COX1 (-)

Gene

• Entrez ID: 8923218
• Gene name: -
• Gene symbol: COX1
• Synonyms (NCBI Gene): -
• Chromosome: MT
• Chromosome location: -

Transcription factors

Transcription factor	Regulation	Reference
MLL4	Unknown	19570036
NFKB1	Unknown	19570036
NR3C1	Unknown	19570036
RELA	Unknown	19570036

Other IDs

• MIM: N/A
• HGNC: N/A
• e!Ensembl: N/A

Interactions View interactions

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
BECKWITH-WIEDEMANN SYNDROME	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
BETA-THALASSEMIA	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARCINOMA	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CARDIOMYOPATHIES	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CEREBELLAR ATAXIA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
CLEFT PALATE AND BILATERAL CLEFT LIP	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEAFNESS, AMINOGLYCOSIDE-INDUCED	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEAFNESS, NONSYNDROMIC SENSORINEURAL, MITOCHONDRIAL	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
DEAFNESS, SENSORINEURAL, AUTOSOMAL-MITOCHONDRIAL TYPE	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
HYPERTROPHY	—	CTD	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MACULAR DYSTROPHY, RETINAL, 1, NORTH CAROLINA TYPE	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MELAS SYNDROME	—	CTD, Disgenet CTD, Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX IV DEFICIENCY, NUCLEAR TYPE 1	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL COMPLEX V DEFICIENCY, MITOCHONDRIAL TYPE 1	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MITOCHONDRIAL DISEASES	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
NEUROPATHY, ATAXIA, AND RETINITIS PIGMENTOSA	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OPTIC ATROPHY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
OPTIC ATROPHY, HEREDITARY, LEBER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
POLYDACTYLY, PREAXIAL II	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRADER-WILLI SYNDROME	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PRIMARY CARDIOMYOPATHY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ROD-CONE DYSTROPHY	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
SILVER-RUSSELL SYNDROME 1	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
ULNAR POLYDACTYLY OF FINGERS	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
WILMS TUMOR 2	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
WOLF-HIRSCHHORN SYNDROME	—	HPO	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Acrocephalosyndactylia	Associate	31821324	★☆☆☆☆ Found in Text Mining only
Acromegaly	Stimulate	32171274	★☆☆☆☆ Found in Text Mining only
Adenocarcinoma	Associate	11005569, 11920472	★☆☆☆☆ Found in Text Mining only
Adenoma	Associate	23778325	★☆☆☆☆ Found in Text Mining only
Adenoma Pleomorphic	Associate	22507323	★☆☆☆☆ Found in Text Mining only
Adenomatous Polyposis Coli	Associate	23599153	★☆☆☆☆ Found in Text Mining only
Alzheimer Disease	Associate	30040709	★☆☆☆☆ Found in Text Mining only
Angina Unstable	Inhibit	12871422	★☆☆☆☆ Found in Text Mining only
Arthritis	Associate	26225917	★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Associate	10719816	★☆☆☆☆ Found in Text Mining only
Arthritis Rheumatoid	Inhibit	12296865	★☆☆☆☆ Found in Text Mining only
Asthma	Associate	23441755	★☆☆☆☆ Found in Text Mining only
Asthma Aspirin Induced	Associate	23441755	★☆☆☆☆ Found in Text Mining only
Asthma Nasal Polyps And Aspirin Intolerance	Inhibit	17622692	★☆☆☆☆ Found in Text Mining only
Atherosclerosis	Associate	36690661	★☆☆☆☆ Found in Text Mining only
Atrophy	Associate	14717921	★☆☆☆☆ Found in Text Mining only
Barrett Esophagus	Associate	28206968	★☆☆☆☆ Found in Text Mining only
Bipolar Disorder	Inhibit	20038946	★☆☆☆☆ Found in Text Mining only
Blood Platelet Disorders	Associate	10942685, 22972377, 27554763	★☆☆☆☆ Found in Text Mining only
Brain Ischemia	Associate	31821324	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	27121313, 32085795, 37510369, 37798736	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Stimulate	27121313	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Associate	15075004, 17624243, 19205707, 36292984	★☆☆☆☆ Found in Text Mining only
Carcinoma Non Small Cell Lung	Associate	11920472	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Stimulate	23886173	★☆☆☆☆ Found in Text Mining only
Carcinoma Renal Cell	Associate	26339385	★☆☆☆☆ Found in Text Mining only
Carcinoma Squamous Cell	Associate	28886030	★☆☆☆☆ Found in Text Mining only
Cardiomyopathies	Associate	20978534	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Cardiomyopathy Dilated	Associate	33303703	★☆☆☆☆ Found in Text Mining only
Cardiovascular Diseases	Associate	10942685	★☆☆☆☆ Found in Text Mining only
Cerebral Infarction	Associate	31735164	★☆☆☆☆ Found in Text Mining only
Cerebral Small Vessel Diseases	Associate	31735164	★☆☆☆☆ Found in Text Mining only
Cholangiocarcinoma	Associate	11115827, 24839005, 40489465	★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Stimulate	17653443	★☆☆☆☆ Found in Text Mining only
Colitis Ulcerative	Associate	32164249	★☆☆☆☆ Found in Text Mining only
Colonic Neoplasms	Associate	27554763	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	15075004, 15816542, 20026301, 20689513, 21389643	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Stimulate	23222413	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Associate	27919931, 31821324	★☆☆☆☆ Found in Text Mining only
Coronary Artery Disease	Inhibit	31979197	★☆☆☆☆ Found in Text Mining only
Cystic Fibrosis	Stimulate	16517580	★☆☆☆☆ Found in Text Mining only
Cytochrome c Oxidase Deficiency	Associate	15306853, 9832034	★☆☆☆☆ Found in Text Mining only
Deafness	Associate	16152638, 38084023	★☆☆☆☆ Found in Text Mining only
Death	Associate	24473763	★☆☆☆☆ Found in Text Mining only
Dental Plaque	Associate	36690661	★☆☆☆☆ Found in Text Mining only
Dermatitis Atopic 3	Associate	8994519	★☆☆☆☆ Found in Text Mining only
Diabetes Gestational	Inhibit	25437179	★☆☆☆☆ Found in Text Mining only
Diverticular Diseases	Associate	24758697	★☆☆☆☆ Found in Text Mining only
Down Syndrome	Associate	33418267	★☆☆☆☆ Found in Text Mining only
Dysmenorrhea	Stimulate	17264103	★☆☆☆☆ Found in Text Mining only
Epilepsy	Associate	30030837	★☆☆☆☆ Found in Text Mining only
Farber Lipogranulomatosis	Associate	17107625	★☆☆☆☆ Found in Text Mining only
Fibrosis	Associate	30391585	★☆☆☆☆ Found in Text Mining only
Gastritis	Associate	11076873	★☆☆☆☆ Found in Text Mining only
Glaucoma Open Angle	Associate	27217714, 29610859	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Associate	33919029	★☆☆☆☆ Found in Text Mining only
Glioma	Associate	11877441	★☆☆☆☆ Found in Text Mining only
HAIR AN syndrome	Associate	32601317	★☆☆☆☆ Found in Text Mining only
Hearing Disorders	Associate	16152638	★☆☆☆☆ Found in Text Mining only
Hereditary leiomyomatosis and renal cell cancer	Associate	25139349	★☆☆☆☆ Found in Text Mining only
Huntington Disease	Inhibit	11905993	★☆☆☆☆ Found in Text Mining only
Huntington Disease	Associate	38447791	★☆☆☆☆ Found in Text Mining only
Idiopathic Pulmonary Fibrosis	Associate	24473763	★☆☆☆☆ Found in Text Mining only
Immune Reconstitution Inflammatory Syndrome	Stimulate	29135655	★☆☆☆☆ Found in Text Mining only
Inflammation	Associate	10719816, 14517073, 18094001, 20818651, 30030837, 30292675, 31759362, 34256950	★☆☆☆☆ Found in Text Mining only
Keratoconus	Associate	27783701	★☆☆☆☆ Found in Text Mining only
Leigh Disease	Associate	11782424	★☆☆☆☆ Found in Text Mining only
Leiomyoma	Stimulate	34256950	★☆☆☆☆ Found in Text Mining only
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	19506164	★☆☆☆☆ Found in Text Mining only
Malaria	Associate	20144201	★☆☆☆☆ Found in Text Mining only
Melanoma	Associate	15251468	★☆☆☆☆ Found in Text Mining only
Mitochondrial Diseases	Associate	22134189, 25844556	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Mucocutaneous Lymph Node Syndrome	Stimulate	35154107	★☆☆☆☆ Found in Text Mining only
Multiple Myeloma	Associate	26724804	★☆☆☆☆ Found in Text Mining only
Multiple Sclerosis	Associate	32655763	★☆☆☆☆ Found in Text Mining only
Muscular Diseases	Associate	20978534	★☆☆☆☆ Found in Text Mining only
Myelodysplastic Syndromes	Associate	11849212, 21447369	★☆☆☆☆ Found in Text Mining only
Myositis	Stimulate	18094001	★☆☆☆☆ Found in Text Mining only
Myotonic Dystrophy	Associate	38240888	★☆☆☆☆ Found in Text Mining only
Nasal Polyps	Associate	16517580, 23441755	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	11115827, 11853083, 12784332, 15016321, 15328521, 15347673, 16671096, 16803521, 17201156, 17624243, 18997734, 20818651, 21389643, 22134189, 26339385, 29482584, 31673122	★☆☆☆☆ Found in Text Mining only
Neoplasms	Stimulate	23886173, 28277128, 29486731, 31347609	★☆☆☆☆ Found in Text Mining only
Neurodegenerative Diseases	Associate	11905993, 30040709	★☆☆☆☆ Found in Text Mining only
Neuroinflammatory Diseases	Associate	33113430	★☆☆☆☆ Found in Text Mining only
Nonsyndromic Deafness	Associate	16152638	★☆☆☆☆ Found in Text Mining only
Obesity	Associate	28730835	★☆☆☆☆ Found in Text Mining only
Optic Atrophy Hereditary Leber	Associate	1322638	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Associate	11891188, 15347673, 29482584, 30377203, 36012230	★☆☆☆☆ Found in Text Mining only
Pancreatic Neoplasms	Associate	16671096	★☆☆☆☆ Found in Text Mining only
Peptic Ulcer	Associate	25243161	★☆☆☆☆ Found in Text Mining only
Pituitary ACTH Hypersecretion	Stimulate	32171274	★☆☆☆☆ Found in Text Mining only
Pituitary Neoplasms	Stimulate	32171274	★☆☆☆☆ Found in Text Mining only
Primary Ovarian Insufficiency	Associate	26225554	★☆☆☆☆ Found in Text Mining only
Prolactinoma	Stimulate	32171274	★☆☆☆☆ Found in Text Mining only
Prostatic Neoplasms	Associate	10484067, 19267350	★☆☆☆☆ Found in Text Mining only
Psoriasis	Stimulate	31480263	★☆☆☆☆ Found in Text Mining only
Pulmonary Disease Chronic Obstructive	Associate	34831227	★☆☆☆☆ Found in Text Mining only
Scleroderma Systemic	Associate	24473763	★☆☆☆☆ Found in Text Mining only
Smoke Inhalation Injury	Stimulate	23242413	★☆☆☆☆ Found in Text Mining only
Spondylitis Ankylosing	Stimulate	26225917	★☆☆☆☆ Found in Text Mining only
Status Asthmaticus	Associate	8994519	★☆☆☆☆ Found in Text Mining only
Stomach Neoplasms	Associate	31673122, 31835645	★☆☆☆☆ Found in Text Mining only
Thrombocythemia Essential	Associate	19887674	★☆☆☆☆ Found in Text Mining only
Torsades de Pointes	Associate	29788265	★☆☆☆☆ Found in Text Mining only
Ulcer	Associate	11076873	★☆☆☆☆ Found in Text Mining only
Uterine Cervical Neoplasms	Associate	16803521	★☆☆☆☆ Found in Text Mining only
Uterine Neoplasms	Associate	17044934	★☆☆☆☆ Found in Text Mining only
Vasospasm Intracranial	Associate	36864213	★☆☆☆☆ Found in Text Mining only