosome
Chromosome number
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11 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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11p15.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q8IVL1 | ||||||||||
| Protein name | Neuron navigator 2 (EC 3.6.4.12) (Helicase APC down-regulated 1) (Pore membrane and/or filament-interacting-like protein 2) (Retinoic acid inducible in neuroblastoma 1) (Steerin-2) (Unc-53 homolog 2) (unc53H2) | ||||||||||
| Protein function | Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs. | ||||||||||
| PDB | 2YRN | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers. {ECO:0000269|PubMed:11904404, ECO:0000269|PubMed:12062803, ECO | ||||||||||
| Sequence |
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| Sequence length | 2488 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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