Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	8908
Gene name Gene Name - the full gene name approved by the HGNC.	Glycogenin 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	GYG2
Synonyms (NCBI Gene) Gene synonyms aliases	GN-2, GN2
Chromosome Chromosome number	X
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	Xp22.33
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a member of the the glycogenin family. Glycogenin is a self-glucosylating protein involved in the initiation reactions of glycogen biosynthesis. A gene on chromosome 3 encodes the muscle glycogenin and this X-linked gene encodes the glyc

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miRTarBase ID	miRNA	Experiments	Reference
MIRT030406	hsa-miR-24-3p	Microarray	19748357
MIRT709568	hsa-miR-4267	HITS-CLIP	19536157
MIRT709567	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT709566	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709565	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709564	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709563	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT709562	hsa-miR-5001-3p	HITS-CLIP	19536157
MIRT709561	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709568	hsa-miR-4267	HITS-CLIP	19536157
MIRT709567	hsa-miR-4772-3p	HITS-CLIP	19536157
MIRT709566	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709565	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709564	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709563	hsa-miR-2355-5p	HITS-CLIP	19536157
MIRT709562	hsa-miR-5001-3p	HITS-CLIP	19536157
MIRT709561	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT1038872	hsa-miR-125a-5p	CLIP-seq
MIRT1038873	hsa-miR-125b	CLIP-seq
MIRT1038874	hsa-miR-4319	CLIP-seq
MIRT1038875	hsa-miR-4446-5p	CLIP-seq
MIRT1038876	hsa-miR-4732-3p	CLIP-seq
MIRT1038877	hsa-miR-4755-5p	CLIP-seq
MIRT1038878	hsa-miR-670	CLIP-seq
MIRT2007980	hsa-let-7a	CLIP-seq
MIRT2007981	hsa-let-7b	CLIP-seq
MIRT2007982	hsa-let-7c	CLIP-seq
MIRT2007983	hsa-let-7d	CLIP-seq
MIRT2007984	hsa-let-7e	CLIP-seq
MIRT2007985	hsa-let-7f	CLIP-seq
MIRT2007986	hsa-let-7g	CLIP-seq
MIRT2007987	hsa-let-7i	CLIP-seq
MIRT2007988	hsa-miR-146a	CLIP-seq
MIRT2007989	hsa-miR-146b-5p	CLIP-seq
MIRT2007990	hsa-miR-196a	CLIP-seq
MIRT2007991	hsa-miR-196b	CLIP-seq
MIRT2007992	hsa-miR-202	CLIP-seq
MIRT2007993	hsa-miR-2277-3p	CLIP-seq
MIRT2007994	hsa-miR-3150b-3p	CLIP-seq
MIRT2007995	hsa-miR-3174	CLIP-seq
MIRT2007996	hsa-miR-3615	CLIP-seq
MIRT2007997	hsa-miR-3660	CLIP-seq
MIRT2007998	hsa-miR-4458	CLIP-seq
MIRT2007999	hsa-miR-4500	CLIP-seq
MIRT2008000	hsa-miR-4526	CLIP-seq
MIRT2008001	hsa-miR-4639-3p	CLIP-seq
MIRT1038876	hsa-miR-4732-3p	CLIP-seq
MIRT2008002	hsa-miR-4784	CLIP-seq
MIRT2008003	hsa-miR-663b	CLIP-seq
MIRT2008004	hsa-miR-921	CLIP-seq
MIRT2008005	hsa-miR-98	CLIP-seq
MIRT2240685	hsa-miR-335	CLIP-seq
MIRT2240686	hsa-miR-4786-5p	CLIP-seq
MIRT2544185	hsa-miR-3185	CLIP-seq
MIRT2544185	hsa-miR-3185	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	16189514, 33961781, 35271311
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005737	Component	Cytoplasm	ISS
GO:0005829	Component	Cytosol	TAS
GO:0005978	Process	Glycogen biosynthetic process	IDA	9857012
GO:0005978	Process	Glycogen biosynthetic process	IEA
GO:0005978	Process	Glycogen biosynthetic process	TAS
GO:0008466	Function	Glycogenin glucosyltransferase activity	EXP	9346895
GO:0008466	Function	Glycogenin glucosyltransferase activity	IDA	9857012
GO:0008466	Function	Glycogenin glucosyltransferase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016757	Function	Glycosyltransferase activity	IBA
GO:0016757	Function	Glycosyltransferase activity	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
300198	4700	ENSG00000056998

Protein

UniProt ID

O15488

Protein name

Glycogenin-2 (GN-2) (GN2) (EC 2.4.1.186)

Protein function

Glycogenin participates in the glycogen biosynthetic process along with glycogen synthase and glycogen branching enzyme. It catalyzes the formation of a short alpha (1,4)-glucosyl chain covalently attached via a glucose 1-O-tyrosyl linkage to in

PDB

4UEG

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01501	Glyco_transf_8	39 → 257	Glycosyl transferase family 8	Family

Tissue specificity

TISSUE SPECIFICITY: Detected in liver (at protein level) (PubMed:9857012). Expressed preferentially in liver, heart, and pancreas (PubMed:9346895). {ECO:0000269|PubMed:9346895, ECO:0000269|PubMed:9857012}.

Sequence

MSETEFHHGAQAGLELLRSSNSPTSASQSAGMTVTDQAFVTLATNDIYCQGALVLGQSLR
RHRLTRKLVVLITPQVSSLLRVILSKVFDEVIEVNLIDSADYIHLAFLKRPELGLTLTKL
HCWTLTHYSKCVFLDADTLVLSNVDELFDRGEFSAAPDPGWPDCFNSGVFVFQPSLHTHK
LLLQHAMEHGSFDGADQGLLNSFFRNWSTTDIHKHLPFIYNLSSNTMYTYSPAFKQFGSS
AKVVHFLGSMKPWNYKYNPQSGSVLEQGSASSSQHQAAFLHLWWTVYQNNVLPLYKSVQA
GEARASPGHTLCHSDVGGPCADSASGVGEPCENSTPSAGVPCANSPLGSNQPAQGLPEPT
QIVDETLSLPEGRRSEDMIACPETETPAVITCDPLSQPSPQPADFTETETILQPANKVES
VSSEETFEPSQELPAEALRDPSLQDALEVDLAVSVSQISIEEKVKELSPEEERRKWEEGR
IDYMGKDAFARIQEKLDRFLQ

Sequence length

501

Interactions

View interactions

	KEGG		Reactome
	Starch and sucrose metabolism Metabolic pathways		Glycogen synthesis Glycogen storage disease type 0 (liver GYS2) Glycogen storage disease type IV (GBE1) Glycogen breakdown (glycogenolysis)

GYG2 (glycogenin 2)