Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8915
Gene name Gene Name - the full gene name approved by the HGNC.	BCL10 immune signaling adaptor
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	BCL10
Synonyms (NCBI Gene) Gene synonyms aliases	CARMEN, CIPER, CLAP, IMD37, c-E10, mE10
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p22.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB.

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SNP ID	Visualize variation	Clinical significance	Consequence
rs121918314	G>A,C	Pathogenic	Stop gained, missense variant, coding sequence variant
rs370432633	G>A	Pathogenic	Missense variant, coding sequence variant
rs387906350	A>-,AA	Pathogenic	Coding sequence variant, frameshift variant
rs387906351	T>-,TT	Pathogenic	Coding sequence variant, frameshift variant
rs587776630	->T	Pathogenic	Coding sequence variant, frameshift variant
rs587776631	T>-	Pathogenic	Coding sequence variant, frameshift variant
rs587776632	A>-,AAA	Pathogenic	Coding sequence variant, frameshift variant
rs587776633	->T	Pathogenic	Coding sequence variant, frameshift variant
rs587776634	TGCCTACTTCTAGAACA>-	Pathogenic	Coding sequence variant, frameshift variant
rs587776635	T>-	Pathogenic	Coding sequence variant, frameshift variant
rs587776636	->A	Pathogenic	Coding sequence variant, frameshift variant
rs587776637	TCT>-	Pathogenic	Coding sequence variant, inframe deletion

Show/Hide all(371)

miRTarBase ID	miRNA	Experiments	Reference
MIRT019608	hsa-miR-340-5p	Sequencing	20371350
MIRT019968	hsa-miR-375	Microarray	20215506
MIRT028199	hsa-miR-33a-5p	Sequencing	20371350
MIRT048426	hsa-miR-100-5p	CLASH	23622248
MIRT053389	hsa-miR-106a-5p	Luciferase reporter assay, Western blot	23807165
MIRT053389	hsa-miR-106a-5p	Luciferase reporter assay, Western blot	23807165
MIRT669374	hsa-miR-4717-5p	HITS-CLIP	23824327
MIRT669373	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT669372	hsa-miR-6861-5p	HITS-CLIP	23824327
MIRT080491	hsa-miR-3607-3p	HITS-CLIP	23824327
MIRT669371	hsa-miR-197-5p	HITS-CLIP	23824327
MIRT669370	hsa-miR-3132	HITS-CLIP	23824327
MIRT669369	hsa-miR-3686	HITS-CLIP	23824327
MIRT669368	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT669367	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT669366	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT669365	hsa-miR-1229-5p	HITS-CLIP	23824327
MIRT669364	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT669363	hsa-miR-3122	HITS-CLIP	23824327
MIRT669362	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT669361	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT669360	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT290873	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT660339	hsa-miR-4738-3p	HITS-CLIP	23824327
MIRT660338	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT660337	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT290873	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT660339	hsa-miR-4738-3p	HITS-CLIP	23824327
MIRT660338	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT660337	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT733544	hsa-miR-155-5p	Luciferase reporter assay, Western blotting, qRT-PCR, ELISA	32042774
MIRT669374	hsa-miR-4717-5p	HITS-CLIP	23824327
MIRT669373	hsa-miR-383-3p	HITS-CLIP	23824327
MIRT669372	hsa-miR-6861-5p	HITS-CLIP	23824327
MIRT080491	hsa-miR-3607-3p	HITS-CLIP	23824327
MIRT669371	hsa-miR-197-5p	HITS-CLIP	23824327
MIRT669370	hsa-miR-3132	HITS-CLIP	23824327
MIRT669369	hsa-miR-3686	HITS-CLIP	23824327
MIRT669368	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT669367	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT669366	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT669365	hsa-miR-1229-5p	HITS-CLIP	23824327
MIRT669364	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT669363	hsa-miR-3122	HITS-CLIP	23824327
MIRT669362	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT669361	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT669360	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT290873	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT660339	hsa-miR-4738-3p	HITS-CLIP	23824327
MIRT660338	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT660337	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT290873	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT660339	hsa-miR-4738-3p	HITS-CLIP	23824327
MIRT660338	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT660337	hsa-miR-2681-5p	HITS-CLIP	23824327
MIRT818104	hsa-miR-105	CLIP-seq
MIRT818105	hsa-miR-1182	CLIP-seq
MIRT818106	hsa-miR-1273e	CLIP-seq
MIRT818107	hsa-miR-1294	CLIP-seq
MIRT818108	hsa-miR-129-5p	CLIP-seq
MIRT818109	hsa-miR-151-3p	CLIP-seq
MIRT818110	hsa-miR-2278	CLIP-seq
MIRT818111	hsa-miR-3121-3p	CLIP-seq
MIRT818112	hsa-miR-3155	CLIP-seq
MIRT818113	hsa-miR-3155b	CLIP-seq
MIRT818114	hsa-miR-320a	CLIP-seq
MIRT818115	hsa-miR-320b	CLIP-seq
MIRT818116	hsa-miR-320c	CLIP-seq
MIRT818117	hsa-miR-320d	CLIP-seq
MIRT818118	hsa-miR-3647-3p	CLIP-seq
MIRT818119	hsa-miR-3671	CLIP-seq
MIRT818120	hsa-miR-371-5p	CLIP-seq
MIRT818121	hsa-miR-371b-5p	CLIP-seq
MIRT818122	hsa-miR-384	CLIP-seq
MIRT818123	hsa-miR-3926	CLIP-seq
MIRT818124	hsa-miR-3976	CLIP-seq
MIRT818125	hsa-miR-4252	CLIP-seq
MIRT818126	hsa-miR-4261	CLIP-seq
MIRT818127	hsa-miR-4282	CLIP-seq
MIRT818128	hsa-miR-4307	CLIP-seq
MIRT818129	hsa-miR-4429	CLIP-seq
MIRT818130	hsa-miR-4433	CLIP-seq
MIRT818131	hsa-miR-4470	CLIP-seq
MIRT818132	hsa-miR-4486	CLIP-seq
MIRT818133	hsa-miR-4496	CLIP-seq
MIRT818134	hsa-miR-4517	CLIP-seq
MIRT818135	hsa-miR-451b	CLIP-seq
MIRT818136	hsa-miR-4635	CLIP-seq
MIRT818137	hsa-miR-4649-5p	CLIP-seq
MIRT818138	hsa-miR-4684-5p	CLIP-seq
MIRT818139	hsa-miR-4696	CLIP-seq
MIRT818140	hsa-miR-4710	CLIP-seq
MIRT818141	hsa-miR-4719	CLIP-seq
MIRT818142	hsa-miR-4793-3p	CLIP-seq
MIRT818143	hsa-miR-484	CLIP-seq
MIRT818144	hsa-miR-508-5p	CLIP-seq
MIRT818145	hsa-miR-513a-3p	CLIP-seq
MIRT818146	hsa-miR-513c	CLIP-seq
MIRT818147	hsa-miR-514b-5p	CLIP-seq
MIRT818148	hsa-miR-548c-3p	CLIP-seq
MIRT818149	hsa-miR-548p	CLIP-seq
MIRT818150	hsa-miR-548s	CLIP-seq
MIRT818151	hsa-miR-548u	CLIP-seq
MIRT818152	hsa-miR-582-5p	CLIP-seq
MIRT818153	hsa-miR-587	CLIP-seq
MIRT818154	hsa-miR-627	CLIP-seq
MIRT818155	hsa-miR-628-3p	CLIP-seq
MIRT818156	hsa-miR-661	CLIP-seq
MIRT818157	hsa-miR-665	CLIP-seq
MIRT818158	hsa-miR-766	CLIP-seq
MIRT818159	hsa-miR-873	CLIP-seq
MIRT818107	hsa-miR-1294	CLIP-seq
MIRT1545719	hsa-miR-187	CLIP-seq
MIRT818140	hsa-miR-4710	CLIP-seq
MIRT818104	hsa-miR-105	CLIP-seq
MIRT818110	hsa-miR-2278	CLIP-seq
MIRT1941833	hsa-miR-3163	CLIP-seq
MIRT1941834	hsa-miR-340	CLIP-seq
MIRT1941835	hsa-miR-3685	CLIP-seq
MIRT818123	hsa-miR-3926	CLIP-seq
MIRT818127	hsa-miR-4282	CLIP-seq
MIRT818131	hsa-miR-4470	CLIP-seq
MIRT1941836	hsa-miR-4474-5p	CLIP-seq
MIRT818132	hsa-miR-4486	CLIP-seq
MIRT1941837	hsa-miR-4495	CLIP-seq
MIRT818135	hsa-miR-451b	CLIP-seq
MIRT818137	hsa-miR-4649-5p	CLIP-seq
MIRT1941838	hsa-miR-4724-5p	CLIP-seq
MIRT1941839	hsa-miR-4760-5p	CLIP-seq
MIRT818142	hsa-miR-4793-3p	CLIP-seq
MIRT818144	hsa-miR-508-5p	CLIP-seq
MIRT818150	hsa-miR-548s	CLIP-seq
MIRT818151	hsa-miR-548u	CLIP-seq
MIRT818152	hsa-miR-582-5p	CLIP-seq
MIRT1941840	hsa-miR-603	CLIP-seq
MIRT818156	hsa-miR-661	CLIP-seq
MIRT818158	hsa-miR-766	CLIP-seq
MIRT818108	hsa-miR-129-5p	CLIP-seq
MIRT1545719	hsa-miR-187	CLIP-seq
MIRT818110	hsa-miR-2278	CLIP-seq
MIRT2180693	hsa-miR-24	CLIP-seq
MIRT2180694	hsa-miR-3174	CLIP-seq
MIRT2180695	hsa-miR-342-3p	CLIP-seq
MIRT2180696	hsa-miR-3606	CLIP-seq
MIRT2180697	hsa-miR-3622b-5p	CLIP-seq
MIRT818118	hsa-miR-3647-3p	CLIP-seq
MIRT818122	hsa-miR-384	CLIP-seq
MIRT818123	hsa-miR-3926	CLIP-seq
MIRT2180698	hsa-miR-3929	CLIP-seq
MIRT818125	hsa-miR-4252	CLIP-seq
MIRT2180699	hsa-miR-4255	CLIP-seq
MIRT818127	hsa-miR-4282	CLIP-seq
MIRT2180700	hsa-miR-4284	CLIP-seq
MIRT2180701	hsa-miR-4316	CLIP-seq
MIRT2180702	hsa-miR-4326	CLIP-seq
MIRT2180703	hsa-miR-4419b	CLIP-seq
MIRT818130	hsa-miR-4433	CLIP-seq
MIRT818131	hsa-miR-4470	CLIP-seq
MIRT1941836	hsa-miR-4474-5p	CLIP-seq
MIRT2180704	hsa-miR-4478	CLIP-seq
MIRT818132	hsa-miR-4486	CLIP-seq
MIRT818137	hsa-miR-4649-5p	CLIP-seq
MIRT2180705	hsa-miR-4691-5p	CLIP-seq
MIRT818142	hsa-miR-4793-3p	CLIP-seq
MIRT2180706	hsa-miR-485-5p	CLIP-seq
MIRT818144	hsa-miR-508-5p	CLIP-seq
MIRT818148	hsa-miR-548c-3p	CLIP-seq
MIRT818150	hsa-miR-548s	CLIP-seq
MIRT818152	hsa-miR-582-5p	CLIP-seq
MIRT1941840	hsa-miR-603	CLIP-seq
MIRT818154	hsa-miR-627	CLIP-seq
MIRT818155	hsa-miR-628-3p	CLIP-seq
MIRT2180707	hsa-miR-656	CLIP-seq
MIRT818156	hsa-miR-661	CLIP-seq
MIRT818157	hsa-miR-665	CLIP-seq
MIRT818158	hsa-miR-766	CLIP-seq
MIRT2180708	hsa-miR-921	CLIP-seq
MIRT818118	hsa-miR-3647-3p	CLIP-seq
MIRT818104	hsa-miR-105	CLIP-seq
MIRT2484128	hsa-miR-106a	CLIP-seq
MIRT2484129	hsa-miR-106b	CLIP-seq
MIRT2484130	hsa-miR-1179	CLIP-seq
MIRT818105	hsa-miR-1182	CLIP-seq
MIRT2484131	hsa-miR-122	CLIP-seq
MIRT818108	hsa-miR-129-5p	CLIP-seq
MIRT818109	hsa-miR-151-3p	CLIP-seq
MIRT2484132	hsa-miR-17	CLIP-seq
MIRT1545719	hsa-miR-187	CLIP-seq
MIRT2484133	hsa-miR-20a	CLIP-seq
MIRT2484134	hsa-miR-20b	CLIP-seq
MIRT2484135	hsa-miR-219-2-3p	CLIP-seq
MIRT818110	hsa-miR-2278	CLIP-seq
MIRT2484136	hsa-miR-302a	CLIP-seq
MIRT2484137	hsa-miR-302b	CLIP-seq
MIRT2484138	hsa-miR-302c	CLIP-seq
MIRT2484139	hsa-miR-302d	CLIP-seq
MIRT2484140	hsa-miR-302e	CLIP-seq
MIRT818111	hsa-miR-3121-3p	CLIP-seq
MIRT2484141	hsa-miR-3136-3p	CLIP-seq
MIRT2484142	hsa-miR-3148	CLIP-seq
MIRT2484143	hsa-miR-33a	CLIP-seq
MIRT2484144	hsa-miR-33b	CLIP-seq
MIRT2484145	hsa-miR-34a	CLIP-seq
MIRT2484146	hsa-miR-34c-5p	CLIP-seq
MIRT2484147	hsa-miR-3591-3p	CLIP-seq
MIRT2484148	hsa-miR-3613-3p	CLIP-seq
MIRT818118	hsa-miR-3647-3p	CLIP-seq
MIRT818119	hsa-miR-3671	CLIP-seq
MIRT2484149	hsa-miR-3689d	CLIP-seq
MIRT818120	hsa-miR-371-5p	CLIP-seq
MIRT818121	hsa-miR-371b-5p	CLIP-seq
MIRT2484150	hsa-miR-372	CLIP-seq
MIRT2484151	hsa-miR-373	CLIP-seq
MIRT818122	hsa-miR-384	CLIP-seq
MIRT2484152	hsa-miR-3915	CLIP-seq
MIRT2484153	hsa-miR-3925-3p	CLIP-seq
MIRT2484154	hsa-miR-3928	CLIP-seq
MIRT2180698	hsa-miR-3929	CLIP-seq
MIRT2484155	hsa-miR-3938	CLIP-seq
MIRT818124	hsa-miR-3976	CLIP-seq
MIRT818125	hsa-miR-4252	CLIP-seq
MIRT2180699	hsa-miR-4255	CLIP-seq
MIRT818127	hsa-miR-4282	CLIP-seq
MIRT2484156	hsa-miR-4311	CLIP-seq
MIRT2180702	hsa-miR-4326	CLIP-seq
MIRT2484157	hsa-miR-4328	CLIP-seq
MIRT2180703	hsa-miR-4419b	CLIP-seq
MIRT2484158	hsa-miR-4443	CLIP-seq
MIRT818131	hsa-miR-4470	CLIP-seq
MIRT1941836	hsa-miR-4474-5p	CLIP-seq
MIRT2180704	hsa-miR-4478	CLIP-seq
MIRT818132	hsa-miR-4486	CLIP-seq
MIRT2484159	hsa-miR-449a	CLIP-seq
MIRT2484160	hsa-miR-449b	CLIP-seq
MIRT818135	hsa-miR-451b	CLIP-seq
MIRT818136	hsa-miR-4635	CLIP-seq
MIRT818137	hsa-miR-4649-5p	CLIP-seq
MIRT2484161	hsa-miR-4666-5p	CLIP-seq
MIRT2484162	hsa-miR-4668-3p	CLIP-seq
MIRT818138	hsa-miR-4684-5p	CLIP-seq
MIRT2484163	hsa-miR-4687-3p	CLIP-seq
MIRT2180705	hsa-miR-4691-5p	CLIP-seq
MIRT818139	hsa-miR-4696	CLIP-seq
MIRT2484164	hsa-miR-4712-5p	CLIP-seq
MIRT818141	hsa-miR-4719	CLIP-seq
MIRT2484165	hsa-miR-4768-5p	CLIP-seq
MIRT2484166	hsa-miR-4787-3p	CLIP-seq
MIRT818142	hsa-miR-4793-3p	CLIP-seq
MIRT2180706	hsa-miR-485-5p	CLIP-seq
MIRT2484167	hsa-miR-494	CLIP-seq
MIRT2484168	hsa-miR-500a	CLIP-seq
MIRT818144	hsa-miR-508-5p	CLIP-seq
MIRT818145	hsa-miR-513a-3p	CLIP-seq
MIRT818146	hsa-miR-513c	CLIP-seq
MIRT818147	hsa-miR-514b-5p	CLIP-seq
MIRT2484169	hsa-miR-519d	CLIP-seq
MIRT2484170	hsa-miR-520a-3p	CLIP-seq
MIRT2484171	hsa-miR-520b	CLIP-seq
MIRT2484172	hsa-miR-520c-3p	CLIP-seq
MIRT2484173	hsa-miR-520d-3p	CLIP-seq
MIRT2484174	hsa-miR-520e	CLIP-seq
MIRT2484175	hsa-miR-520f	CLIP-seq
MIRT2484176	hsa-miR-548ac	CLIP-seq
MIRT2484177	hsa-miR-548ae	CLIP-seq
MIRT2484178	hsa-miR-548aj	CLIP-seq
MIRT2484179	hsa-miR-548am	CLIP-seq
MIRT818148	hsa-miR-548c-3p	CLIP-seq
MIRT2484180	hsa-miR-548d-3p	CLIP-seq
MIRT818151	hsa-miR-548u	CLIP-seq
MIRT2484181	hsa-miR-548x	CLIP-seq
MIRT2484182	hsa-miR-548z	CLIP-seq
MIRT2484183	hsa-miR-583	CLIP-seq
MIRT2484184	hsa-miR-586	CLIP-seq
MIRT1941840	hsa-miR-603	CLIP-seq
MIRT2484185	hsa-miR-607	CLIP-seq
MIRT2484186	hsa-miR-622	CLIP-seq
MIRT818155	hsa-miR-628-3p	CLIP-seq
MIRT2180707	hsa-miR-656	CLIP-seq
MIRT818156	hsa-miR-661	CLIP-seq
MIRT818158	hsa-miR-766	CLIP-seq
MIRT2484187	hsa-miR-770-5p	CLIP-seq
MIRT2484188	hsa-miR-93	CLIP-seq
MIRT818104	hsa-miR-105	CLIP-seq
MIRT2484128	hsa-miR-106a	CLIP-seq
MIRT2484129	hsa-miR-106b	CLIP-seq
MIRT2484130	hsa-miR-1179	CLIP-seq
MIRT818105	hsa-miR-1182	CLIP-seq
MIRT2484131	hsa-miR-122	CLIP-seq
MIRT818108	hsa-miR-129-5p	CLIP-seq
MIRT818109	hsa-miR-151-3p	CLIP-seq
MIRT2484132	hsa-miR-17	CLIP-seq
MIRT2484133	hsa-miR-20a	CLIP-seq
MIRT2484134	hsa-miR-20b	CLIP-seq
MIRT818110	hsa-miR-2278	CLIP-seq
MIRT2484136	hsa-miR-302a	CLIP-seq
MIRT2484137	hsa-miR-302b	CLIP-seq
MIRT2484138	hsa-miR-302c	CLIP-seq
MIRT2484139	hsa-miR-302d	CLIP-seq
MIRT2484140	hsa-miR-302e	CLIP-seq
MIRT818111	hsa-miR-3121-3p	CLIP-seq
MIRT2484141	hsa-miR-3136-3p	CLIP-seq
MIRT2484142	hsa-miR-3148	CLIP-seq
MIRT2484143	hsa-miR-33a	CLIP-seq
MIRT2484144	hsa-miR-33b	CLIP-seq
MIRT2484147	hsa-miR-3591-3p	CLIP-seq
MIRT2484148	hsa-miR-3613-3p	CLIP-seq
MIRT818118	hsa-miR-3647-3p	CLIP-seq
MIRT818119	hsa-miR-3671	CLIP-seq
MIRT2484149	hsa-miR-3689d	CLIP-seq
MIRT818120	hsa-miR-371-5p	CLIP-seq
MIRT818121	hsa-miR-371b-5p	CLIP-seq
MIRT2484150	hsa-miR-372	CLIP-seq
MIRT2484151	hsa-miR-373	CLIP-seq
MIRT818122	hsa-miR-384	CLIP-seq
MIRT2484152	hsa-miR-3915	CLIP-seq
MIRT2484153	hsa-miR-3925-3p	CLIP-seq
MIRT2484154	hsa-miR-3928	CLIP-seq
MIRT2484155	hsa-miR-3938	CLIP-seq
MIRT818124	hsa-miR-3976	CLIP-seq
MIRT818125	hsa-miR-4252	CLIP-seq
MIRT2180699	hsa-miR-4255	CLIP-seq
MIRT818127	hsa-miR-4282	CLIP-seq
MIRT2484156	hsa-miR-4311	CLIP-seq
MIRT2180702	hsa-miR-4326	CLIP-seq
MIRT2484158	hsa-miR-4443	CLIP-seq
MIRT818131	hsa-miR-4470	CLIP-seq
MIRT818132	hsa-miR-4486	CLIP-seq
MIRT818135	hsa-miR-451b	CLIP-seq
MIRT818136	hsa-miR-4635	CLIP-seq
MIRT818137	hsa-miR-4649-5p	CLIP-seq
MIRT2484161	hsa-miR-4666-5p	CLIP-seq
MIRT2484162	hsa-miR-4668-3p	CLIP-seq
MIRT818138	hsa-miR-4684-5p	CLIP-seq
MIRT2484163	hsa-miR-4687-3p	CLIP-seq
MIRT2180705	hsa-miR-4691-5p	CLIP-seq
MIRT818139	hsa-miR-4696	CLIP-seq
MIRT2484164	hsa-miR-4712-5p	CLIP-seq
MIRT818141	hsa-miR-4719	CLIP-seq
MIRT2484165	hsa-miR-4768-5p	CLIP-seq
MIRT818142	hsa-miR-4793-3p	CLIP-seq
MIRT2180706	hsa-miR-485-5p	CLIP-seq
MIRT2484167	hsa-miR-494	CLIP-seq
MIRT2484168	hsa-miR-500a	CLIP-seq
MIRT818144	hsa-miR-508-5p	CLIP-seq
MIRT818145	hsa-miR-513a-3p	CLIP-seq
MIRT818146	hsa-miR-513c	CLIP-seq
MIRT818147	hsa-miR-514b-5p	CLIP-seq
MIRT2484169	hsa-miR-519d	CLIP-seq
MIRT2484170	hsa-miR-520a-3p	CLIP-seq
MIRT2484171	hsa-miR-520b	CLIP-seq
MIRT2484172	hsa-miR-520c-3p	CLIP-seq
MIRT2484173	hsa-miR-520d-3p	CLIP-seq
MIRT2484174	hsa-miR-520e	CLIP-seq
MIRT2484175	hsa-miR-520f	CLIP-seq
MIRT2484176	hsa-miR-548ac	CLIP-seq
MIRT2484177	hsa-miR-548ae	CLIP-seq
MIRT2484178	hsa-miR-548aj	CLIP-seq
MIRT2484179	hsa-miR-548am	CLIP-seq
MIRT2484180	hsa-miR-548d-3p	CLIP-seq
MIRT818151	hsa-miR-548u	CLIP-seq
MIRT2484181	hsa-miR-548x	CLIP-seq
MIRT2484182	hsa-miR-548z	CLIP-seq
MIRT2484183	hsa-miR-583	CLIP-seq
MIRT2484184	hsa-miR-586	CLIP-seq
MIRT2484185	hsa-miR-607	CLIP-seq
MIRT2484186	hsa-miR-622	CLIP-seq
MIRT818155	hsa-miR-628-3p	CLIP-seq
MIRT818156	hsa-miR-661	CLIP-seq
MIRT818158	hsa-miR-766	CLIP-seq
MIRT2484187	hsa-miR-770-5p	CLIP-seq
MIRT2484188	hsa-miR-93	CLIP-seq

Show/Hide all(91)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001772	Component	Immunological synapse	IEA
GO:0001783	Process	B cell apoptotic process	IEA
GO:0001819	Process	Positive regulation of cytokine production	IEA
GO:0001843	Process	Neural tube closure	IEA
GO:0001843	Process	Neural tube closure	ISS	11163238
GO:0002020	Function	Protease binding	IPI	18223652
GO:0002096	Component	Polkadots	IEA
GO:0002224	Process	Toll-like receptor signaling pathway	IDA	16831874
GO:0002250	Process	Adaptive immune response	IBA
GO:0002250	Process	Adaptive immune response	IEA
GO:0002250	Process	Adaptive immune response	IMP	25365219
GO:0002250	Process	Adaptive immune response	TAS	16831874
GO:0002376	Process	Immune system process	IEA
GO:0002906	Process	Negative regulation of mature B cell apoptotic process	IDA	15878976
GO:0003713	Function	Transcription coactivator activity	IBA
GO:0003713	Function	Transcription coactivator activity	IDA	15207693
GO:0005515	Function	Protein binding	IPI	10187771, 11053425, 11259443, 11278692, 11466612, 11472070, 12154360, 14695475, 16280327, 16809782, 16831874, 17052756, 17363905, 17948050, 18287044, 19118383, 19444310, 19815501, 21157432, 22267217, 22528498, 24412244, 25011391, 25416956, 25910212, 26488816, 27070702, 27071417, 271
GO:0005634	Component	Nucleus	IDA	16280327
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IDA	11021819, 11053425, 11238466, 11278692, 15082780
GO:0005737	Component	Cytoplasm	IEA
GO:0005764	Component	Lysosome	IDA	15082780
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA	12154360, 16831874
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005881	Component	Cytoplasmic microtubule	IDA	23264731
GO:0006915	Process	Apoptotic process	IEA
GO:0006968	Process	Cellular defense response	IEA
GO:0009620	Process	Response to fungus	IEA
GO:0012501	Process	Programmed cell death	IDA	10400625
GO:0016020	Component	Membrane	IEA
GO:0016064	Process	Immunoglobulin mediated immune response	IEA
GO:0019209	Function	Kinase activator activity	IBA
GO:0019209	Function	Kinase activator activity	IDA	15125833
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	15125833
GO:0031398	Process	Positive regulation of protein ubiquitination	IDA	14695475
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	16395405
GO:0031663	Process	Lipopolysaccharide-mediated signaling pathway	IDA	16831874
GO:0032094	Process	Response to food	IDA	17095757
GO:0032449	Component	CBM complex	IBA
GO:0032449	Component	CBM complex	IDA	24074955, 28628108
GO:0032449	Component	CBM complex	IEA
GO:0032449	Component	CBM complex	NAS	15125833
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0032755	Process	Positive regulation of interleukin-6 production	NAS	16647297
GO:0032757	Process	Positive regulation of interleukin-8 production	IMP	17095757
GO:0032761	Process	Positive regulation of lymphotoxin A production	NAS	16647297
GO:0032765	Process	Positive regulation of mast cell cytokine production	NAS	16647297
GO:0032991	Component	Protein-containing complex	IDA	14695475, 16280327, 22267217
GO:0032991	Component	Protein-containing complex	IEA
GO:0035591	Function	Signaling adaptor activity	IEA
GO:0038061	Process	Non-canonical NF-kappaB signal transduction	IEA
GO:0042327	Process	Positive regulation of phosphorylation	IDA	15125833
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	10187771, 25416956, 32296183
GO:0042802	Function	Identical protein binding	ISS	16831874
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0043065	Process	Positive regulation of apoptotic process	IDA	11821383
GO:0043065	Process	Positive regulation of apoptotic process	IEA
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	18223652
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IDA	18287044, 27777308
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IEP	12761501
GO:0043422	Function	Protein kinase B binding	IBA
GO:0043422	Function	Protein kinase B binding	IPI	16280327
GO:0044877	Function	Protein-containing complex binding	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0045087	Process	Innate immune response	IEP	16831874
GO:0045121	Component	Membrane raft	IEA
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	15207693
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	16127295
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0050700	Function	CARD domain binding	IEA
GO:0050852	Process	T cell receptor signaling pathway	IDA	15125833
GO:0050856	Process	Regulation of T cell receptor signaling pathway	IEA
GO:0050862	Process	Positive regulation of T cell receptor signaling pathway	IDA	18287044, 27777308
GO:0050870	Process	Positive regulation of T cell activation	IEA
GO:0051059	Function	NF-kappaB binding	IBA
GO:0051059	Function	NF-kappaB binding	IDA	16280327
GO:0051092	Process	Positive regulation of NF-kappaB transcription factor activity	IDA	10400625, 14695475, 18287044, 24074955, 27777308
GO:0051260	Process	Protein homooligomerization	IDA	24074955
GO:0061760	Process	Antifungal innate immune response	IEA
GO:0061760	Process	Antifungal innate immune response	ISS
GO:0070231	Process	T cell apoptotic process	IEA
GO:0071222	Process	Cellular response to lipopolysaccharide	IEP	16831874
GO:0071260	Process	Cellular response to mechanical stimulus	IEP	19593445
GO:0097190	Process	Apoptotic signaling pathway	IMP	22267217
GO:0140296	Function	General transcription initiation factor binding	IPI	15207693
GO:2001238	Process	Positive regulation of extrinsic apoptotic signaling pathway	IBA
GO:2001238	Process	Positive regulation of extrinsic apoptotic signaling pathway	IDA	11466612
GO:2001238	Process	Positive regulation of extrinsic apoptotic signaling pathway	IEA

MIM	HGNC	e!Ensembl
603517	989	ENSG00000142867

Protein

UniProt ID

O95999

Protein name

B-cell lymphoma/leukemia 10 (B-cell CLL/lymphoma 10) (Bcl-10) (CARD-containing molecule enhancing NF-kappa-B) (CARD-like apoptotic protein) (hCLAP) (CED-3/ICH-1 prodomain homologous E10-like regulator) (CIPER) (Cellular homolog of vCARMEN) (cCARMEN) (Cell

Protein function

Plays a key role in both adaptive and innate immune signaling by bridging CARD domain-containing proteins to immune activation (PubMed:10187770, PubMed:10364242, PubMed:10400625, PubMed:24074955, PubMed:25365219). Acts by channeling adaptive and

PDB

2MB9 , 6BZE , 6GK2 , 8CZD , 8CZO

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00619	CARD	18 → 102	Caspase recruitment domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:9989495}.

Sequence

MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTS
SRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCS
SCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVG
RTENTIFSSTTLPRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ

Sequence length

233

Interactions

View interactions

	KEGG		Reactome
	NF-kappa B signaling pathway C-type lectin receptor signaling pathway T cell receptor signaling pathway B cell receptor signaling pathway Shigellosis Tuberculosis		Activation of NF-kappaB in B cells Downstream TCR signaling FCERI mediated NF-kB activation CLEC7A (Dectin-1) signaling E3 ubiquitin ligases ubiquitinate target proteins

Show/Hide Causal Diseases (6)

Disease merge term	Disease name	dbSNP ID	References
Causal Diseases caused by PATHOGENIC or LIKELY PATHOGENIC variants from ClinVar only
Immunodeficiency	immunodeficiency 37	rs121918314, rs606231305	N/A
Follicular lymphoma	follicular lymphoma	rs587776634, rs587776635, rs587776636, rs587776637, rs587776632, rs587776633	N/A
Lymphoblastic Leukemia	T-cell acute lymphoblastic leukemia	rs387906351	N/A
Mesothelioma	mesothelioma	rs387906350, rs387906351	N/A
mucosa-associated lymphoma	Mucosa-associated lymphoma	rs387906350, rs587776630, rs587776631	N/A
Sezary Syndrome	sezary syndrome	rs587776632	N/A

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Alzheimer disease	Alzheimer's disease or family history of Alzheimer's disease	N/A	N/A	GWAS
Multiple Sclerosis	Multiple sclerosis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (36)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Alzheimer Disease	Associate	36334414
Asthma	Associate	32900903, 37259023
Behcet Syndrome	Associate	26890122
Breast Neoplasms	Associate	16280327, 32746451
Carcinogenesis	Associate	10886211, 24732096, 26771713
Carcinoma Hepatocellular	Associate	34928543
Colorectal Neoplasms	Associate	35352485
COVID 19	Associate	36334414
Dementia	Inhibit	36334414
Endometriosis	Associate	29511377
Familial Mediterranean Fever	Associate	37140617
Gallbladder Neoplasms	Associate	18497548
Immunologic Deficiency Syndromes	Associate	11387339, 34868072
Inflammation	Associate	19714753, 21700900, 22579587, 23784377, 37140617
Intraocular Lymphoma	Associate	16799010
Leprosy	Associate	23784377, 34879060
Leprosy	Inhibit	23784377
Lymphoma	Associate	10845924, 11262391, 11493468, 16177990, 16636680, 23661444
Lymphoma B Cell	Associate	10583229, 10665648, 10845924, 10886211, 18628489
Lymphoma B Cell Marginal Zone	Associate	10665648, 10845924, 10886211, 11021819, 11356195, 11387339, 11493468, 11830492, 12517817, 15143341, 15845895, 16280327, 16341151, 16395405, 16636680 View all (12 more)
Lymphoma Follicular	Associate	10583229
Lymphoma Large B Cell Diffuse	Associate	18628489, 19841089, 27777308, 35658124
Lymphoma Non Hodgkin	Associate	10886211
Mouth Neoplasms	Associate	20695076
Neoplasms	Associate	10408399, 10408401, 10583229, 10886211, 11021819, 11167747, 11493468, 15845895, 16280327, 19709433, 22474286, 23807165, 24732096, 26771713, 29084984, 29511377, 34928543, 35352485 View all (3 more)
Precursor Cell Lymphoblastic Leukemia Lymphoma	Associate	25384343
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	10583229, 24329526, 25384343
Pseudolymphoma	Associate	23661444
Psoriasis	Associate	27071417
Severe Acute Respiratory Syndrome	Associate	26893103
Sezary Syndrome	Associate	10583229
Stomach Neoplasms	Associate	20205286
Teratoma	Associate	23918355
Triple Negative Breast Neoplasms	Associate	29440447
Uterine Cervical Neoplasms	Associate	34928543
Waldenstrom Macroglobulinemia	Associate	16636680

BCL10 (BCL10 immune signaling adaptor)